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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan97/breast-cancer-screening-january-2016
July 17, 2014 - lesions (ductal or lobular carcinoma in situ, atypical ductal or lobular hyperplasia); or previous large … lesions (ductal or lobular carcinoma in situ, atypical ductal or lobular hyperplasia); or previous large … ductal or lobular carcinoma in situ, atypical ductal or lobular hyperplasia); or women with previous large
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/syphilis-infection-pregnant-persons
December 01, 2022 - Randomized, controlled trials; cohort studies; case-control studies; diagnostic accuracy studies; large
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan154/healthful-diet-and-physical-activity-for-cardiovascular-disease-prevention-in-adults-without-known-risk-factors-behavioral-counseling
May 14, 2015 - reviews, individual and cluster RCTs, nonrandomized CCTs
KQ 4: Systematic reviews, RCTs, CCTs, large … comparative cohort or case-control studies with appropriate comparison group, large event-monitoring
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www.uspreventiveservicestaskforce.org/uspstf/document/published-comment---will-recommendations-against-spirometry-make-chronic-obstructive-pulmonary-disease-harder-to-treat/chronic-obstructive-pulmonary-disease-copd-screening
November 15, 2008 - Preventive Services Task Force (USPSTF) clinical summary figure, in large bold letters, states: "Do not … Specifically, not only are most patients with COPD without diagnosis, but a large proportion of individuals
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www.uspreventiveservicestaskforce.org/uspstf/document/published-comment---will-recommendations-against-spirometry-make-chronic-obstructive-pulmonary-disease-harder-to-treat/chronic-obstructive-pulmonary-disease-copd-screening-2008
November 15, 2008 - Preventive Services Task Force (USPSTF) clinical summary figure, in large bold letters, states: "Do not … Specifically, not only are most patients with COPD without diagnosis, but a large proportion of individuals
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan154/healthful-diet-and-physical-activity-for-cardiovascular-disease-prevention-in-adults-without-known-risk-factors-behavioral-counseling-july-2017
May 14, 2015 - reviews, individual and cluster RCTs, nonrandomized CCTs
KQ 4: Systematic reviews, RCTs, CCTs, large … comparative cohort or case-control studies with appropriate comparison group, large event-monitoring
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/atrial-fibrillation-screening-with-electrocardiography-august-2018
July 14, 2016 - Study designs
All KQs: Randomized, controlled trials and controlled clinical trials
KQs 5, 6: Large … eligible
KQ 8: Systematic reviews * of trials, systematic reviews * of observational studies, and large
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-bleeding-risks-with-aspirin-use/aspirin-to-prevent-cardiovascular-disease-and-cancer
April 11, 2016 - reviewed abstracts and full-text articles against prespecified criteria. 5 We included trials and large … Most relevant cohort data came from a large good-quality Italian study examining hospitalizations for … lack of evaluation of dosage effects, 22 or issues with exposure measurement. 33 , 34 In the 2 large … For example, we found little data beyond 1 large cohort study to update a commonly cited baseline rate … Large-scale randomized, controlled trials are required to determine the effect of such strategies on
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-bleeding-risks-with-aspirin-use/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
April 11, 2016 - reviewed abstracts and full-text articles against prespecified criteria. 5 We included trials and large … Most relevant cohort data came from a large good-quality Italian study examining hospitalizations for … lack of evaluation of dosage effects, 22 or issues with exposure measurement. 33 , 34 In the 2 large … For example, we found little data beyond 1 large cohort study to update a commonly cited baseline rate … Large-scale randomized, controlled trials are required to determine the effect of such strategies on
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/pskqLZMFcHjhtEF75uG4AP
January 01, 2012 - its development was supported by a broad interna-
tional collaboration and extensively validated in 2 large … Potential Preventable Burden
Bone measurement tests may detect osteoporosis in a
large number of men … Because a large and diverse sample was used to develop
and validate the FRAX tool and this instrument … Two large placebo-
controlled trials of raloxifene reported reduced vertebral
fractures, with a combined … One large case–control study in Denmark showed
an increased risk for atrial fibrillation with any use
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/ocular-prophylaxis-for-gonococcal-ophthalmia-neonatorum-preventive-medication
February 08, 2018 - controlled trials; systematic reviews and meta-analyses; cohort studies, case-control studies, and large
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/inevidup.pdf
September 01, 2009 - Even for screening topics that
pertain to all or a large majority of adults, children, or
adolescents … the strongest argument for providing an intervention
is based on scientific evidence from multiple large … Insufficient Evidence Statements for Screening of
Large Population Subgroups*
In the case of skin … When evidence is insufficient, an intervention with a
large potential for harm (such as major surgery … The potential harms from evaluation of incidental findings found with CT colonography may be large.
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/prostate-cancer-screening
May 08, 2018 - This is known as overdiagnosis, and follow-up of large randomized trials suggests that 20% to 50% of … Screening
PSA-based screening is the usual method of screening and has been studied in several large … PSA-based screening for prostate cancer has been studied in 3 very large RCTs, each with at least a decade … The 3 large RCTs on screening predominantly included men aged 55 to 69 years. … The effect of study arm on prostate cancer treatment in the large screening trial ERSPC.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/TEqfQsqZ92eykPeTQBZx-h
March 12, 2012 - Screening with cytology more often than every 3 years confers little additional benefit, with large increases
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/pnyU5fxhdBUtCdvJ3GyqzR
March 01, 2007 - Mortality
The Woman’s Health Study (WHS) (32) was a large
good-quality RCT in which female health care … A large, good-
quality, long-term follow-up study of aspirin use in aver-
age-risk U.S. women revealed … One systematic review pooled gas-
trointestinal bleeding incidence among large cardiovascular
studies … Aspirin use, cancer, and polyps of the large
bowel. Cancer. 1993;72:1171-7. [PMID: 8339210]
20. … Reduced
risk of large-bowel adenomas among aspirin users. The Polyp Prevention Study
Group.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/3qpQqeeozW8nV3a4_BWntp
June 20, 2019 - Infection with HIV causes immune deficiency to a large
extent by decreasing the level and function of … A large study of HIV testing in
752 U.S. laboratories reported a sensitivity of 99.7% and
specificity … Two large (n � 3570 and n � 4442), good-quality
studies of the OraSure Oral Specimen Collection Device … Differences in
prescription of antiretroviral therapy in a large cohort of HIV-infected patients. … The estimated prevalence and incidence of HIV in 96
large US metropolitan areas.
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www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/chronic-obstructive-pulmonary-disease-screening1
November 02, 2021 - One large randomized, controlled trial (SUMMIT; n=16,590) in persons with or at risk for cardiovascular … However, large observational studies in screen-relevant populations suggest possible harms for LAMA or … Given the opportunity costs associated with screening asymptomatic persons may be large, the USPSTF bounds
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/postmenopausal-hormone-prophylaxis-preventive-medication-1996
January 01, 1996 - Controlled trials of the effects of hormone therapy on clinical endpoints are difficult because of the large … of estrogen therapy, but the importance of this physiologic effect remains controversial. 12 In a large … There was no evidence of an effect of past or current estrogen therapy on cognitive function in a large … 86 Estrogen-progestin therapy was associated with modest but significant increases in risk in three large … Postmenopausal hormone use and cholecystectomy in a large prospective study.
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www.uspreventiveservicestaskforce.org/uspstf/individualizing-cancer-screening-older-adults
October 01, 2017 - Future research should look at large longitudinal population studies such as registries, cohort studies … all treatments adversely affected urinary and sexual function. 40 This is an example of how using large
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/human-immunodeficiency-virus-hiv-infection-screeni
July 05, 2005 - In a large ( n = 1,160), good-quality Swiss cohort study of adverse events in clinical practice, 47% … Differences in prescription of antiretroviral therapy in a large cohort of HIV-infected patients. … The estimated prevalence and incidence of HIV in 96 large US metropolitan areas. … Randomized, controlled trials; large cohort studies
Fair for pneumococcal, influenza, and hepatitis … Randomized, controlled trials; large cohort studies
Good overall
Good-quality systematic reviews