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  1. effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
    September 21, 2012 - Pragmatic trials are large and simple experiments on treatments, with broad eligibility criteria, from … sample size required for detecting ATE of a particular size, a sample size roughly four times as large … of the same magnitude as ATE for a 50:50 subgroup split; a sample size approximately 16 times as large … the potential for subgroup analyses (and implied HTE) to lead to erroneous inferences came from a large … be viewed as an extreme version of subgroup analysis, where individuals are cross-classified by a large
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/evidence-examples_white-paper.pdf
    April 01, 2014 - In spite of a fairly large number of head-to-head comparison RCTs for efficacy and effectiveness, public … Precise effect estimate across included studies • Additional Domains: • Strength of association: Large … Finally, a large magnitude of effect and precise estimate was seen across all included studies: the … of performance bias: Objective primary outcome • Additional Domains: • Strength of association: Large … The study was prospective and adequately powered by including a large sample across multiple clinical
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-provider-adherence_executive.pdf
    May 01, 2013 - No conclusion; One study reported a large reduction, but study quality was low. … The magnitude of effect is large: 2%–34% in pre-post studies; 2%–17% in RCTs. … The magnitude of effect is large: 14%–84%. … Magnitude of effect is large in pre-post studies (41%–54%) and small in RCTs (1%–7%). … Improved asthma outcomes using a coordinated care approach in a large medical group.
  4. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence.pdf
    October 26, 2020 - Because a large number of articles were identified, we reviewed a random sample of 200 titles and abstracts … Represents a significant disease burden; large proportion of the population FI is a condition that … Is of high public interest; affects health care decision making, outcomes, or costs for a large proportion … The estimated size of a new systematic review would likely be large. 6. Value 6a.
  5. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_2.pdf
    October 26, 2020 - Because a large number of articles were identified, we reviewed a random sample of 200 titles and abstracts … Represents a significant disease burden; large proportion of the population FI is a condition that … Is of high public interest; affects health care decision making, outcomes, or costs for a large proportion … The estimated size of a new systematic review would likely be large. 6. Value 6a.
  6. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_1.pdf
    October 26, 2020 - Because a large number of articles were identified, we reviewed a random sample of 200 titles and abstracts … Represents a significant disease burden; large proportion of the population FI is a condition that … Is of high public interest; affects health care decision making, outcomes, or costs for a large proportion … The estimated size of a new systematic review would likely be large. 6. Value 6a.
  7. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_0.pdf
    October 26, 2020 - Because a large number of articles were identified, we reviewed a random sample of 200 titles and abstracts … Represents a significant disease burden; large proportion of the population FI is a condition that … Is of high public interest; affects health care decision making, outcomes, or costs for a large proportion … The estimated size of a new systematic review would likely be large. 6. Value 6a.
  8. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_12.pdf
    October 26, 2020 - Because a large number of articles were identified, we reviewed a random sample of 200 titles and abstracts … Represents a significant disease burden; large proportion of the population FI is a condition that … Is of high public interest; affects health care decision making, outcomes, or costs for a large proportion … The estimated size of a new systematic review would likely be large. 6. Value 6a.
  9. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_11.pdf
    October 26, 2020 - Because a large number of articles were identified, we reviewed a random sample of 200 titles and abstracts … Represents a significant disease burden; large proportion of the population FI is a condition that … Is of high public interest; affects health care decision making, outcomes, or costs for a large proportion … The estimated size of a new systematic review would likely be large. 6. Value 6a.
  10. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_10.pdf
    October 26, 2020 - Because a large number of articles were identified, we reviewed a random sample of 200 titles and abstracts … Represents a significant disease burden; large proportion of the population FI is a condition that … Is of high public interest; affects health care decision making, outcomes, or costs for a large proportion … The estimated size of a new systematic review would likely be large. 6. Value 6a.
  11. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_9.pdf
    October 26, 2020 - Because a large number of articles were identified, we reviewed a random sample of 200 titles and abstracts … Represents a significant disease burden; large proportion of the population FI is a condition that … Is of high public interest; affects health care decision making, outcomes, or costs for a large proportion … The estimated size of a new systematic review would likely be large. 6. Value 6a.
  12. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_8.pdf
    October 26, 2020 - Because a large number of articles were identified, we reviewed a random sample of 200 titles and abstracts … Represents a significant disease burden; large proportion of the population FI is a condition that … Is of high public interest; affects health care decision making, outcomes, or costs for a large proportion … The estimated size of a new systematic review would likely be large. 6. Value 6a.
  13. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_7.pdf
    October 26, 2020 - Because a large number of articles were identified, we reviewed a random sample of 200 titles and abstracts … Represents a significant disease burden; large proportion of the population FI is a condition that … Is of high public interest; affects health care decision making, outcomes, or costs for a large proportion … The estimated size of a new systematic review would likely be large. 6. Value 6a.
  14. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_5.pdf
    October 26, 2020 - Because a large number of articles were identified, we reviewed a random sample of 200 titles and abstracts … Represents a significant disease burden; large proportion of the population FI is a condition that … Is of high public interest; affects health care decision making, outcomes, or costs for a large proportion … The estimated size of a new systematic review would likely be large. 6. Value 6a.
  15. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_6.pdf
    October 26, 2020 - Because a large number of articles were identified, we reviewed a random sample of 200 titles and abstracts … Represents a significant disease burden; large proportion of the population FI is a condition that … Is of high public interest; affects health care decision making, outcomes, or costs for a large proportion … The estimated size of a new systematic review would likely be large. 6. Value 6a.
  16. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_4.pdf
    October 26, 2020 - Because a large number of articles were identified, we reviewed a random sample of 200 titles and abstracts … Represents a significant disease burden; large proportion of the population FI is a condition that … Is of high public interest; affects health care decision making, outcomes, or costs for a large proportion … The estimated size of a new systematic review would likely be large. 6. Value 6a.
  17. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_3.pdf
    October 26, 2020 - Because a large number of articles were identified, we reviewed a random sample of 200 titles and abstracts … Represents a significant disease burden; large proportion of the population FI is a condition that … Is of high public interest; affects health care decision making, outcomes, or costs for a large proportion … The estimated size of a new systematic review would likely be large. 6. Value 6a.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
    March 29, 2011 - What is the comparative effectiveness of large neutral amino acids (LNAAs) with dietary intervention … Large neutral amino acids in the treatment of phenylketonuria (PKU). … Large neutral amino acids supplementation in phenylketonuric patients. … Large neutral amino acids in the treatment of phenylketonuria (PKU). … Large neutral amino acids supplementation in phenylketonuric patients.
  19. effectivehealthcare.ahrq.gov/products/cervical-ripening/protocol
    January 16, 2020 - scheduling at the request of pregnant women, or to insure availability of appropriate providers. 4 A recent large … Trials; recent high quality Systematic Reviews; if RCT evidence for benefits is insufficient, include large … Trials; recent high quality Systematic Reviews; if RCT evidence for benefits is insufficient, include large … They will have a serious or “fatal” flaw in design, analysis, or reporting; large amounts of missing … These are: a dose-response is seen, a large magnitude of effect is seen (odds ratio >3), or the effect
  20. effectivehealthcare.ahrq.gov/sites/default/files/cer-245-breast-reconstruction-after-mastectomy-disposition-comments.pdf
    October 01, 2021 - risks of reconstruction with breast implants barely mentions breast implant associated anaplastic large … for this SR did not address the risk of new neoplasms, in particular implant- associated anaplastic large … reconstruction with breast implants, the draft only mentions breast implant associated anaplastic large … for this SR did not address the risk of new neoplasms, in particular implant- associated anaplastic large

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