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Total Results: 1,445 records

Showing results for "large".

1401. Treatment of Hepatitis C Virus Infection in Adults: Future Research Needs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
      April 01, 2013 - HCV is primarily acquired by large or repeated percutaneous exposures to blood, with injection drug … Mortality and long- term hepatic comp- lications A large VA hospital study that controlled well … Importance: • Represents a significant disease burden, large proportion or priority population. … • Is of high public interest; affects health care decisionmaking, outcomes, or costs for a large … Large existing registries of patients with HCV infection could be a more efficient source of data than

1402. Cancer-Pancreas Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
      September 01, 2014 - comparisons, and settings.19 In considering the applicability of the findings to patients, we consulted large … A review of MRI found only four studies and thus had a large uncertainty in its results. … The large majority of pancreas-specific studies reported the procedural harms of EUS-FNA. … worse), and tumor characteristics 17 (e.g., for staging small tumors, one test is best, but for large

1403. MEDLINE Searches (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_appendixes.pdf
      March 01, 2009 - Weight gain, body mass index, hormone replacement therapy, and postmenopausal breast cancer in a large … Recreational physical activity and risk of postmenopausal breast cancer in a large cohort of US women … Large-scale randomized evidence: large, simple trials and overviews of trials. … This additional domain should be considered if the effect size is particularly large. … Only very large, well known trials could provide the breast cancer outcomes needed for this report

1404. Comparative Effectiveness Review Disposition of Comments Report: Anxiety in Children (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/disposition-of-comments-cer-192-anxiety-in-children.pdf
      August 31, 2017 - For example, a large number of kids tend to outgrow separation anxiety disorder, although many don’ … Given this, it may be helpful for the authors to revisit some of the differences observed in this large … staggering amount of work and the authors should be commended for their attempt to synthesize such a large … There are so many small studies that are included and the large (by the field's standards) are ignored

1405. Disposition of Comments Report for The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
      September 29, 2014 - studies were rejected based upon their having a duration of observation less than 12 months, given the large … There is no question that there are a large number of individuals with chronic, non-cancer pain (CNCP … Similarly, the large prospective study in WA workers compensation on the relationship between early … concerns that the current report may be used to support policies that will reduce the ability of a large

1406. S44 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/s44.pdf
      October 01, 2007 - In addressing the first question, the most distinctive feature of DD trials emerged—the large influence … 6-month delay, we presented preliminary findings at a scientific conference.25 Generalizability A large

1407. S89 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
      October 01, 2007 - impossible to detect in prelicen- sure studies and require monitoring after introduction of the agent in large … The unique advantage of using large, linked computer- ized databases with sequential analysis is this

1408. Cerebral-Palsy-Feeding Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cerebral-palsy-feeding_executive.pdf
      March 01, 2013 - These studies have serious errors in design, analysis, or reporting; have large amounts of missing information … Of particular importance is the need to conduct large enough studies to fully characterize both participants … PEG gastrostomy tubes avoid the need for general anesthesia and a large incision.6 Percutaneous endoscopic

1409. Physiologic Predictors of Severe Injury: Systematic Review, Evidence Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-205-predictors-trauma-care-evidence-summary.pdf
      April 01, 2018 - Our findings were based on a relatively large number of diverse studies. … Analysis is also complicated by the fact that the registry studies usually have large samples, while … course and beyond, regardless of which hospital they were transported to, would help to reduce a large … , and lactate) and respiratory compromise (RR) have been evaluated in multiple studies, some with large … pressure/heart rate ratio to predict massive transfusion after severe trauma: Retrospective analysis of a large

1410. Chicago-Area DEcIDE Center (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
      May 01, 2009 - quality of existing information for that use, drug cost, extent of marketing, and time on market) for a large … Other key stakeholders included practicing specialist physicians, large group purchasers, the health … P res c ribing Data For its large size (approximately 200,000 contact records per year), national scope … Large scale attention to off-label use is also likely to require new tools, including: 1) new, clinically … identified as being critical included practicing generalist physicians, practicing specialist physicians, large

1411. Arthritis and Nontraumatic Joint Disease (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/01_arthritis_potential_high_impact_2012-12-10.pdf
      January 01, 2012 - The evidence base for PRP lacks sufficiently large, blinded, prospective, randomized controlled trials … autologous) can be isolated and expanded in vitro, providing patient-matched stem cells to treat the large … first-line therapy and actually regenerate joint cartilage and restore function, it would have a large … However, some of the experts stated that large, randomized, double-blind trials are needed to better … Experts all thought tofacitinib would have a large impact on costs, but diverged in how the impact

1412. Management of Postpartum Hemorrhage: Current State of the Evidence (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_clinician.pdf
      July 01, 2016 - PPH include grand multiparous status, previous history of PPH, prolonged second-stage labor, or a large

1413. Obesity (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1512.pdf
      December 01, 2015 - generally regarded the intragastric balloons as having moderate short-term potential to fulfill a large … Unmet need and health outcomes: Most experts recognized a moderate to large unmet need for obesity … as limiting the Orbera balloon’s potential to fill the unmet need.43 Most experts acknowledged a large … “Currently there is a large gap for the largest group of patients [with] BMI 30–34.9, and BMI 35–39.9 … Intragastric balloon as a treatment method for excess weight: a large Brazilian experience.

1414. Moyer_ECCS2012 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/moyer_eccs2012.pdf
      January 01, 2012 - Moyer_ECCS2012 Slide 1:  When Evidence-­‐Based Recommendations  Collide  With Conventional   Wisdom: Lessons  in Communication Learned by the U.S. Preventive Services   Task Force Virginia A. Moyer, M.D., M.P.H. Professor of Pediatrics Baylor College of Medicine,  Houston,  TX …

1415. Pneumonia-Antibiotic-Treatment Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
      November 01, 2014 - here on two key issues that warrant attention by health professionals, policymakers, and society at large … Future investigations could be conducted in large-scale blinded prospective designs intended to compare

1416. FRN 40 - Screening for Methicillin-Resistant Staphylococcus aureus (MRSA): Future Research Needs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening_research.pdf
      June 01, 2013 - Routine clinical cultures may miss a large portion of patients who are silent carriers of these organisms … Routine clinical cultures may miss a large portion of patients who are silent carriers of these organisms … It may be harder to address rare outcomes such as infection rates using cluster RCTs because very large … Large numbers of exposure variables can be studied, but only one outcome variable can be studied at … o Large multicenter trials needed.

1417. Data Points 15: Breast Cancer Diagnostic Workup: Prognostic factor testing among older women with ductal carcinoma in situ and early invasive breast cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/dcis-prognostic-tests_research.pdf
      August 22, 2012 - Rates were highest among women with large tumors (68.8%) and those who received a mastectomy (63.6% … We found large increases in the use of ER/PR and HER2 testing between 2004 and 2007. … In both cases, reported testing points to large changes in clinical practice. … In addition to significant geographic and racial variation in testing, we found large increases in the

1418. Presentation of Future Research Needs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/presentations-future_research.pdf
      April 01, 2012 - It is possible that fields with a large evidence base are more amenable to focused prioritization efforts … members of the stakeholder panel on treatment for localized prostate cancer 9 took into account two large … Maybe: Large number of studies recently completed or ongoing in patients with other comorbidities … potential limitations Yes: Most efficient method for evaluating long-term outcomes given the large

1419. Nephropathy-Contrast-Induced Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_research-protocol.pdf
      October 01, 2013 - The two most recent large primary studies produced discrepant results concerning the impact of contrast … diverse studies if the effect sizes are similar, particularly when the power to detect variation is large … number of studies is small and could detect unimportant heterogeneity when the number of studies is large … Incidence of contrast-induced nephropathy with volume supplementation--insights from a large cohort.

1420. Community Forum Deliberative Methods Demonstration: Evaluating Effectiveness and Eliciting Public Views on Use of Evidence--Executive Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/deliberative-methods-demonstration-executive-131125.pdf
      November 01, 2013 - • Changes in participants’ empathy and concern for issues affecting the community at large. … • Concern for the welfare of the community at large arose when discussing evidence that unchecked … Numerous participants, who had been unaware of the government’s large role in paying for health care … In sum, large and consistent differences among groups on knowledge and attitude outcomes would have