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41. Bleeding Risks With Aspirin Use for Primary Prevention in Adults: A Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/j69Hq5ALvzg74e-ngkzSep
    April 01, 2016 - Some subgroup analyses (for example, proton- pump inhibitor or statin use) were not specified a priori … , 1.05 to 1.16]), with a possible protective effect on bleeding risk from proton-pump inhibitor and statin … 1.05–1.16) Aspirin (current vs. never) – – 1.61 (1.54–1.69) Any antihypertensive – – 1.14 (1.08–1.19) Statin

42. PII: S0749-3797(01)00255-0 (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/yw_rbA_nQrCnkaN8X5t56S
    January 01, 2001 - trials were published after 1995 and used hepatic 3-methylglutaryl coenzyme A reductase inhibitors or “statin … The two trials employing statin drugs (WOSCOPS and AFCAPS) had larger initial decreases in TC (20% and … Repeat analyses, using data from the two statin trials alone, produced slightly larger estimates of effect … Statin drugs have produced larger reductions in cholesterol and appear to reduce events more than the … Cholesterol lowering with statin drugs, risk of stroke, and total mortality: an overview of randomized

43. Archived: Evidence Summary: Lipid Disorders in Adults (Cholesterol, Dyslipidemia): Screening, 2001 | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening-2001
    April 09, 2001 - The two trials employing statin drugs (WOSCOPS and AFCAPS) had larger initial decreases in TC (20% and … Repeat analyses, using data from the two statin trials alone, produced slightly larger estimates of effect … 0.80; 95% CI=0.54 to 1.16) that did not reach statistical significance. 40 Another meta-analysis of statin … Statin drugs have produced larger reductions in cholesterol and appear to reduce events more than the … Cholesterol lowering with statin drugs, risk of stroke, and total mortality: an overview of randomized

44. Nontraditional Risk Factors in Cardiovascular Disease Risk Assessment: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/_nVeFxDCT9L-_cnDf_V3fK
    July 17, 2018 - CVD event (MI, CVA, hospitalization for unstable angina, revascularization, or CVD mortality) in the statin … 1 study, n = 1005 (RCT) St Francis Heart Study found no benefit for CAC-guided moderate-intensity statin … the context of the larger body of evidence on major bleeding from low-dose aspirin KQ5: hsCRP-Guided Statin … Statin use for the primary prevention of cardiovascular disease in adults: US Preventive Services Task … Implications of coronary artery calcium testing among statin candidates according to American College

45. Seventh Annual Report to Congress on High-Priority Evidence Gaps for Clinical Preventive Services | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/reports-congress/seventh-annual-report-congress-high-priority-evidence-gaps-clinical-preventive-services
    November 01, 2018 - Gynecologic Conditions With Pelvic Examination Vision Screening in Children Younger Than Age 3 Years Statin

46. Information for Consumers | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation-topics/information-for-consumers
    Centers for Disease Prevention and Control Guide Statin

47. Archived: Final Evidence Summary: Lipid Disorders in Children: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary34/lipid-disorders-in-children-screening-2007
    July 15, 2007 - All the trials of statin drugs, 18 , 19 , 165 , 169 , 172 , 173 , 179 , 184 , 188 demonstrated improvement … Efficacy and safety of statin therapy in children with familial hypercholesterolemia: a randomized controlled … Various statins 22 professional athletes, 15-27 y 8 y Muscle pain reported in 84% of periods of statin … Statin drugs were associated primarily with elevations in LFTs and CK.

48. Archived: Coronary Heart Disease: Screening Using Non-Traditional Risk Factors | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/coronary-heart-disease-screening-using-non-traditional-risk-factors-2009
    October 15, 2009 - C-reactive protein levels and outcomes after statin therapy. N Engl J Med 2005;352:20-8.

49. Archived: Final Research Plan: Carotid Artery Stenosis: Screening, December 2007 | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan36/carotid-artery-stenosis-screening-december-2007
    January 23, 2014 - Share to Facebook Share to X Share to WhatsApp Share to Email Print archived Final Research Plan Carotid Artery Stenosis: Screening, December 2007 January 23, 2014 Recommendations made by the USPSTF are independent of the U.S. government. T…

50. Archived: Final Research Plan: Carotid Artery Stenosis: Screening, December 2007 | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/ResearchPlanFinal/carotid-artery-stenosis-screening-december-2007
    January 23, 2014 - Share to Facebook Share to X Share to WhatsApp Share to Email Print archived Final Research Plan Carotid Artery Stenosis: Screening, December 2007 January 23, 2014 Recommendations made by the USPSTF are independent of the U.S. government. T…

51. Recommendation: Asymptomatic Carotid Artery Stenosis: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/carotid-artery-stenosis-screening
    February 02, 2021 - cardiovascular risk factors Aspirin use to prevent cardiovascular disease and colorectal cancer Statin … cardiovascular risk factors 14 Aspirin use to prevent cardiovascular disease and colorectal cancer 15 Statin … Statin use for the primary prevention of cardiovascular disease in adults: US Preventive Services Task

52. Final Research Plan: Asymptomatic Carotid Artery Stenosis: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/carotid-artery-stenosis-screening
    November 14, 2019 - Share to Facebook Share to X Share to WhatsApp Share to Email Print Final Research Plan Asymptomatic Carotid Artery Stenosis: Screening November 14, 2019 Recommendations made by the USPSTF are independent of the U.S. government. They should no…

53. USPSTF Clinician Summary of USPSTF Recommendation: Screening for Lipid Disorders in Children and Adolescents (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/SkbkgyTc826aqUmKghKELw
    July 01, 2023 - USPSTF Clinician Summary of USPSTF Recommendation: Screening for Lipid Disorders in Children and Adolescents USPSTF Clinician Summary of USPSTF Recommendation Screening for Lipid Disorders in Children and Adolescents July 2023 What does the USPSTF recommend?…

54. A and B Recommendations | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation-topics/uspstf-a-and-b-recommendations
    June 01, 2025 - B March 2018 * Statin Use for the Primary Prevention of Cardiovascular Disease in Adults … cardiovascular disease (cvd) risk of 10% or greater The USPSTF recommends that clinicians prescribe a statin

55. Final Research Plan: Lipid Disorders in Children and Adolescents: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/lipid-disorders-in-children-screening
    August 19, 2021 - What is the optimal timing of statin treatment initiation for FH?

56. Screening for Lipid Disorders in Children: Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/BwAo_shwmJLSRguyWxaXpP
    July 01, 2007 - *Benefits of detection and early treatment: Trials of statin drugs in children with monogenic dyslipidemia

57. Screening for Asymptomatic Carotid Artery Stenosis: US Preventive Services Task Force Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/e6_WqcwDGhgT6bQfmk3Hqj
    February 02, 2021 - cardiovascular risk factors • Aspirin use to prevent cardiovascular disease and colorectal cancer • Statin … cardiovascular risk factors14 • Aspirin use to prevent cardiovascular disease and colorectal cancer15 • Statin … Statin use Clinical Review & Education US Preventive Services Task Force USPSTF Recommendation: Screening

58. Evidence Summary: Aspirin Use to Prevent Cardiovascular Disease: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/aspirin-to-prevent-cardiovascular-disease-preventive-medication
    April 26, 2022 - fully conducted prior to 2001, when Adult Treatment Panel III (ATP III) guidelines were published and statin … RCTs that were partly or fully conducted prior to 2001 (when the ATP III guidelines led to widespread statin … Contemporary CVD risk factor management, especially widespread statin use, may alter the relative importance … Aspirin to Reduce Risk of Initial Vascular Events (ARRIVE), and ASPREE—performed subgroup analyses by statin … Age-related trajectories of cardiovascular risk and use of aspirin and statin among US adults aged 50

59. Archived: Lipid Disorders in Children: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/lipid-disorders-in-children-screening-2007
    July 15, 2007 - Benefits of detection and early intervention: a Trials of statin drugs in children with monogenic dyslipidemia

60. Using Nontraditional Risk Factors in Coronary Heart Disease Risk Assessment: U.S. Preventive Services Task Force Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/gXnmnkofo8FxoLnCmXJDjb
    October 01, 2009 - C-reactive protein levels and outcomes after statin therapy. N Engl J Med. 2005;352:20-8.