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cds.ahrq.gov/taxonomy/term/147901
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cds.ahrq.gov/taxonomy/term/147891
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www.ahrq.gov/sites/default/files/wysiwyg/evidencenow/results/research/cholesterol-narrative.pdf
December 31, 2018 - Statin Therapy Measure Narative
Statin Therapy for the Prevention and Treatment of Cardiovascular Disease … diabetes with a fasting or direct LDL-C level of 70-189
mg/dL; who were prescribed or are already on statin … Numerator
The number of patients with a statin medication (Statin RXNORM Value Set) current on the … medication
list or prescribed a statin medication during the measurement period. … Denominator Exceptions
• Patients with adverse effect, allergy or intolerance to statin medication
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cds.ahrq.gov/cdsconnect/keywords/statin-therapy
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www.ahrq.gov/sites/default/files/wysiwyg/evidencenow/results/research/cholesterol-flowchart.pdf
June 02, 2025 - Statin Therapy Measure Flow Chart
Statin Therapy for the
Prevention and Treatment of
Cardiovascular … Disease
Yes
*Contraindications and Exceptions to Statin Use
· Patients with adverse effect, allergy … or
intolerance to statin medication therapy
· Patients who are pregnant or breastfeeding
· Patients … e
Yes
PATIENT
INCLUDED IN
DENOMINATOR
1
Was the patient
prescribed or on a statin
at any … No
PATIENT NOT
INCLUDED IN
NUMERATOR 3
11_18_2015 Statin Therapy Measure Flow Chart 3 Denom v3.
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www.ahrq.gov/sites/default/files/wysiwyg/evidencenow/results/research/chart-abstraction-template-cholesterol.xlsx
November 18, 2015 - Cholestrol Control with Statin Therapy
CHOL
PCP Demographics
Demographics DOB 40-75 (DM),
≥ 21 … Statin Med
No statin then check LDL, if yes in Num. … Statin Med
No statin then check LDL, if yes in Num. <70
If < 70 exempt,
≥70 statin required and failed … Fluvastatin Lescol XL or Lescol Statin
Lovastatin (Mevinolin) Mevacor or Altoprev Statin
Pitavastatin … Livalo N/A
Pravastatin Sodium Pravachol Statin
Rosuvastatin Calcium Crestor Statin
Simvastatin Zocor
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www.ahrq.gov/sites/default/files/wysiwyg/evidencenow/heart-health/strategies-to-better-manage-lipids.pptx
November 01, 2016 - Strategies to Better Manage Lipids – Statin Pearls
Strategies to Better Manage Lipids – Statin Pearls … Measures – Cholesterol
Percentage of “high-risk” adult patients who were prescribed or are taking a statin … (CVD) (i.e., symptomatic coronary artery disease or thrombotic stroke)
use a low- to moderate-dose statin … Clinicians may choose to offer a low- to moderate dose statin to certain adults without a history of … Other side effects – try a 6 week break and then restarting
Add Co-enzyme Q10
Stop statin and focus
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cds.ahrq.gov/sites/default/files/cds/artifact/1056/2024_Intervention_Content_Statin_Patient_1.xlsx
January 01, 2024 - Example Intervention Text
Example Patient-Facing Intervention Text: Statin Use for the Primary Prevention … example intervention text shown below is embedded in the Clinical Quality Language (CQL) files for the Statin … Statin Use for the Primary Prevention of CVD in Adults: Patient-Facing CDS Intervention Text
DISPLAY … or older and have one or more risk factors for CVD, you should consider taking a medication called a statin … It lists questions to ask the doctor about personal risk as well as about taking a statin.
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www.ahrq.gov/data/infographics/statin-use.html
August 01, 2018 - Statin Use in U.S. Adults Doubles
Statin Use in U.S. … Adults Doubles (PDF, 263 KB)
Source: Statistical Brief #458: Trends in Statin Therapy among Adults … (Age ≥ 18), United States, 2000 to 2011 ; Statistical Brief #459: Changes in Statin Therapy among Adults
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effectivehealthcare.ahrq.gov/health-topics/statins
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cds.ahrq.gov/sites/default/files/cds/artifact/1056/2024_Data_Requirements_Statin_CVD_Patient_Facing.xlsx
January 01, 2024 - FHIR DSTU2 Data Requirements
FHIR DSTU2 Data Requirements: Statin Use for the Primary Prevention of … valueCodeableConcept Mixed (1 single code and 1 VS) 72166-2 (question) 2.16.840.1.113883.3.600.2390 (response)
Statin … 2.16.840.1.113883.3.526.3.1575
2.16.840.1.113762.1.4.1032.17 2.16.840.1.113883.3.526.3.1572
2.16.840.1.113762.1.4.1032.18
Statin … 2.16.840.1.113883.3.526.3.1572
2.16.840.1.113762.1.4.1032.18
FHIR R4 Data Requirements
FHIR R4 Data Requirements: Statin … valueCodeableConcept Mixed (1 single code and 1 VS) 72166-2 (question) 2.16.840.1.113883.3.600.2390 (response)
Statin
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6dqHx6xQGq9GUv92rZUf2q
August 01, 2022 - Statin Use for the Primary Prevention of Cardiovascular Disease in Adults
The USPSTF recognizes … Clinician Summary of USPSTF Recommendation
Statin Use for the Primary Prevention of Cardiovascular … smoking) and an estimated 10-year cardiovascular disease (CVD) risk of
10% or greater: Initiate a statin … is smaller, so clinicians should selectively offer a statin, taking patient values
and preferences … • To achieve the full benefits of statin use, it is essential to equitably improve statin use in
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www.ahrq.gov/sites/default/files/wysiwyg/data/infographics/statin-use.pdf
June 03, 2015 - Statin Use in U.S. … Adults Doubles in 10 Years
Source: MEPS Statistical Brief #458: Trends in Statin Therapy among Adults … Branded Statin
2010-
2011
2008-
2009
2006-
2007
2004-
2005
2002-
2003
2000-
2001
Average Annual … In the 10-year period
ending in 2011, statin use roughly doubled among all adult age groups. … Statin Use in U.S. Adults Doubles in 10 Years
Publication Date: June 3, 2015
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www.ahrq.gov/sites/default/files/2024-01/strom-report.pdf
January 01, 2024 - The I*R represents the relative effect of each statin type (statin 3A4 substrate vs. statin non-3A4 … for each CYP3A4 inhibitor evaluated by statin
type (statin 3A4 substrate and statin non-3A4 substrate … Baseline characteristics Statin 3A4
substrate
Statin non-
3A4 substrate
Statin 3A4
substrate
Statin … non-
3A4 substrate
Statin 3A4
substrate
Statin non-
3A4 substrate
# of statin initiators 325,460 … )
0.90
(0.53-1.52)
statin 3A4 substrate 2358 657,276 3.59
statin non-3A4 substrate + CYP3A4X
statin
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www.ahrq.gov/sites/default/files/wysiwyg/data/SyH-DR-stat-brief-4-statins.pdf
October 01, 2024 - Statin Use by Region
Among those hospitalized for IS/TIA, overall statin use was lower inside the stroke … Variability in Statin Use in Medicare 4
Figure 2. … Use in Medicare 5
Statin Use by State
Figures 4-6 display overall and state-level statin use rates … statin
prescription fills during the 3 months after hospital discharge (“any statin use”) from a
cardiovascular … Use
Statin Use by Region
Statin Use by State
Data Source
Definitions
Use of Statins
Statin Prescription
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www.ahrq.gov/sites/default/files/wysiwyg/data/data-innovations-statbrief-statins-commercial-insurance.pdf
October 02, 2024 - Statin use was lower inside the stroke
belt for both sex and age categories. … Variability in Statin Use in Commercially Insured Beneficiaries 3
Figure 2. … Variability in Statin Use in Commercially Insured Beneficiaries 6
Figure5. … Statin Prescription Fills
We examine the percentage of adults ages 45-64 with any outpatient statin … Variability in Statin Use in Commercially Insured Beneficiaries 9
Table 1.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication
August 23, 2022 - To achieve the full benefits of statin use, it is essential to equitably improve statin use in both women … Treatment and Statin Intensity
There are limited data directly comparing the effects of different statin … or by titration of statin therapy to a target LDL-C level vs use of a fixed statin dose. … therapy or based on statin intensity. … and mortality
Harms of statin use
Convincing evidence that the harms of statin use in
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/vTJ_Zj3TAkhx45wWUDtNyt
May 01, 2021 - Treatment and Statin Intensity
There are limited data directly comparing the effects of different statin … Summary of USPSTF Rationale
Rationale Assessment
Benefits of statin use • Convincing evidence that statin … Harms of statin use • Convincing evidence that the harms of statin use in adults aged 40 to 75 years … , or by titration of statin
therapy to a target LDL-C level vs use of a fixed statin dose. … therapy or based on statin intensity.
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/statin-use-in-adults-preventive-medication
August 23, 2022 - Treatment and Statin Intensity
There are limited data directly comparing the effects of different statin … statin use 15 compared with White adults. … or by titration of statin therapy to a target LDL-C level vs use of a fixed statin dose. … therapy or based on statin intensity. … and mortality
Harms of statin use
Convincing evidence that the harms of statin use in
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/JcwfLrEqaaxP6DPEQvxgUs
February 18, 2020 - statin use in adults aged 40 to 75 years are small. … The majority (>80%) use a statin alone.29 The
Table. … Statin Regimens Used in Available Trials
Statin
Dose, mga
Low Moderate High
Atorvastatin 10-20 40- … There are limited data on different
statin dosing strategies; trials that directly compare titrated statin … Harms of Statin Use
In randomized trials of statin use for the primary prevention of
CVD, statin therapy