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241. Allocation of Scarce Resources During Pandemics: Strategies for Policy Makers | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/allocation-scarce-resources/protocol
     April 01, 2020 - The affected population includes people who require medical or psychological treatment.

242. AHRQ EPC Pilot Projects Summary: Improving Health Systems' Access to High Quality Evidence | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/health-systems-access-evidence/overview
     January 01, 2020 - Companion products can augment reports to improve usefulness, but require additional time and resources

243. Pain Management Interventions for Elderly Patients With Hip Fracture | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/hip-fracture-pain/clinician
     December 01, 2019 - For example, treatment of moderate to severe pain may require opioids, which present complications that

244. Methods Research Report Improving Access To And Usability of Systematic Review Data for Health Systems Guideline Development (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-health-systems-guidelines-development.pdf
     February 01, 2019 - level of expertise of the end users, as those with more or less familiarity with a set of data may require … Tools would need to be relatively intuitive and not require a significant amount of training in order … This inherently excluded any tool that was not “off the shelf” and would require significant development … However, any changes to the design of the workbook would require additional data manipulation by a staff … level of expertise of the end users, as those with more or less familiarity with a set of data may require

245. PICO #1 Population(s): Children with infantile hemangiomas (IHs) Intervention(s): Early referral Comparator(s): Delayed referral Outcomes(s): Minimization of functional impairment and/or cosmetic deformity PICO #2 Population(s): Children… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/pico-1-populations-children-with-infantile-hemangiomas-ihs-interventions-early-referral-comparators-delayed-referral-outcomess-minimization-of-functional-impairment-andor-cosmetic-deformity-pico-2-populations-children-with
     November 01, 2017 - There is currently no algorithm to aid clinicians in determining which IH lesions require specialist

246. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 - If organizational policies require permission to adapt or use these materials, AHRQ will provide such … Different topics may require different decisions regarding NRSI inclusion. … The analysis, synthesis, and reporting of NRSIs also require special attention. … The current guidance therefore does not require that all SRs follow the same decision pathway. … Different topics may require different decisions regarding NRSI inclusion Another challenge worth

247. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 - If organizational policies require permission to adapt or use these materials, AHRQ will provide such … Different topics may require different decisions regarding NRSI inclusion. … The analysis, synthesis, and reporting of NRSIs also require special attention. … The current guidance therefore does not require that all SRs follow the same decision pathway. … Different topics may require different decisions regarding NRSI inclusion Another challenge worth

248. Non-Pharmacologic Interventions for Treatment-resistant Depression in Adults — Research Protocol Document | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/treatment-resistant-depression/research-protocol
     March 01, 2020 - New treatments without a current evidence that require further research, such as Magnetic Seizure Therapy … Magnetic Therapy (rTMS): focal magnetic stimulation through the scalp to produce a seizure, does not require

249. Chapter 11: Challenges in and Principles for Conducting Systematic Reviews of Genetic Tests Used as Predictive Indicators | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-genetic/methods
     December 01, 2019 - CLIA does not require clinical validation and many LDTs have had no clinical validation or clinical utility … questions 4, 9, 10, 24, 25, 38, 39, 42, 43, and 44) are relevant only for evaluating genetic tests or may require … Laboratory-developed tests do not require FDA clearance, and there is no requirement for publicly available … For example, some tests require visual inspection of electrophoresis gels.

250. Executive Summary_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2024 Update of the Evidence Base for the PTSD Trials Standardized Data Repository (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ptsd-5-final-report-update-2024-executive-summ.pdf
     January 01, 2024 - updated eligibility criteria, to include self-help or internet-based interventions (those that do not require

251. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-biopsy-executive.pdf
     December 01, 2009 - Generally, only malignant lesions require invasive followup procedures such as surgical excision or lymph … above, the majority of women who are sent for breast biopsy do not have malignant lesions and do not require … type of breast biopsy procedure Bleeding severe enough Low 0.72% of core-needle procedures were to require

252. S96 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/s96.pdf
     October 01, 2007 - Data collection does not require additional work by clinical staff and has been well accepted by participating … collected, man- aged, analyzed, and interpreted under public health surveil- lance authority and do not require … NEISS-CADES may be biased toward collecting ADEs that have acute and life-threatening consequences which require

253. S89 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/s89.pdf
     October 01, 2007 - associated with vac- cines or drugs are often nearly impossible to detect in prelicen- sure studies and require … NC indicates not calculable because it would require dividing a number by zero. … defined may lead to dampening of true signals, whereas outcomes with insidious onset are likely to require

254. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive.pdf
     October 01, 2006 - reconstruction is generally used only for patients with complicated renal artery anatomy or for patients who require … interest that the CORAL trial may be able to evaluate, primarily through post hoc analyses, but that may require … This may require quality improvement and other types of studies.

255. Disposition of Comments Report for Local Hepatic Therapies for Metastases to the Liver From Unresectable Colorectal Cancer (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_disposition-comments.pdf
     December 11, 2012 - liver directed therapies are considered devices even though they are therapeutic in use), do not require … Under this system devices do not require the same level of evidence as is required for drug approval … companies can invest billions in a new drug, expecting many years of patent protection, and do not require … Under this system devices do not require the same level of evidence as is required for drug approval

256. Psoriasis-Chronic Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
     November 01, 2012 - skin may be managed effectively with topical agents, patients with more widespread disease often require … lipid profile may surface in the shorter term, while others such as malignancy and infection would require … toxicity associated with methotrexate or nephrotoxicity associated with cyclosporine, and would also require … Doing so would likely require longer duration trials and larger sample sizes as compared with the current

257. Methods Guide for Medical Test Reviews Chapter 11 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-genetic_methods.pdf
     July 01, 2012 - CLIA does not require clinical validation and many LDTs have had no clinical validation or clinical … questions 4, 9, 10, 24, 25, 38, 39, 42, 43, and 44) are relevant only for evaluating genetic tests or may require … Laboratory-developed tests do not require FDA clearance, and there is no requirement for publicly available … For example, some tests require visual inspection of electrophoresis gels.

258. Lower Limb Prosthesis | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/prosthesis/research-protocol
     January 01, 2019 - In addition, patients may require multiple LLPs (initial, preparatory, definitive, or replacement prosthetics … Medicare reimbursement policies require documentation of current functional capabilities and expected … who are being evaluated for or already have a lower limb prosthesis (LLP) Lower limb amputees who require

259. Routine Preoperative Testing: Comparative Effectiveness Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/preoperative-testing/research-protocol
     December 01, 2019 - review will not evaluate questions that are important and related to the topic at hand but that would require … To systematically review test performance would require a broader review of each test--beyond routine … abdominal, and pelvic surgeries) Exclude patients undergoing nonsurgical diagnostic procedures that may require

260. Cancer Quality-ASSIST Supportive Oncology Quality Indicator Set: Feasibility, Reliability, and Validity Testing | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/cancer-quality-indicator-testing/research
     January 01, 2020 - because either the data elements were not routinely in the medical record or we concluded that they would require … although much of the detailed clinical information in EMRs remains in free text fields which still require … Some types of indicators difficult to operationalize in this study, such as symptom followup, may require