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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
    November 01, 2014 - intensive care unit (ICU).1 Almost one-third of HAP episodes are acquired in ICUs;3 as many as 90 percent … of ICU cases may be ventilator associated.3,4 In the ICU setting, HAP accounts for up to 25 percent … of all infections and for more than 50 percent of the antibiotics prescribed.1 Guidelines issued … of care; in one report from Asian countries, they were associated with death rates of between 27 percent … and 50 percent.2 Patients who have received mechanical ventilation are at the greatest risk for HAP
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/telehealth_disposition-comments.pdf
    June 30, 2016 - telehome monitoring at the Heart Institute has cut hospital readmission for heart failure by 54 percent … Vincent Health and facilitated by the Guide platform reduced hospital readmissions to 5 percent for … patients participating in the program - a 75 percent reduction compared to the control group {20 … percent), and to the national average {20 percent)." … Vincent's Hospital Reduces Readmissions by 75 percent with a Remote Patient Monitoring- Enabled Program
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research-2012.pdf
    January 01, 2012 - A recent review reported that only 19 percent of 104 comparative effectiveness studies of medications … (95% confidence interval, 50 to 79 percent) analyzed by intention-to-treat. 33 The absolute risk … For example, for a 45-year-old woman with her uterus and a 4 percent risk of invasive breast cancer … confidence that the effect is outside this range (half of which [2.5 percent] is above 1.00). … The contour lines show a 70 percent probability that the new treatment provides 10 percent survival
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-metaanalysis_methods.pdf
    July 01, 2012 - Sensitivity and 100 percent minus specificity pairs from the same study (obtained with different cut-offs … meta-analyses, differences in the estimates of summary sensitivity and specificity were rarely larger than 5 percent … are fixed at 80% and 97%, respectively, and prevalence of venous thromboembolism varies from 5 to 50 percent … Meta-Analysis Metric ≤3 Hours >3 Hours p-Value for the Comparison Across Subgroups Summary sensitivity (percent … ) 80 (64 to 90) 96 (85 to 99) 0.036 Summary specificity (percent) 97 (94 to 98) 97 (95 to 99) 0.56
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment_research-protocol.pdf
    September 29, 2011 - Most stable angina is a sign of significant CAD, defined angiographically as a stenosis with a 70 percent … diameter in at least one major epicardial artery segment or with a ≥ 50 percent diameter in the left … CABG has the advantages of greater durability (graft patency rates exceeding 90 percent at 10 years … authors acknowledge that among the study limitations was the preponderance of men that reached 85 percent … between the CABG and the stent groups. 25 Results by sex are provided, but women represented only 23 percent
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
    November 01, 2012 - Background Psoriasis is a common, chronic, autoimmune inflammatory skin disease affecting 2 to 3 percent … psoriasis phenotypes, chronic plaque psoriasis is the most frequent, accounting for all but 10 percent … change in DLQI at 16 weeks was greatest for patients who achieved at least a PASI improvement of 75 percent … while the mean change in DLQI was lowest for patients who achieved a PASI improvement of less than 25 percent … Based on these data, the changes in DLQI in patients achieving a PASI improvement of greater than 25 percent
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer-therapy_research-protocol.pdf
    November 28, 2012 - per 100,000 with a mortality rate of 4.0.2 Overall 5-year survival rates for HCC are lower than 10 percent … incidence rate of HCC among patients with hepatitis C-related cirrhosis is estimated to be between 2 and 8 percent … Treatments Although surgical resection is the preferred first-line treatment of HCC, approximately 80 percent … and an ECOG status ≤1  Involve an intervention of interest and  Does not contain more than 10 percent … However, we have allowed for 10 percent contamination of a study population for this review.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-urinary-retention_disposition-comments.pdf
    September 15, 2014 - evidence suggested no significant difference in the rate of UTI (diagnostic criteria not specified); 79 percent … therapy group and 88 percent of the successful TWOC between TURP group were catheter free at 6 months … ; 7 percent of the microwave therapy group and 4 percent of the TURP group maintained PVR volumes above … include urinary retention as an adverse event of Botulinum Toxin treatment affecting between 17 and 31 percent
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-protocol.pdf
    August 04, 2023 - intelligence (AI) feature of DistillerSR (AI Classifier Manager), such that we will re-review the top 30 percent … To accomplish this, after a single team member reviews each citation, we will re-review the top 30 percent … A second team member will review a randomly selected 10 percent sample of the articles to verify that
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-appendix-c-prepub-final.xlsx
    January 01, 2025 - Participants Age > 65 Years Number Participants Age < 50 Years Percent Participants Age < 50 Years Number … Females, Cases Percent Females, Controls Race/Ethnicity, N (%) Percent White White Comments PercentPercent Asian Asian Comments Percent Hispanic Hispanic Comments Percent Other Race/Ethnicity Other Race … Stage I Cancer Stage I Cancer Comments Number Stage II Cancer Percent Stage II Cancer Stage II … Stage IV Cancer Percent Stage IV Cancer Stage IV Cancer Comments Number Cancer Stage Missing Percent
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_disposition-comments.pdf
    August 01, 2012 - Based on NHANES data, prevalence of CKD stages 1-3 is 41.1 percent in patients with diabetes, 27.8 percent … in patients with hypertension, and 39.3 percent in those with cardiovascular disease. … This data indicated annual urinary microalbumin testing in about 30 percent of diabetics and 4 percent … This data indicated annual urinary microalbumin testing in about 30 percent of diabetics and 4 percent … This data indicated annual urinary microalbumin testing in about 30 percent of diabetics and 4 percent
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/field-triage-glascow-disposition-170415.pdf
    January 12, 2017 - distinguish patients who experience an outcome from those who do not based on a higher score is 1 percent … to 5 percent higher with the tGCS than with the more abbreviated scales. … TEP Reviewer #4 Clarity and Usability Table 2, page 21, percent sign missing from 6th row, 4th column … What about a study with 50 or 90 percent nontrauma –why exclude one with <10% nontrauma but not one … Should it maybe be “proportion WITH trauma was less than 10 percent”?
  13. effectivehealthcare.ahrq.gov/sites/default/files/study-size-planning-chapter-9.pptx
    January 01, 2013 - Use a conventional statistical significance cutoff of α = 0.05 and a standard required power of 80 percent … Many studies also use a standard required power of 80 percent, although other values are often considered
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-treatment_research-protocol.pdf
    November 08, 2011 - Estimates of the incidence of pressure ulcers vary according to the setting and range from 0.4 to 38.0 percent … in acute-care hospitals, from 2.2 to 23.9 percent in long-term nursing facilities, and from 0 to 17 … percent in the home-care setting. 1,2 Various systems have been used to assess the severity of pressure
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
    January 01, 2015 - Overall attrition in drug trials ranged from 4 percent in one off-label international trial65 to 47 … percent,3 with most studies having 30- to 40-percent overall attrition. … Only two off-label pharmaceutical trials reported overall attrition of less than 25 percent.64,65 Industry … funded 85 percent of the 17 drug trials that reported the source of study funding. … 31.6%), headache (19.6%), and dry mouth (19.1%) in the duloxetine-MDD group, which were 0.4 to 3.3 percent
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_executive.pdf
    July 01, 2013 - SAR afflicts approximately 10 percent of the U.S. … In allergen-specific immunotherapy trials, a minimum 30-percent greater improvement than placebo in … As shown, two sources (row 2 and row 4) converged around an MCID of 30-percent change in maximum TNSS … The concordance of these values increased our confidence that 30 percent of maximum score is a useful … This finding was based on studies of 20 percent of oral selective antihistamines and 9 percent of oral
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/menopause_research-protocol.pdf
    March 25, 2012 - During menopause, approximately 85 percent of women report experiencing symptoms of varying type and … early postmenopausal period the prevalence of vasomotor symptoms among women ranges from 30 to 80 percent … , depressed mood occurs in approximately one third, and sleep disturbance in more than 40 percent; … In 1995, an estimated 37 percent of women aged 50 years or older in the United States reported using … In the Study of Women’s Health Across the Nation,25 approximately 80 percent of participants reported
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccines-safety-protocol-130325.pdf
    September 18, 2012 - HPV is the most common sexually transmitted infection, affecting approximately 27 percent of U.S. women … - 18—the two strains covered by the HPV vaccine—are thought to be responsible for approximately 70 percent … substantial proportion of these cases of cervical cancer, completion of the three-dose series was only 34.8 percent … events that appear in at least three trials, a meta-analysis can estimate the odds ratio and its 95- percent
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-service_technical-brief.pdf
    January 01, 2012 - Of those 3.3 million, approximately 1.8 million were 65 years and older (5.2 percent of that population … of that population).1 A similar survey conducted in 2002 estimated use at 1.2 percent of the population … 15 years and older, 4.5 percent of the population 65 years and older, and 0.2 percent of the population … ) wheelchair users of all ages including 88,000 under age 18 years (0.12 percent) and 897,000 (2.87 … percent) 65 years of age and older.
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar_research.pdf
    August 01, 2015 - and is expected to increase to nearly 10 percent by 2050, at which time an estimated 39 million people … Type 1 diabetes, which accounts for 5 to 10 percent of all diabetes cases, is characterized by insulin … Consensus among stakeholders was pre-defined as agreement in responses of 50 percent or higher in three … and is expected to increase to nearly 10 percent by 2050, at which time an estimated 39 million people … Type 1 diabetes, which accounts for 5 to 10 percent of all diabetes cases, is characterized by insulin

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