-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_research-protocol.pdf
June 10, 2013 - reimbursements,
according to 2005 data from the Centers for Medicare and Medicaid Services (CMS).1 Up to 20
percent … Framingham Heart Study13 and the Olmsted
County Study.14 However, the death rate remains high: 50 percent … diagnosed with HF
die within 5 years after diagnosis.13,14 Among Medicare beneficiaries, more than 30 percent … An analysis of
2007 to 2009 Medicare claims data showed that 24.8 percent of beneficiaries admitted … , despite the
observation that HF hospitalizations in the United States have declined by almost 30 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
January 01, 2012 - Less
than half (11; 46 percent) of respondents were aware of the relevant Cochrane review when they … A survey of all 2,535 reviews published in the Cochrane Library in 2007 found that only 3.2
percent … stated explicitly that no more research was needed, whereas 82.0 percent of reviews
made suggestions … regarding the interventions that needed evaluating, 30.2 percent suggested the
appropriate participants … that needed studying, and 51.9 percent suggested the outcome
measures.11 However, it is unclear the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-treatment_research-protocol.pdf
September 30, 2010 - differences in definitions and sampled population subgroups.9 Recent studies have
reported that 25 percent … of young women,10 44 to 57 percent of middle-age and post-menopausal
women,11,12 and 75 percent of … The fraction of nursing home admissions attributable to UI in the elderly
women was 6 percent.14 At … treatment for UI who represent only a small proportion of adults with UI.21-24 Moreover, only 45
percent … of women with weekly UI episodes ever seek medical care.21 Primary care providers
diagnose UI in 21 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer-therapy_executive.pdf
May 01, 2013 - leading cause of cancer death worldwide.1
Overall 5-year survival rates for HCC are
less than 10 percent … rate of HCC
among patients with hepatitis C–related
cirrhosis is estimated to be between 2 and
8 percent … Thresholds for the interpretation of
I2 were: 0 percent to 40 percent, may not be important;
30 percent … to 60 percent, may represent moderate
heterogeneity; 50 percent to 90 percent, may represent
substantial … heterogeneity; 75 percent to 100 percent,
represents considerable heterogeneity.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
November 01, 2012 - Based on a
national survey of households,
approximately 1.6 percent of U.S. … adults over 20 years of age have
antibodies to HCV, indicating prior
acute HCV infection.1 About 78 percent … most common indication for liver
transplantation among American adults,
accounting for more than 30 percent … therapy with pegylated interferon plus ribavirin is
associated with higher SVR rates (about 55–60 percent … overall
in IDEAL), with an absolute difference of about 1 percent,
and adverse events with antiviral
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-199-skin-cancer.pdf
December 01, 2017 - Infections at the treatment
site were described in 5.5 percent of lesions with surgical
treatments … (95% CI 28 to 10.7) and were reported in less
than 1 percent for PDT and drugs. … Of note, the average
recurrence rate with drugs is 51.5 percent (95% CI 28.9 to
73.5), reflecting the … in the active treatments
and 88 percent with placebo, which is similar to the results
by individual … (95% CI, 3.4 to 40.5)
for drugs (F); it was less than 1.2 percent for other
intervention categories
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
January 01, 2015 - Most new interventions are
not adopted by 100 percent of the patient population with the disease or … to 3 percent of $3 trillion, using the lower and upper range of estimates. … However, even if
competition reduces oral HCV drug prices by 20 percent to 30 percent (e.g., to an estimated … for 75 percent of the overall estimated costs. … We will assume the
moderate figure of 25 percent market share for MarginProbe.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-gain-future_research.pdf
January 01, 2020 - to 34 percent and reduce the
prevalence of obesity among adults to less than 30 percent. … ES-5
Background
Context
The most recent estimates classify more than 35 percent of U.S. adults … to 34 percent and reduce the
prevalence of obesity among adults to less than 30 percent.5 Despite this … We selected comparisons identified by more than 50 percent of
stakeholders as high-priority comparisons … In Table 14, we present the study design,
methods, and reporting elements that at least 50 percent of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_executive.pdf
December 01, 2015 - PSQI scores decreased
by over 35 percent from baseline with CBT-I and by less
than 10 percent with … , compared with
42 percent taking placebo. … Study withdrawal for any
reason occurred in 58 percent of older adults. … The rate of remission or response ranged from 50 to
80 percent in CBT-I groups and from 0 to 50 percent … Remitter or response rate ranged
from 50 to 85 percent in the treatment groups and from
19 to 48 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
January 01, 2018 - percentages of
young people filling prescriptions for
antipsychotics in the United States was
0.11 percent … (younger children), 0.8
percent (older children) 1.19 percent
(adolescents), and 0.84 percent (young … Off-label use of
antipsychotics is common in children and adults.1,12
Twenty-four to 31 percent of … For subjective outcomes in trials, the overall ROB was
rated as high for 60 percent of studies; only … Seventy-
one percent of studies had short-term treatment durations.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-nursing-home-characteristics_research-protocol.pdf
November 03, 2011 - Although about 70 percent of people with dementia are cared for at home, many families
decide to place … Estimates from various studies indicate that
45 to 67 percent of residents of RC/AL residences have … In June 2008, 47 percent of all
NH residents had a diagnosis of dementia in their NH records.
1
NH … Given that almost half of NH residents have dementia, and only 5
percent of NH beds are in Alzheimer … in 2001 to 10.1 percent in 2007.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bladder-cancer-non-muscle-invasive_research-protocol.pdf
July 21, 2014 - 4,390 women).1 The lifetime probability of developing bladder cancer in
the U.S. is approximately 3.8 percent … in men and 1.2 percent in women, although the
incidence of bladder cancer is increasing in women. … Approximately 75 percent of
newly diagnosed bladder cancers are Non-MIBC.6 Individuals with Non-MIBC … .7 As many as 70 percent of Non-MIBC tumors will
recur after initial treatment, with a 10-20 percent … patients with more invasive Stage 2 or higher bladder cancers (5-
year survival rates from 63 to 15 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-update_research-protocol.pdf
June 06, 2017 - About 17 percent of
nonpregnant, adult women have experienced UI.2 The prevalence of UI increases with … age, particularly after menopause; about 3.5 percent of women aged 20 to 29 years old
have experienced … UI, 22 percent of women aged 50 to 59 years old, and 38 percent of
women over age 80.2 The prevalence … In addition, we will apply stricter rules about the exclusion criteria, allowing only up to
10 percent … If we find studies
that were included in the 2012 AHRQ review that included between 10 and 25 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-agitation-aggression_research-protocol.pdf
November 13, 2014 - million people provide unpaid
caregiving.2 Dementia primarily affects older adults; approximately 14 percent … that managing behavioral symptoms in the community
increased the cost of informal caregiving by 25 percent … and formal care by 35 percent. … Up to 90 percent of those with dementia will at some stage exhibit behavioral or
psychological symptoms … .11-13 These symptoms also challenge staff in
long-term care (LTC) facilities where an estimated 80 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_executive.pdf
November 01, 2012 - Medicaid finances 40 percent of total
national LTC spending.9
Almost 1.4 million individuals currently … In 2009, NH
expenditures accounted for about 64 percent of Medicaid
LTC expenditures for older adults … to
43 percent.13 Within Medicaid, spending for HCBS varies
among different populations. … In 2009, HCBS expenditures
made up about 36 percent of LTC expenditures for older
adults and people … of
LTC spending, and private LTC insurance makes up about
9 percent.9
Both NHs and HCBS may offer
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/alcohol-pharma-final-protocol.pdf
January 01, 2023 - version 5
(DSM-5) criteria for an alcohol-use disorder (AUD) in the past year.2 Of those, only
about 7 percent … reported receiving treatment of any type, with 4 percent prescribed a U.S. … Some studies indicate that less than 10 percent of those with
AUDs are able to achieve long periods … They found that whereas, in aggregate,
about 25 percent of individuals maintained sobriety over 1 year … of individuals who met criteria for an
AUD reported receiving treatment of any type, with 4 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_executive.pdf
June 01, 2013 - Thus, the reported rate of mortality was
0.48 percent for LAGB and 0.0 percent for gastric sleeve, … Only two studies followed patients for more than 2 years;
one has a followup rate of only 13.8 percent … Additionally, in 76 percent
of instances, only a single study contributed data to a
particular adverse … Outcomes at 12 to
24 months were reported for only a small number of
patients (6.8 percent) presumably … Biliopancreatic diversion with duodenal switch (BPD):
Surgery that involves removing 70 percent of the
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-outcome-measure-harmonization-depression.pdf
November 01, 2020 - score > 9 who demonstrates
a response to treatment defined as a PHQ-9 score that is reduced by 50
percent … months’ duration and subsequently experiences a recurrence
of a depressive episode, defined as a 50 percent … A 2015 review of EHR data from primary care practices
found that only 3 percent of patients with documentation … of suicide ideation in unstructured
clinical notes had a corresponding ICD-9 code, and only 5 percent … For suicide attempt, 19
percent of patients with a suicide attempt documented in the notes had a corresponding
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-protocol-update-2023.pdf
January 01, 2023 - , quality of life, and healthcare utilization.1 Lifetime prevalence of PTSD is estimated to be
six percent … in American civilians2,3 and seven to nine percent in Veterans.4,5 Since PTSD was first
included by … columns focused on
documenting the analysis type (e.g., intent to treat, per protocol), the overall percent … missing
primary PTSD outcome assessment data (i.e., overall attrition from measurement), and the
percent … Duration of PTSD symptoms/diagnosis
5. % Active Duty Military
6. % Veteran Percent
7. % Service-Connected
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
January 01, 2016 - is contrast-induced
nephropathy (CIN), defined as an increase
in serum creatinine of more than 25
percent … A body of evidence was assessed as having high study
limitations if greater than 50 percent of the studies … 0.1 probability of CIN in the comparison
group and a minimally important relative difference of
25 percent … expected 0.02 probability in the comparison group and a
minimally important relative difference of 25 percent … point estimate of this reduction did not exceed a minimally
important relative risk difference of 25 percent