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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_research-protocol.pdf
    January 27, 2012 - AUDs is higher for men than for women, with estimates indicating a lifetime risk of more than 20 percent … for men.12,14-16 Alcohol dependence has lifetime prevalence rates of about 17 percent for men and 8 … percent for women.17 AUDs cause substantial morbidity and mortality—that is, threefold to fourfold … Using complete abstinence as an outcome, from 15 to 35 percent of patients have been reported to achieve … They found that whereas, in aggregate, about 25 percent of individuals maintained sobriety over 1 year
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
    May 15, 2017 - Epidemiology Rheumatoid arthritis (RA), an autoimmune systemic inflammatory arthritis condition, affects 1 percent … Over 35 percent of patients with RA have work disability after 10 years.11 The life span of patients … We will include studies with mixed populations if more than 50 percent of the study populations had … might not be important, 30 percent to 60 percent may represent moderate heterogeneity, 50 percent … to 90 percent may represent substantial heterogeneity, and 75 percent or greater represents considerable
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/trauma-child-interventions_research-protocol.pdf
    March 26, 2012 - However, only 0.5 percent of these trauma-exposed children met the full criteria for PTSD.1 In a survey … of adolescents 12 to 17 years of age, the 6-month prevalence for PTSD was 6.3 percent in girls and … 3.7 percent in boys.3 The prevalence of PTSD in younger children is largely unknown; however, several … One longitudinal study reported that 25 percent of its sample was exposed to or victimized by violence … (excluding sexual trauma), 11 percent was exposed to sexual trauma, and 32 percent was exposed to other
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
    February 01, 2013 - age, sex, race), comorbiditiy (such as diabetes, hypertension), clinical characteristic (such as percent … When necessary, we arbitrarily assumed a 50 percent correlation (r=0.5) between baseline and final values … Both observational studies reported net changes in minimal lumen diameter (MLD) and percent diameter … At medium term, meta-analysis of six RCTs revealed a significant 29 percent lower risk of restenosis … Meta-analysis of six RCTs, enrolling almost 1,800 patients, found a significantly 30 percent lower risk
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/protocol-pharm-pregnant-women_0.pdf
    December 05, 2018 - Background and Objectives for the Systematic Review According to Census data, 86 percent of women in … Medicaid claims data from 2000 to 2007 show that 8.1 percent of women were exposed to an antidepressant … ; from 2007 to 2010, the rate increased to 14.8 percent.18 Use of other psychotropic medications during … From 2001 to 2007, use of atypical antipsychotics by pregnant women more than doubled, from 0.3 percent … to 0.8 percent;19 use of antiepileptic drugs increased from 1.57 percent of deliveries to 2.19 percent
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
    August 01, 2013 - The estimated prevalence of AF is 0.4 percent to 1 percent in the general adult population,2,3 occurring … The prevalence increases to about 6 percent in people age 65 or older and to 10 percent in people age … in patients with a CHADS 2 score of 0 to 18.2 percent in patients with a CHADS 2 score of 6. … Male sex ranged from 44 percent to 84 percent in the included studies. … The proportion of male patients ranged from approximately 40 to 60 percent.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
    February 01, 2013 - , specificity 68 percent; ECHO (14 studies): sensitivity 79 percent, specificity 83 percent; SPECT ( … 14 studies): sensitivity 81 percent, specificity 78 percent; CMR (5 studies): sensitivity 72 percent … , specificity 84 percent; and CTA (5 studies): sensitivity 94 percent, specificity 87 percent. … , specificity 68 percent; ECHO (14 studies): sensitivity 79 percent, specificity 83 percent; SPECT ( … , specificity 84 percent; and CTA (5 studies): sensitivity 94 percent, specificity 87 percent.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-nonopioid-pharm-chronic-pain.pdf
    April 01, 2022 - The machine learning classifier was previously shown to have 100 percent recall for identifying eligible … All patients in the trial were pretreated with 4 percent lidocaine cream.6 There was no evidence on … There were also no differences between pregabalin formulations on DPRS 30 and 50 percent pain reduction … or more pain improvement (47.5% vs. 32.7%, p=0.004) and 50 percent or more pain improvement (27.2% … In this 10 RCT, a 5 percent lidocaine patch with 4 percent lidocaine cream premedication was not
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_executive.pdf
    January 01, 2010 - The prevalence of asthma in the United States is approximately 9 percent, and approximately 62 percent … Forty-eight percent of subcutaneous studies and 61 percent of sublingual studies had industry support … Local reactions, reported in 5 percent to 58 percent of patients and 0.6 percent to 54 percent of … We chose to consider a less than 15 percent difference as a weak magnitude of effect, a 15 percent … to 40 percent difference as a moderate magnitude of effect, and a greater than 40 percent difference
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
    June 01, 2012 - , and the solid red line indicates the true sensitivity of the index test, which is set at 70 percent … OSA has a prevalence of 2 to 4 percent in middle-aged adults. … The 95-percent limits of agreement are very wide in most studies, suggesting great variability in the … An important part of this type of analysis is the range of values defined by the 95-percent limits of … This is the area were 95 percent of the differences are thought to fall.
  11. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-options-summarizing.ppt
    June 01, 2012 - , and the solid red line indicates the true sensitivity of the index test, which is set at 70 percent … OSA has a prevalence of 2 to 4 percent in middle-aged adults. … The 95-percent limits of agreement are very wide in most studies, suggesting great variability in the … An important part of this type of analysis is the range of values defined by the 95-percent limits of … This is the area were 95 percent of the differences are thought to fall.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/choice-of-mean_white-paper.pdf
    April 01, 2015 - change and 1 (1.4%) used both MD and percent change. … The Knapp-Hartung modification (KH) produced narrower 95 percent CIs compared to the PE method, but … wider 95 percent CIs than others. … Estimates from PE method are not available in many cases, and the 95 percent CIs of PE method, when … smaller on average, ranging from 5 percent to more than 40 percent.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
    May 01, 2015 - studies of infants, children, and adults reported rates of ankyloglossia ranging from 0.1 to 10.7 percent … In infants with anterior or posterior ankyloglossia, there is a reported 25- to 80-percent incidence … of frenotomized infants had improved feeding within 48 hours, compared with 3 percent in the control … Outcomes that failed to show a difference in these two RCTs included percent improvement (50% vs. 40% … had major problems with dribbling and 71 percent had “excess wind” (gas).
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_executive.pdf
    September 22, 2011 - with 56 percent (56/102) of those using a standard retail pharmacy. … in the supervised DOT treatment, compared with 33 percent (8/24) using self-administered treatment … Patients in the intervention groups had approximately 50-percent higher odds of adhering to therapy … recommended course of treatment, compared with 75.0 percent of patients receiving placebo, although … In the RCT by Ramsey and colleagues,36 50 percent of the CBT-intervention group were considered to be
  15. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-2005_executive.pdf
    January 01, 2005 - In the studies reviewed for this report, from 10 percent to 65 percent of surgical patients still required … Almost 90 percent of patients who were followed for 5 or more years in both surgical arms reported improvement
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatic-fibrosis_white-paper.pdf
    April 01, 2014 - Of those 45 authors, 28 (62 percent) provided additional data for 29 studies, including 4 who provided … We received information on 10 studies after only one request (34 percent). … Two requests were required for 13 studies (45 percent), and three were required for 6 studies (21 percent … vs. 54 percent, p=0.36). … ) provided data on 7 studies (41 percent), 7, 11, 14, 16, 18, 23, 26 including one dataset. 16
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-202-thermoplasty-comments.pdf
    December 14, 2017 - How was ten percent selected for the clinically important difference? … percent reduction in emergency room visits. … in the year prior to treatment to 50.4 percent in year one and 46.4 percent in year two … the year prior to BT to 8.0 percent and 7.3 percent in years one and two following treatment … percent and 14.5 percent in years one and two post-BT.
  18. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
    January 01, 2006 - About 6 percent of U.S. adults aged 30 years or older have symptomatic osteoarthritis of the knee, and … 3 percent have symptomatic osteoarthritis of the hip. … The total costs for arthritis, including osteoarthritis, may be greater than 2 percent of the gross domestic … • Concomitant low-dose aspirin use increased the rate of endoscopic ulcers by about 6 percent in both … ), which were significantly higher than those for placebo (6 percent) or aspirin alone (7 percent)
  19. Kravitz_ECCS2012 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/kravitz_eccs2012.pdf
    January 01, 2012 - o In a PEW survey,  80 percent  of Internet  users reported that they look for health information … Expectations  for Care • In a study  in which 559 patient visits we audio  recorded: o About 25 percent
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-value-of-information_research.pdf
    June 01, 2011 - of the size of the U.S. population (300 million), 12 percent of the size of the European Union, and … less than 1 percent of the world population (7 billion). … We used a discount rate of 3 percent. … if 310,000 and 92 percent of patients with pancreatic cancer presenting with advanced cancer.47 We … used a discount rate of 3 percent.

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