-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_research-protocol.pdf
January 27, 2012 - AUDs is higher for men than for women, with estimates indicating a lifetime risk of more
than 20 percent … for men.12,14-16 Alcohol dependence has lifetime prevalence rates of
about 17 percent for men and 8 … percent for women.17
AUDs cause substantial morbidity and mortality—that is, threefold to fourfold … Using complete abstinence as an outcome, from 15 to 35 percent of patients have been
reported to achieve … They found that whereas, in aggregate, about 25
percent of individuals maintained sobriety over 1 year
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
May 15, 2017 - Epidemiology
Rheumatoid arthritis (RA), an autoimmune systemic inflammatory arthritis condition,
affects 1 percent … Over 35 percent of patients with RA have
work disability after 10 years.11 The life span of patients … We will include studies with
mixed populations if more than 50 percent of the study populations had … might not be important, 30 percent to 60 percent may represent moderate heterogeneity,
50 percent … to 90 percent may represent substantial heterogeneity, and 75 percent or
greater represents considerable
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/trauma-child-interventions_research-protocol.pdf
March 26, 2012 - However, only 0.5 percent of these trauma-exposed children met
the full criteria for PTSD.1 In a survey … of adolescents 12 to 17 years of age, the 6-month
prevalence for PTSD was 6.3 percent in girls and … 3.7 percent in boys.3 The prevalence of PTSD
in younger children is largely unknown; however, several … One longitudinal study reported that
25 percent of its sample was exposed to or victimized by violence … (excluding sexual trauma), 11
percent was exposed to sexual trauma, and 32 percent was exposed to other
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
February 01, 2013 - age,
sex, race), comorbiditiy (such as diabetes, hypertension),
clinical characteristic (such as percent … When necessary, we arbitrarily assumed a 50 percent
correlation (r=0.5) between baseline and final values … Both
observational studies reported net changes in minimal
lumen diameter (MLD) and percent diameter … At medium term, meta-analysis of six RCTs revealed
a significant 29 percent lower risk of restenosis … Meta-analysis of six RCTs, enrolling almost 1,800
patients, found a significantly 30 percent lower risk
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/protocol-pharm-pregnant-women_0.pdf
December 05, 2018 - Background and Objectives for the Systematic Review
According to Census data, 86 percent of women in … Medicaid claims data from 2000 to 2007 show that 8.1
percent of women were exposed to an antidepressant … ; from 2007 to
2010, the rate increased to 14.8 percent.18 Use of other psychotropic medications during … From 2001 to 2007, use of atypical antipsychotics by pregnant
women more than doubled, from 0.3 percent … to 0.8 percent;19 use of antiepileptic drugs increased
from 1.57 percent of deliveries to 2.19 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
August 01, 2013 - The estimated prevalence
of AF is 0.4 percent to 1 percent in the
general adult population,2,3 occurring … The prevalence increases to about
6 percent in people age 65 or older and
to 10 percent in people age … in patients with a CHADS
2
score of 0 to 18.2 percent in
patients with a CHADS
2
score of 6. … Male sex ranged from 44 percent to 84 percent in
the included studies. … The proportion of male patients
ranged from approximately 40 to 60 percent.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
February 01, 2013 - , specificity 68 percent; ECHO (14 studies): sensitivity
79 percent, specificity 83 percent; SPECT ( … 14 studies): sensitivity 81 percent, specificity 78
percent; CMR (5 studies): sensitivity 72 percent … , specificity 84 percent; and CTA (5 studies):
sensitivity 94 percent, specificity 87 percent. … , specificity 68 percent; ECHO (14 studies): sensitivity
79 percent, specificity 83 percent; SPECT ( … , specificity 84 percent; and CTA (5 studies):
sensitivity 94 percent, specificity 87 percent.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-nonopioid-pharm-chronic-pain.pdf
April 01, 2022 - The machine
learning classifier was previously shown to have 100 percent recall for identifying eligible … All patients in the trial were
pretreated with 4 percent lidocaine cream.6 There was no evidence on … There were also no differences between pregabalin formulations on DPRS 30 and 50 percent
pain reduction … or
more pain improvement (47.5% vs. 32.7%, p=0.004) and 50 percent or more pain improvement
(27.2% … In this
10
RCT, a 5 percent lidocaine patch with 4 percent lidocaine cream premedication was not
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_executive.pdf
January 01, 2010 - The prevalence of asthma in
the United States is approximately
9 percent, and approximately 62 percent … Forty-eight
percent of subcutaneous studies and 61 percent of
sublingual studies had industry support … Local reactions,
reported in 5 percent to 58 percent of patients and
0.6 percent to 54 percent of … We chose to consider a less than 15 percent
difference as a weak magnitude of effect, a 15 percent … to 40 percent difference as a moderate magnitude of
effect, and a greater than 40 percent difference
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
June 01, 2012 - , and the solid red line indicates the true sensitivity of the index test, which is set at 70 percent … OSA has a prevalence of 2 to 4 percent in middle-aged adults. … The 95-percent limits of agreement are very wide in most studies, suggesting great variability in the … An important part of this type of analysis is the range of values defined by the 95-percent limits of … This is the area were 95 percent of the differences are thought to fall.
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-options-summarizing.ppt
June 01, 2012 - , and the solid red line indicates the true sensitivity of the index test, which is set at 70 percent … OSA has a prevalence of 2 to 4 percent in middle-aged adults. … The 95-percent limits of agreement are very wide in most studies, suggesting great variability in the … An important part of this type of analysis is the range of values defined by the 95-percent limits of … This is the area were 95 percent of the differences are thought to fall.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/choice-of-mean_white-paper.pdf
April 01, 2015 - change and 1 (1.4%) used both MD and percent change. … The Knapp-Hartung modification (KH) produced narrower 95 percent CIs
compared to the PE method, but … wider 95 percent CIs than others. … Estimates from PE
method are not available in many cases, and the 95 percent CIs of PE method, when … smaller on average, ranging from 5 percent to more than 40 percent.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
May 01, 2015 - studies of
infants, children, and adults reported rates
of ankyloglossia ranging from 0.1 to 10.7
percent … In infants
with anterior or posterior ankyloglossia,
there is a reported 25- to 80-percent
incidence … of frenotomized infants had improved feeding
within 48 hours, compared with 3 percent in the control … Outcomes that failed to show a difference in
these two RCTs included percent improvement (50% vs.
40% … had major problems with dribbling and 71 percent
had “excess wind” (gas).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_executive.pdf
September 22, 2011 - with
56 percent (56/102) of those using a standard retail
pharmacy. … in the supervised DOT treatment, compared
with 33 percent (8/24) using self-administered treatment … Patients in the intervention groups
had approximately 50-percent higher odds of adhering
to therapy … recommended
course of treatment, compared with 75.0 percent of
patients receiving placebo, although … In the RCT by Ramsey and colleagues,36 50 percent of the
CBT-intervention group were considered to be
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-2005_executive.pdf
January 01, 2005 - In the studies reviewed for this report, from 10
percent to 65 percent of surgical patients still
required … Almost 90 percent of patients who were followed
for 5 or more years in both surgical arms reported
improvement
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatic-fibrosis_white-paper.pdf
April 01, 2014 - Of those 45 authors, 28 (62
percent) provided additional data for 29 studies, including 4 who provided … We received information on 10 studies after only one request (34 percent). … Two requests were
required for 13 studies (45 percent), and three were required for 6 studies (21 percent … vs. 54 percent, p=0.36). … )
provided data on 7 studies (41 percent),
7, 11, 14, 16, 18, 23, 26
including one dataset.
16
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-202-thermoplasty-comments.pdf
December 14, 2017 - How
was ten percent selected for the clinically important
difference? … percent reduction in emergency
room visits. … in the year prior
to treatment to 50.4
percent in year one and 46.4 percent in year two … the year prior
to BT to 8.0 percent and 7.3 percent in years one and two
following treatment … percent and 14.5 percent in years one and two post-BT.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
January 01, 2006 - About 6 percent of U.S. adults aged
30 years or older have symptomatic
osteoarthritis of the knee, and … 3 percent
have symptomatic osteoarthritis of the hip. … The total costs for
arthritis, including osteoarthritis, may be
greater than 2 percent of the gross
domestic … • Concomitant low-dose aspirin use increased the
rate of endoscopic ulcers by about 6 percent in
both … ), which were
significantly higher than those for placebo (6
percent) or aspirin alone (7 percent)
-
effectivehealthcare.ahrq.gov/sites/default/files/kravitz_eccs2012.pdf
January 01, 2012 - o In a PEW survey,
80 percent
of Internet
users reported that they look
for health information … Expectations
for Care
• In a study
in which 559 patient visits we audio
recorded:
o About 25 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-value-of-information_research.pdf
June 01, 2011 - of the size of the U.S. population (300 million), 12 percent of the
size of the European Union, and … less than 1 percent of the world population (7 billion). … We used a discount rate of 3 percent. … if 310,000
and 92 percent of patients with pancreatic cancer presenting with advanced cancer.47 We … used a
discount rate of 3 percent.