-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
July 01, 2012 - limits of agreement (i.e., the region in which 95 percent of the
differences are expected to fall). … When the 95 percent limits of agreement are very broad, the
agreement is suboptimal. … The 95 percent limits of agreement are the
boundaries within which 95 percent of the differences lie … This indicates that the mean bias and 95 percent limits of agreement do not describe adequately
the … For each study, it shows the mean
difference in the two measurements (mean bias) and the 95 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
September 21, 2012 - Many studies also
use a standard required power of 80 percent,
although other values are often considered … using
the crude mortality risk observed in the control
cohort of atypical medication patients (9.58
percent … ), and then assigning the conventional
medication cohort a 10-percent higher risk (10.54
percent), … For example, database studies
may identify small excess risks of about 5 percent
that would fall below … cohort of 23,647 patients who were
eligible for a comparative effectiveness study, but
only 12,840 (54 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-iv-nv-hap-protocol.pdf
August 05, 2024 - the Topic
Pneumonia is the most frequent healthcare-associated infection (HAI), comprising 27.9
percent … of HAIs in the U.S. with 64.5 percent of pneumonia cases not associated with
ventilators contributing … between 2015 and 2020 reported a mortality rate of 22 percent among those who
experienced NV-HAP.8 … of the abstracts have been screened, the human screener
will only examine the remaining 10 percent … To ensure accuracy and consistency, a second reviewer
will review the extracted data from a 10 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
November 01, 2008 - About 30 percent of the primary published
literature on adverse drug events is in the form of case … (95-percent confidence interval [CI], 4.8 percent
to 6.6 percent), compared with 3.7 percent (95-percent … CI, 3.1 percent to 4.3 percent) for studies
meeting fewer than three of the criteria. … to 77.6 percent, -60.4 percent to 377.7 percent, and -43.6 percent
to 496.2 percent, respectively) … , or 18 of
6,568 subjects) than in trials of rofecoxib (0.02 percent, or 2 of 10,174 subjects).
-
effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
November 01, 2008 - About 30 percent of the primary published
literature on adverse drug events is in the form of case … (95-percent confidence interval [CI], 4.8 percent
to 6.6 percent), compared with 3.7 percent (95-percent … CI, 3.1 percent to 4.3 percent) for studies
meeting fewer than three of the criteria. … to 77.6 percent, -60.4 percent to 377.7 percent, and -43.6 percent
to 496.2 percent, respectively) … , or 18 of
6,568 subjects) than in trials of rofecoxib (0.02 percent, or 2 of 10,174 subjects).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_research-protocol.pdf
June 05, 2014 - T2DM accounts for 90–95 percent of cases of diabetes. … ) and diabetes (12
percent). … children and young people in 2009, 74 percent of hospital discharges and 42
percent emergency visits … About 64 percent of these
discharges and 46 percent of the emergency visits were for diabetes ketoacidosis … overweight or obesity (86 percent), hypertension
(58 percent), and high cholesterol (58 percent).3
-
effectivehealthcare.ahrq.gov/sites/default/files/adhd_executive.pdf
October 01, 2011 - at 18
months to 54 percent at 3 to 6 years, limiting
interpretation of the results. … for MPHIR to 75 percent for
amphetamine, 63 percent for OROS MPH, 58 percent
for MAS XR (extended … release), 56 percent for ATX,
and 43 percent for GXR. … appears to be
higher (26 percent) due to ineffectiveness and lower (3
percent) due to adverse events … ) than for children (3
percent).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
September 01, 2011 - Approximately half of these people seek
help for this condition, and only 20 percent
of those receive … vs. 28 percent) than
medications (low strength of evidence). … to 48.9%) and mean remission rates
averaged 22.3 percent (95% CI, 16.2% to 28.4%) … rates averaged 27.2 percent (20.4% to
34.0%) … , 10
percent, 20 percent, etc.?)
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
January 30, 2012 - The estimated prevalence of AF is 0.4 percent to 1 percent in
the general population,2,3 occurring in … The
prevalence increases to about 6 percent in people age 65 or older and to 10 percent in people age … for
patients with AF who are 50 to 59 years old to 23 percent for those who are 80 to 89 years old.9 … in patients with a CHADS2 score of 0 to 18.2 percent in patients with a CHADS2 score
of 6. … reduction in stroke (95
percent confidence interval [95% CI], 49 to 74 percent) when compared to placebo
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_executive.pdf
March 01, 2013 - It is estimated
to affect 11 to 13 percent of reproductive-
age women at any given time. … Prevalence
increases with age, reaching 24 percent
in women aged 36 to 40.1,2 Women
generally present … the study investigators compared with
26 percent of those receiving a placebo. … improvement
in cycle regularity while those who exercised only
had a 42 percent improvement. … of women taking COC compared
with 45 percent for the placebo group.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-233-diverticulitis-evidence-summary.pdf
October 01, 2020 - Among these patients, about 2 percent have CRC, 7 percent have advanced colonic
neoplasia (CRC or advanced … adenoma), and between 1 and 3 percent have specific
premalignant lesions (moderate to high SoE). … moderate SoE that serious
adverse events are uncommon with elective surgery, including that fewer than 1 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-radiation_executive.pdf
November 01, 2009 - Seven studies (3 percent) focused
on a pediatric population; most of the remaining studies
reported mean … OvS=overall survival.
3
Most studies reported patient relevant-clinical
outcomes: 151 studies (62 percent … ) described overall
survival; 112 studies (46 percent), cancer specific
survival; and 210 studies (86 … percent), other surrogate
outcomes of overall survival. … Seventy-five percent of studies (188) reported the
adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_executive.pdf
June 01, 2012 - ), motor vehicle accidents
(17.3 percent), “struck by/against” events
(16.5 percent), assaults (10 … percent), and
other/unknown (21 percent); and, for
military personnel, explosions/blasts.4
TBIs are … By one estimate, two percent of the U.S. … to 47 percent, and among those in standard care from
12 percent to 21 percent.35 This difference disappeared … ) no longer significantly
different from the ICRP rate (60 percent).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/care-adults-down-syndrome-protocol-amendment.pdf
February 05, 2025 - in the general
population.8 Cervical spine disease in adults with Down syndrome occurs with a 2-20 percent … affects up to 73 percent of adults with Down syndrome, overweight/obesity 34-38
percent, and congenital … heart disease 40-50 percent.8 Sleep apnea is highly prevalent in adults
with Down syndrome, with an … estimated range of 40-88 percent.9 Osteopenia/osteoporosis also
affects over 50 percent of this population … Most adults with Down
syndrome receive suboptimal preventive health care.15, 18 Also, 20 percent of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/care-adults-down-syndrome-protocol.pdf
July 09, 2024 - in the general
population.8 Cervical spine disease in adults with Down syndrome occurs with a 2-20 percent … affects up to 73 percent of adults with Down syndrome, overweight/obesity 34-38
percent, and congenital … heart disease 40-50 percent.8 Sleep apnea is highly prevalent in adults
with Down syndrome, with an … estimated range of 40-88 percent.9 Osteopenia/osteoporosis also
affects over 50 percent of this population … Most adults with Down
syndrome receive suboptimal preventive health care.15, 18 Also, 20 percent of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
January 01, 2017 - electrocautery=4.9 percent; and coblation=3.3 percent. … Frequency of readmissions/revisits or reoperation were 1.8
percent and 0.64 percent across all types … Frequency of
readmission related to PTH ranged from 0.2 percent to 6
percent. … technique, and secondary PTH
below 3 percent. … PTH frequency overall was less than 10 percent.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breastfeeding_research-protocol.pdf
January 01, 2020 - weaning.14 The estimates for any breastfeeding for infants born in
2013 in the United States were 81.1 percent … for initiation, 51.8 percent for infants
breastfed at 6 months, and 30.7 percent for infants breastfed … , 66.6 percent, and 34.1 percent,
respectively.17 There are racial and ethnic differences in breastfeeding … From 2000–2013, the percentage of women who initiated
breastfeeding went up from 47.4 percent to 66.3 … percent for blacks, 71.8 percent to 84.3
percent for whites, and 77.6 percent to 83.0 percent for Hispanics
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
April 01, 2012 - Among people with psoriasis,
the prevalence of arthritis varies from
6 percent to 42 percent. … In the general
population, the prevalence of PsA is
estimated to be 0.3 percent to 1 percent. … American College of Rheumatology measure of disease activity: response scores based on 20, 50, or 70 percent … Abbreviations: ACR 20 = American College of Rheumatology 20 percent improvement from baseline to endpoint … Abbreviations: ACR 20 = American College of Rheumatology 20 percent improvement from baseline to endpoint
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-outcomes-chronic-kidney-rapid-research.pdf
November 01, 2024 - Severe
periodontitis affects more than 15 percent of American adults,8 constituting a major cause of … HD and in another,33 a reduction by ~20 percent.
3.2.2.3 Nutrition-Related Markers
Serum albumin … reduction of 12–54 percent in the primary studies. … In the
primary studies, median reductions in CRP was ~33.5 percent. … , while for the other 3 SRs,25,30,34 greater than 85 percent was reported.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
February 01, 2013 - (7 to 62 percent). … Data from observation studies indicated
that long-term augmentation ranged from 2.5 percent to 60 percent … augmentation ranging from 7 to 62 percent. … (7
to 62 percent). … Data from observation studies indicates
that long-term augmentation ranged from 2.5 percent to 60 percent