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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
    July 01, 2012 - limits of agreement (i.e., the region in which 95 percent of the differences are expected to fall). … When the 95 percent limits of agreement are very broad, the agreement is suboptimal. … The 95 percent limits of agreement are the boundaries within which 95 percent of the differences lie … This indicates that the mean bias and 95 percent limits of agreement do not describe adequately the … For each study, it shows the mean difference in the two measurements (mean bias) and the 95 percent
  2. effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
    September 21, 2012 - Many studies also use a standard required power of 80 percent, although other values are often considered … using the crude mortality risk observed in the control cohort of atypical medication patients (9.58 percent … ), and then assigning the conventional medication cohort a 10-percent higher risk (10.54 percent), … For example, database studies may identify small excess risks of about 5 percent that would fall below … cohort of 23,647 patients who were eligible for a comparative effectiveness study, but only 12,840 (54 percent
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-iv-nv-hap-protocol.pdf
    August 05, 2024 - the Topic Pneumonia is the most frequent healthcare-associated infection (HAI), comprising 27.9 percent … of HAIs in the U.S. with 64.5 percent of pneumonia cases not associated with ventilators contributing … between 2015 and 2020 reported a mortality rate of 22 percent among those who experienced NV-HAP.8 … of the abstracts have been screened, the human screener will only examine the remaining 10 percent … To ensure accuracy and consistency, a second reviewer will review the extracted data from a 10 percent
  4. 8 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
    November 01, 2008 - About 30 percent of the primary published literature on adverse drug events is in the form of case … (95-percent confidence interval [CI], 4.8 percent to 6.6 percent), compared with 3.7 percent (95-percent … CI, 3.1 percent to 4.3 percent) for studies meeting fewer than three of the criteria. … to 77.6 percent, -60.4 percent to 377.7 percent, and -43.6 percent to 496.2 percent, respectively) … , or 18 of 6,568 subjects) than in trials of rofecoxib (0.02 percent, or 2 of 10,174 subjects).
  5. 8 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
    November 01, 2008 - About 30 percent of the primary published literature on adverse drug events is in the form of case … (95-percent confidence interval [CI], 4.8 percent to 6.6 percent), compared with 3.7 percent (95-percent … CI, 3.1 percent to 4.3 percent) for studies meeting fewer than three of the criteria. … to 77.6 percent, -60.4 percent to 377.7 percent, and -43.6 percent to 496.2 percent, respectively) … , or 18 of 6,568 subjects) than in trials of rofecoxib (0.02 percent, or 2 of 10,174 subjects).
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_research-protocol.pdf
    June 05, 2014 - T2DM accounts for 90–95 percent of cases of diabetes. … ) and diabetes (12 percent). … children and young people in 2009, 74 percent of hospital discharges and 42 percent emergency visits … About 64 percent of these discharges and 46 percent of the emergency visits were for diabetes ketoacidosis … overweight or obesity (86 percent), hypertension (58 percent), and high cholesterol (58 percent).3
  7. effectivehealthcare.ahrq.gov/sites/default/files/adhd_executive.pdf
    October 01, 2011 - at 18 months to 54 percent at 3 to 6 years, limiting interpretation of the results. … for MPH­IR to 75 percent for amphetamine, 63 percent for OROS MPH, 58 percent for MAS XR (extended … release), 56 percent for ATX, and 43 percent for GXR. … appears to be higher (26 percent) due to ineffectiveness and lower (3 percent) due to adverse events … ) than for children (3 percent).
  8. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
    September 01, 2011 - Approximately half of these people seek help for this condition, and only 20 percent of those receive … vs. 28 percent) than medications (low strength of evidence). … to 48.9%) and mean remission rates averaged 22.3 percent (95% CI, 16.2% to 28.4%) … rates averaged 27.2 percent (20.4% to 34.0%) … , 10 percent, 20 percent, etc.?)
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
    January 30, 2012 - The estimated prevalence of AF is 0.4 percent to 1 percent in the general population,2,3 occurring in … The prevalence increases to about 6 percent in people age 65 or older and to 10 percent in people age … for patients with AF who are 50 to 59 years old to 23 percent for those who are 80 to 89 years old.9 … in patients with a CHADS2 score of 0 to 18.2 percent in patients with a CHADS2 score of 6. … reduction in stroke (95 percent confidence interval [95% CI], 49 to 74 percent) when compared to placebo
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_executive.pdf
    March 01, 2013 - It is estimated to affect 11 to 13 percent of reproductive- age women at any given time. … Prevalence increases with age, reaching 24 percent in women aged 36 to 40.1,2 Women generally present … the study investigators compared with 26 percent of those receiving a placebo. … improvement in cycle regularity while those who exercised only had a 42 percent improvement. … of women taking COC compared with 45 percent for the placebo group.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-233-diverticulitis-evidence-summary.pdf
    October 01, 2020 - Among these patients, about 2 percent have CRC, 7 percent have advanced colonic neoplasia (CRC or advanced … adenoma), and between 1 and 3 percent have specific premalignant lesions (moderate to high SoE). … moderate SoE that serious adverse events are uncommon with elective surgery, including that fewer than 1 percent
  12. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-radiation_executive.pdf
    November 01, 2009 - Seven studies (3 percent) focused on a pediatric population; most of the remaining studies reported mean … OvS=overall survival. 3 Most studies reported patient relevant-clinical outcomes: 151 studies (62 percent … ) described overall survival; 112 studies (46 percent), cancer specific survival; and 210 studies (86 … percent), other surrogate outcomes of overall survival. … Seventy-five percent of studies (188) reported the adverse events.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_executive.pdf
    June 01, 2012 - ), motor vehicle accidents (17.3 percent), “struck by/against” events (16.5 percent), assaults (10 … percent), and other/unknown (21 percent); and, for military personnel, explosions/blasts.4 TBIs are … By one estimate, two percent of the U.S. … to 47 percent, and among those in standard care from 12 percent to 21 percent.35 This difference disappeared … ) no longer significantly different from the ICRP rate (60 percent).
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/care-adults-down-syndrome-protocol-amendment.pdf
    February 05, 2025 - in the general population.8 Cervical spine disease in adults with Down syndrome occurs with a 2-20 percent … affects up to 73 percent of adults with Down syndrome, overweight/obesity 34-38 percent, and congenital … heart disease 40-50 percent.8 Sleep apnea is highly prevalent in adults with Down syndrome, with an … estimated range of 40-88 percent.9 Osteopenia/osteoporosis also affects over 50 percent of this population … Most adults with Down syndrome receive suboptimal preventive health care.15, 18 Also, 20 percent of
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/care-adults-down-syndrome-protocol.pdf
    July 09, 2024 - in the general population.8 Cervical spine disease in adults with Down syndrome occurs with a 2-20 percent … affects up to 73 percent of adults with Down syndrome, overweight/obesity 34-38 percent, and congenital … heart disease 40-50 percent.8 Sleep apnea is highly prevalent in adults with Down syndrome, with an … estimated range of 40-88 percent.9 Osteopenia/osteoporosis also affects over 50 percent of this population … Most adults with Down syndrome receive suboptimal preventive health care.15, 18 Also, 20 percent of
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
    January 01, 2017 - electrocautery=4.9 percent; and coblation=3.3 percent. … Frequency of readmissions/revisits or reoperation were 1.8 percent and 0.64 percent across all types … Frequency of readmission related to PTH ranged from 0.2 percent to 6 percent. … technique, and secondary PTH below 3 percent. … PTH frequency overall was less than 10 percent.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/breastfeeding_research-protocol.pdf
    January 01, 2020 - weaning.14 The estimates for any breastfeeding for infants born in 2013 in the United States were 81.1 percent … for initiation, 51.8 percent for infants breastfed at 6 months, and 30.7 percent for infants breastfed … , 66.6 percent, and 34.1 percent, respectively.17 There are racial and ethnic differences in breastfeeding … From 2000–2013, the percentage of women who initiated breastfeeding went up from 47.4 percent to 66.3 … percent for blacks, 71.8 percent to 84.3 percent for whites, and 77.6 percent to 83.0 percent for Hispanics
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
    April 01, 2012 - Among people with psoriasis, the prevalence of arthritis varies from 6 percent to 42 percent. … In the general population, the prevalence of PsA is estimated to be 0.3 percent to 1 percent. … American College of Rheumatology measure of disease activity: response scores based on 20, 50, or 70 percent … Abbreviations: ACR 20 = American College of Rheumatology 20 percent improvement from baseline to endpoint … Abbreviations: ACR 20 = American College of Rheumatology 20 percent improvement from baseline to endpoint
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-outcomes-chronic-kidney-rapid-research.pdf
    November 01, 2024 - Severe periodontitis affects more than 15 percent of American adults,8 constituting a major cause of … HD and in another,33 a reduction by ~20 percent. 3.2.2.3 Nutrition-Related Markers Serum albumin … reduction of 12–54 percent in the primary studies. … In the primary studies, median reductions in CRP was ~33.5 percent. … , while for the other 3 SRs,25,30,34 greater than 85 percent was reported.
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
    February 01, 2013 - (7 to 62 percent). … Data from observation studies indicated that long-term augmentation ranged from 2.5 percent to 60 percent … augmentation ranging from 7 to 62 percent. … (7 to 62 percent). … Data from observation studies indicates that long-term augmentation ranged from 2.5 percent to 60 percent

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