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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pain-chronic_disposition-comments.pdf
    September 01, 2011 - Estimates of the costs, benefits and risks of medications (both opioid and nonopioid) might be mentioned
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-268-racial-disparities-health-healthcare-executive-summary.pdf
    December 01, 2023 - kidney function and lung function; risk assessment for cardiovascular disease, stroke, lung cancer, opioid … study), allocate organs for transplant (2 studies), assess risk of lung cancer (3 studies), predict opioid … management, assessment of lung function, and risk of stroke, lung cancer, postpartum depression, or opioid
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
    January 01, 2015 - The cost of one care process innovation, the Lazarus Opioid Overdose Prevention and Treatment Program … Community-Based Opioid Overdose Prevention Program (Project Lazarus) Initiated in Wilkes County, … Evzio for Emergency Treatment of Opioid Overdose by Nonclinicians Evzio™ (kaléo, Inc., Richmond, … Overdose by Nonclinicians Drug/device combo $186,400,000 $39,100,000 Lazarus Opioid Overdose … Naloxone Evzio, Auto- Injector for Treatment of Opioid Overdose by Non-Clinicians FDA approved a
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-209-evidence-summary-non-pharma-chronic-pain.pdf
    June 01, 2018 - Recently, guidelines on opioid use for chronic pain by the Centers for Disease Control and Prevention … not be considered current. 2 a recommendation on the preferred use of nonopioid treatment over opioid … trials directly compared interventions with opioids and few trials reported effects of interventions on opioid … Recent guidelines from the CDC4 in the United States and the Canadian Guidelines for Opioid Use in Chronic … The effectiveness and risks of long-term opioid therapy for chronic pain: a systematic review for a
  5. effectivehealthcare.ahrq.gov/sites/default/files/draft-appendix-pbt-study-details-results-evidence-tables.xlsx
    May 11, 2021 - Race, Other % Pain Duration Measure (Mean, Median) Pain Duration, months Psychiatric Comorbidity % Opioid … Previous treatment with weak opioid: 42 vs. 38 Previous treatment with strong opioid: 19 vs. 11 96 71 … : 4% (7/167) vs. 4% (7/172) Other opioid: 20% (33/167) vs. 18% (31/172) 339 339 THC 2.7 mg/CBD 2.5 mg … : 9 vs. 13 Opioid: 2 vs. 3 Strong opioid: 3 vs. 0 66 66 THC 2.7 mg/CBD 2.5 mg per 100 mcl oromucosal … Use (Mean Daily Dose [MDD]) Opioid Equivalents Assessment Time (Weeks) Variance Type for Opioid Use
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-chronic-pain-review-q3-tables-f1-4.xlsx
    June 15, 2021 - Race, Other % Pain Duration Measure (Mean, Median) Pain Duration, Months Psychiatric Comorbidity % Opioid … Previous treatment with weak opioid: 42 vs. 38 Previous treatment with strong opioid: 19 vs. 11 96 71 … : 4% (7/167) vs. 4% (7/172) Other opioid: 20% (33/167) vs. 18% (31/172) 339 339 THC 2.7 mg/CBD 2.5 mg … : 9 vs. 13 Opioid: 2 vs. 3 Strong opioid: 3 vs. 0 66 66 THC 2.7 mg/CBD 2.5 mg per 100 mcl oromucosal … Use (Mean Daily Dose [MDD]) Opioid Equivalents Assessment Time (Weeks) Variance Type for Opioid Use
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix-E-Evidence-Tables-E1-E4.xlsx
    November 04, 2021 - Race, Other % Pain Duration Measure (Mean, Median) Pain Duration, months Psychiatric Comorbidity % Opioid … Previous treatment with weak opioid: 42 vs. 38 Previous treatment with strong opioid: 19 vs. 11 96 71 … : 4% (7/167) vs. 4% (7/172) Other opioid: 20% (33/167) vs. 18% (31/172) 339 339 THC 2.7 mg/CBD 2.5 mg … : 9 vs. 13 Opioid: 2 vs. 3 Strong opioid: 3 vs. 0 66 66 THC 2.7 mg/CBD 2.5 mg per 100 mcl oromucosal … Use (Mean Daily Dose [MDD]) Opioid Equivalents Assessment Time (Weeks) Variance Type for Opioid Use
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix-E-Evidence-Tables-E1-E4_0.xlsx
    November 04, 2021 - Race, Other % Pain Duration Measure (Mean, Median) Pain Duration, months Psychiatric Comorbidity % Opioid … Previous treatment with weak opioid: 42 vs. 38 Previous treatment with strong opioid: 19 vs. 11 96 71 … : 4% (7/167) vs. 4% (7/172) Other opioid: 20% (33/167) vs. 18% (31/172) 339 339 THC 2.7 mg/CBD 2.5 mg … : 9 vs. 13 Opioid: 2 vs. 3 Strong opioid: 3 vs. 0 66 66 THC 2.7 mg/CBD 2.5 mg per 100 mcl oromucosal … Use (Mean Daily Dose [MDD]) Opioid Equivalents Assessment Time (Weeks) Variance Type for Opioid Use
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0122_06-29-2009.pdf
    January 01, 2009 - Effective Health Care Topic Number: 0163 Document Completion Date: 6-7-10 1 Results of Topic Selection Process & Next Steps  Nitrous oxide for the management of labor pain will go forward for refinement as a systematic review. The scope of this topic, including populations, interventions, co…
  10. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-lumbar-spondylolisthesis.pdf
    March 01, 2021 - adverse reaction being similar to the stated reason for the intervention (e.g., adverse reaction to opioid
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-lumbar-spondylolisthesis.pdf
    March 01, 2021 - adverse reaction being similar to the stated reason for the intervention (e.g., adverse reaction to opioid
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f1-f4-tables-surveillance-report-2.xlsx
    January 22, 2022 - Race, Other % Pain Duration Measure (Mean, Median) Pain Duration, months Psychiatric Comorbidity % Opioid … Previous treatment with weak opioid: 42 vs. 38 Previous treatment with strong opioid: 19 vs. 11 96 71 … : 4% (7/167) vs. 4% (7/172) Other opioid: 20% (33/167) vs. 18% (31/172) 339 339 THC 2.7 mg/CBD 2.5 mg … : 9 vs. 13 Opioid: 2 vs. 3 Strong opioid: 3 vs. 0 66 66 THC 2.7 mg/CBD 2.5 mg per 100 mcl oromucosal … Use (Mean Daily Dose [MDD]) Opioid Equivalents Assessment Time (Weeks) Variance Type for Opioid Use
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pbt-lsr-draft-ets-rcts.xlsx
    March 15, 2022 - Race, Other % Pain Duration Measure (Mean, Median) Pain Duration, Months Psychiatric Comorbidity % Opioid … Previous treatment with weak opioid: 42 vs. 38 Previous treatment with strong opioid: 19 vs. 11 96 71 … : 4% (7/167) vs. 4% (7/172) Other opioid: 20% (33/167) vs. 18% (31/172) 339 339 THC 2.7 mg/CBD 2.5 mg … : 9 vs. 13 Opioid: 2 vs. 3 Strong opioid: 3 vs. 0 66 66 THC 2.7 mg/CBD 2.5 mg per 100 mcl oromucosal … Use (Mean Daily Dose [MDD]) Opioid Equivalents Assessment Time (Weeks) Variance Type for Opioid Use
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f1-f4-tables-surveillance-report-2_0.xlsx
    February 16, 2022 - Race, Other % Pain Duration Measure (Mean, Median) Pain Duration, Months Psychiatric Comorbidity % Opioid … Previous treatment with weak opioid: 42 vs. 38 Previous treatment with strong opioid: 19 vs. 11 96 71 … : 4% (7/167) vs. 4% (7/172) Other opioid: 20% (33/167) vs. 18% (31/172) 339 339 THC 2.7 mg/CBD 2.5 mg … : 9 vs. 13 Opioid: 2 vs. 3 Strong opioid: 3 vs. 0 66 66 THC 2.7 mg/CBD 2.5 mg per 100 mcl oromucosal … Use (Mean Daily Dose [MDD]) Opioid Equivalents Assessment Time (Weeks) Variance Type for Opioid Use
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f1-f4-tables-surveillance-report-2_0_0.xlsx
    February 16, 2022 - Race, Other % Pain Duration Measure (Mean, Median) Pain Duration, Months Psychiatric Comorbidity % Opioid … Previous treatment with weak opioid: 42 vs. 38 Previous treatment with strong opioid: 19 vs. 11 96 71 … : 4% (7/167) vs. 4% (7/172) Other opioid: 20% (33/167) vs. 18% (31/172) 339 339 THC 2.7 mg/CBD 2.5 mg … : 9 vs. 13 Opioid: 2 vs. 3 Strong opioid: 3 vs. 0 66 66 THC 2.7 mg/CBD 2.5 mg per 100 mcl oromucosal … Use (Mean Daily Dose [MDD]) Opioid Equivalents Assessment Time (Weeks) Variance Type for Opioid Use
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-app-F1-4.xlsx
    January 01, 2022 - Race, Other % Pain Duration Measure (Mean, Median) Pain Duration, Months Psychiatric Comorbidity % Opioid … Previous treatment with weak opioid: 42 vs. 38 Previous treatment with strong opioid: 19 vs. 11 96 71 … : 4% (7/167) vs. 4% (7/172) Other opioid: 20% (33/167) vs. 18% (31/172) 339 339 THC 2.7 mg/CBD 2.5 mg … : 9 vs. 13 Opioid: 2 vs. 3 Strong opioid: 3 vs. 0 66 66 THC 2.7 mg/CBD 2.5 mg per 100 mcl oromucosal … Use (Mean Daily Dose [MDD]) Opioid Equivalents Assessment Time (Weeks) Variance Type for Opioid Use
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-tables-e1-e4-2022-update_0.xlsx
    January 01, 2022 - Race, Other % Pain Duration Measure (Mean, Median) Pain Duration, Months Psychiatric Comorbidity % Opioid … Previous treatment with weak opioid: 42 vs. 38 Previous treatment with strong opioid: 19 vs. 11 96 71 … : 4% (7/167) vs. 4% (7/172) Other opioid: 20% (33/167) vs. 18% (31/172) 339 339 THC 2.7 mg/CBD 2.5 mg … : 9 vs. 13 Opioid: 2 vs. 3 Strong opioid: 3 vs. 0 66 66 THC 2.7 mg/CBD 2.5 mg per 100 mcl oromucosal … Use (Mean Daily Dose [MDD]) Opioid Equivalents Assessment Time (Weeks) Variance Type for Opioid Use
  18. effectivehealthcare.ahrq.gov/products/alcohol-misuse-drug-therapy/clinician
    February 16, 2016 - renal impairment a Naltrexone Oral: 50 to 100 mg per day Intramuscular: 380 mg per month Opioid … antagonist that competitively binds to opioid receptors and blocks the effects of endogenous opioids
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_clinician.pdf
    February 01, 2016 - Severe renal impairmenta Naltrexone Oral: 50 to 100 mg per day Intramuscular: 380 mg per month Opioid … antagonist that competitively binds to opioid receptors and blocks the effects of endogenous opioids
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/dyspnea-protocol-amended.pdf
    May 19, 2020 - Gastrointestinal (constipation, nausea, vomiting) • Pruritus • Urinary retention, dry mouth • Opioid … Gastrointestinal (constipation, nausea, vomiting) • Pruritus • Urinary retention, dry mouth • Opioid

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