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  1. effectivehealthcare.ahrq.gov/products/integrated-pain-management/protocol
    November 10, 2020 - In 2016, over 2 million Americans reported an opioid use disorder, 6 and an estimated 17,087 deaths … involved prescription opioid overdose. 7 In adults ≥65 years, there were substantial increases in opioid-related … opioid use disorder. … Association of disability with mortality from opioid overdose among US Medicare adults. … Opioid Treatments for Chronic Pain. Comparative Effectiveness Review No. 229.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-testing-machine-learning-tool-chronic-pain.pdf
    November 01, 2020 - The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain. … / 10. opioid*.ti,ab,kw. 11. … Opioid Treatments for Chronic Pain KQ 1-3 (Treatment) 1. … Opioid Treatments for Chronic Pain Afilalo M, Etropolski MS, Kuperwasser B, et al. … J Opioid Manag. 2015;11(6):507-518. PMID: 26728648.
  3. effectivehealthcare.ahrq.gov/products/noninvasive-nonpharm-pain-update/protocol
    March 01, 2019 - At the same time, the NPS points to the "dual crises" of chronic pain and opioid dependence, overdose … The recent publication of evidence-based guidelines on opioid use for chronic pain by the Centers for … Trends in long-term opioid therapy for chronic non-cancer pain. … Opioid prescriptions by U.S. primary care physicians from 1992 to 2001. … Vital signs: overdoses of prescription opioid pain relievers---United States, 1999--2008.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
    December 11, 2018 - The recent publication of evidence-based guidelines on opioid use for chronic pain by the Centers for … Given this need and wide- spread concern regarding opioid use and misuse outlined in recent guidelines … Trends in long-term opioid therapy for chronic non-cancer pain. … Opioid prescriptions by U.S. primary care physicians from 1992 to 2001. … Vital signs: overdoses of prescription opioid pain relievers---United States, 1999--2008.
  5. effectivehealthcare.ahrq.gov/sites/default/files/cer-251-integrated-pain-management-evidence-summary.pdf
    October 01, 2021 - and assessed strength of evidence (SOE) for the primary outcomes of function, pain, and changes in opioid … with a least low strength of evidence for IPMPs for noncancer pain: Key Question 1 (pain, function, opioid … months) None + No evidence No evidence Long term (≥12 months) None + None + None + Opioid … factors were not generally reported in studies; we could not evaluate their impact on function, pain, or opioid
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
    September 20, 2017 - At the same time, the NPS points to the “dual crises” of chronic pain and opioid dependence, overdose … The 2016 CDC Guidelines for Prescribing Opioids for Chronic Pain recommend that non-opioid therapy … Trends in long-term opioid therapy for chronic non-cancer pain. … Opioid prescriptions by U.S. primary care physicians from 1992 to 2001. … Vital signs: overdoses of prescription opioid pain relievers---United States, 1999--2008.
  7. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - Buprenorphine implant (Probuphine) for treatment of opioid dependence No high-impact potential at this … The buprenorphine implant, Probuphine, developed for treating opioid dependence, uses a new delivery … Opioid abuse is one of the most common forms of prescription drug abuse. … Opioid dependency ES-3 management includes medically supervised detoxification and opiate replacement … Available short-acting treatments for opioid dependence (e.g., naltrexone, methadone, buprenorphine
  8. Appendixes A-I (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-annual-update2-appendices.pdf
    January 16, 2023 - Opioid treatments for chronic pain. … , MME 69.4 mg/day 24 weeks Whole plant extracted and long-acting opioid A vs. … b Only included outcome reported was opioid-use. D-11 Appendix D-2. … Does integrative medicine reduce prescribed opioid use for chronic pain? … The impact of Cannabis access laws on opioid prescribing.
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3.pdf
    May 01, 2022 - Opioid treatments for chronic pain. … Opioid Treatments for Chronic Pain. Comparative Effectiveness Review No. 229. … b Only included outcome reported was opioid-use. … Does integrative medicine reduce prescribed opioid use for chronic pain? … The impact of cannabis access laws on opioid prescribing.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3_0.pdf
    May 01, 2022 - Opioid treatments for chronic pain. … Opioid Treatments for Chronic Pain. Comparative Effectiveness Review No. 229. … b Only included outcome reported was opioid-use. … Does integrative medicine reduce prescribed opioid use for chronic pain? … The impact of cannabis access laws on opioid prescribing.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-1.pdf
    June 01, 2022 - Opioid Pharmacologic Therapy No new studies addressed the comparative effectiveness or harms of opioid … What are the effects of prescribing opioid therapy versus not prescribing opioid therapy for acute treatment … the accuracy of instruments for predicting risk of opioid misuse, opioid use disorder, or overdose? … the effectiveness of instruments for predicting risk of opioid misuse, opioid use disorder, or overdose … Opioid Therapy: KQ1 a-e.
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-apps-a-e-surveillance-report-2.pdf
    January 01, 2022 - Opioid Treatments for Chronic Pain. Comparative Effectiveness Review No. 229. … J Opioid Manag. 2009 Nov-Dec;5(6):341-57. PMID: 20073408. 13. … Opioid Treatments for Chronic Pain. Comparative Effectiveness Review No. 229. … b Only included outcome reported was opioid-use. … Does Integrative Medicine Reduce Prescribed Opioid Use for Chronic Pain?
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-apps-a-e-surveillance-report-2-final.pdf
    February 01, 2022 - Opioid Treatments for Chronic Pain. Comparative Effectiveness Review No. 229. … J Opioid Manag. 2009 Nov-Dec;5(6):341-57. PMID: 20073408. 13. … Opioid Treatments for Chronic Pain. Comparative Effectiveness Review No. 229. … b Only included outcome reported was opioid-use. … Does Integrative Medicine Reduce Prescribed Opioid Use for Chronic Pain?
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-apps-a-e-surveillance-report-2-final_0.pdf
    March 01, 2022 - Opioid Treatments for Chronic Pain. Comparative Effectiveness Review No. 229. … J Opioid Manag. 2009 Nov-Dec;5(6):341-57. PMID: 20073408. 13. … Opioid Treatments for Chronic Pain. Comparative Effectiveness Review No. 229. … b Only included outcome reported was opioid-use. … Does Integrative Medicine Reduce Prescribed Opioid Use for Chronic Pain?
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-apps-a-e-surveillance-report-2-final_0_0.pdf
    March 01, 2022 - Opioid Treatments for Chronic Pain. Comparative Effectiveness Review No. 229. … J Opioid Manag. 2009 Nov-Dec;5(6):341-57. PMID: 20073408. 13. … Opioid Treatments for Chronic Pain. Comparative Effectiveness Review No. 229. … b Only included outcome reported was opioid-use. … Does Integrative Medicine Reduce Prescribed Opioid Use for Chronic Pain?
  16. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2022.pdf
    January 01, 2022 - .............................................. 4 Impact Snapshot 1: AHRQ Reports inform CDC’s 2022 Opioid … harms, opioid medications are often prescribed for many pain conditions. … This has resulted in greater incidence of opioid use disorder and opioid-related overdose death. … The CDC guidance continues to recommend non-opioid options as first line of treatment for pain. … Opioid Treatments for Chronic Pain 15.
  17. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-pain-management-grand-rounds-slides.pptx
    March 01, 2022 - Examine the role of opioids in pain management and the opioid crisis. 4. … disorder, serious adverse events) Secondary: Psychological (depression and anxiety), quality of life, opioid … , sedation, nausea); studies not designed to assess serious risks, long-term outcomes, or impact on opioid … systematic reviews as outlined by AHRQ Patient: Adults with episodic migraine Intervention: Systemic opioid … nonopioid abortive drug, or noninvasive nonpharmacologic abortive therapy Comparison: Placebo, another opioid
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_consumer.pdf
    November 01, 2016 - ��Taking opioids while pregnant may cause the unborn baby to have a condition called neonatal opioid
  19. effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_research_executive.pdf
    February 01, 2016 - NSAID No difference 6 RCTs Moderate -- -- -- Opioid vs. … opioid vs. short-acting opioid No clear difference* 6 RCTs Low -- -- -- Benzodiazepine (diazepam) … NSAID No difference 6 RCTs Moderate -- -- -- Opioid vs. … opioid vs. short-acting opioid No clear difference* 6 RCTs Low -- -- -- Benzodiazepine (diazepam) … opioid vs.
  20. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/cer-250-cannabis-surveillance-report-3.pdf
    May 01, 2022 - Opioid treatments for chronic pain. … Opioid Treatments for Chronic Pain. Comparative Effectiveness Review No. 229. … b Only included outcome reported was opioid-use. … Does integrative medicine reduce prescribed opioid use for chronic pain? … The impact of cannabis access laws on opioid prescribing.

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