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1. Prevention, Diagnosis, and Management of Opioids, Opioid Misuse and Opioid Use Disorder in Older Adults: Protocol (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioids-oa-protocol.pdf
   June 29, 2019 - Prevention, Diagnosis, and Management of Opioids, Opioid Misuse and Opioid Use Disorder in Older Adults … c. identify opioid misuse or opioid use disorder in older adults? … disorders, opioid misuse, and opioid- related adverse events. … and opioid analgesics. … opioid use.

2. Topic-Brief2-Opioid-Withdrawal (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief2-opioid-withdrawal.pdf
   April 01, 2021 - as opioid use disorders, and it has other properties including less opioid-induced hyperalgesia and … , opioid dose, likelihood of opioid discontinuation, and adverse events (including overdose and mortality … Effective Treatments for Opioid Addiction. … No shortcuts to safer opioid prescribing. … The search strategy included terms for pain and opioid tapering.

3. Topic-Brief2-Opioid-Withdrawal (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief2-opioid-withdrawal.pdf
   April 01, 2021 - as opioid use disorders, and it has other properties including less opioid-induced hyperalgesia and … , opioid dose, likelihood of opioid discontinuation, and adverse events (including overdose and mortality … Effective Treatments for Opioid Addiction. … No shortcuts to safer opioid prescribing. … The search strategy included terms for pain and opioid tapering.

4. Prevention, Diagnosis, and Management of Opioids, Opioid Misuse, and Opioid Use Disorder in Older Adults | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/opioids-older-adults/report

5. Disposition of Comments: Technical Brief 37 Prevention, Diagnosis, and Management of Opioids, Opioid Misuse, and Opioid Use Disorder in Older Adults (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-37-opiod-use-adults-comments.pdf
   November 03, 2020 - and opioid use disorder and reducing opioid-related harms. … for opioid misuse or opioid use disorder, and management of misuse or opioid use disorder. … use, opioid-related disorders, opioid misuse, and opioid-related adverse events yielding 5402 citations … opioid use disorder, and reducing opioid related harms. … treatments, prevent opioid misuse or OUD, and reduce the risk of opioid-related harms when opioid

6. Prevention, Diagnosis, and Management of Opioids, Opioid Misuse and Opioid Use Disorder in Older Adults | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/opioids-older-adults/protocol

7. Opioid Abuse and Addiction | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/health-topics/opioid-abuse-and-addiction

8. Making Healthcare Safer IV: Opioid Stewardship | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/mhs4-opioid-stewardship/protocol

9. Treatments and Technologies Supporting Appropriate Opioid Tapers | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/appropriate-opioid-tapers/research

10. Opioid Treatments for Chronic Pain Research Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-treatments-chronic-pain-protocol.pdf
    December 19, 2018 - The majority of heroin users report their first opioid of abuse was a prescribed opioid, and concerns … The review found that long-term opioid therapy was associated with increased risk of overdose, opioid … / 10. opioid*.ti,ab,kw. 11. … / 10. opioid*.ti,ab,kw. 11. … / 10. opioid*.ti,ab,kw. 11.

11. | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/opioid-abuse-addiction

12. EHC Protocol: Making Healthcare Safer IV: Opioid Stewardship (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-opioid-stewardship-protocol.pdf
    July 01, 2023 - EHC Protocol: Making Healthcare Safer IV: Opioid Stewardship 1 Evidence-based Practice Center … interventions on key opioid prescribing and clinical outcomes (e.g., opioid dosage, opioid prescriptions … The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain. … Opioid Use. … National Quality Partners Playbook: Opioid Stewardshp. 2018.

13. Making Healthcare Safer IV: Opioid Stewardship | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/mhs4-opioid-stewardship/rapid-research

14. Medication-Assisted Treatment Models of Care for Opioid Use Disorder | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/opioid-use-disorder/research-protocol

15. The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/chronic-pain-opioid-treatment/research

16. CER 229 Evidence Summary: Opioid Treatments for Chronic Pain (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
    April 01, 2020 - and harms of opioid therapy for chronic noncancer pain, alternative opioid dosing strategies, and … Opioid plus nonopioid vs. opioid • An opioid plus nonopioid was associated with greater improvement in … Opioid plus nonopioid vs. opioid • No differences between an opioid plus nonopioid vs. an opioid alone … ’s 2016 Opioid Guideline. … Opioid medication discontinuation and risk of adverse opioid-related health care events.

17. App-D-Opioid-Chronic-Pain-Surveill-Report-1 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveill-report-1.xlsx
    September 30, 2015 - 5.6% vs. 3.9% vs. 8.8% vs. 9.1%, p=0.912 Opioid abuse: 20.6% vs. 14.5% vs. 6.6% vs. 9.1%, p<0.001 Opioid … users had ≥90 days Patients ≥65 years on long-term opioid therapy ≥ with new long-term opioid therapy … use (n=634) B) Intermittent opioid use (n=746) C) No opioid use (n=2,792) Age, years 18 to 39: 6.3% … use collected in 5 interview rounds over 2 years A) Persistent opioid use: opioid use reported in 2 … consecutive rounds before the last round of followup B) Intermittent opioid use: opioid use reported

18. App-D-Opioid-Chronic-Pain-Surveillance-Report-3 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-3.xlsx
    September 30, 2015 - n=290 A: Involuntary opioid reduction (n=88) B: Voluntary opioid reduction (n=96) C: No opioid reduction … ≥65 years on long-term opioid therapy ≥ with new long-term opioid therapy use episode, continuously … use (n=634) B: Intermittent opioid use (n=746) C: No opioid use (n=2,792) Age, years 18 to 39: 6.3% … use collected in 5 interview rounds over 2 years A) Persistent opioid use: opioid use reported in 2 … consecutive rounds before the last round of followup B) Intermittent opioid use: opioid use reported

19. App-D-Opioid-Chronic-Pain-Surveillance-Report-2 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
    September 30, 2015 - 5.6% vs. 3.9% vs. 8.8% vs. 9.1%, p=0.912 Opioid abuse: 20.6% vs. 14.5% vs. 6.6% vs. 9.1%, p<0.001 Opioid … users had ≥90 days Inclusion: Patients ≥65 years on long-term opioid therapy ≥ with new long-term opioid … use (n=634) B: Intermittent opioid use (n=746) C: No opioid use (n=2,792) Age, years 18 to 39: 6.3% … use collected in 5 interview rounds over 2 years A) Persistent opioid use: opioid use reported in 2 … consecutive rounds before the last round of followup B) Intermittent opioid use: opioid use reported

20. App-E-Opioid-Chronic-Pain-Surveillance-Report-2 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-2.xlsx
    January 01, 2021 - Table E-1. RCT QA Table E-1. RCT quality assessment Author, Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-To-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…