-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/measuring-blood-pressure-future_research.pdf
August 01, 2012 - i.e., after longer followup periods (1O1)
Unclear if the effect of SMBP is sustained beyond 1-2
years … i.e., after longer followup periods (1O1)
Unclear if the effect of SMBP is sustained beyond 1-2
years … Therefore, it is currently uncertain if patient adherence to
SMBP is sustained beyond 1 to 2 years, … A reasonable time frame for
such studies would be 2 to 3 years to demonstrate prolonged effects. … The event rate in
the entire control group over a mean of 5 years was 18 percent.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0261_07-16-2010.pdf
January 01, 2010 - Staff-Generated PICO:
Population(s): Clinicians treating children age 0-18 years diagnosed with asthma
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0623-140828.pdf
April 25, 2014 - defined as the inability to conceive after 12 months
(or in six months if a woman is older than 35 years
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0004_03-11-2008.pdf
January 01, 2008 - Despite the fact that these reviews have existed for several years and have shown a potential
benefit
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/suicide-prevention_research-protocol.pdf
December 23, 2015 - suicide prevention, annual all-ages suicide rates in the United States have been stable
for the past 60 years … interventions
with the potential to reduce morbidity (attempts) and mortality (deaths), by at least 20% in 5
years … , and 40% or greater in 10 years. … Time lag for available data
There is a significant lag (~2-3 years) from when suicides happen and when … The figure illustrates how data, in populations 6
to 25 years old, from suicide prevention interventions
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_executive.pdf
December 01, 2015 - population over a lifetime.2,3
Appendicitis has its highest incidence
between the ages of 10 and 30 years … Separate analyses were performed
for children (age <18 years), adults (age ≥18 years),
women of reproductive … We initially planned to separately examine the
subgroup of very young children (<2 years and 2–5 years … 0.63 (0.47 to 0.77)
Children 22 (3,952/3,845) 0.51 (0.41 to 0.61) 0.72 (0.66 to 0.77)
Children <5 years … (0.56 to 0.76)
Tenderness Children 2 (206/474) 0.63 (0.26 to 1.00) 0.57 (0.46 to 0.68)
Children <5 years
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sodium-potassium_research-protocol.pdf
April 18, 2017 - stage and gender group.2
The 2005 IOM report set the AI for sodium for the population aged 19-50 years … The
IOM set the UL for sodium at 2,300 mg per day for people aged 14 years and over, with
lower values … for those 1-13 years of age. … • Timing
o Only interventions of two years or longer will be included for kidney
disease outcomes … , studies reporting exclusively on kidney
disease need to follow participants for at least two years
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ear-infection_executive.pdf
May 01, 2013 - with watchful
waiting or myringotomy (data combined), there was a
13 percent reduction through 2 years … The review included
five studies with children82-86 and one study with adults,
16–75 years of age.87 … With one
exception, studies examining children during preschool
and elementary school years failed … the investigators used a teacher
rating of children’s language; this difference disappeared
at 8 years … Tympanostomy
tubes and developmental outcomes at 9 to 11 years of age.
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1406.pdf
June 01, 2014 - system
is intended to identify interventions that purport to address an unmet need and are up to 3 years … out
on the horizon and then to follow them up to 2 years after initial entry into the health care … Topics eligible for
inclusion are those interventions expected to be within 0–3 years of potential … patients (n=56) with unicompartmental osteoarthritis of the
knee and genu varum who were aged 55 years … Also in the 2 years after treatment, significant clinical improvements were observed in
the PRP group
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/trauma-interventions-maltreatment-child_research-protocol.pdf
January 12, 2012 - outcomes, timing, and setting (PICOTS)
Domain Description
Population Children ages 0 to 14 years … Therapy, Attachment and Biobehavioral Catch-up [ABC], Child-Parent Psychotherapy, the
Incredible Years … The decision was made to exclude
adolescents older than 14 years of age due to
concerns about the … Key Questions Referred to age
groups 0 to 2 years
(infant/toddler), 3
to 5 years
(preschool) … , 6 to
12 years (middle
childhood), and 13
to 17 years
(adolescence)
Does not specify
age
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury_executive.pdf
April 01, 2011 - Community integration, social support and life
satisfaction in relation to symptoms 3 years after mild … Psychiatric
challenges in the first 6 years after traumatic brain injury:
cross-sequential analyses of … Psychosocial
adjustment and employment outcome 2, 5 and 10 years after
TBI. … The effects of
severe head injury on patient and relative within seven years
of injury. … Family functioning and
emotional state two and five years after traumatic brain injury.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/insulin-blood-sugar-2010_executive.pdf
January 01, 2010 - The mean age of participants
in the RCTs was 16.5 years in the MDI group and
11.4 years in the CSII … The mean age of the study populations ranged
from 26 to 31 years. … The mean age of participants
in the RCTs was 24 years (range, 8.5 to 41.2 years) in the
rt-CGM group … and 25 years (range, 9.1 to 44.6 years) in
the SMBG group. … Since few studies included children
12 years of age or younger, adults 65 years of age or older,
or
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ankyloglossia_research-protocol.pdf
June 30, 2014 - significance of this anomaly and the best method of management have been controversial for
more than 50 years … Recognition of potential benefits of breastfeeding in recent years has resulted in a renewed
interest … other chiropractic therapies), lactation intervention, and speech therapy (for children
ages 2-18 years … KQ3)
What are the benefits and harms of various treatments for ankyloglossia in children up to 18
years … or with ankylo-
glossia and
tight labial
frenula ages 0
to 18 years
Intermediate
outcomes
-
effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
January 01, 2012 - system is intended
to identify interventions that purport to address an unmet need and are up to 7 years … out on the
horizon and then to follow them for up to 2 years after initial entry into the health care … Topics eligible for
inclusion are those interventions expected to be within 0–4 years of potential … SEQUEL trial results for Qnexa published in
AJCN show 10% sustained weight loss over 2
years. … Durable
weight loss and metabolic improvement at two
years with the EndoBarrier (DJBL).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
January 01, 2007 - 2005, the prevalence of Americans with
diagnosed type 2 diabetes was 2.4 percent
for adults aged 20-39 years … , 10 percent for
adults aged 40-59 years, and 21 percent for
adults aged 60 years or over. … populations,
such as those based on demographic factors (e.g.,
race/ethnicity, age greater than 65 years … between metformin and
other oral diabetes medications or placebo (8.4 vs. 9
cases per 100,000 patient-years … primary end point of
hospitalization or death from cardiovascular disease
after a mean followup of 3.7 years
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
December 23, 2014 - the elderly population.5,6 In 2011 93 percent of
deaths from C. difficile occurred in persons ≥65 years … use enzyme immunoassay because it is fast, inexpensive, and
technically easy to perform.17 Just 3 years … -
1 difficile.mp.
2 limit 1 to (english language and humans)
3 limit 2 to ("all adult (19 plus years … )" or "young adult (19 to 24 years)" or "adult (19 to 44
years)" or "young adult and adult (19-24 and … 19-44)" or "middle age (45 to 64 years)" or
"middle aged (45 plus years)" or "all aged (65 and over
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
August 01, 2013 - and exclusion criteria
Category Inclusion Criteria Exclusion Criteria
Population KQ1: Adult (≥18 years … KQ2 & KQ3: Adults (≥18 years) with a diagnosis of subjective idiopathic
(nonpulsatile) tinnitus who … seeking a treatment intervention
No restriction on the length of time of symptoms
•Subjects <18 years … study populations were relatively
homogeneous and were limited to predominately middle-
aged (≥50 years … the experience of
tinnitus based on recent epidemiological research on adults
over the age of 45 years
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-adolescents_research-protocol.pdf
March 29, 2011 - There is also evidence to suggest that specifically the young adult years might be a time of higher … papers that include participants with ASD in our
target age range as well as those over 30 or under 12 years … deviance in language acquisition (e.g.,
single non-echoed words are used communicatively by age 2 years … , and spontaneous
communicative phrases are used by age 3 years) (Criterion D), although more subtle … In
addition, during the first 3 years of life, there are no clinically significant delays in cognitive
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
June 01, 2013 - system is intended
to identify interventions that purport to address an unmet need and are up to 4 years … out on the
horizon and then to follow them up to 2 years after initial entry into the health care … Topics eligible for
inclusion are those interventions expected to be within 0–4 years of potential … and Drug Administration (FDA) granted marketing
approval for ivacaftor for treating patients aged 6 years … In January 2012, FDA approved ivacaftor for treating patients aged 6 years or
older who have a G551D
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-applicability_methods.pdf
January 01, 2011 - used to inform Medicare coverage
enrolled patients who were significantly younger (60.1 vs. 74.7
years … centers
where the perioperative risk is less than 3 percent and who were followed an average of 4
years … from 1967-1975
Watchful
waiting with
oral placebo
Overall
mortality;
Median follow-
up 23 years … The smaller trial3
was conducted over 20 years ago and may not be applicable. … Additional follow-up from one
study suggests that outcomes at 10 years are representative of longer-term