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  1. effectivehealthcare.ahrq.gov/sites/default/files/06_devdelays_autism_potential_high_impact_june_2012.pdf
    January 01, 2012 - system is intended to identify interventions that purport to address an unmet need and are up to 7 years … out on the horizon and then to follow them for up to 2 years after initial entry into the health care … Topics eligible for inclusion are those interventions expected to be within 0–4 years of potential
  2. effectivehealthcare.ahrq.gov/sites/default/files/upenn-final-report-2005-certs-ce-supplement.pdf
    January 01, 2005 - or about 12-19% of all deaths in the US,5,6 and is the leading cause of death in adults less than 65 years … These states constitute approximately 30 million person-years of Centers for Medicare & Medicaid Services … Results: Queries of the CMS claims data identified 477 SCD/VA events occurring within 127,106 person-years
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/administrative-data-validity_research.pdf
    January 01, 2007 - or about 12-19% of all deaths in the US,5,6 and is the leading cause of death in adults less than 65 years … These states constitute approximately 30 million person-years of Centers for Medicare & Medicaid Services … Results: Queries of the CMS claims data identified 477 SCD/VA events occurring within 127,106 person-years
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_executive.pdf
    January 01, 2014 - Timing SOEa and Effect Estimate (95% CI) Composite of all-cause mortality or nonfatal MI within 2 years … and Timing SOEa and Effect Estimate (95% CI) Cardiovascular mortality at 6 months, 1 year, and 2 years … RCTs and 1 observational) showed no statistically significant difference in event rates at 1 or 2 years … Major bleeding at 1 year and 2 years SOE = Insufficient (3 RCTs; 5,572 patients) Insufficient evidence … to unknown precision: triple therapy 3.3%; warfarin/aspirin 4.5% (p = 0.49) Nonfatal MI at 1 to 5 years
  5. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/tympanostomy-tubes_research-protocol.pdf
    November 16, 2015 - children into a treatment pathways database and a Medicaid database, 2.5 percent of all U.S. children 2 years … will be: Populations All KQs: Ages: infant (28 days to 12 months), toddler (13 months to 2 years … ), early childhood (2 to 5 years), middle childhood (6 to 11 years), early adolescence (12 to 18 years … T-tubes, typically remain in place for several years) •   KQ 4: Water precautions o   Avoidance … The medical appropriateness of tympanostomy tubes proposed for children younger than 16 years in the
  6. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/deficit-hyperactivity-protocol.pdf
    November 01, 2021 - diagnostic procedures is approximately 5.3 percent, a rate that has remained constant over the more than 20 years … primary care practice setting or by specialists to diagnose ADHD among individuals younger than 7 years … of age without the diagnosis of ADHD KQ 2 (treatment): Individuals birth through 17 years of age … is not greater than 21 years of age KQ3: For long-term studies, the age of the individuals will … imaging, or assessment of executive function for the diagnosis of ADHD in individuals through 17 years
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/structured-handoff-protocol.pdf
    December 31, 2024 - were responsible at least in part for 30% of all malpractice claims and more than 1700 deaths over 5 years … was published in 2018 on the IPASS tool20 but no review has been published in the intervening 6 years … the specificity of the search), and restricting the search to studies published in the last 10 years … not been discussed in detail in prior editions of MHS, we will expand our search to the past 10 years
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-infection-prevention-mdro-protocol.pdf
    July 01, 2023 - Criteria Study Parameter Inclusion criteria Exclusion criteria Population Adult patients (18+ years … ) Pediatric patients (under 18 years) Intervention • Surveillance testing • Barrier precautions … will be organized according to the review questions, and will include author, publication year, data years … Classification of healthcare-associated infection: a systematic review 10 years after the first proposal
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-appendix-c-prepub-final.xlsx
    January 01, 2025 - Percent Participants Age > 65 Years Number Participants Age < 50 Years Percent Participants Age < 50 … Years Number of Females, Overall Number of Females Cases Number of Females, Controls Percent Females … Participants were between 40 and 75 years old. … The mean age of the participants (analysis 1) was 58 (IQR: 50–64) years. … 8 (control group) 60 to 92 years old: 50.8 (cancer group); 5.6 (control group) 19 to 59 years old: 88
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-final-app-c.xlsx
    January 01, 2025 - Percent Participants Age > 65 Years Number Participants Age < 50 Years Percent Participants Age < 50 … Years Number of Females, Overall Number of Females Cases Number of Females, Controls Percent Females … Participants were between 40 and 75 years old. … The mean age of the participants (analysis 1) was 58 (IQR: 50–64) years. … 8 (control group) 60 to 92 years old: 50.8 (cancer group); 5.6 (control group) 19 to 59 years old: 88
  11. effectivehealthcare.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_june_2012.pdf
    January 01, 2012 - system is intended to identify interventions that purport to address an unmet need and are up to 7 years … out on the horizon and then to follow them for up to 2 years after initial entry into the health care … Topics eligible for inclusion are those interventions expected to be within 0–4 years of potential … Although AD is potentially fatal, patients can live as long as 20 years after diagnosis and often have … The anticipated doubling of the number of people aged 65 years and older by 2040 portends an increase
  12. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
    April 01, 2012 - system is intended to identify interventions that purport to address an unmet need and are up to 7 years … out on the horizon and then to follow them for up to 2 years after initial entry into the health care … Topics eligible for inclusion are those interventions expected to be within 0 to 4 years of potential … Food and Drug Administration (FDA) in April 2010 to treat adults (aged 18 years and older) with severe … Safety of bronchial thermoplasty out to 5 years in patients with severe refractory asthma: research
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_disposition-comments.pdf
    May 27, 2010 - Methods 5, 42: [why not consider ASCO abstracts] We reviewed the ASCO abstracts for the past five years … These potential differences have been the subject of extensive research in recent years. … Tongue and tonsil carcinoma: increasing trends in the U.S. population ages 2044 years. … These potential differences have been the subject of extensive research in recent years. … Tongue and tonsil carcinoma: increasing trends in the U.S. population ages 20–44 years.
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix-E-Table-E5_0.xlsx
    May 29, 2025 - PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure (Mean, Median) Age, years … Groups unclear A: Self-reported frequent cannabis use (≥20 days/mo) B: No cannabis use NR Total: 208 (4 years
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f5-table-surveillance-report-2_0_0.xlsx
    May 29, 2025 - PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure (Mean, Median) Age, Years … Groups unclear A: Self-reported frequent cannabis use (≥20 days/mo) B: No cannabis use NR Total: 208 (4 years
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0119_06-17-2009.pdf
    January 01, 2009 - Population: All patients with PKU ages 0 years and up, including pregnant women Intervention: Pharmacologic
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0136_07-21-2009.pdf
    January 01, 2009 - Population: Adult females aged 25-65 years with chronic pelvic pain due to adenomyosis, endometriosis
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0647-13114.pdf
    June 21, 2013 - Staff-Generated PICO Population(s): Adults, defined as 18 years of age or older, diagnosed with MDD;
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-foot-ulcer-amputation-prevalence_research.pdf
    February 01, 2011 - The prevalence of diabetes among those over 65 years of age was last estimated by the Centers for Disease … It is about 19.9 percent among those ages 65 to 74 and 17.1 percent among those more than 75 years … More specifically, for beneficiaries age 65 years and over, the prevalence was 26.5 percent in 2006
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypertension-drugs-utilization_research.pdf
    January 25, 2011 - During 1976-1980, only 51 percent of hypertensive patients ages 18-74 years were aware of their hypertension … beneficiaries 2 Hypertension control rates have been shown to be the lowest among individuals age 60 years … above,7 despite the availability of public/government-provided health insurance for those age 65 years … Calculation of Payments for Antihypertensive Drugs: For each of the study years of interest, we used

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