-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
September 01, 2011 - Amgen
requests that the lower limit of the age range be added for abatacept
(6 years), adalimumab ( … 4 years), etanercept (2 years), methotrexate
(2 years), and sulfasalazine (6 years). … Why not for earlier years? … Amgen also requests that the follow-
up durations of 4years and 8 years be added to the second-to-last … etanercept resulted in
sustained improvement in clinically important signs and symptoms for
up to 8 years
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_appendixes.pdf
October 06, 2006 - 61.8 27 91 5 19
BARI PCI Registry 1189 7 years 61.0 26 15
BARI CABG RCT 914 7 years 61.4 26 89 7 … 20
BARI CABG Registry 625 7 years 62.5 26 19
EAST PCI RCT 198 8 years 61.8 25 93 7 25
EAST PCI … Registry 168 3 years 60.3 24.4 92.8 19.2
EAST CABG RCT 194 8 years 61.4 27 94 6 21
EAST CABG Registry … 270 3 years 62.6 18.9 96.3 21.6
AWESOME PCI RCT 222 5 years 67 29
AWESOME PCI Registry—Physician-Directed … 651 5 years 66 31
AWESOME PCI Registry—Patient-Choice 207 5 years 66 32
AWESOME CABG RCT 232
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
November 01, 2013 - ) than
in younger patients (<65 years) to detect left ventricular
ejection fraction (LVEF) <45 (250 … of age and 450 pg/mL for patients ≥75
years of age. … For
detecting LVEF <45 in one study,101 AUCs were 0.88 in
patients ≥65 years (cutpoint 1,446 pg/mL; … years. … • Followup of 2 years or more.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-202-thermoplasty-comments.pdf
December 14, 2017 - Archived: This report is greater than 3 years old. … Alair is indicated for the treatment of severe
persistent asthma in patients 18 years and older whose … Post-Approval Study (PAS2) for Bronchial
Thermoplasty (BT): Results to 2 Years. … We have
reported the findings that FEV1 was
stable over 5 years in the extension
studies. … One of the
extension studies also reported data for
the control arm through 3 years.”
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-protocol-amendment.pdf
March 22, 2023 - In children under 18 years of age diagnosed with disruptive behaviors, which
psychosocial interventions … In children under 18 years of age diagnosed with disruptive behaviors, which
pharmacologic interventions … In children under 18 years of age diagnosed with disruptive behaviors, are combined
psychosocial and … What are the harms associated with treating children under 18 years of age for
disruptive behaviors … Children under 18 years of age who are being
treated for disruptive behavior or a disruptive behavior
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-222-evidence-summary-health-equity.pdf
January 01, 2020 - Breast cancer screening Women age 40 years and oldera
Cervical cancer screening Women age 21 to 65 … years
Lung cancer screening Adults age 55 to 80 years with a
smoking history
Tobacco smoking cessation … prevent cardiovascular
disease and colorectal cancer: preventive
medication
Adults age 50 to 59 years … with obesity and cardiovascular
disease risk factors
High blood pressure screening Adults age 18 years … and older
Diabetes
Abnormal blood glucose and type 2 diabetes
screening
Adults age 40 to 70 years
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-disposition-120104.pdf
April 01, 2011 - complete if it mentioned that
PPIs are approved for short term treatment of GERD in children 1-17
years … This report is
targeted at adults only, children 1 to 17 years
old are excluded in this review. … (Population studied, per the publication, is > 65
years of age).” ES-7. … Geriatric patients (>65 years) were included in Takeda’s clinical
study program of dexlansoprazole, … The
safety of lansoprazole capsules was also assessed in 87 adolescents
12-17 years of age.
-
effectivehealthcare.ahrq.gov/sites/default/files/devdelays_adhd_autism_hi_impact.pdf
January 01, 2012 - system is intended to identify
interventions that purport to address an unmet need and are up to 7 years … out on the horizon and then to
follow them for up to 2 years after initial entry into the health care … Topics eligible for inclusion
are those interventions expected to be within 0 to 4 years of potential … be detected in individuals at 18 months of age or younger, but diagnosis is
usually made by age 2 years … Sixty-two children with autism aged 2 to 7 years
were recruited from 6 centers and randomly assigned
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/trauma-child-interventions_research-protocol.pdf
March 26, 2012 - In one longitudinal study of more than 1,400
children 9 to 16 years of age, 68 percent of children reported … these trauma-exposed children met
the full criteria for PTSD.1 In a survey of adolescents 12 to 17 years … group
intervention for children exposed to trauma who are typically between the ages of 10 and 15
years … Often providers are trained in only one modality of
therapy or were trained many years before and have … Trauma reminders and PTSD symptoms in
children three years after a terrorist attack in Beslan.
-
effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1512.pdf
December 01, 2015 - is intended to identify interventions that purport to address an important unmet need, are up to 3
years … out on the horizon, and if they have potential for high impact, to follow them up to 2 years
after … Topics eligible for
inclusion are those interventions expected to be within 0–3 years of potential … In the United States, the incidence today
is nearly 3 times that of 30 years ago, rising from 3.6 cases … FDA for treating travelers’ diarrhea
caused by E. coli in adults and children who are at least 12 years
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/registry-of-patient-registries_research-2014.pdf
January 01, 2014 - Interest in and use of patient registries have increased in recent years. … expired during
hospital stay4
Population
HbA1c in poor control The percentage of patients 18-75 years … Title Definition
1 HbA1c Management: Poor
Control5
The percentage of patients 18-75 years of age … Members 18 - 75
years of ages
with diabetes. … All discharges,
age 18 years
and older, with a
principal
diagnosis code
of CHF.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-jaw-rapid-response.pdf
May 01, 2025 - limited to English
language studies on human participants and covered publications from the last 15 years … , more than three years), and antiresorptive type
(bisphosphonates, RANKL inhibitors).56 The majority … of
therapy, and >2 years of therapy. … , (3) antiresorptive therapy for
more than 3 years. … Another challenge is that MRONJ may take several years to develop.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
May 15, 2017 - 100,000 annually.2 Onset of RA can begin at any age but increases with age; onset is
highest at 60 years … Over 35 percent of patients with RA have
work disability after 10 years.11 The life span of patients … with RA is 3 to 12 years less
than that of the general population.12 Patients with high disease activity … months of symptoms of disease;13 other organizations have advocated for a later
cut off of up to 2 years … Reductions in
radiographic progression in early RA over 25-years: Changing contribution from
RF in
-
effectivehealthcare.ahrq.gov/sites/default/files/s3.pdf
October 01, 2007 - White observed
“Epidemiology and Health Services” in The Development of Modern Epidemiology,4 was
light years … Harry had a
similar influence on countless students and colleagues over
the ensuing 25 years.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-update_clinician.pdf
September 01, 2014 - Studies
involved children up to age 12 with ASD or ages 0–2 years at
risk for diagnosis of ASD. … � Which specific treatment approaches to use in children
under 2 years of age who are at high risk
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-outcomes-diabetes-rapid-research.pdf
November 01, 2024 - Background
In the past several years, there has been increasing appreciation for the interconnectedness … up to the age of 35 suffer from
periodontal disease, a figure that rises to 80% at the age of 45–54 years … One SR was specifically of patients with
diabetes above the age of 55 years.30 In this SR as well, HbA1c … . (2017): SR of 22 studies (very low quality) including patients with
T2DM and above the age of 55 years … Details of URs mapping to KQ2
Study;
Intervention;
Quality of UR
# SRs; Years;
# of primary
-
effectivehealthcare.ahrq.gov/sites/default/files/hibbard-presentation.pdf
May 29, 2025 - of the research on how this relate to outcomes.
10
This is a study that was published
a few years … magnitudeof the relationship.
11
We’re looking at that 2010 PAM scorepredicting outcomes at two years … normal range in the PHQ-‐9, they were
about two times more likely to be in
the normal rangetwo years
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-child-adolesc-mental-health-grand-rounds.pptx
May 22, 2025 - for other brief assessment tools
36
Key Question 2: PICO
Population: Children and adolescents (<21 years … The rate of suicide-related ED visits for youths aged 5–24 years has also increased. … crisis in which suicide rates have increased dramatically among young people, and over the last few years … Secondary analysis found fewer deaths in YST over 11–14 years. … based
USPSTF-2022
Limited evidence for psych tx
No studies on pharmacological tx
Excluded < 18 years
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-apps-G1-2.xlsx
January 01, 2022 - No No Yes Moderate
Campbell, 2018 Yes Unclear Yes No Yes Unclear/Yes*
20% overall attrition over 4 years
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-3-app-G.xlsx
January 01, 2022 - /No No Yes Moderate
Campbell, 2018 Yes Unclear Yes No Yes Unclear/Yes
20% overall attrition over 4 years