-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_disposition-comments.pdf
January 01, 2015 - This is particularly the case with the weight key
points (p20-1). … Weight effect summary: TZD and SU
associated with weight gain, DPP4 inhibitors with
weight maintenance … , and GLP1 agonists and SGLT2
inhibitors with weight loss. … insulin with weight
gain? … We have added that insulin is
associated with weight gain.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label_executive.pdf
January 01, 2007 - Olanzapine caused significant weight gain in all
studies. … In two pooled
RCTs of dementia patients, olanzapine users were
6.12 times more likely to report weight … gain of 1.0,
0.7, and 0.4 pounds while on treatment, compared
to a weight loss among placebo-treated … Even greater weight gain
relative to placebo has been reported in trials of
non-elderly adults. … Mean weight
gain in the risperidone groups ranged from 2.1 kg
to 3.9 kg per study.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar-2010_research-protocol.pdf
January 01, 2010 - maintain normoglycemia without inducing
significant hypoglycemia, and to maintain normal/ideal body weight … risk for severer hypoglycemic episodes.
10
Finally, intensive insulin
therapy can also lead to weight … There was a statistically significant increase in mean birth weight associated with CSII when
compared … Weight gain
d. Hypoglycemia frequency
3. Clinical outcomes
a. … Weight gain associated with intensive therapy in the diabetes control and
complications trial.
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/pico-populations-breastfeeding-infants-6-months-or-less-with-ankyloglossia-interventions-frenotomy-frenectomy-or-frenulotomy-comparators-breastfeeding-management-without-surgical-intervention-outcomess-successful-exclusive-br
March 14, 2013 - breastfeeding with normalized suckle to swallow pattern), and increase in milk transfer leading to improved weight … untreated ankyloglossia in the breastfeeding infant may include problems with milk transfer leading to slow weight … approach to this problem is widely variable and many infants are weaned prematurely or have issues of weight
-
effectivehealthcare.ahrq.gov/products/diabetes-glucose-control/research
August 04, 2010 - non-inferiority relative to insulin glargine 10 and insulin aspart. 11 These trials also demonstrated weight … of individuals with obesity was highest in the group prescribed exenatide, an anticipated finding as weight … The known side-effect of weight loss could have motivated use of this medication, although we cannot … Long-term effects of exenatide therapy over 82 weeks on glycaemic control and weight in over-weight metformin-treated … Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-antenatal-care.pdf
April 01, 2021 - stress and
anxiety
Fetal/neonatal outcomes:
Mortality; morbidity (e.g. pre-term birth, low
birth weight … stress and
anxiety
Fetal/neonatal outcomes:
Mortality; morbidity (e.g. pre-term birth, low
birth weight … various approaches to telehealth-delivered antenatal
care, including remote patient monitoring of weight … Effect of Lifestyle Coaching Including Telemonitoring
and Telecoaching on Gestational Weight Gain and … Postnatal Weight Loss: A Systematic Review.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cer-215-depression-older-adults-executive-summary.pdf
March 01, 2019 - Seizures
• Serious adverse events
• Suicide/suicide attempt
• Suicidal thoughts
• SIADH/hyponatremia
• Weight … cognitive function, falls,
fracture, mortality, seizures, serious AEs, hyponatremia, suicide/
attempt, weight … fractures, mortality, serious
ADEAE, seizures, sodium/hyponatremia, suicidal thoughts, suicide/
attempt, weight … SSRI 2 RCTs10,20 Any AE, blood pressure, falls, fractures, mortality, serious AE, weight, withdrawal … SSRI 1 RCT22 Any AE, blood pressure, hospitalization, serious AE, weight, withdrawal due to AE
Trazodone
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-executive-summary.pdf
March 01, 2019 - Seizures
• Serious adverse events
• Suicide/suicide attempt
• Suicidal thoughts
• SIADH/hyponatremia
• Weight … cognitive function, falls,
fracture, mortality, seizures, serious AEs, hyponatremia, suicide/
attempt, weight … fractures, mortality, serious
ADEAE, seizures, sodium/hyponatremia, suicidal thoughts, suicide/
attempt, weight … SSRI 2 RCTs10,20 Any AE, blood pressure, falls, fractures, mortality, serious AE, weight, withdrawal … SSRI 1 RCT22 Any AE, blood pressure, hospitalization, serious AE, weight, withdrawal due to AE
Trazodone
-
effectivehealthcare.ahrq.gov/sites/default/files/ijzerman_ahrq-webinar-mcda.pdf
January 01, 2011 - Dia 1
1
Integrating stakeholder preferences in
comparative effectiveness research
using multi-criteria decision analysis
(MCDA) and Conjoint Analysis (CA)
Maarten J. IJzerman, PhD
Professor and chair, department Health Technology &
Services Research
m.j.ijzerman@utwente.nl
Multiple endpoints in …
-
effectivehealthcare.ahrq.gov/products/blood-clots-hip-knee-surgery/research-protocol
August 06, 2010 - pharmacologic agent within the defined classes (oral antiplatelet agents, injectable low molecular weight … Classes include oral antiplatelet agents, injectable low molecular weight heparins (LMWH), injectable … heparin versus low-molecular weight heparin plus compression stockings versus compression stockings) … cava filter
KQ
Key question
LDUH
Low density unfractionated heparin
LMWH
Low molecular weight … heparin OR low molecular weight heparin OR lmwh OR enoxaparin OR dalteparin OR nadroparin OR ardeparin
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gestational-diabetes-screening-diagnosis_research-protocol.pdf
December 16, 2011 - of developing diabetes later in
life.
6
Risks for the fetus include macrosomia (excessive birth weight … withdrawals, duration of followup), patient baseline
characteristics (e.g., age, race, ethnicity, weight … separately for subjective
outcomes (e.g., depression scales) and objective clinical outcomes (e.g., weight … will grade the following key outcomes: birth injury,
preeclampsia, neonatal hypoglycemia, maternal weight … Cesarean delivery in relation to
birth weight and gestational glucose tolerance: pathophysiology or
-
effectivehealthcare.ahrq.gov/health-topics/diabetes-0
August 04, 2010 - Systematic Review
Archived
November 5, 2010
Future Research Needs for Outcomes of Weight
-
effectivehealthcare.ahrq.gov/products/insulin-blood-sugar-2010/research-protocol
June 02, 2011 - maintain normoglycemia without inducing significant hypoglycemia, and to maintain normal/ideal body weight … at risk for severer hypoglycemic episodes. 10 Finally, intensive insulin therapy can also lead to weight … There was a statistically significant increase in mean birth weight associated with CSII when compared … * Fetal outcomes include gestational age, birth weight, frequency of neonatal hypoglycemia, birth … Weight gain associated with intensive therapy in the diabetes control and complications trial.
-
effectivehealthcare.ahrq.gov/products/bipolar-disorder-treatment/final-report-2018
August 07, 2018 - except for quetiapine, reported more extrapyramidal symptoms, and those on olanzapine reported more weight … extrapyramidal symptoms compared to placebo, and those using olanzapine reported more clinically significant weight
-
effectivehealthcare.ahrq.gov/products/diabetes-oral-drugs-safety-knowledge-gaps/research
January 01, 2005 - Glycemic and weight changes after persistent use of incident oral diabetes therapy: a Veterans Administration
-
effectivehealthcare.ahrq.gov/products/type-2-diabetes-medications-update/research-protocol
April 05, 2010 - morbidity and mortality. 1-3 Management of type 2 diabetes is complex and involves recommendations for weight … 2 for lists of comparisons) for the intermediate outcomes of glycemic control (in terms of HgbA1c), weight … Intermediate outcomes are glycemic control, serum lipid levels, weight, and blood pressure. … Intermediate outcomes are glycemic control, serum lipid levels, weight, and blood pressure. … For Key Question 1, we included the following outcomes: HgbA1c, weight, and serum lipid levels (HDL,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible.pdf
January 01, 2021 - true.9, 10 Hence, an important question to answer is whether carbohydrate
consumption influences body weight … 2 diabetes (T2D) and effect on growth, size, and body composition (i.e.,
obesity, overweight, body weight … have already
been diagnosed with the endpoint
outcomes of interest)
• Studies designed to induce weight … tolerance/insulin
resistance/insulin
sensitivity
• Growth, size, and body
composition
o Body weight … circumference
o Body composition and
distribution
o Classifications of
underweight, healthy
weight
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/binge-eating-disposition-160504.pdf
December 09, 2015 - In the
structured abstract you refer frequently to weight (whether or not
treatments would change weight … However, increasingly it has become clear that weight loss is
desirable for many patients with BED, … and that the ideal treatment
would usually incorporate weight loss effects. … relation to weight loss or reducing
binge-eating in the longer term" is a bit ambiguous. … We have revised the text to read Behavioral weight loss
treatment was superior to CBT for weight loss
-
effectivehealthcare.ahrq.gov/sites/default/files/s108.pdf
October 01, 2007 - time, given baseline severity, lagged severity, and time from
admission represented the unstabilized weight … The weight
was stabilized by using as the numerator the estimated prob-
ability of the individual’s observed
-
effectivehealthcare.ahrq.gov/products/meditation/research-protocol
October 17, 2012 - The review will also evaluate the effect of meditation programs on the clinical outcomes of pain and weight … of meditative programs on affect, attention, health-related behaviors affected by stress, pain, and weight … Question 4:
What are the efficacy and harms of meditation programs on pain and weight among those with … However, since weight is affected by multiple inputs including eating, weight will be evaluated as its … (body mass index and weight loss)
Harms (any noted by the study such as exacerbation of psychosis