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Total Results: 1,187 records

Showing results for "weeks".

241. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/13_pulmonary_potential_high_impact_june_2012.pdf
     January 01, 2012 - In trials, effects on pulmonary function were reported as early as 2 weeks, and a statistically significant … with placebo through week 24 (p<0.001). 5 Effects on pulmonary function were observed as early as 2 weeks … By 48 weeks, patients treated with ivacaftor had gained significantly more weight and secreted significantly … showed significant improvements in lung function and other measures of disease sustained through 48 weeks

242. CER 173 Executive Summary: Diabetes Medications for Adults With Type 2 Diabetes: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
     January 01, 2015 - †Based on studies with 104 weeks of followup. … An unpublished study (104 weeks of followup) and an unpublished longer term (156 weeks) followup of … A recent RCT with only 52 weeks of followup also found a higher risk of cancer in the DPP-4 inhibitor … We found low strength of evidence from published RCTs with 104 weeks of followup that the combination … A newer study with only 52 weeks of followup also corroborated the findings from the longer RCTs.

243. Gout Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive.pdf
     March 01, 2016 - also concluded, based on a comparison of the timing of the occurrence of acute gout attacks in the weeks … 13 ULT, that longer courses of prophylactic treatment with colchicine or NSAIDs (greater than 8 weeks … ) are more effective than courses of treatment with durations of 8 weeks or less, since in the one … 762, N=2,269, and N=1,072) High Longer durations of prophylaxis with colchicine or NSAIDs (> 8 weeks … when initiating urate lowering therapy with low-dose colchicine or NSAIDs should be longer than 8 weeks

244. Treatments for Fecal Incontinence: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_clinician.pdf
     July 01, 2016 - However, the median decrease in the number of FI episodes over 2 weeks was not significantly different

245. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pregnancy_hi_impact.pdf
     January 01, 2012 - Disease Control and Prevention indicate VLBW and extreme prematurity (infants born at fewer than 32 weeks … Disease Control and Prevention indicate VLBW and extreme prematurity (infants born at fewer than 32 weeks … At 37 weeks, a planned cesarean section is performed. 37 Adzick and colleagues (2011) presented … from a study of 183 patients whose fetus had spina bifida who either had prenatal surgery before 16 weeks

246. Dietary-Supplements Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_surveillance.pdf
     January 01, 2013 - Magnesium In a crossover trial of oral magnesium aspartate or placebo administered daily for 8 weeks … Echinacea Echinacea angustifolia root (600 mg) plus E. purpurea root (675 mg) qid, 2 weeks and a … American ginseng (P. quinquefolius 2 g/day from weeks 2 to 4) + warfarin: interactions unclear. … intermittent claudication (IC) and peripheral vascular disease (PVD) Treatment periods were 6 weeks … American ginseng (P. quinquefolius 2 g/day from weeks 2 to 4) + warfarin: interactions unclear.

247. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
     January 01, 2012 - mimic the effects of GI bypass surgery. 18 The device is intended to remain in place for 12–24 weeks … reported that implantation was successful in 26 of 30 patients; however, the device was removed after 12 weeks … study reported results of a study of 17 obese patients with T2DM who received EndoBarrier for 24 weeks

248. Disposition of Comments for Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
     April 25, 2013 - First, while it is true that it takes 2 weeks to make a red cell, it is not the case that after 2 weeks … therapy, the number of red cells produced is sufficient to increase the hematocrit; that takes four weeks … These have been changed to be consistent with the prescribing information stating 2 to 6 weeks. … , it is assumed for the analysis on page 96 that a 2 gm increase in hemoglobin will occur after 4 weeks … The guidelines also recommend discontinuation and not dose increase within a few weeks of therapy in

249. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
     January 01, 2012 - swallows the solution. 3 The company recommends a starting dose of 500 ova, taken orally once every 1–3 weeks … , with titration to a 1,000 ova per dose if no response is seen after 8 weeks (four treatments). 3 … The company notes that initial response may require several weeks and, because helminths are short-lived … After 24 weeks of treatment, 54% of patients treated with teduglutide were able to reduce the number … also be used to increase absorption of nutrients; however, somatropin has not been for longer than 4 weeks

250. Protocol Amendment - Safety of Vaccines 030413 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccines-safety-protocol-130325.pdf
     September 18, 2012 - Hepatitis A 12 months and older Hepatitis B Birth and older Hib (Haemophilus influenzae type b) 6 weeks … months and older Influenza (live attenuated) 2 years and older IPV (inactivated polio vaccine) 6 weeks … meningococcal polysaccharide vaccine) 2 years and older PCV13 (pneumococcal conjugate vaccine) 6 weeks … – 18 years Pneumococcal polysaccharide vaccine 2 years and older Rotavirus 6 weeks – 8 months Tdap

251. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea_research-protocol.pdf
     March 15, 2010 - • Multivariate analysis (probably) KQ 5-7 • Minimum duration: o Sleep clinical outcomes: 4 weeks … original sleep study; must be from a subsequent evaluation  Hemoglobin A1c and blood pressure: 4 weeks … o Compliance: 4 weeks (KQ 6 & 7: no minimum duration) o Adverse events: No minimum duration o Post-surgery … : minimum 6 weeks (except adverse events) • Prospective o Except surgical studies, where retrospective

252. Implementing Evidence-Based Screening and Counseling for Unhealthy Alcohol-Use With Epic-Based Electronic Health Record Tools: A Guide for Clinics and Health Systems Developed as Part of a Pilot Dissemination Project (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/implementation-package-unhealthy-alcohol-use-final.pdf
     September 01, 2018 - Screening • Printable Initial Alcohol Screen • Delay—Other clinical priorities (suppresses for 6 weeks … • DocFlowsheet: AUDIT • Printable AUDIT • Delay—Other clinical priorities (suppresses for 6 weeks … Add Problem (Alcohol use disorder (RAF-HCC) • Delay—Other clinical priorities (suppresses for 6 weeks

253. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1412.pdf
     January 01, 2015 - Significant HbA1c reductions observed over the 39 weeks of the study ranged from a “mean of 1.4% to … high baseline (HBL) study showed consistently maintained HbA1c level reductions of “3.4%” by 39 weeks … May 2013.63 They reported that HbA1c was significantly lower in all study groups after 12 and 24 weeks … Weight reductions were also observed—a loss of 2.8 to 3.7 kg (p<0.05) at 24 weeks in all except the … exenatide via DUROS device, leads to sustained improved glycemic control and weight loss for 48 weeks

254. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arthritis_hi_impact.pdf
     January 01, 2014 - with chronic gout were given pegloticase (8 mg) administered as a 2-hour IV infusion every 2 or 4 weeks … in patient-reported outcomes in pegloticase-treated patients who had received pegloticase every 2 weeks … duration; n = 261) were treated with three intra-articular injections of PRP administered every 2 weeks … fight infections. 83 Treatment with belimumab consists of an intravenous (IV) infusion every 4 weeks … and 76 weeks of belimumab therapy.

255. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - After 24 weeks, the device was removed from patients in the treatment group. … In 2012, Ponce and colleagues reported that after 24 weeks, the mean excess weight loss in the treatment … , which was 24 weeks after device removal, patients treated with ReShape Duo maintained 64% of their … assigned in a 2:1:1 ratio to receive 3 mg liraglutide, 1.8 mg liraglutide, or placebo.51 After 56 weeks … At 56 weeks, 69% of the prediabetes subgroup treated with liraglutide 3 mg no longer showed signs

256. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1506.pdf
     June 01, 2015 - ITCA 650 produced mean reductions in HbA1c of 1.4% at 39 weeks of treatment. … Weight loss over 39 weeks depended on drug dose, with patients who received 60 mcg/day losing a mean … of 4 kg at 39 weeks, compared with a 2 kg weight loss in the placebo group. … Weight loss over 39 weeks depended on drug dose. … They reported that HbA1c was significantly lower in all study groups after 12 and 24 weeks.

257. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - In trials, effects on pulmonary function were reported as early as 2 weeks, and a statistically significant … with placebo through week 24 (p<0.001).5 Effects on pulmonary function were observed as early as 2 weeks … By 48 weeks, patients treated with ivacaftor had gained significantly more weight and secreted significantly … showed significant improvements in lung function and other measures of disease sustained through 48 weeks

258. Behavioral Programs for Type 2 Diabetes Mellitus: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_clinician.pdf
     November 01, 2016 - programs that consist of repeated interactions with one or more trained individuals for a duration of ≥4 weeks

259. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1306.pdf
     January 01, 2016 - mg/dL [-38.4 mg/dL to -33.8 mg/dL]), and body weight (-2.5 kg [-2.8 kg to -2.3 kg]) after 24 to 30 weeks … metformin.47 Stage I of the study involved 155 subjects who were randomly assigned to receive 12 weeks … were achieved with 60 and 80 μg/day ITCA 650, and 86 and 78% of subjects achieved HbA1c ≤7% at 24 weeks … Weight was reduced by 2.8-3.7 kg (P < 0.05) at 24 weeks in all except the 20→20 μg/day group. … Benefit occurred for both doses compared with sham at 3 weeks and all subsequent time points.

260. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/11_peptic_ulcer_potential_high_impact_2012-12-111.pdf
     January 01, 2012 - The company recommends a starting dose of 500 ova, taken orally once every 1–3 weeks, with titration … to a 1,000 ova per dose if no response is seen after 8 weeks (4 treatments). … The company notes that initial response may require several weeks and, because helminths are short-lived … After 24 weeks of treatment, 54% of patients treated with teduglutide were able to reduce the number … to increase absorption of nutrients; however, somatropin has not been evaluated for longer than 4 weeks