-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_executive.pdf
January 01, 2014 - (KQs 1, 2, & 3)
Intermediate Outcomes
Wound healing at 4 weeks … standard definition of a chronic venous leg
ulcer, which is the presence of an active ulcer for 6 weeks … Patients must have had an active ulcer for at least 6 weeks. … We included studies with at least 4 weeks of
followup. … The
group that required more than 12 weeks to heal had 94
percent popliteal vein involvement.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fiber-intake-protocol.pdf
August 15, 2023 - bariatric surgery
• Those with acute illness or injury
• Pre-term babies (gestational age <37
weeks … • Observational studies
• All other study designs
Timing • Minimum duration of intervention:
2 weeks
-
effectivehealthcare.ahrq.gov/sites/default/files/13_pulmonary_potential_high_impact_2012-12-11.pdf
January 01, 2012 - In trials, effects on
pulmonary function were reported as early as 2 weeks, and a statistically significant … with placebo through week 24
(p<0.001).
5
Effects on pulmonary function were observed as early as 2 weeks … By 48 weeks, patients treated with ivacaftor had gained significantly more weight and
secreted significantly … showed significant improvements in lung function
and other measures of disease sustained through 48
weeks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_appendixes.pdf
January 01, 2006 - All
patients had at least one
endoscopic evaluation at 4,
8, 12 or 24 weeks. … Trial duration 4
weeks to 13 months. … Mean duration of trials was
22 weeks, with a range
from 6 days to 2 years. … If
outlier study (104 weeks)
removed, mean duration
was 5.8 weeks. … B
Patient global assessment (mean summary
score from weeks 1, 2, 3, and 4): 6.7 vs. 7.8 vs.
7.8
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fetal-surgery_disposition-comments.pdf
July 05, 2011 - intraluminal tracheal occlusion in a human
fetus with left congenital diaphragmatic hernia at 27
weeks … ,
iftemporary and before 26-28 weeks, typically do
notimpair lung development that much. … It is not uncommon
for the fetal surgery to be performed at 22-25 weeks,
preterm labor to occur at … 28 or 30 weeks resulting in a
cesarean delivery with two uterine procedures within a
month of each … Laser is rarely offered
after 26 weeks.
-
effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_june_2012.pdf
January 01, 2012 - The
company also reported the drug led to reduced body weight after 24 and 48 weeks of
treatment … Patients
received standard exenatide 5 mcg twice daily for 4 weeks followed by 10 mcg twice daily for … 20
weeks or exenatide extended release 2 mg once weekly. … for a
total of 48 weeks of treatment. … observed in HbA1c, fasting plasma
glucose, and weight across all treatment arms between 24 and 48 weeks
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_disposition-comments.pdf
January 01, 2015 - 52 weeks? 2 years? etc.) … Study
duration should be 26 weeks instead of 104 weeks. … We have changed the study duration to 26
weeks. … see reference 196 page 604
We have changed this to 26 weeks. … We agree that long term is not <52 weeks. This
terminology has been used for the last report.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertensive-disorders-pregnancy-disposition-comments.pdf
May 31, 2023 - 1,648)
was recruited at the time of prenatal screening for chromosomal
abnormalities (11+0 to 12+6 weeks … value of assessment of central
aortic systolic BP (cSBP), pulse wave velocity (PWV) and AIx at 11-13
weeks … Maternal
hemodynamics in normal pregnancies at 11-13 weeks’ gestation. … Arterial stiffness in normal pregnancy at11 13 weeks of
gestation and risk of late-onset hypertensive
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes_hi_impact.pdf
March 01, 2012 - The
company also reported the drug led to reduced body weight after 24 and 48 weeks of treatment. … Patients
received standard exenatide 5 mcg twice daily for 4 weeks followed by 10 mcg twice daily for … 20
weeks or exenatide extended release 2 mg once weekly. … , for a total of 48
weeks of treatment. … observed in HbA1c, fasting plasma glucose and weight
across all treatment arms between 24 and 48 weeks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
December 01, 2012 - Frequency
LHRH
Duration
LHRH
Descent (%)
Placebo
Descent (%)
Olsen et al., 1992
N = 123
4 weeks … Fair
400 µg 3 times daily 4 weeks 9.7 1.6a
De Muinck Keizer-Schrama et al. … and Hazebroek et al., 1986-87
N = 237
8 weeks
Poor
200 µg 3 times daily 4 weeks 9.0 8.0
Hagberg … and Westphal, 1982
N = 50
4 weeks
Poor
100 µg 3 times daily 28 days 62.0 3.0
Karpe et al., 1983 … N = 50
6 months
Poor
100 µg 6 times daily 28 days 20.0 12.0
Wit et al., 1986
N = 49
8 weeks
Poor
-
effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1506.pdf
November 01, 2016 - and Human
Development (NICHD), about half of stillbirths (i.e., miscarriages that occur after 20 weeks … However, these must be injected via a depot formulation, can take weeks to work,
and may induce menopause-like … However, these must be injected via a depot formulation, can take weeks to work, and may induce
menopause-like … However, peptide GnRH receptor
agonists must be injected via a depot formulation, can take weeks to
-
effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1512.pdf
November 01, 2016 - and Human Development (NICHD), about half of stillbirths (i.e., miscarriages that
occur after 20 weeks … However, these must be injected via a depot formulation, can take weeks to work,
and may induce menopause-like … However, these must be injected via a depot
formulation, can take weeks to work, and may induce menopause-like … However, peptide GnRH receptor
agonists must be injected via a depot formulation, can take weeks to
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
June 01, 2011 - case-control study) in which
26,170 patients receiving an ACEI or an ARB were followed
for periods from 12 weeks … to 5 years (median 24 weeks). … focusing on
direct renin inhibitors met our inclusion criteria, with the
longest followup being 36 weeks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
September 30, 2015 - Adverse Events and Withdrawals Due to Adverse Events Sponsor Quality
Hruschak, 2021 RCT
Duration: 6 weeks … , adjusted for race and depression)
Pain severity (0 to 10): 7.15 (SD 2.38) vs. 7.36 (SD 1.55) at 9 weeks … difference -0.21 (95% CI -1.71 to 1.29)*
Pain interference (0 to 70): 32.8 (SD 17.94) vs. 42.0 (10.71) at 9 weeks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
January 01, 2007 - case-control
study) in which 13,532 patients receiving an ACEI or an
ARB were followed for periods from 12 weeks … to 5 years
(median 16.5 weeks).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_consumer.pdf
January 01, 2017 - febuxostat (Uloric®).
» An NSAID or colchicine works best to lower this risk when
taken for longer than 8 weeks … attack, your health care professional may
suggest that you also take an NSAID or colchicine for several weeks
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_consumer.pdf
September 01, 2016 - If you try an antidepressant, you should take it for at least 8 weeks
to see if it will help. … A word about sticking with your treatment: Depression treatments may take several
weeks to start working
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix-E-Table-E5_0.xlsx
May 29, 2025 - , Median) Pain Duration, Months Psychiatric Comorbidity % N Interventions Dose Treatment Duration (Weeks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f5-table-surveillance-report-2_0_0.xlsx
May 29, 2025 - , Median) Pain Duration, Months Psychiatric Comorbidity % N Interventions Dose Treatment Duration (Weeks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - Randomized controlled trials (RCTs) of at least 6
weeks’ duration and in adult study populations were … Major Depressive Disorder
(KQ 1a)
Overall, 37 percent of patients did not respond during 6
to 12 weeks … The
NNT to gain 1 additional responder at 6 to 12 weeks
with sertraline was 13 (95% CI, 8 to 58). … The pooled NNT
to yield one additional responder after 1 or 2 weeks of
treatment is seven (95% CI, 5 … to 12); after 4 weeks of
treatment, however, most response rates were similar.