-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_surveillance.pdf
October 01, 2012 - RCT of a
less intensive DIR-based
developmental social pragmatic
(DSP) intervention (2 hours per
week … children w ASD
and anxiety-related
issues, aged 9 to 16
years
One 90 minute group
session per week … at
the center; 10h/week at
home
Children receiving EIBI showed
improvements in autism severity, … ABA
program Intensity: Two
30 minute sessions per
week, for 12 weeks
Tx group had greater play … in class, 4
hours per week
individual service
31% of children entering with
ASD were functioning
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
January 09, 2020 - ; 1 week to <2 weeks; 2 weeks to 4 weeks? … satisfaction, and quality of life after follow-up at the following intervals: < 1 day; 1 day to <1
week … ; 1 week to <2 weeks; 2 weeks to 4 weeks? … ; 1 week to <2 weeks; 2 weeks to 4 weeks? … ; 1 week to <2
weeks; 2 weeks to 4 weeks
None
7
PICOTS
Elements
Inclusion Criteria
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-rept-1-acute-pain.pdf
May 01, 2022 - tapentadol in pain at 1 day to <1
week, 1 to <2 weeks, or ≥4
weeks. … ; 1 week to less than 2 weeks; 2
weeks to less than 4 weeks; 4 weeks or longer? … ; 1 week to <2 weeks; 2 weeks to
less than 4 weeks; 4 weeks or longer? … ; 1 week to less
than 2 weeks; 2 weeks to less than 4 weeks; 4 weeks or longer? … ; 1 week to less than 2 weeks; 2
weeks to less than 4 weeks; 4 weeks or longer?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary_0.pdf
September 01, 2021 - corticosteroid injection for piriformis
syndrome may be similarly effective versus sham for pain at 1 week … with
large reductions in pain and moderate to large improvement in function versus usual
care at 1 week … No trial compared
kyphoplasty against sham (SOE: low for function at 1 week; moderate for pain and … piriformis syndrome associated with no difference versus local anesthetic alone in
pain at rest at 1 week … moderate reduction
in pain at rest versus local anesthetic at 1 month (SOE: low for no difference at 1
week
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-social-isolation-older-adults-final.pdf
February 01, 2019 - four interventions that found a positive effect on health or social isolation
met more than once per week … Of the same four studies, three
were high intensity, meeting more than once a week. … ), and two were medium-low intensity (met less than once a week or once a week,
depending on intervention … vs. twice a week). … Attended 4-5
meetings, for 1 hour roughly
every third week.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-appendix-b.xlsx
May 29, 2025 - Usual care: Approximately 20 to 25 hours of treatment per week including individual and group therapy … provide service delivery methods that offer more convenience and less burden Duration: Varied
Followup: Week … 6, Week 12, Week 24 Baseline variables, facility (long vs. short-term), substance use Days drank alcohol … Targeted discharge planning (16 week period) B. … No targeted discharge planning (previous 16 week period) A.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-3-acute-pain.pdf
June 01, 2022 - tapentadol in pain at 1 day to <1
week, 1 to <2 weeks, or ≥4
weeks. … sham TENS at 1 day to <1 week. … no difference at 1
day to <1 week (SOE: low,
based on 12 RCTs [<1 day]
and 3 RCTs [1 day to <1
week … ; 1 week to less than 2 weeks; 2
weeks to less than 4 weeks; 4 weeks or longer? … ; 1 week to <2 weeks; 2 weeks to
less than 4 weeks; 4 weeks or longer?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4-table-E-5.xlsx
January 01, 2023 - B
Mean mg/week at 3 month followup
THC: 93.29 (SD 228.12) vs. … B
Pain intensity index (VAS 0-100 scale) mean relative change (improvement) rates at week 24
83.4% vs … B
Pain-related disabilities (VAS 0-100 scale) mean relative change (improvement) rates at week 24
76.0% … B
Physical quality of life (VR12-PCS; NRS 100 scale) mean relative change (improvement) rates at week … Anxiety (DASS-A; NRS21) mean relative change (improvement) rates at week 24
78.4% vs. 52.3%, p<0.001
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-4-table-F5.xlsx
January 01, 2022 - B
Mean mg/week at 3 month followup
THC: 93.29 (SD 228.12) vs. … B
Pain intensity index (VAS 0-100 scale) mean relative change (improvement) rates at week 24
83.4% vs … B
Pain-related disabilities (VAS 0-100 scale) mean relative change (improvement) rates at week 24
76.0% … B
Physical quality of life (VR12-PCS; NRS 100 scale) mean relative change (improvement) rates at week … Anxiety (DASS-A; NRS21) mean relative change (improvement) rates at week 24
78.4% vs. 52.3%, p<0.001
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_technical-brief.pdf
January 01, 2020 - use the platform at a research or clinical facility required them to attend sessions
1-5 days per week … )
Gusi, 200621 Barefoot Not reported 3 days per
week, at least
1 day of rest in
between
sessions … )
Rubin, 200430 Unknown Yes 7 days per
week
48 No No bone
medications at
start
No 48
Russo … , 200352 Not reported Not reported 2 days per
week
24 No Not reported if
medications
taken
Yes … 8 No No bone
medications at
start
No 8
Ezenwa, 200873 Not reported Yes 3 times per
week
20
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
April 01, 2013 - One other trial of
24-week fixed duration triple therapy with telaprevir,
pegylated interferon alfa … Among
patients randomized to the 24-week telaprevir regimen, one
to two-thirds experienced a rash ( … 4 SVR, HCV RNA seronegative by PCR
throughout 24-week off-treatment period
Safety - adverse event … Versus 48-Week
Courses of Peginterferon
Plus. … Boceprevir
Pegylated interferon alfa-2b
Ribavirin
Adult
Senior
Efficacy
Week 8 response
Week
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_surveillance.pdf
December 01, 2015 - Original Search Strategy
Database: Ovid MEDLINE(R) and Ovid OLDMEDLINE(R) <1946 to June Week 4 2015 … telaprevir vs. 12 week teleprevir regimen:
•! … Higher BMI
24-week fixed duration triple therapy with telaprevir, pegylated interferon alfa-2b, and … telaprevir vs. 12 week teleprevir
regimen:
•! … alfa-2b (1.5 µg/kg/week; n=259)
with ribavirin (800–1200
•!
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_surveillance.pdf
December 01, 2015 - Original Search Strategy
Database: Ovid MEDLINE(R) and Ovid OLDMEDLINE(R) <1946 to June Week 4 2015 … telaprevir vs. 12 week teleprevir regimen:
•! … Higher BMI
24-week fixed duration triple therapy with telaprevir, pegylated interferon alfa-2b, and … telaprevir vs. 12 week teleprevir
regimen:
•! … alfa-2b (1.5 µg/kg/week; n=259)
with ribavirin (800–1200
•!
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-draft-appendix-d2.xlsx
January 01, 2024 - avoid potential excessive acute toxic effects in the hypofractionation group, only three fractions per week … Patients received five daily fractions of 2 Gy a week (overall treatment time about 8 weeks)…Three treatment … IG1 IG1 62 20 3.1 MHF 5 Moderate hypofractionation 62 Gy in 20 fractions in 5 weeks (4 fractions per week … The UHF arm was treated once a week for 5 fractions over 5 weeks to a total dose of 36.25 Gy…The PTV … Daily radiation therapy 5 times a week was delivered to the PTV in 28 fractions to a total dose of 70
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-summary.pdf
August 01, 2023 - Executive Summary: Radiation Therapy for Metastatic Bone Disease: Effectiveness and Harms
Comparative Effectiveness Review
Number 265
Radiation Therapy for Metastatic Bone
Disease: Effectiveness and Harms
Executive Summary
Main Points
Background and Purpose
Bone metastases are common in advan…
-
effectivehealthcare.ahrq.gov/sites/default/files/fraenkel.pdf
May 29, 2025 - Four
individual bar
charts
captioned:
Infusion 1x/year;
Exercise
3x/week;
1 pill … 1x/week; none.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-evidence-summary.pdf
August 01, 2018 - placebo
3 RCT13-15
(n=1,047)
3
week
Response Rate: Favors Cariprazine, OR 2.14 (95% CI 1.08, … A 3-week, randomized,
placebo-controlled trial of asenapine in the treatment of acute
mania in bipolar … Acute and
continuation risperidone monotherapy in bipolar mania: a 3-week
placebo-controlled trial … followed by a 9-week double-blind trial
of risperidone and haloperidol. … Ziprasidone in the
treatment of acute bipolar mania: a three-week, placebo-
controlled, double-blind
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-protocol-acute-pain-treatments.pdf
August 08, 2019 - ; 1 week to less than 2 weeks; 2 weeks to less than 4 weeks; 4 weeks
or longer? … ; 1 week to <2 weeks; 2 weeks to less than 4 weeks; 4 weeks or
longer? … and no treatment after followup at the
following intervals: less than 1 day; 1 day to less than 1 week … ; 1 week to less than 2 weeks; 2
weeks to less than 4 weeks; 4 weeks or longer? … ; 1 week to less than 2 weeks; 2 weeks to less than 4 weeks; 4 weeks
or longer?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-surveillance-150120.pdf
October 01, 2014 - RESULTS: Nearly 50% of the PANSS decrease was achieved by week 2 and up to 75% by week 3. … [DSM-IV]) were enrolled in a 6 week, randomized, double-blind, placebo-controlled multicenter trial ( … RCT)
followed by a 26 week open-label extension study (OLE). … 1), EMBASE
(1980 to 2011 Week 32), PsycINFO (1806 to August Week 2 2011), CINAHL (1937 to current), … METHODS: This study was a post-hoc analysis of pooled data from two 8-week, double-blind,
randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1512.pdf
January 28, 2016 - Additionally, Harvoni may now be used with RBV in a 12-
week treatment regimen in patients with HCV … The cost of a 4-week supply of
generic RBV (1,000 mg) is about $500. … The cost of a 4-week supply of IFN is about $3,500. … Daklinza/Sovaldi costs about $147,000 for a 12-week course. … The retail cost of a 12-week regimen of Viekira Pak is about
$89,000;76 the retail cost of a 12-week