-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer--brca-testing-ovarian-cancer-screeni
September 15, 2005 - germline mutation carriers at prophylactic oophorectomy: a case for recommending hysterectomy at surgical prophylaxis … using estrogen
Tamoxifen, 3573;
placebo, 3566
50
Total
69
101
0.68 (0.50-0.92)
VTE … using estrogen
Tamoxifen, 1238;
placebo, 1233
70
Total
34
36
0.94 (0.59-1.49) **
VTE … using estrogen
Tamoxifen, 2700;
placebo, 2708
46
Total
19
22
0.87 (0.47-1.60) **
VTE … estrogen receptor; NA = not available; NS = not statistically significant; PE = pulmonary embolism; VTE
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-and-ovarian-cancer-brca-testing-screening-2005
September 15, 2005 - germline mutation carriers at prophylactic oophorectomy: a case for recommending hysterectomy at surgical prophylaxis … using estrogen
Tamoxifen, 3573;
placebo, 3566
50
Total
69
101
0.68 (0.50-0.92)
VTE … using estrogen
Tamoxifen, 1238;
placebo, 1233
70
Total
34
36
0.94 (0.59-1.49) **
VTE … using estrogen
Tamoxifen, 2700;
placebo, 2708
46
Total
19
22
0.87 (0.47-1.60) **
VTE … estrogen receptor; NA = not available; NS = not statistically significant; PE = pulmonary embolism; VTE
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/3HxQuXnyqHpUKNqjB7hWBw
September 01, 2005 - estrogen receptor; NA � not available; NS � not statistically significant; PE � pulmonary embolism; VTE … 11 1.18 (0.53–2.63)†
Endometrial cancer 11 5 2.2 (0.86–6.06)
All-cause death 25 11 2.27 (1.12–4.60)†
VTE … 1.59 (0.93–2.77)†
Endometrial cancer 36 15 2.53 (1.35–4.97)
All-cause death 57 71 0.81 (0.56–1.16)†
VTE … 0.50–8.01)†
Stroke 9 5 1.81 (0.61–5.38)†
Endometrial cancer NA
All-cause death 6 9 0.67 (0.24–1.88)†
VTE … germline mutation carriers at
prophylactic oophorectomy: a case for recommending hysterectomy at surgical
prophylaxis
-
www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/breast-cancer-medications-for-risk-reduction
September 03, 2019 - ) events, or stroke. 3
When compared with placebo, raloxifene was associated with 7 more cases of VTE … on the STAR trial, more harms were reported with tamoxifen compared with raloxifene: 4 more cases of VTE … Long-term results of tamoxifen prophylaxis for breast cancer—96-month follow-up of the randomized IBIS-I
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction
September 03, 2019 - ) events, or stroke. 3
When compared with placebo, raloxifene was associated with 7 more cases of VTE … on the STAR trial, more harms were reported with tamoxifen compared with raloxifene: 4 more cases of VTE … Long-term results of tamoxifen prophylaxis for breast cancer—96-month follow-up of the randomized IBIS-I
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/3Kwu7j_WfCFQSnSzqrDWwt
June 20, 2019 - CHD) events, or stroke.3
When compared with placebo, raloxifene was associated with
7 more cases of VTE … on the STAR trial, more harms
were reported with tamoxifen compared with raloxifene: 4 more
cases of VTE … Long-term results of tamoxifen prophylaxis for
breast cancer—96-month follow-up of the
randomized IBIS-I
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction-2013
September 15, 2013 - general, women taking medications for breast cancer risk reduction are less likely to experience a VTE … Women with a personal or family history of venous thromboembolism are at higher risk for these adverse … Long-term results of tamoxifen prophylaxis for breast cancer—96-month follow-up of the randomized IBIS-I
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/zVVRY6wa4Sgj-EJb3BRcVy
November 01, 2013 - Effects
In general, women receiving medications for breast
cancer risk reduction are less likely to have VTE … Women with a personal or family history of
venous thromboembolism are at higher risk for these ad-
verse … Long-term re-
sults of tamoxifen prophylaxis for breast cancer—96-month follow-up of the
randomized IBIS-I
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer-medications-for-risk-reduction
September 03, 2019 - Long-term results of tamoxifen prophylaxis for breast cancer—96-month follow-up of the randomized IBIS-I … with tamoxifen
0.97 (0.86-1.12)
2
NA
NA
1.05 (0.87-1.28)
2
NA
NA
Harms
Venous … thromboembolism j
0.75 (0.60-0.93) d
4 (1-7) more with tamoxifen
1.93 (1.33-2.68)
4
0.91 ( … Project; PE, pulmonary embolism; RR, risk ratio; RUTH, Raloxifene Use for the Heart; SE, standard error; VTE … , venous thromboembolism.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/-TsBkyewVoFpC7htRmzWJa
September 03, 2019 - Project; PE, pulmonary embolism; RR, risk ratio; RUTH, Raloxifene Use for the
Heart; SE, standard error; VTE … , venous thromboembolism.
a Numbers of events reduced for benefits or increased for harms vs comparator … Long-term results of tamoxifen prophylaxis for
breast cancer—96-month follow-up of the
randomized IBIS-I