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  1. Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease: Future Research Needs (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia_research.pdf
    January 01, 2013 - cell volume distribution, for diagnosing adult patients with iron deficiency, but test performances varied

  2. Screening and Diagnosing Gestational Diabetes Mellitus Disposition of Comments Report (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_disposition-comments.pdf
    January 01, 2020 - Peer Reviewer #4 General This review is comprehensive and does a good job summarizing the varied … screens and blood glucose thresholds and the varied populations in which this has been studied.

  3. Hi Les, (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/rtc-design-principles_research.pdf
    January 01, 2009 - Hi Les, Medical Tests—White Paper Series Using the Principles of Randomized Controlled Trial Design To Guide Test Evaluation The findings and conclusions in this document are those of the authors, who are responsible for its contents; the findings and conclusions do not necessarily represent t…

  4. Ch 5-User-Guide-To-Ocer 130129 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
    January 01, 2012 - 59 Abstract This chapter discusses considerations for comparator selection in observational comparative effectiveness research (CER). Comparison groups should reflect clinically meaningful choices in real world practice and be chosen based on the study question being addressed. Recognizing the implications and pote…

  5. Assessing the Quality of Individual Studies (ppt file)

    effectivehealthcare.ahrq.gov/sites/default/files/assessing-quality.ppt
    January 01, 2010 - Different institutions may use the word “quality” for varied purposes.

  6. Diagnosis and Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-fatigue_executive.pdf
    July 01, 2016 - Diagnosis and Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Evidence-Based Practice Evidence-based Practice Program The Agency for Healthcare Research and Quality (AHRQ), through its Evidence- based Practice Centers (EPCs), sponsors the development of evidence reports and technology assessme…

  7. Menopause Executive (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
    March 01, 2015 - 1 Menopausal Symptoms: Comparative Effectiveness of Therapies Executive Summary Background Menopause is defined as the permanent cessation of menstruation and ovulation due to ovarian failure. “Spontaneous” menopause occurs after 12 months of amenorrhea as ovarian hormone secretion diminishes, on average aroun…

  8. Diagnosis of Celiac Disease: Current State of the Evidence (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_clinician.pdf
    July 01, 2016 - individual tests—was rarely clinically significant because the sensitivity and specificity results varied

  9. Comparative Effectiveness of Coronary Bypass Surgery and Percutaneous Coronary Interventions for Multivessel Disease: A Pooled Analysis of Individual Patient Data from Ten Randomized Trials (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_addendum.pdf
    February 01, 2010 - Since length of follow-up varied among the trials, we tested for any differences in the hazard ratio … Median follow-up time in surviving patients was 5.9 years and varied among trials from 3.0 years to

  10. AHRQ Evidence-based Practice Center Program Research Gaps Summary: Telehealth (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ehc-research-gaps-telehealth.pdf
    April 01, 2023 - staffing models), ideally using implementation frameworks, and generate evidence from organizations with varied

  11. CER 210: Disposition of Comments for Breastfeeding Programs and Policies, Breastfeeding Uptake, and Maternal Health Outcomes in Developed Countries (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-210-breastfeeding-disposition-comments.pdf
    January 01, 2020 - quasi-experimental” is potentially misleading; this study evaluated outcomes among cohorts of hospitals that varied … present an analysis of how the effect of interventions on breastfeeding prevalence has or has not varied … For overall breast cancer, magnitude and direction of effect varied by breastfeeding duration; for any

  12. Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: Final Update of a Rapid, Living Review (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19.pdf
    December 31, 2022 - Second, reporting varied widely across studies.

  13. Psychosocial and Pharmacologic Interventions for Disruptive Behavior in Children and Adolescents (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-protocol.pdf
    January 31, 2023 - Psychosocial and Pharmacologic Interventions for Disruptive Behavior in Children and Adolescents Evidence-based Practice Center Systematic Review Protocol Project Title: Psychosocial and Pharmacologic Interventions for Disruptive Behavior in Children and Adolescents I. Background and Objectives for t…

  14. Breastfeeding and Health Outcomes for Infants and Children (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol.pdf
    February 01, 2023 - Breastfeeding and Health Outcomes for Infants and Children Evidence-based Practice Center Systematic Review Protocol Project Title: Breastfeeding and Health Outcomes for Infants and Children I. Background and Objectives for the Systematic Review Breastfeeding – the feeding of human milk at the breast or exp…

  15. Disposition of Comments Report for Imaging Techniques for the Diagnosis and Staging of Hepatocellular Carcinoma (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_disposition-comments.pdf
    October 23, 2014 - Diagnostic criteria (reference standards) varied between trials from explanted liver examination to … variability in the scales (e.g. 1-5, 1- 4, 1-3, or other) and the cutoffs applied for a positive diagnosis varied … (MITA) General Our comments address three areas in the Draft Report: (1) imaging modalities have varied … Public Reviewer Gail Rodriguez (MITA) General 1) Imaging modalities have varied functions and uses

  16. Evidence-based Practice Center Systematic Review Protocol (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/genitourinary-symptoms-protocol_0.pdf
    July 10, 2023 - Physical changes and signs are varied and include labial atrophy, vaginal dryness, introital stenosis

  17. Respectful Maternity Care: Dissemination and Implementation of Perinatal Safety Culture to Improve Equitable Maternal Healthcare Delivery and Outcomes (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/respectful-maternity-care-protocol.pdf
    September 16, 2022 - Respectful Maternity Care: Dissemination and Implementation of Perinatal Safety Culture to Improve Equitable Maternal Healthcare Delivery and Outcomes Evidence-based Practice Center Systematic Review Protocol Project Title: Respectful Maternity Care: Dissemination and Implementation of Perinatal Safety Cu…

  18. Maternal Morbidity and Mortality (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/mmm-draft-protocol-amendment.pdf
    February 02, 2022 - Maternal Morbidity and Mortality Evidence-based Practice Center Systematic Review Protocol Project Title: Maternal Morbidity and Mortality Initial Publication Date: December 9, 2021 Amendment Date: February 2, 2022 (Amendments Details–see Section VII) I. Background Maternal morbidity descr…

  19. Treatments for Schizophrenia in Adults: A Systematic (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
    January 01, 2017 - Controls described as “active” varied widely, from competing interventions to attention controls, and … The specific characteristics of patients varied somewhat by intervention category.

  20. Hepatitis-C Executive (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
    November 01, 2012 - Relative risk estimates ranged from 1.01 to 1.33 in the four trials and may have varied in part due … or presence of HCV-RNA from weeks 4 through 20) found similar SVR rates (81–85%) for regimens that varied
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