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effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
October 01, 2011 - complications (RR 0.23, 95% CI 0.07 to 0.76)
and ulcer complications or symptomatic ulcers (RR
0.39, … complications or
symptomatic ulcers at 6-month followup (2.1% vs.
3.5%, p=0.02), but not at 12-month … complications or symptomatic ulcers compared to
various nonselective NSAIDs in 6 trials included in … Coprescribing of misoprostol was associated with a
lower risk of endoscopically detected gastric ulcers … compared to ranitidine, and a similar reduction in risk
of endoscopically detected duodenal ulcers.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/skin-substitute_0.pdf
October 03, 2019 - Chronic wounds include pressure ulcers,
diabetic foot ulcers, and venous leg ulcers. … For diabetic foot ulcers, failure to show more
than 50% wound area reduction in 4 weeks, indicates the … Are there some basic treatments that should constitute standard of care for specific ulcer
types (e.g … ., pressure off-loading or debridement for diabetic foot ulcers, compression
bandages for venous ulcers … , diabetic foot ulcer, venous leg
ulcer, or arterial leg ulcer) lasting more than 30
days without healing
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effectivehealthcare.ahrq.gov/products/skin-substitutes/protocol
November 27, 2018 - Chronic wounds include pressure ulcers, diabetic foot ulcers, and venous leg ulcers. … For diabetic foot ulcers, failure to show more than 50% wound area reduction in 4 weeks, indicates the … Are there some basic treatments that should constitute standard of care for specific ulcer types (e.g … ., pressure off-loading or debridement for diabetic foot ulcers, compression bandages for venous ulcers … , diabetic foot ulcer, venous leg ulcer, or arterial leg ulcer) lasting more than 30 days without healing
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effectivehealthcare.ahrq.gov/sites/default/files/mcda-johnson.pdf
August 27, 2012 - Serious Side-Effect Risks--
RISK OF BLEEDING
ULCER
1 patient out of 100 (1%)
will have a bleeding … ulcer.
5 patients out of 100 (5%)
will have a bleeding ulcer.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/nursing-home-safety_research-protocol.pdf
July 22, 2015 - practices of obvious relevance to non-acute settings include the
literature about fall and pressure ulcer … , double-blind
cross-over trial in patients prone to pressure ulcers. … Turning for Ulcer ReductioN: a multisite
randomized clinical trial in nursing homes. … Pressure Ulcer Prevention Program Study: a randomized,
controlled prospective comparative value evaluation … of 2 pressure ulcer prevention strategies in nursing and
rehabilitation centers.
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effectivehealthcare.ahrq.gov/products/nursing-home-safety/research-protocol
July 30, 2015 - practices of obvious relevance to non-acute settings include the literature about fall and pressure ulcer … , double-blind cross-over trial in patients prone to pressure ulcers. … Turning for Ulcer ReductioN: a multisite randomized clinical trial in nursing homes. … Pressure Ulcer Prevention Program Study: a randomized, controlled prospective comparative value evaluation … of 2 pressure ulcer prevention strategies in nursing and rehabilitation centers.
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effectivehealthcare.ahrq.gov/products/diabetic-neuropathy/research-2017
March 24, 2017 - Messages
Intensive glycemic control is not more effective than standard control for preventing foot ulcers … skin temperature, therapeutic footwear, and integrated foot care are effective for preventing foot ulcers … bias of the reviews and studies, and graded the strength of evidence (SOE) for critical outcomes (foot ulcers … of surgical interventions (low SOE) are effective for lowering incidence and/or recurrence of foot ulcers … footwear, and integrated interventions are effective for preventing incidence and/or recurrence of foot ulcers
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effectivehealthcare.ahrq.gov/health-topics/u
Home »
Health Topics »
Health Topics: U
Health Topics: U
Ulcerative Colitis
Ultrasound
Understanding Medical Research
Urethral Disorders
Urinalysis
Urinary Incontinence
Urinary Tract Infections
Urine and Urination
Uterine Diseases
Uterine Fibroids
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetic-neuropathy_research-protocol.pdf
May 09, 2016 - Ulcers and infections may eventually lead to amputation of the lower extremities. … There was some
evidence to suggest that prevention of a recurrent foot ulcer by integrated foot care … well as usual care/placebo
Outcome(s):
• Benefits (KQ1a and KQ1b):
o Incident or recurrent foot ulcer … outcomes were
identified as critical
outcomes to be graded
for the strength of
evidence: foot ulcer … and amputation
Based on the feedback
from AE and TOO, foot
ulcer and amputation
outcomes have
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0658-140831.pdf
July 19, 2014 - peripheral neuropathy is associated with chronic pain, limited mobility, development of sores and
ulcers … include pharmaceuticals, acupuncture, electrical nerve
stimulation, and treatment of open wounds and ulcers
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effectivehealthcare.ahrq.gov/health-topics/stomach-disorders
May 20, 2013 - with Gastroprotective Therapy
Research Report
December 2, 2009
Chronic Venous Ulcers
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-disposition-120516.pdf
October 01, 2011 - We only considered rates of endoscopic ulcers when data on
clinical ulcer complications were incomplete … There was no difference in rates of ulcer
complications or symptomatic ulcers at either 6
month or … The second sentence should have referred only to ulcer
complications (i.e. without symptomatic ulcers … or ulcer
complications (see Table A, KQ 1A, GI and CV harms: Partially
selective NSAIDs, page 17). … PPIs are superior to misoprostol for
duodenal ulcers and equivalent for gastric ulcers).
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/pico-1-populations-children-with-infantile-hemangiomas-ihs-interventions-early-referral-comparators-delayed-referral-outcomess-minimization-of-functional-impairment-andor-cosmetic-deformity-pico-2-populations-children-with
November 14, 2013 - Home »
Get Involved »
Nominated Topics »
Topic Suggestion Description
Topic Suggestion Description
Date submitted: November 14, 2013
Download Topic Suggestion Disposition [PDF · 1.2 MB]
Briefly describe a specific question, or set of related questions, about a health…
-
effectivehealthcare.ahrq.gov/sites/default/files/s50.pdf
October 01, 2007 - Practice-Based Evidence for Clinical Practice
Improvement in Long-term Care
The National Pressure Ulcer … records of 1524 residents (from 95
long-term care facilities) who were at risk for developing
pressure ulcers … No resident started with a pressure ulcer, but
29% of residents developed one by the end of the 12-week … interventions were determined by the NPULS
and were implemented consistently, development of new
pressure ulcers … The National Pressure Ulcer
Long-Term Care Study: pressure ulcer development in long-term care
residents
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_appendixes.pdf
January 01, 2006 - ulcers
RA with flare and no
ulcer on EGD
100,
200, or
400 bid
naproxen 500 bid 918 12
Emery … endoscopic ulcers RA 200 bid diclofenac 75 bid 655 24
Silverstein
(CLASS)
serious GI events OA … OA with no ulcer on
EGD
25 ibuprofen 800 tid 581 18
Laine (044) endoscopic ulcers OA with no ulcer … Two diclofenac patients required hospitalization due to gastric erosions/ulcer. … Fewer duodenal
ulcers at 25mg RR 0.24 CI: 0.09, 0.63 but no SS difference
at 50mg.
-
effectivehealthcare.ahrq.gov/products/venous-ulcers-treatment/
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
January 01, 2006 - • Coexisting diseases include hypertension,
edema, ischemic heart disease, heart failure;
peptic ulcer … nonselective NSAID
• In the only large, long-term trial (VIGOR),
rofecoxib 50 mg daily caused fewer serious
ulcer … only
large, published trial (CLASS), celecoxib at
800 mg daily did not decrease predefined
serious ulcer … patients who had a recent episode of upper
GI bleeding, there is good evidence that rates of
recurrent ulcer … Concomitant aspirin use
• In the CLASS studies, there was no difference in
rates of ulcer complications
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effectivehealthcare.ahrq.gov/health-topics/colonic-diseases
April 02, 2014 - Infection Update
Research Protocol
Archived
December 23, 2014
Chronic Venous Ulcers
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/diagnosis-and-management-pressure-ulcer-the-questions-we-would-like-answered-by-this-evidence-review-are-the-following-1-how-can-we-identify-patients-at-risk-for-pressure-ulcers-in-the-hospital-or-long-term-care-setting-and-
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_research-protocol.pdf
December 23, 2014 - mh] OR pain[tiab] OR “Skin atrophy”[tiab] OR venous
prominence[tiab] OR facial injuries[mh] OR skin ulcer