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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/vision-in-children-ages-6-months-to-5-years-screening
December 17, 2015 - For children with amblyopia, its risk factors, or refractive error, treatment may improve health outcomes … Treatment may also result in harms (key question 5). … Does treatment of amblyopia, its risk factors, and refractive error in children ages 6 months to 5 years … What are the harms of treatment of amblyopia, its risk factors, and refractive error in children ages … refractive error (eyeglasses); penalization of the nonamblyogenic eye (eye patch, atropine); and vision therapy
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/update-methods-insufficient-evidence
March 04, 2021 - delivery in a "gold-standard" RCT may eliminate the contextual aspects of the treatment experience and … the adaptation of treatment to individual needs that underlies treatment success. … Requiring a no-treatment or usual-treatment control condition may produce insurmountable barriers to … of the clinician-patient relationship with respect to building trust and developing a collaborative therapeutic … prevents, the burdens of the therapy, the monetary costs of the therapy, and the guideline developers
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/syphilis-infection-screening-1996
January 01, 1996 - Antibiotic therapy with penicillin G benzathine (or tetracycline hydrochloride if neurosyphilis has been … to the fetus of acquiring congenital syphilis. 9 Prenatal antibiotic therapy is effective in preventing … erythromycin, an antibiotic with limited efficacy in preventing congenital syphilis, or if antibiotic therapy … Syphilis tests in diagnostic and therapeutic decision making. … Syphilis tests in diagnostic and therapeutic decision making. In: Sox HC Jr, ed.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/qVACAf9sMmuX48MnnVDcBR
July 01, 2004 - Antibiotic therapy is highly effective in
eliminating T. pallidum and in preventing
congenital infection … .13–16 Little evidence
is available to guide therapy in pregnancy. … No studies have directly looked at the harms of
screening or treatment. … reaction with headache, myalgia,
and other symptoms) that may occur within the
first 24 hours after any therapy … Treatment of syphilis with azithromycin.
Int J STD AIDS. 1996;7(1):13–15.
17.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/syphilis-infection-screening-2004
July 15, 2004 - Antibiotic therapy is highly effective in eliminating T. pallidum and in preventing congenital infection … . 13-16 Little evidence is available to guide therapy in pregnancy. … No studies have directly looked at the harms of screening or treatment. … reaction with headache, myalgia, and other symptoms) that may occur within the first 24 hours after any therapy … Treatment of syphilis with azithromycin. Int J STD AIDS 1996;7(1):13-5.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/preeclampsia-screening-april-2017
April 25, 2017 - Benefits of Early Detection and Treatment
Preeclampsia is a complex syndrome. … The USPSTF found adequate evidence that the well-established treatments of preeclampsia result in a substantial … of screening for and treatment of preeclampsia as no greater than small. … This assessment was based on the known harms of treatment with antihypertension medications, induced … improving health outcomes, trial evidence and extensive clinical experience provide evidence of effective treatments
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary1/osteoporosis-screening-june-2018
June 26, 2018 - Pharmacologic treatments for osteoporosis inhibit osteoclastic bone resorption (antiresorptive agents … Eligible treatments included US Food and Drug Administration (FDA)–approved pharmacotherapy (specifically … Benefits of Treatment
Key Question 4a. … Bone modeling and remodeling: potential as therapeutic targets for the treatment of osteoporosis. … Fracture risk and zoledronic acid therapy in men with osteoporosis.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review86/rh-d-incompatibility-screening
February 15, 2004 - fetal anemia in pregnancies complicated by Rh (D) incompatibility. 2 , 3
Key Question 3: Have new treatment … We found no RCTs with direct evidence addressing new treatment protocols developed and tested to show … Key Questions 4 and 5: Have new harms been identified for screening or treatment
of Rh (D) incompatibility … no RCTs with direct evidence identifying either new or stronger harms associated with screening or treatment
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/YSj5xRQc9DroH8gpUYsoFA
December 01, 2007 - for RCTs, systematic
reviews, and meta-analyses that compared carotid endarter-
ectomy with medical therapy … angiographically confirmed CAS 60% or greater
for random allocation to carotid endarterectomy or medi-
cal therapy … The treatment groups did not statistically signifi-
cantly differ in all-cause mortality. … It is
difficult to determine what effect current standard medical
therapy would have on overall benefit … The use of current medical therapy could have
reduced the stroke rate in the medical treatment group
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www.uspreventiveservicestaskforce.org/uspstf/document/how-did-the-uspstf-arrive-at-this-recommendation-/prostate-cancer-screening-2012
May 11, 2012 - with surgery, radiation, or hormone therapy. … even without treatment. … harms:
Erectile dysfunction (impotence) from surgery, radiation therapy, or hormone therapy;
Urinary … incontinence (leakage of urine) from radiation therapy or surgery;
Problems with bowel control from … radiation therapy; and
Death and serious complications from surgery.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan97/breast-cancer-screening-january-2016
July 17, 2014 - carcinoma in situ, atypical ductal or lobular hyperplasia); or previous large doses of chest radiation therapy … carcinoma in situ, atypical ductal or lobular hyperplasia); or previous large doses of chest radiation therapy … density, parity, race/ethnicity, age at first birth, menopausal status, current use of menopausal hormone therapy … situ, atypical ductal or lobular hyperplasia); or women with previous large doses of chest radiation therapy … adverse effects of treatment, quality of life measures, other measures of impairment).
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/QTkyWhfQHqFUy4He2B6HU4
Pacific Islander participants, to investigate whether the effectiveness of screening, diagnosis, and treatment … KQ1: Breast cancer morbidity
(e.g., adverse effects of
treatment and no treatment,
physical/functional … and contrast-
enhanced
mammography) or
KQ1: Breast cancer
morbidity (e.g., adverse
effects of treatment … Research is needed to understand how
variations in care (including diagnosis and
treatment) leads to … Breast cancer morbidity (e.g.,
adverse effects of treatment,
physical/functional
impairment).
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/cardiovascular-disease-screening-using-nontraditional-risk-assessment
July 10, 2018 - Treatments and Interventions
Asymptomatic adults at increased risk for CVD are usually treated with … Two RCTs (total N = 4626) compared using the ABI to guide decisions to start aspirin therapy vs usual … the effect of screening with CAC score on risk perception, adherence to medication, and behavioral therapies … Some comments also expressed belief that CAC score testing leads to better adherence to preventive therapies … It recommends judicious use of secondary testing among patients for whom the need for statin therapy
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary24/falls-prevention-in-older-adults-counseling-and-preventive-medication-2012
December 15, 2010 - For single clinical treatments, the analyses were further stratified by treatment type. … Exercise or Physical Therapy
We evaluated 18 trials of exercise or physical therapy interventions ( … Single Clinical Treatments
Vitamin D
We evaluated 9 trials of vitamin D supplementation (5809 participants … Other treatments for uncorrected refractive errors showed limited evidence of harm. … Management approaches were categorized as comprehensive (treatments and education to comprehensively
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www.uspreventiveservicestaskforce.org/uspstf/update-on-methods-insufficient-evidence---table-6
February 01, 2009 - Pharmacologic treatment of high blood pressure has side effects. … The potential long-term harms of pharmacologic treatment of high blood pressure when started at a young
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan11/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing-2013
December 15, 2012 - any point during the risk assessment and testing process, as well as with preventive interventions or treatment … Treatment or Management Interventions (KQs 4–5)
Studies of interventions to reduce risk for BRCA-related … KQs 4 and 5: Treatment/intervention versus no treatment/intervention, placebo, or other treatment/intervention
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/T-DyWdyD67ktDMJGDp3jpm
June 01, 2003 - There is fair to good evidence that several
drug therapies have a beneficial effect on cognitive
function … the patients may have in understanding and
adhering to recommended therapy. … To assess possible benefits of detecting undiagnosed
dementia, the USPSTF examined trials of therapies … Donepezil
therapy in clinical practice: a randomized crossover
study. … Estrogen
replacement therapy for treatment of mild to
moderate Alzheimer disease: a randomized controlled
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/chlamydial-infection-including-ocular-prophylaxis-screening-1996
January 01, 1996 - In one study, one fourth of women with positive cultures did not return for therapy. 28 In men, screening … Early detection of chlamydial infections in asymptomatic persons permits initiation of antibiotic therapy … or doxycycline results in a short-term cure in 92-100% of women and 97-100% of men. 1 Single-dose therapy … failures are usually due to failure to treat sex partners, noncompliance with therapy, or reinfection … prevalence of asymptomatic infection, and the availability of reliable screening tests and effective treatments
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/oral-cancer-screening
November 15, 2013 - Treatment
Suspected oral cancer or its precursors detected on examination require confirmation by tissue … Treatment for screen-detected oral cancer includes surgery, radiotherapy, and chemotherapy. … cancer and treatment of screen-detected oral cancer improves morbidity or mortality. … Harms of Detection and Early Treatment
The USPSTF found inadequate evidence on the harms of screening … More evidence is needed to address effective screening strategies, treatment, and primary prevention.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/dementia-older-adults-screening-2003
June 03, 2003 - There is fair to good evidence that several drug therapies have a beneficial effect on cognitive function … clinicians to anticipate problems the patients may have in understanding and adhering to recommended therapy … To assess possible benefits of detecting undiagnosed dementia, the USPSTF examined trials of therapies … Donepezil therapy in clinical practice: a randomized crossover study. … Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled