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  1. effectivehealthcare.ahrq.gov/products/ptsd-adult-treatment-update/research-protocol
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
    November 01, 2014 - Effectiveness Reviews, the program supports systematic appraisals of existing scientific evidence regarding treatments … Appropriate antibiotic therapy significantly improves survival for patients with HAP.8-11 Relevant … The goal of these guidelines is to provide recommendations for the selection of adequate therapy and … would benefit from updated information that will point to more effective strategies for using current therapiesTherapeutic monitoring of vancomycin in adult patients: a consensus review of the American Society
  3. effectivehealthcare.ahrq.gov/sites/default/files/13_pulmonary_potential_high_impact_2012-12-11.pdf
    January 01, 2012 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address …  Key Facts: Current therapies for CF have improved median survival times, but patients with CF still … of Cystic Fibrosis in Patients with G551D-CFTR Mutation Current therapies for cystic fibrosis (CF … Available: http://www.cff.org/treatments/CFCareGuidelines/. 15. Expert Commenter 665.
  4. #05 DEPRESSION (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1306.pdf
    October 01, 2014 - Overall high-impact potential: deep brain stimulation (Reclaim DBS Therapy or Libra DBS) for treatment-resistant … and psychotherapy as first- and second-line therapies and electroconvulsive therapy or repetitive … They cited suboptimal current treatments, lack of an FDA-approved treatment for this condition, and … DBS therapy is incompatible with some other device- based depression treatments. … of Psychotic Depression Deep Brain Stimulation (Reclaim DBS Therapy or Libra DBS) for Treatment-Resistant
  5. effectivehealthcare.ahrq.gov/system/files/docs/acute-diverticulitis-topic-nomination.pdf
    August 13, 2018 - Furthermore, as new data on minimally-invasive treatments emerge, recommendations continue to evolve … A systematic review of high-fibre dietary therapy in diverticular disease. … Treatment of acute uncomplicated diverticulitis without antibiotics: risk factors for treatment failure … Intermittent versus every-day mesalazine therapy in preventing complications of diverticular disease … N=84 Key Question 4 Overall Search Results AND Treatments (KQ4) Laparoscopy/ or Therapeutic
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_executive.pdf
    June 01, 2012 - Moderate to Severe Traumatic Brain Injury in Adults Executive Summary Background Condition and Therapeutic … Often, progress in response to particular therapies is monitored with measures that evaluate isolated … They delivered therapies to small groups of individuals that progressed through rehabilitation together … of therapy session types, primarily in groups, and with a vocational component. … Cognitive Rehabilitation Therapy for Traumatic Brain Injury: Evaluating the Evidence.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-anxiety-children_0.pdf
    October 01, 2018 - medications.5-7 Choosing between the available treatments can be challenging at all levels of healthcare … They have also observed that evidence synthesis reports commonly review existing treatments and rarely … address recently approved treatments. … Furthermore, if these clinics have an established first line treatment such as group therapy; implementation … Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-203-adhd-disposition-comments.pdf
    January 01, 2018 - The discussion of the role of nonpharmacologic therapies, including behavior therapy, has been expanded … AAP recommends behavior therapy as the first line for preschoolers, and both stimulant therapy and … as the first line of therapy.11" Combination therapy is recommended for children 6 and older and behavior … broad range of studies that would allow inferences regarding competing therapies. … combination with medication therapy.
  9. effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1406.pdf
    February 01, 2015 - , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … predominantly symptom- management options; however, emerging research aims to identify disease-modifying therapies … AD pathogenesis, leading researchers to investigate intranasally delivered insulin as a potential therapy … Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central … Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot
  10. S38 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s38.pdf
    October 01, 2007 - If education or evidence leads providers to conclude that 1 therapeutic approach is preferred over others … Thus, measures of agreement in treatments received by patients of different providers within a practice … Improving drug-therapy decisions through educa- tional outreach: a randomized controlled trial of academically … Explained variation in a model of therapeutic decision making is partitioned across patient, physician … A review of use of health care utilization databases for epidemiologic research on therapeutics.
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-childhood-protocol.pdf
    August 06, 2018 - therapies.15-18 Existing treatments vary greatly in the number of trials testing efficacy, effectiveness … adaptation therapies Lifestyle Exercise (physical activity), diet therapy, mindfulness (including … adaptation therapies Lifestyle: Exercise (physical activity), diet therapy, mindfulness (including … Psychological Treatments That Cause Harm. … ” OR TX CBT OR TX “cognitive therapy” OR TX psychotherapy OR (cognitive AND (therap* OR treatment*
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_executive.pdf
    January 01, 2011 - test is usually determined by its indirect effect on outcomes, that is, through its influence on therapeutic … regimen (i.e., repletion or continuous treatment) • Interactions between treatments (i.e., patients … – Most of the reported harms were attributed to iron therapy. Key Question 3. … technical and clinical validity, to the assessment of test impact on clinicians’ diagnostic thinking and therapeutic … regimen (i.e., repletion or continuous treatment) – Interactions between treatments (i.e., patients
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
    September 01, 2010 - guidelines point to controversial areas in need of future research, including: treatments to achieve … versus initial combination therapy, we will collect data regarding prior therapy and will consider … analyzing those with and without prior therapy separately. … Treatments Aminosalicylates, Corticosteroids, Anti-metabolites, Biologics Maintain remission … OR azathioprine[tiab] OR methotrexate[tiab] OR “6-mercaptopurine”[tiab] OR “antibodies, monoclonal/therapeutic
  14. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_executive.pdf
    April 01, 2011 - Individual goals for treatment vary for different children and may include combinations of therapies.4 … individual providing the therapy? … treatment or across treatments? … outcomes assessment outside the therapeutic environment, with positive results observed. … The effect of therapeutic horseback riding on social functioning in children with autism.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-future_research.pdf
    October 26, 2012 - power Placebo comparators would contribute indirect evidence to help guide potential combination therapies … power Placebo comparators would contribute indirect evidence to help guide potential combination therapies … Patients’ attitudes toward novel therapies may inhibit enrollment; alternatively they may be open to … understanding the gut microbiome is a long-term type of endeavor which has the potential to lead to new therapeutics … , but in the interim, they are critical needs for immediate therapeutic options and prevention).
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_overview.pdf
    January 17, 2014 - In adults age 18 or older with type 2 diabetes mellitus, what is the comparative effectiveness of treatment … In adults age 18 or older with type 2 diabetes mellitus, what is the comparative effectiveness of treatment … Do safety and effectiveness of these treatment options (Table 2) differ across subgroups of adults with … Several recent studies have evaluated the use of combination therapies in adults with Type 2 Diabetes … Mellitus. . § In addition to updating information on the potential benefits of available treatments
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/disposition-of-comments-cer-192-anxiety-in-children.pdf
    August 31, 2017 - We have added a category for parent based treatments. … Per Key Question 2, harms were assessed for all treatments. … therapy consisted of. … psychotherapy” category due to the significant theoretical and methodological differences between these therapeutic … how I would have classified therapies.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-surveillance_research-protocol.pdf
    May 19, 2011 - A well-defined clinical benefit of immediate therapy with curative intent has not been demonstrated … Thus, all men who undergo treatment risk suffering the adverse events of the treatment, while only … at the earliest sign of worrisome progression; watchful waiting means postponing therapeutic interventions … Immediate treatments, either curative or palliative. Outcomes. … The impact of insurance and geographic factors on therapeutic decisionmaking will be examined with
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-update_clinician.pdf
    September 01, 2014 - Treatments for ASD focus on improving core deficits in social communication, addressing challenging … Individual goals for treatment vary by child, and a combination of therapies is used to achieve these … ., settings), components of multicomponent therapies that drive effectiveness, and predictors of treatment … � Re-evaluating potential treatments as research evolves. … � Available evidence on each program or therapy.
  20. effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
    October 30, 2012 - For example, the FACIT and EORTC families of measures for evaluating cancer therapies each include … function could be judged to have poor content validity, and might fail to capture differences among therapies … Severe psoriasis-- oral therapy with a new retinoid. Dermatologica. 1978;157(4):238-44. 5. U.S. … In: Assessment of Quality of Life in Clinical Trials of Cardiovascular Therapies. … Measuring quality of life in chronic illness: the functional assessment of chronic illness therapy

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