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effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
January 01, 2013 - Sensitivity analysis and external adjustment for unmeasured confounders in epidemiologic database studies of therapeutics … Sensitivity analysis and external adjustment for unmeasured confounders in epidemiologic database studies of therapeutics … Effect of highly active antiretroviral therapy on incident AIDS using calendar period as an instrumental … Hormone replacement therapy and cardiovascular health in the United States. … PMID:14585769.
http://www.ncbi.nlm.nih.gov/pubmed/14585769
Exposure time window
Period where therapeutic
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0713-140625.pdf
January 07, 2014 - nominator is interested in the comparative effectiveness of currently available and
Summary: emerging treatments … More specifically, the nominator is interested in the
effectiveness of pharmacological treatments including … Additionally, the nominator is interested in the adverse effects of pharmacotherapy
treatment options … symptoms
(LUTS) secondary to benign prostatic hyperplasia (BPH)
Intervention(s): Pharmacological treatments … , placebo, lifestyle changes, other pharmacological
treatments, and all other treatment options
Outcome
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement.pdf
February 05, 2025 - ,16 dialectical behavioral therapy,15
family therapy,17, 18 attachment-based therapies, and variations … a) What are the components of effective psychosocial treatments (e.g., frequency or
intensity of therapy … and/or aspects of the therapeutic modality)? … or
integrative health
interventions (e.g., light
therapy, supplements)
Comparators • Treatment … as usual
• Another psychosocial intervention
• Another pharmacological therapy
• Combination therapies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-executive-sum.pdf
January 01, 2024 - In
patients with chronic (mainly neuropathic) pain with short-term treatment (4 weeks to
<6 months) … strength of this evidence was
mostly low, more data are needed to confidently recommend cannabis as a treatment … https://effectivehealthcare.ahrq.gov/products
/plant-based-chronic-pain-
treatment/protocol. … Methodology for the development of
antithrombotic therapy and prevention of
thrombosis guidelines: … antithrombotic
therapy and prevention of thrombosis, 9th
ed: American College of Chest Physicians
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism_research-protocol.pdf
December 09, 2009 - gains once active therapy ends. … treatment or across treatments? … including music therapy and nutritional
therapies intended to modify the core symptoms of ASD
Comparators … interventions (e.g., autism, asperger, pervasive development, therapeutics, etc.). … This revision does not eliminate
specific medical therapies from the review as treatments are typically
-
effectivehealthcare.ahrq.gov/sites/default/files/therapies-for-autism-spectrum-disorder-2-9-2010.pdf
January 01, 2010 - gains once active therapy ends. … treatment or across treatments? … including music therapy and nutritional
therapies intended to modify the core symptoms of ASD
Comparators … interventions (e.g., autism, asperger, pervasive development, therapeutics, etc.). … This revision does not eliminate
specific medical therapies from the review as treatments are typically
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
January 01, 2012 - diabetes
and hypertension.16 In efforts to reduce the risk of
complications from these conditions, therapeutic … CKD Treatment Benefits and Harms
• In RCTs of patients with CKD stages 1–3, several
treatments reduced … with macroalbuminuria, ACEI or ARB treatment
in combination with other therapy, and treatments
other … • Patient-level meta-analyses of treatment RCTs to
evaluate the effect of treatments relative to … Effectiveness of statin
therapy in adults with coronary heart disease.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0359_10-15-2010.pdf
January 01, 2010 - Patients with multiple sclerosis or clinically isolated syndrome
Intervention(s): Disease-modifying therapies … for delay of relapse and disability,
treatments to address symptoms of multiple sclerosis, including … pharmaceutical and
non-pharmaceutical treatments
Comparator(s): Comparative effectiveness of disease-modifying … therapies, comparative
Diagnosis and Treatment of Multiple Sclerosis
Nomination Summary Document … There is no cure for MS; treatments aim to reduce the frequency and
hasten recovery from relapses and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_executive.pdf
May 01, 2010 - Treatments for Head
and Neck Cancer
Executive Summary
Effective Health Care Program
Effective Health … Therapy-related toxicities are
particularly relevant in the treatment of head and neck
cancer because … patients with head and neck cancer,
theoretical dose delivery advantages must be translated
into improved therapeutic … Older age and certain therapies for chronic
diseases may increase susceptibility for this adverse
effect … Comparative Effectiveness and Safety of Radiotherapy
Treatments for Head and Neck Cancer.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
January 01, 2023 - Executive Summary - Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic … Living Systematic Review on Cannabis and
Other Plant-Based Treatments for Chronic
Pain. … /products/plant-based-chronic-pain-treatment/protocol
https://effectivehealthcare.ahrq.gov/products/plant-based-chronic-pain-treatment … Methodology for the development of
antithrombotic therapy and prevention of
thrombosis guidelines: … antithrombotic
therapy and prevention of thrombosis, 9th
ed: American College of Chest Physicians
-
effectivehealthcare.ahrq.gov/products/urinary-incontinence-treatment/research
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2020.pdf
January 01, 2020 - Opioid Treatments for Chronic Pain. … Therapies for Clinically Localized Prostate Cancer. … Treatments for Acute Pain: A Systematic Review. … surveillance, surgery, brachytherapy, or
external beam radiation with or without androgen deprivation therapy … of a web-based tool to predict sexual, urinary, and bowel
function longitudinally after radiation therapy
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear-nomination-140925.pdf
March 20, 2014 - Selection Process & Next Steps
§ The topic, Comparative Effectiveness of Non-operative and Operative Treatments … PT treatment
Aquatic therapy with land-based therapy vs. land-based therapy
Inpatient vs. day patient … . o
treatment § Physical therapy vs. open or mini-open RCR
§ Physical therapy treatment, oral medication … What are the associated risks, adverse effects, and potential harms of
non-operative and operative therapies … Non-operative and Operative Treatments
for Rotator Cuff Tears: Future Research Needs.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dyspnea-protocol-amended.pdf
May 19, 2020 - Non-pharmacologic Treatment
Non-pharmacologic treatments potentially helpful for breathlessness include … .8, 9
Pharmacologic Treatment
Pharmacologic treatments for breathlessness in advanced cancer may … Cognitive-behavioral therapy (CBT)
b. … Exercise (healthcare professional-guided exercise, physical therapy,
occupational therapy, aerobic … Fan Therapy for the Treatment of
Dyspnea in Adults: a Systematic Review.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
April 01, 2013 - Food and Drug Administration (FDA)-approved antiviral therapies for antiviral-
naïve adults with chronic … Need for studies not funded by pharmaceutical companies, as almost all studies of
antiviral therapies … The CER focused on current
FDA-approved antiviral therapies for antiviral-naïve adults with chronic … Need for studies not funded by pharmaceutical companies, as almost all studies of
antiviral therapies … acid sequence of the HCV non-structural 3-4A protease
domain
NCT01474811 HCV-TARGET: Hepatitis C
Therapeutic
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
January 01, 2012 - Alternative Treatments
Comparison of a treatment with a clinically
meaningful alternative treatment … analysis and external
adjustment for unmeasured confounders in
epidemiologic database studies of therapeutics … Effect
of highly active antiretroviral therapy on
incident AIDS using calendar period as an
instrumental … Hormone
replacement therapy and cardiovascular health in
the United States. Med Care. … Cancer risk in patients with rheumatoid
arthritis treated with anti–tumor necrosis factor
a therapies
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
September 20, 2017 - Although many of the same treatments may be employed for each of these
conditions, treatment effectiveness … Pharmacological Treatment
Pharmacological treatments for chronic pain include nonsteroidal anti-inflammatory … (Yoga, Tai Chi, Qigong), psychological therapies
(cognitive-behavioral therapy, biofeedback, relaxation … /
14 exp Physical Therapy Modalities/
15 exp Braces/
16 exp Mind-Body Therapies/
17 exp Acupuncture … /
14 exp Physical Therapy Modalities/
15 exp Braces/
16 exp Mind-Body Therapies/
17 exp Acupuncture
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-adults-prisons_executive.pdf
August 01, 2013 - Four trials tested the efficacy of pharmacologic therapies. … Investigators compared cognitive therapy with other
psychological treatment in three trials. … Evidence was
insufficient that any of the other treatments assessed (other
pharmacologic therapies, … cognitive therapy
to be more effective than other standard psychological
treatment. … Direct Insufficient
Modified therapeutic
community vs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_disposition-comments.pdf
September 01, 2011 - Therefore it is good that this report includes trials
comparing to controls, sham therapies and pharmacological … The study
compares baseline and post-treatment
outcomes after electroconvulsive therapy. … Their call for action, such as
more uniformity in diagnosis and in therapeutic protocols, is well
thought … patient receiving
long-term dynamic therapy was better off than 96% of patients
receiving other treatments … Cognitive
therapy versus medication in augmentation and switch strategies as
second-step treatments
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
May 24, 2010 - Increasing morbidity and mortality of C. difficile infection, the limited therapeutic options
and difficulty … Care Resident
Yes
No
Technical
Efficacy
Diagnostic
Accuracy
Diagnostic Thinking and
Therapeutic … Studies for standard treatments which include non-U.S. approved treatments will be retained if
the treatment … Emerging therapies in the treatment of Clostridium
difficile-associated disease. … Probiotic therapy for the prevention and treatment of
Clostridium difficile-associated diarrhea: a systematic