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  1. effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
    January 01, 2013 - Sensitivity analysis and external adjustment for unmeasured confounders in epidemiologic database studies of therapeutics … Sensitivity analysis and external adjustment for unmeasured confounders in epidemiologic database studies of therapeutics … Effect of highly active antiretroviral therapy on incident AIDS using calendar period as an instrumental … Hormone replacement therapy and cardiovascular health in the United States. … PMID:14585769. http://www.ncbi.nlm.nih.gov/pubmed/14585769 Exposure time window Period where therapeutic
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0713-140625.pdf
    January 07, 2014 - nominator is interested in the comparative effectiveness of currently available and Summary: emerging treatments … More specifically, the nominator is interested in the effectiveness of pharmacological treatments including … Additionally, the nominator is interested in the adverse effects of pharmacotherapy treatment options … symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) Intervention(s): Pharmacological treatments … , placebo, lifestyle changes, other pharmacological treatments, and all other treatment options Outcome
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement.pdf
    February 05, 2025 - ,16 dialectical behavioral therapy,15 family therapy,17, 18 attachment-based therapies, and variations … a) What are the components of effective psychosocial treatments (e.g., frequency or intensity of therapy … and/or aspects of the therapeutic modality)? … or integrative health interventions (e.g., light therapy, supplements) Comparators • Treatment … as usual • Another psychosocial intervention • Another pharmacological therapy • Combination therapies
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-executive-sum.pdf
    January 01, 2024 - In patients with chronic (mainly neuropathic) pain with short-term treatment (4 weeks to <6 months) … strength of this evidence was mostly low, more data are needed to confidently recommend cannabis as a treatment … https://effectivehealthcare.ahrq.gov/products /plant-based-chronic-pain- treatment/protocol. … Methodology for the development of antithrombotic therapy and prevention of thrombosis guidelines: … antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism_research-protocol.pdf
    December 09, 2009 - gains once active therapy ends. … treatment or across treatments? … including music therapy and nutritional therapies intended to modify the core symptoms of ASD Comparators … interventions (e.g., autism, asperger, pervasive development, therapeutics, etc.). … This revision does not eliminate specific medical therapies from the review as treatments are typically
  6. effectivehealthcare.ahrq.gov/sites/default/files/therapies-for-autism-spectrum-disorder-2-9-2010.pdf
    January 01, 2010 - gains once active therapy ends. … treatment or across treatments? … including music therapy and nutritional therapies intended to modify the core symptoms of ASD Comparators … interventions (e.g., autism, asperger, pervasive development, therapeutics, etc.). … This revision does not eliminate specific medical therapies from the review as treatments are typically
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
    January 01, 2012 - diabetes and hypertension.16 In efforts to reduce the risk of complications from these conditions, therapeutic … CKD Treatment Benefits and Harms • In RCTs of patients with CKD stages 1–3, several treatments reduced … with macroalbuminuria, ACEI or ARB treatment in combination with other therapy, and treatments other … • Patient-level meta-analyses of treatment RCTs to evaluate the effect of treatments relative to … Effectiveness of statin therapy in adults with coronary heart disease.
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0359_10-15-2010.pdf
    January 01, 2010 - Patients with multiple sclerosis or clinically isolated syndrome Intervention(s): Disease-modifying therapies … for delay of relapse and disability, treatments to address symptoms of multiple sclerosis, including … pharmaceutical and non-pharmaceutical treatments Comparator(s): Comparative effectiveness of disease-modifying … therapies, comparative Diagnosis and Treatment of Multiple Sclerosis Nomination Summary Document … There is no cure for MS; treatments aim to reduce the frequency and hasten recovery from relapses and
  9. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_executive.pdf
    May 01, 2010 - Treatments for Head and Neck Cancer Executive Summary Effective Health Care Program Effective Health … Therapy-related toxicities are particularly relevant in the treatment of head and neck cancer because … patients with head and neck cancer, theoretical dose delivery advantages must be translated into improved therapeutic … Older age and certain therapies for chronic diseases may increase susceptibility for this adverse effect … Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
    January 01, 2023 - Executive Summary - Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic … Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain. … /products/plant-based-chronic-pain-treatment/protocol https://effectivehealthcare.ahrq.gov/products/plant-based-chronic-pain-treatment … Methodology for the development of antithrombotic therapy and prevention of thrombosis guidelines: … antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians
  11. effectivehealthcare.ahrq.gov/products/urinary-incontinence-treatment/research
  12. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2020.pdf
    January 01, 2020 - Opioid Treatments for Chronic Pain. … Therapies for Clinically Localized Prostate Cancer. … Treatments for Acute Pain: A Systematic Review. … surveillance, surgery, brachytherapy, or external beam radiation with or without androgen deprivation therapy … of a web-based tool to predict sexual, urinary, and bowel function longitudinally after radiation therapy
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear-nomination-140925.pdf
    March 20, 2014 - Selection Process & Next Steps § The topic, Comparative Effectiveness of Non-operative and Operative Treatments … PT treatment Aquatic therapy with land-based therapy vs. land-based therapy Inpatient vs. day patient … . o treatment § Physical therapy vs. open or mini-open RCR § Physical therapy treatment, oral medication … What are the associated risks, adverse effects, and potential harms of non-operative and operative therapies … Non-operative and Operative Treatments for Rotator Cuff Tears: Future Research Needs.
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/dyspnea-protocol-amended.pdf
    May 19, 2020 - Non-pharmacologic Treatment Non-pharmacologic treatments potentially helpful for breathlessness include … .8, 9 Pharmacologic Treatment Pharmacologic treatments for breathlessness in advanced cancer may … Cognitive-behavioral therapy (CBT) b. … Exercise (healthcare professional-guided exercise, physical therapy, occupational therapy, aerobic … Fan Therapy for the Treatment of Dyspnea in Adults: a Systematic Review.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
    April 01, 2013 - Food and Drug Administration (FDA)-approved antiviral therapies for antiviral- naïve adults with chronic … Need for studies not funded by pharmaceutical companies, as almost all studies of antiviral therapies … The CER focused on current FDA-approved antiviral therapies for antiviral-naïve adults with chronic … Need for studies not funded by pharmaceutical companies, as almost all studies of antiviral therapies … acid sequence of the HCV non-structural 3-4A protease domain NCT01474811 HCV-TARGET: Hepatitis C Therapeutic
  16. effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
    January 01, 2012 - Alternative Treatments Comparison of a treatment with a clinically meaningful alternative treatment … analysis and external adjustment for unmeasured confounders in epidemiologic database studies of therapeutics … Effect of highly active antiretroviral therapy on incident AIDS using calendar period as an instrumental … Hormone replacement therapy and cardiovascular health in the United States. Med Care. … Cancer risk in patients with rheumatoid arthritis treated with anti–tumor necrosis factor a therapies
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
    September 20, 2017 - Although many of the same treatments may be employed for each of these conditions, treatment effectiveness … Pharmacological Treatment Pharmacological treatments for chronic pain include nonsteroidal anti-inflammatory … (Yoga, Tai Chi, Qigong), psychological therapies (cognitive-behavioral therapy, biofeedback, relaxation … / 14 exp Physical Therapy Modalities/ 15 exp Braces/ 16 exp Mind-Body Therapies/ 17 exp Acupuncture … / 14 exp Physical Therapy Modalities/ 15 exp Braces/ 16 exp Mind-Body Therapies/ 17 exp Acupuncture
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-adults-prisons_executive.pdf
    August 01, 2013 - Four trials tested the efficacy of pharmacologic therapies. … Investigators compared cognitive therapy with other psychological treatment in three trials. … Evidence was insufficient that any of the other treatments assessed (other pharmacologic therapies, … cognitive therapy to be more effective than other standard psychological treatment. … Direct Insufficient Modified therapeutic community vs.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_disposition-comments.pdf
    September 01, 2011 - Therefore it is good that this report includes trials comparing to controls, sham therapies and pharmacological … The study compares baseline and post-treatment outcomes after electroconvulsive therapy. … Their call for action, such as more uniformity in diagnosis and in therapeutic protocols, is well thought … patient receiving long-term dynamic therapy was better off than 96% of patients receiving other treatments … Cognitive therapy versus medication in augmentation and switch strategies as second-step treatments
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
    May 24, 2010 - Increasing morbidity and mortality of C. difficile infection, the limited therapeutic options and difficulty … Care Resident Yes No Technical Efficacy Diagnostic Accuracy Diagnostic Thinking and Therapeutic … Studies for standard treatments which include non-U.S. approved treatments will be retained if the treatment … Emerging therapies in the treatment of Clostridium difficile-associated disease. … Probiotic therapy for the prevention and treatment of Clostridium difficile-associated diarrhea: a systematic

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