-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_overview.pdf
January 17, 2014 - In adults age 18 or older with type 2 diabetes mellitus, what is the
comparative effectiveness of treatment … In adults age 18 or older with type 2 diabetes mellitus, what is the
comparative effectiveness of treatment … Do safety and effectiveness of these treatment options (Table 2) differ
across subgroups of adults with … Several recent studies have evaluated the use of
combination therapies in adults with Type 2 Diabetes … Mellitus. .
§ In addition to updating information on the potential benefits of available treatments
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
February 01, 2018 - similar across
interventions used to treat a given condition (e.g., medications, non-pharmacological therapies … Title
EPC, Year
Condition/ Population Harms Related Key Question(s) Interventions Harms Outcomes
Therapies … Dual agent therapy (statin
+ lipid modifying
medication) and
intensification of statin
therapy … Graded Exercise
Treatment;
pharmaceutical;
counseling/behavioral
therapy; complimentary
alternative … Therapeutic:
suppression of adrenal
glucocorticoid responsiveness;
increased appetite; weight gain
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0278_03-10-2008.pdf
January 01, 2008 - includes hand washing, in-hospital infection
control, appropriate antibiotic prescribing, and effective treatment … Date: 6-2-09
2
The literature on this topic indicates that large studies with more standardized treatment … regimens are
needed to evaluate the effectiveness of treatments for CDAD.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND__0355_09-22-2010.pdf
January 01, 2010 - benzodiazepine receptor agonists, or antidepressants), complementary and alternative
care, relaxation therapy … , cognitive behavioral therapy, hormones
Comparator(s): Placebo or comparison to another insomnia … Treatment of chronic insomnia is a dilemma commonly encountered in primary care. … medications are most effective and when medications should be used as
opposed to nonpharmacologic treatments
-
effectivehealthcare.ahrq.gov/sites/default/files/hunt_panel_1.pdf
January 01, 2010 - Slide
3: Knowledge-‐Practice Gap
• Evidence-‐based treatments can
double or even
triple … (Twitter)
• Reach different people
o Support networks
o Diabetes patients who do not adhere to treatment
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
May 14, 2010 - Evidence-based Practice Center Systematic Review Protocol
Project Title: Comparative Effectiveness of Treatments … pamidronate, and zoledronic acid
• Calcium
• Denosumab (awaiting FDA approval)
• Menopausal hormone therapy … of pharmacotherapy,
and what are the comparative anti-fracture efficacies of continued long-term
therapy … follow-up period) (c)
KQ4: What are the short- and long-term harms (adverse effects) of the above therapies … monitored (via measurement of bone mineral
density) during therapy?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
December 01, 2012 - group (i.e., comparison
of different treatments, hormonal vs. surgical therapy,
or treatment vs. no … Effectiveness of Hormone Therapy
Fourteen studies in 19 publications assessed hormonal
therapy in treatment … Effectiveness of Surgical Treatments
Twenty-six studies addressed surgical treatment. … This
report reviews the literature on treatment planning and
therapeutic interventions to achieve these … Strength of evidence of surgical treatments for cryptorchidism
Outcome Treatment
Number of Studies;
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea_research-protocol.pdf
March 15, 2010 - Treatment
Continuous positive airway pressure (CPAP) is the standard 1st-line therapy for most
patients … Treatment
KQ5: What is the comparative effect of different treatments for obstructive sleep apnea (OSA … KQ6: In OSA patients prescribed non-surgical treatments, what are the associations of pre-
treatment … Treatment, therapy,
or intervention
(No KQ) (KQ 5)
(KQ 5)
(KQ 5)
Health … Source: www.effectivehealthcare.ahrq.gov
Published Online: March 15, 2010
17
40 exp Therapeutics
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
June 01, 2013 - new (and new uses of existing) pharmaceuticals, medical devices,
diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care
delivery innovations that address … Key Facts: Before the approval of ivacaftor, therapies for CF had improved median survival
times … Better
treatments to prevent COPD exacerbations are needed. … Although the cost of azithromycin therapy would be
additive to current treatment costs, its low cost
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/choice-of-mean_white-paper.pdf
April 01, 2015 - Assistant Professor, Department of Physical Therapy
Florida International University
Miami, FL
Steven … comparison of combined mean differences using change score and
endpoints (comparison between different treatments … , diabetes, and
alcohol abuse, and the interventions included pharmacologic, behavioral, and other therapies … Diagnosis and Treatment of Obstructive
Sleep Apnea in Adults. … Nonpharmacologic Interventions for
Treatment-Resistant Depression in Adults.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_clinician.pdf
January 01, 2017 - Treatments for gout attacks include nonsteroidal anti-
inflammatory drugs (NSAIDs), colchicine, and … Management of Gout:
�� Effective treatments for gout attacks include NSAIDs,
colchicine, and corticosteroids … Table 2: Effectiveness of Treatments for Acute Gout Attack: Key Findings
Strategy N Studies N Subjects … Diet, lifestyle, and complementary and alternative medicine
therapies for managing gout
��There has … Effectiveness of therapy for gout in subpopulations
��The efficacy of pharmacological therapies for gout
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
April 17, 2012 - new (and new uses of existing) pharmaceuticals, medical devices,
diagnostic tests and procedures, therapeutic … All experts generally indicated that these antiobesity therapies have high potential to meet a
significant … the company in March 2011.
57
As of July 25, 2011, the system had
been approved by the Australian Therapeutic … Goods Administration for inclusion in its therapeutic
goods registry for treatment of T2DM and obesity … Orexigen Therapeutics provides a regulatory
update on Contrave NDA. [internet].
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
June 01, 2015 - , screening and diagnostics, therapeutics, surgery, programs, and
care delivery innovations that address … Effective treatments are needed. … Patients with AS who did not respond to prior treatment with
TNF therapies showed significant improvement … Secukinumab (Cosentyx) for Treatment of Psoriatic Arthritis
Key Facts: Current treatments for PsA … Clinical Pathway at Point of This Intervention
AS treatment focuses on physical therapy and exercise
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0064_11-23-2008.pdf
January 01, 2008 - Document Completion Date: 6-25-09
1
Results of Topic Selection Process & Next Steps
Treatment … Nomination
Summary:
The anonymous nominator is interested in the comparative risks and benefits of
treatments … Does treatment response vary for African-Americans as compared to those who are
not African-Americans … Treatment of Open-Angle Glaucoma
Nomination Summary Document
http://effectivehealthcare.ahrq.gov/index.cfm … There
are no recent guidelines on the treatment of glaucoma in the US.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-medical-update_research-protocol.pdf
February 16, 2016 - b) Is the effectiveness of the therapies reviewed affected by co-interventions or prior
treatment … targeting sensory challenges as driving outcomes, either
within a single treatment or across treatments … [sh] OR therapeutics[mh] OR teaching[mh] OR psychotherapy[mh] OR
treatment outcome[mh]
7275093 …
5 (treatment[tiab] OR therapy[tiab] OR intervention[tiab] OR “control group”[tiab]
OR … "[Mesh]) OR ( "drug therapy" [Subheading] OR "Medication
Therapy Management"[Mesh] )
2368930
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0119_06-17-2009.pdf
January 01, 2009 - Completion Date: 1-12-10
1
Results of Topic Selection Process & Next Steps
Pharmacologic therapy … versus medical foods and nondietary approaches for the treatment of
phenylketonuria (PKU) will go forward … They are also interested in the
comparative cost effectiveness of these treatments. … Pharmacologic Therapy versus Medical Foods
for the Treatment of Phenylketonuria (PKU)
Nomination … Historically, the treatment of PKU has relied on nonpharmacologic therapies, with affected individuals
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/presentations-future_research.pdf
April 01, 2012 - Angiotensin Converting Enzyme Inhibitors or Angiotensin
II Receptor Blockers Added to Standard Medical Therapy … 20
Inhaled Nitric Oxide Therapy for Premature Infants. … treatment to an
existing treatment
after treatment
failure
Initial treatment with
psychosocial … and/or
pharmacologic
treatments
or
Continuation of
existing treatment
without addition of
psychosocial … and/or
pharmacologic
treatment or switch to
different treatment
Outcomes for
children and
parents
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0161_09-01-2009.pdf
January 01, 2009 - All individuals with asthma over the age of 5
Intervention(s): Buteyko breathing
Comparator(s): Treatment … how-are-research-topics-chosen/
Topic Number(s): 0205
Document Completion Date: 2-5-10
2
Medical treatment … There is no known cure for asthma;
therefore, all treatments are directed toward symptom reduction. … of interest to clinicians, patients, and
parents of children with asthma as an adjunct to standard therapies … Although uncommon in the US, it is sometimes used as a treatment
strategy outside of the US.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemorrhage-postpartum_executive.pdf
April 01, 2015 - PPH management
may also involve adjunctive therapies, such as blood and
fluid replacement and/or an … of care, the availability of
medications or other therapeutic options, the availability
of personnel … Treatment availability and the feasibility of
providing certain treatments differ across developed and … This lack of direct comparison of treatment options
hinders our ability to understand what treatments … The most effective treatments and the
order in which to use treatments remain unclear.
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1512.pdf
December 29, 2015 - , screening and diagnostics, therapeutics, surgery, programs, and
care delivery innovations that address … Treatments such as nonsteroidal anti-inflammatory
drugs (NSAIDs) are used for first-line therapy to … Patients with AS who did not respond to prior treatment with TNF
therapies showed significant improvement … with
existing therapies. … Clinical Pathway at Point of This Intervention
AS treatment focuses on physical therapy and exercise