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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary11/carotid-artery-stenosis-screening-december-2007
December 15, 2007 - search for RCTs, systematic reviews, and meta-analyses that compared carotid endarterectomy with medical therapy … angiographically confirmed CAS 60% or greater for random allocation to carotid endarterectomy or medical therapy … any perioperative stroke or death was lower in the carotid endarterectomy group than in the medical therapy … It is difficult to determine what effect current standard medical therapy would have on overall benefit … The use of current medical therapy could have reduced the stroke rate in the medical treatment arm of
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/N3VeYbr4ZdhZfqsw3ErLHE
November 01, 2014 - Studies comparing CEA or CAAS with current
standard medical therapy are needed. … therapy alone and followed the patients for 2.7 to
9 years. … beyond current standard medical therapy. … and benefit beyond
standard preventive treatments based on traditional cardio-
vascular risk factors … of medical
and surgical treatments, including the potential incremen-
tal benefit of CEA.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6cRgd5whkAvSGESSQsrQLR
January 01, 2020 - Treatments and
Interventions
Asymptomatic adults at increased risk for CVD are usually treated with … Two RCTs (total N = 4626) compared using the ABI to guide
decisions to start aspirin therapy vs usual … the effect of screening with
CAC score on risk perception, adherence to medication, and behav-
ioral therapies … Some comments also expressed
belief that CAC score testing leads to better adherence to preven-
tive therapies … It recommends judicious use of secondary test-
ing among patients for whom the need for statin therapy
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/9Tse2TwVFQgYb-aNCq4Ngv
September 04, 2018 - For
evidence on the harms of treatment (KQ3), studies of penicillin
treatment for syphilis in pregnant … the timing of screening, treatment, or both (eg, if screening,
treatment, or both occurred earlier in … Harms of Treatment
Key Question 3. … review was primarily focused on
screening, it did not address the efficacy of alternative antibiotic
treatments … Sexually transmitted
diseases treatment guidelines, 2015.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/carotid-artery-stenosis-screening
November 14, 2019 - Does surgical repair provide incremental benefit beyond current medical treatment for asymptomatic persons … intima-media thickness for CVD risk prediction
Comparisons
KQs 1, 2: No screening
KQ 3: Medical treatment … /usual care (e.g., statins, antiplatelet medications)
KQ 4: Medical treatment/usual care or noncomparative
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/cognitive-impairment-in-older-adults-screening-2014
March 18, 2014 - Treatment
Pharmacologic treatments approved by the U.S. … Evidence shows that several drug therapies and nonpharmacologic interventions have a small effect on … allows clinicians to anticipate problems patients may have in understanding and adhering to recommended therapy … Pharmacologic treatments approved by the U.S. … Treatment of mild to moderate dementia with several drug therapies and nonpharmacologic interventions
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/breast-cancer-medication-use-reduce-risk
March 21, 2024 - Exclude
Aim
The use of medications to prevent primary breast cancer
Use of medications for treatment … or prevention of other outcomes (e.g., breast cancer reoccurrence, treatment of osteoporosis) … prevention of primary breast cancer or unavailable in the United States
Comparisons
Placebo, no treatment
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-pregnant-women/human-immunodeficiency-virus-hiv-infection-screening
June 15, 2017 - . † Harms of treatment include adverse maternal and infant outcomes associated with use of antiretroviral … therapy. … treatment interruption
Comparisons
KQs 1, 3: HIV screening vs. no screening
KQ 2: Repeat … the USPSTF revised the analytic framework to differentiate the harms of screening from the harms of treatment … diagnostic staging step, and clarify that the evidence review will focus on the benefits and harms of treatment
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ZR66ep5ABbQCUQy7KTDETn
July 01, 2014 - HBV treatment consists of antiviral regimens. … Approved first-line treatments are pegylated interferon- 2a, entecavir, and
tenofovir. … Treatment
Antiviral Regimens
The goals of antiviral treatment are to achieve sus-
tained suppression … Approved
first-line treatments are pegylated interferon-�2a, enteca-
vir, and tenofovir. … Combination therapies have been eval-
uated but are not approved by the U.S.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/HUjbcP7uLa2SrGpVW4Fbhd
for localized prostate cancer include watchful waiting, active surveillance, surgery, and radiation therapy … There is no consensus regarding optimal treatment. … discomfort of prostate biopsy and the psychological harm of false-positive test results.
• Harms of treatment … years or older and for those whose life
expectancy is 10 years or fewer, the incremental benefit from
treatment
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/DcUgaNRhU6PvJWXqqsa8X7
Treatment and
Interventions
Treatment of early-stage colorectal cancer generally consists of local … Screening is most
appropriate for those healthy enough to undergo treatment and
those without comorbid
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/impaired-visual-acuity-in-older-adults-screening-2016
March 01, 2016 - for wet AMD (laser photocoagulation and photodynamic therapy). … Conclusions from the 2009 USPSTF review regarding the
effectiveness of treatments vs no treatment … language
studies has little effect on conclusions of reviews of noncomplementary
and alternative therapies … . 62 In addition, trials of therapy
for dry AMD evaluated heterogeneous vitamins, antioxidants, … Research is also needed to understand
the effectiveness of new therapies that are being investigated
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/36geybKjEXsHDoPkRR5KVZ
June 01, 2008 - of dyslipidemia, and as-
pirin therapy. … Several secondary pre-
vention trials of treatments for people with lipid abnormal-
ities reported that … reduce development and
progression of albuminuria, it could not determine
whether initiating these treatments … Treatments for diabetes are relatively safe. … Aspirin therapy in diabetes. Diabetes Care. 1997;20:1767-71.
[PMID: 9353620]
29.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-nonpregnant-adolescents-and-adults/human-immunodeficiency-virus-hiv-infection-screening
June 15, 2017 - . † Harms of treatment include adverse effects associated with antiretroviral therapy, including cardiometabolic … studies
KQ 5: Randomized, controlled trials and controlled observational studies; will consider treatment … diagnostic staging step, and clarify that the evidence review will focus on the benefits and harms of treatment … with antiretroviral therapy. … therapy regimens."
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/KbJjfcaP9XvhkP43u-7b9q
July 01, 2014 - Food and Drug
Administration versus placebo or no treatment or first-
line antiviral therapies (entecavir … Antiviral therapy versus placebo or no treatment for HBeAg loss. … Antiviral therapy versus placebo or no treatment for HBV DNA loss. … Antiviral therapy versus placebo or no treatment for HBsAg loss. … Antiviral therapy versus placebo or no treatment for incident cirrhosis.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/kQWchAnAnGxbQmpV9Gwo2H
Treatment and
Interventions
Treatments for ASD include behavioral, medical, educational, speech/language … , and occupational therapy and complementary and
alternative medicine approaches. … Treatments for young children are primarily behavioral interventions, particularly early intensive
behavioral
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/vision-in-children-ages-6-months-to-5-years-screening
December 17, 2015 - For children with amblyopia, its risk factors, or refractive error, treatment may improve health outcomes … Treatment may also result in harms (key question 5). … Does treatment of amblyopia, its risk factors, and refractive error in children ages 6 months to 5 years … What are the harms of treatment of amblyopia, its risk factors, and refractive error in children ages … refractive error (eyeglasses); penalization of the nonamblyogenic eye (eye patch, atropine); and vision therapy
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/7eLc5kBtomL_HKpYDwsFPf
July 01, 2009 - For ben-
efits and harms of treatments, quantitative estimates for treatment
effects from good-quality … For efficacy of treatments, we reported
quantitative estimates for treatment effects from previously … Treatment of age-related macular degeneration with
photodynamic therapy (TAP) Study Group. … Treatment of Age-Related Macular Degeneration with Photodynamic
Therapy (TAP) Study Group. … Treatment of Age-Related Macular Degeneration with Photodynamic
Therapy Study Group.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review86/rh-d-incompatibility-screening
February 15, 2004 - fetal anemia in pregnancies complicated by Rh (D) incompatibility. 2 , 3
Key Question 3: Have new treatment … We found no RCTs with direct evidence addressing new treatment protocols developed and tested to show … Key Questions 4 and 5: Have new harms been identified for screening or treatment
of Rh (D) incompatibility … no RCTs with direct evidence identifying either new or stronger harms associated with screening or treatment
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary1/osteoporosis-screening-june-2018
June 26, 2018 - Pharmacologic treatments for osteoporosis inhibit osteoclastic bone resorption (antiresorptive agents … Eligible treatments included US Food and Drug Administration (FDA)–approved pharmacotherapy (specifically … Benefits of Treatment
Key Question 4a. … Bone modeling and remodeling: potential as therapeutic targets for the treatment of osteoporosis. … Fracture risk and zoledronic acid therapy in men with osteoporosis.