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  1. effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … When these therapies fail to achieve relief, surgical treatments may be proposed, such as arthroplasty … Current treatments for OA include over-the-counter pain medication, exercise and/or physical therapy … Autologous MSCs have also been given with other therapies, including platelet-rich plasma (PRP) therapy
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear-nomination-140925.pdf
    March 20, 2014 - Selection Process & Next Steps § The topic, Comparative Effectiveness of Non-operative and Operative Treatments … PT treatment Aquatic therapy with land-based therapy vs. land-based therapy Inpatient vs. day patient … . o treatment § Physical therapy vs. open or mini-open RCR § Physical therapy treatment, oral medication … What are the associated risks, adverse effects, and potential harms of non-operative and operative therapies … Non-operative and Operative Treatments for Rotator Cuff Tears: Future Research Needs.
  3. CERs Report cover (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-feature-treatment-future_research.pdf
    September 23, 2010 - Background The 2009 systematic literature review “Treatments of Common Hip Fractures” was conducted … Of the top seven ranked research questions, only three, treatments for frail elderly patients and the … Of the top seven ranked research questions, only three, treatments for frail elderly patients and the … The third area, the optimal treatments for frail elderly hip fracture patients, reflects the changing … researchers with broad hip fracture outcomes and rehabilitation interests were added, including physical therapy
  4. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-2005_executive.pdf
    January 01, 2005 - For these patients, who have chronic GERD, most authorities consider the goals of therapy to be improvement … the short- and long-term adverse effects associated with specific medical, surgical, and endoscopic therapies … Conclusions Comparison of medical treatments with surgery Medical therapy with PPIs and surgery (fundoplication … medical treatments with endoscopic treatments. … laparoscopic fundoplication were satisfied with their results compared with those who had endoscopic therapies
  5. effectivehealthcare.ahrq.gov/sites/default/files/fecal-incontinence_disposition-comments.pdf
    March 21, 2016 - We edited the statement to read: Treatments for FI are imperfect and treatment combinations are common … Treatments for FI are imperfect and treatment combinations are common. … Combination therapy with biofeedback, loperamide, and stool-bulking agents is effective for the treatment … Stepped therapy is the norm as expressed in the Intro. … engaging patients in a conversation about risks and benefits of each therapeutic option is important
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research-protocol.pdf
    November 19, 2012 - Testing and Treatment Treatment for CUR is dependent on etiology. … , and pharmacologic treatments. … Table 1 lists the various surgical and nonsurgical treatments for CUR. … silodosin); 5-Alpha Reductase Inhibitors (5-ARI): dutasteride, finasteride; AB + 5- ARI combination therapy … duration Setting Any treatment setting.
  7. effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … Pharmacologic therapies can address symptoms of hyperactivity and depression, but effective pharmacologic … Cypress Bioscience acquires novel intranasal carbetocin therapy for autism; therapy may represent … Autism treatments and drugs. [internet].
  8. effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1512.pdf
    November 01, 2016 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … or payers may require a step- therapy approach starting with existing endometriosis treatments before … or payers 3 may require step therapy in which patients try existing endometriosis treatments before … They noted its anticipated higher cost than alternative therapies available as generics may increase
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
    April 01, 2013 - Individual RCTs did not provide sufficient evidence to conclude whether combined therapy was more effective … Patients with prior stable topiramate use experienced worsening in quality of life with combined therapy … support.40 For instance, the Institute for Healthcare 19 Informatics Health National Disease and Therapeutic … Impact of migraine and migraine therapy on productivity and quality of life. … Migraine prevalence, disease burden, and the need for preventive therapy.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
    November 22, 2011 - standard clopidogrel dosing, increased clopidogrel dosing, and non–clopidogrel-based antiplatelet therapies … testing for CYP2C19 variants Test-guided antiplatelet therapy Treatment with antiplatelet … therapy Phenotypic testing for platelet response Test-guided change of treatment KQ3a … Treatment with antiplatelet therapy Adverse effects of test-directed treatment KQ 1c, 2c, … the therapeutic strategy (if the treatment response is deemed to be inadequate).
  11. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1412.pdf
    January 01, 2015 - therapeutic effects and better glycemic control. … The mode of delivery, an implanted pump, is an established therapy for other drugs or other treatments … Unlike other treatments for T2DM, management of therapy with the ITCA 650 is controlled by the device … , corticosteroids, or anti-VEGF therapies, making this new intervention just another treatment option … Investigational therapeutic options in the management of DME: investigational pharmacologic treatments
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_disposition-comments.pdf
    July 26, 2012 - A search for molecular markers that will help tailor therapy is needed. … We agree that future research should investigate novel therapies to prevent recurrence of calcium oxalate … use of unnecessary and/or ineffective therapies in asymptomatic patients that may result in treatment … Previous systematic reviews of randomized controlled trials (RCTs) of dietary and pharmacological therapies … medical strategies was to determine the efficacy and adverse effects of dietary and pharmacologic therapies
  13. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
    December 01, 2011 - These second-generation treatments include selective serotonin reuptake inhibitors (SSRIs: citalopram … Effectiveness Reviews, the program supports systematic appraisals of existing scientific evidence regarding treatments … One trial showed that supplementing fluoxetine therapy with eszopiclone leads to improved sleep. … This treatment effect was consistent across all studies. … at treatment initiation would improve response rates.
  14. effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-13121.pdf
    December 05, 2013 - When these therapies fail to achieve relief, surgical treatments may be proposed, such as arthroplasty … Current treatments for OA include over-the-counter pain medication, exercise and/or physical therapy … Autologous MSCs have also been given with other therapies, including platelet-rich plasma (PRP) therapy … of treatments required. … The cost of one PRP treatment was purported to be lower than the cost of three hyaluronic acid treatments
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0368_11-08-2010.pdf
    January 01, 2010 - , sham, or standard treatment. … from specific physical diseases Interventions: Mindfulness-based stress programs Comparators: No treatment … , sham, or standard treatment Outcomes: Patient-reported outcomes, such as stress and well-being, and … clinical biomarker outcomes, such as cortisol Timing: Duration of therapy, duration of improvements … Setting: Group and individual treatment settings Key Questions from Nominator: None
  16. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/14_substanceabuse_potential_high_impact_june_2012.pdf
    January 01, 2012 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … For this report, topics that emerged as higher impact focused on treatments for opioid and nicotine … — as do current therapies—but that the monthly visit to a provider for the injection represents a small … About buprenorphine therapy. [internet].
  17. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … Because of even greater morbidity risk, therapeutic intervention is considered to be urgently needed … In September 2014, FDA approved naltrexone-bupropion (Contrave®, Orexigen Therapeutics, Inc., La Jolla … A pathway to endoscopic bariatric therapies. Gastrointest Endosc. 2011 Nov;74(5):943-53.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/suda-final-protocol.pdf
    October 02, 2018 - For behavioral treatments, AACAP concluded that family therapy models “have the most supporting evidence … bullets, in bold)  Family Therapies o Family behavioral therapy (FBT) o Family systems therapy … due to peer deviance  Behavioral health treatments  Pharmacologic treatments  Recovery support  … Maintenance treatments for opiate -dependent adolescents. … Ecological family therapy: a family-focused therapy approach that expands the boundaries of treatment
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine_protocol-appendix_20111103.pdf
    November 03, 2011 - OBSTRUCTIVE AIRWAY DISEASES R03DC Leukotriene receptor antagonists ATC code - The Anatomical Therapeutic … Solvay Pharmaceuticals|Nektar Therapeutics Sorlandet Hospital HF St. … The EMMES Corporation TorreyPines Therapeutics UCB, Inc. … NCT00665236 Craniosacral Therapy in Migraine: A Feasibility Study NCT00714727 Set Point Acupuncture … NCT00599586 Randomized Controlled Trial of Treating Migraine With Acupuncture NCT00901862 Magnetic Therapy
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-update_executive.pdf
    August 01, 2014 - Individual goals for treatment vary for different children and may include combinations of therapies … context, components of multicomponent therapies that drive effectiveness, and predictors of treatment … the individual providing the therapy? … within a single treatment or across treatments? … setting Functional outcome outside the treatment setting 3 4 1 2 5 Individual and therapeutic

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