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  1. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … Helminthic therapy (pig whipworm) for treatment-resistant ulcerative colitis No high-impact potential … POEM was ineffective in three patients because of severe submucosal fibrosis attributed to previous therapies … Finally, one expert representing a clinical perspective stated that no therapies are available to promote
  2. Anxiety in Children (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/anxiety-children_research-protocol.pdf
    September 12, 2016 - patient-centered outcomes, including remission, anxiety symptoms, behavioral problems, parent distress, therapeutic … Child Interaction Therapy § Problem solving therapy (PST) § Third wave (Mindfulness) therapies • … Child Interaction Therapy § Problem solving therapy (PST) § Third wave (Mindfulness) therapies • … wave (Mindfulness) therapies o Acceptance and Commitment Therapy o Mindfulness Based Cognitive … , Achenbach Child Behavior Checklist), parental overprotection, accommodation, parent distress, therapeutic
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_executive.pdf
    January 01, 2011 - test is usually determined by its indirect effect on outcomes, that is, through its influence on therapeutic … regimen (i.e., repletion or continuous treatment) • Interactions between treatments (i.e., patients … – Most of the reported harms were attributed to iron therapy. Key Question 3. … technical and clinical validity, to the assessment of test impact on clinicians’ diagnostic thinking and therapeutic … regimen (i.e., repletion or continuous treatment) – Interactions between treatments (i.e., patients
  4. effectivehealthcare.ahrq.gov/sites/default/files/infectiousdisease_hi_impact.pdf
    December 01, 2013 - As the first class of new therapies for HCV treatment in 20 years and the first class of direct-acting … used only after other treatments fail … As the first class of new therapies for HCV-infection treatment in 20 years and the first class of … treatments would significantly shift treatment or management models. … therapy was five prior to treatment.
  5. Slide 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/johnson_-ahrq-mcda-presentation.pdf
    August 27, 2012 - Institute. www.rti.org The Use of Conjoint Analysis to Elicit Patient Preferences in Selecting Treatment …  Preferences among treatment alternatives depend on the relative importance of features. …  Respondents state preferences for series of constructed, hypothetical treatment alternatives … A Treatment B PAIN STIFFNESS STOMACH PROBLEMS Occasional mild … Patients rank toxicity against progression-free survival in second-line treatment of advanced renal
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0075_03-10-2009.pdf
    January 01, 2009 - The nominator specifically mentions Remicade, Imuran, anti-inflammatories, and biologic therapies for … the treatment and management of Crohn’s disease. … Comparator(s): Comparisons of the above pharmacologic treatments. … What treatments or therapies, alone or in conjunction with one another, provide the highest rate of … , and the person’s response to previous medical treatments.
  7. effectivehealthcare.ahrq.gov/sites/default/files/13_pulmonary_potential_high_impact_june_2012.pdf
    January 01, 2012 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , reduce complications of therapy, and allow patients to initiate therapy sooner, which could slow …  Key Facts: Current therapies for CF have improved median survival times, but patients with CF … therapy, and chest therapy, if the drug halts disease progression. … United Therapeutics products. [internet].
  8. effectivehealthcare.ahrq.gov/products/asthma-nonpharmacologic-treatment/thermoplasty-systematic-review
  9. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
    January 01, 2012 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … New drug treatment options are needed for obese patients seeking medical therapy for weight loss. … with antiobesity pharmacotherapies and potential third-party payers’ unwillingness to cover these therapies … Goods Administration for inclusion in its therapeutic goods registry for treating T2DM and obesity
  10. effectivehealthcare.ahrq.gov/sites/default/files/considerations-for-statistical-chapter-10.pptx
    January 01, 2013 - and is also unrelated to the confounders of the treatment-outcome relationship. … be used to essentially back out the effect of the treatment on the outcome. … However, difficult issues arise when both treatment and confounding variables vary over time. … The IPTW technique assumes that, at each treatment decision, the effect of treatment on the outcome is … unconfounded, given the past covariate and treatment history.
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0262_05-11-2007.pdf
    January 01, 2007 - What constitutes an adequate diagnostic evaluation on which to base treatment of UI? 2. … How effective is pharmacologic treatment of UI? 3. … How effective is non-pharmacologic treatment of UI? 4. … Does site of care (office, hospital, nursing home) influence choice of best treatment? 5. … Does this make a clinical difference in response to treatment? 8.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0215_01-06-2010.pdf
    January 01, 2010 - Document Completion Date: 8-13-10 1 Results of Topic Selection Process & Next Steps  Treatment … Nominator: Individual Nomination Summary: The nominator questions whether there are any effective treatments … No recent systematic review or practice guidelines were identified that address the treatment of RLS … Because of the numerous treatments that are FDA approved or available off-label for this condition, … any harms of these treatments, particularly in specific subpopulations such as elderly patients.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_clinician.pdf
    May 01, 2016 - Psychological and behavioral therapy interventions include cognitive behavioral therapy (CBT), interpersonal … psychotherapy (IPT), and dialectical behavior therapy (DBT). … BWL therapy 2 170 BWL decreased BMI more than CBT at the end of treatment. ��� CBT decreased binge-eating … was likely managed by a psychiatrist and psychological and behavioral therapy treatments were likely … Behavioral weight-loss therapy Treatment that incorporates various behavioral strategies, such as caloric
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0587-131115.pdf
    March 06, 2013 - Individuals with non-muscle invasive bladder cancer (stages Ta, T1, and Tis) Intervention(s): Intravesical therapies … cystoscopy approaches in the detection and management of NMIBC Comparator(s): Various new and existing therapies … Initial treatment for this stage of bladder cancer usually involves surgical removal of the tumor through … a cystoscope (called TURBT) followed by adjuvant therapy Approximately a quarter of these cases will …  There have been recent advances in the diagnosis, treatment, and management of the NMIBC.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0440_06-01-2011.pdf
    January 01, 2011 - Staff-Generated PICO Population(s): Cancer patients completing primary treatment, including adults … cancers, with the potential for improved survival; improvement in quality of life and health due to treatment … of late or continuous treatment side effects or psychosocial effects of having cancer; greater patient … Harms: Earlier initiation of treatment for cancer progression that does not increase survival (thereby … shortening the asymptomatic period with no side effects of treatment); more frequent screening with
  16. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … , noting its potential to improve patient adherence to therapy recommendations and simplify treatment … taking an injectable therapy (e.g., insulin). … A pathway to endoscopic bariatric therapies. Gastrointest Endosc. 2011 Nov;74(5):943-53.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_executive.pdf
    January 01, 2016 - success Nonressolution of lesions Adjuvant or replacement therapies or agents KQ2 KQ3 5 … These 148 studies included 42 comparative studies, 38 addressing effectiveness and harms of therapiestherapy is more effective than propranolol alone. … Effectiveness and Harms of Second-Line Therapies Following Beta-Blockers or Corticosteroids We did … since the advent of beta-blocker treatment in countries, like the United States, where such treatments
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0365_10-28-2010.pdf
    January 01, 2010 - The nominator expressed interest in how the effectiveness of treatments may differ by factors such as … initiation, patient preferences and therapeutic values, and demographic characteristics; and whether … psychotherapy (including groupings of trauma-focused vs. not), to include complementary and alternative therapies … pharmacotherapy, general and specific types of psychotherapy (including complementary and alternative therapies … initiation, patient preferences and therapeutic values, and demographic characteristics).
  19. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … No effective treatments are available to improve long-term nutritional absorption other than intestinal … is refractory to current therapies, the experts agreed. … Endoscopic therapies for gastroesophageal reflux disease (GERD). Policy number: 2012T0322K.
  20. Topic-Brief3-Sud (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief3-SUD.pdf
    April 01, 2021 - Food and Drug Administration for treatment of opioid use disorder include maintenance therapy with the … options include psychological therapies (e.g., cognitive behavioral therapy, contingency management … These therapies aim to address behavioral aspects of the underlying substance use disorder, improve … treatment. … Managing chronic pain in the elderly: an overview of the recent therapeutic advancements.

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