-
effectivehealthcare.ahrq.gov/sites/default/files/mcda-ijzerman.pdf
January 01, 2011 - The pattern of choices reveals the implicit decision weights
patients attach to therapeutic benefits … , harms, processes and costs that describe
the treatment profiles (ISPOR taskforce, 2012)
Slide … The top object labeled
Decision objective (treatment) is linked to objects below labeled Criterion 1 … Under the title ‘Compare the relative importance with respect to: Goal: Select best drug
treatment … This screen is titled: Goal: Select the best drug treatment.
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
April 01, 2012 - new (and new uses of existing) pharmaceuticals, medical devices,
diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery
innovations that address … that does not
respond to current therapies. … Available:
http://www.cff.org/treatments/CFCareGuidelines/.
28. Expert Commenter 400. … ReleaseID=616097
http://www.cff.org/treatments/CFCareGuidelines/
-
effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_june_2012.pdf
January 01, 2012 - Many patients with T2DM do not meet treatment goals and require additional therapy
with one of two … Adherence
Key Facts: Two therapies are in development for treating T2DM to improve efficacy, … for T2DM, especially potentially curative treatments such as bariatric surgery. … One expert with a clinical perspective
also noted that initiation of treatment with this therapy might … Both treatments
were generally well tolerated.
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1306.pdf
January 01, 2016 - Many
patients with T2DM do not meet treatment goals and require additional therapy with one of two … Some patients with T2DM also
need insulin therapy, but most undergo treatment with pharmacotherapy … Other treatment options, such as anti-VEGF therapies are available for treating DME, and
according … (e.g., anti-VEGF therapies). … Intarcia Therapeutics. A study to evaluate ITCA
650 for the treatment of type 2 diabetes.
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
June 01, 2015 - , screening and diagnostics, therapeutics, surgery, programs, and
care delivery innovations that address … Effective treatments are needed. … Patients with AS who did not respond to prior treatment with
TNF therapies showed significant improvement … Secukinumab (Cosentyx) for Treatment of Psoriatic Arthritis
Key Facts: Current treatments for PsA … Clinical Pathway at Point of This Intervention
AS treatment focuses on physical therapy and exercise
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0334_08-04-2010.pdf
January 01, 2010 - Selection Process & Next Steps
Pharmacogenetic testing for CYP2C19 variants for guiding antiplatelet treatment … Intervention(s): Genetic testing for CYP2C19 variants to guide treatment selection. … Because this is a comparison of testing strategies, there exist several treatment options
that may be … Note that a no-testing strategy
implies treatment following the current guidelines (i.e., clopidogrel … antiplatelet therapy for the prevention of major adverse
cardiovascular outcomes, compared to alternative
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-update_research-protocol.pdf
August 18, 2016 - Nonpharmacologic therapies (e.g., behavioral
therapy, psychotherapy, psychosocial interventions, and … KQ 2: Specific treatments will be compared to other treatments
as described above or to no treatment … ] OR "Vitamins/therapeutic
use"[MeSH] OR "Food Additives/adverse effects"[MeSH] OR "Probiotics/therapeutic … )"[MeSH] OR "Complementary Therapies"[MeSH] OR "Combined Modality
Therapy"[MeSH] OR "psychosocial therapy … ] OR "alternative therapy"[tiab] OR "alternative therapies"[tiab] OR "Interpersonal
skills training"
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
April 01, 2015 - to definite MS, while only 7 with normal
baseline MRI converted.5
MS cannot be cured with current therapies … Analytic framework for discontinuing disease-modifying treatments for MS
DMT = disease-modifying treatment … Factors related with treatment
adherence to interferon beta and glatiramer acetate therapy in
multiple … Factors leading
patients to discontinue multiple sclerosis therapies. … Country, sex, EDSS
change and therapy choice independently predict treatment
discontinuation in multiple
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0128_07-01-2009.pdf
January 01, 2009 - of Topic Selection Process & Next Steps
Generic versus brand name antiepileptic drugs for the treatment … of epilepsy will be addressed as part
of a larger in-process systematic review on treatment of epilepsy … Nomination
Summary:
The nominator is interested in the use of generic medications for the treatment … In addition, many states include these drugs in their narrow
therapeutic index laws. … The EHC Program has
initiated a systematic review of epilepsy treatment which will include the issue
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
January 01, 2023 - , including opioid therapy, nonopioid
pharmacologic therapy, and nonpharmacologic therapy. … Interventions
• Research to identify effective
nonpharmacologic therapies for neuropathic
pain. … • Knee osteoarthritis: Exercise, cognitive
behavioral therapy (CBT). … • Hip osteoarthritis: Exercise, manual therapies. … to clarify the effectiveness of vertebroplasty,
specifically whether some sham interventions have
therapeutic
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1306.pdf
July 01, 2013 - new (and new uses of existing) pharmaceuticals, medical devices,
diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care
delivery innovations that address … , noting its potential to improve patient adherence to therapy recommendations and
simplify treatment … pharmaceutical companies continue to
search for novel approaches to safe and effective weight-loss therapeutics … A pathway to endoscopic bariatric therapies.
Gastrointest Endosc. 2011 Nov;74(5):943-53.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0136_07-21-2009.pdf
January 01, 2009 - -12-10
1
Results of Topic Selection Process & Next Steps
Nonsurgical and surgical treatment … interested in the comparative effectiveness of nonsurgical (including
pharmacologic and behavioral treatments … ) versus surgical (mainly hysterectomy with or
without oophorectomy) for the treatment of chronic pelvic … including hysterectomy with or without oophorectomy
Comparator: Nonsurgical treatments including pharmacologic … There are a number of surgical and nonsurgical treatments
available for the treatment of chronic pelvic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
August 01, 2012 - ,4 the annual costs of modern
therapies can range from $50,000 to
$125,000 per patient.5,6
In PCDs … • Does the use of the SFLC assay influence the type of
treatment (e.g., radiation therapy)?
KQ4. … Another study, of
B quality, found that after 2 months of therapy, treatment
response was achieved … The studies varied in their inclusion criteria
and treatments analyzed, as well as in the proportions … the
assay for the diagnosis of PCDs and the adjunctive and
independent role of the assay in making therapeutic
-
effectivehealthcare.ahrq.gov/sites/default/files/s50.pdf
October 01, 2007 - , and therapies); and (3) multiple outcome mea-
surements. … Examples include which drugs are dispensed, which
dose is used, which nutritional therapies are used … and for how
long, or which physical therapy activities/interventions are
used and for how long. … It took between 0.5 and
2 minutes to fill this out for each physical therapy session. … Also,
participation in higher-order or more difficult therapeutic
activities seemed to improve lower-level
-
effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
January 01, 2012 - new (and new uses of existing) pharmaceuticals, medical devices,
diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery
innovations that address … (Contrave
®
, Orexigen Therapeutics, Inc., La Jolla, CA in
collaboration with Takeda Pharmaceutical … New drug treatment options are needed for
obese patients seeking medical therapy for weight loss. … Goods Administration for inclusion in its therapeutic goods registry for treating T2DM
and obesity
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-child-adolesc-mental-health-grand-rounds.pptx
May 22, 2025 - Little evidence that combination therapies of medication plus psychosocial therapies produce better results … Most of these treatments involve multiple treatment strategies and components (e.g., family, parent, … Cognitive Behavioral Therapy (CBT)
Outpatient treatments that are based on the view that suicide attempts … No evidence for brief web or video interventions; adjunct treatments; phone calls
Treatment developers … Psychosocial interventions were diverse and involved multiple therapeutic components.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_disposition-comments.pdf
November 27, 2012 - The rate of complications are as high as
for some therapeutic or preventive procedures (e.g. radical … If therapies are indeed found
in the long term to be more effective and less toxic than earlier therapies … Further therapeutic advances currently far along in development promise to
transform the HCV landscape … largest bottleneck, and a revolution in screening
guidelines must accompany the revolutions in therapeutics … the CDC’s forthcoming revision to its HCV screening guidelines, as well as further diagnostic
and therapeutic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_clinician.pdf
June 01, 2016 - ) and surgical
interventions (such as laser therapy or excision in appropriate
cases). … PDL therapy
only fades IH lesions and does not stop their proliferation. … alternative or
adjunctive therapies are appropriate after first-line treatment
is unsuccessful, and … Overall, the role of laser therapy in
treating IH lesions is not clearly described in the literature … corticosteroid therapies were unsuccessful.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
December 01, 2012 - group (i.e., comparison
of different treatments, hormonal vs. surgical therapy,
or treatment vs. no … Effectiveness of Hormone Therapy
Fourteen studies in 19 publications assessed hormonal
therapy in treatment … Effectiveness of Surgical Treatments
Twenty-six studies addressed surgical treatment. … This
report reviews the literature on treatment planning and
therapeutic interventions to achieve these … Strength of evidence of surgical treatments for cryptorchidism
Outcome Treatment
Number of Studies;
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
March 19, 2018 - If all patients adhered 100% to
therapy, intermittent therapy and the need to add
more and more controllers … This review is focused on the
class comparison of these
therapies. … include
patients 6 years old and above BI appreciates
AHRQ’s thorough review of currently available
therapeutic … The results “no difference” means
that statistically, there was no
difference in the two therapies … We avoid using terms
such as “similar” so as not to
convey equivalence of therapies.