-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rtc-design-principles_research.pdf
January 01, 2009 - Test-treatment pathway
Treatment effects. … more sensitive test, just as they are needed to assess the
efficacy of new treatments. … Results of conservative surgery
and radiation therapy for multiple
synchronous cancers of one breast … Standard for breast conservation
therapy in the management of
invasive breast carcinoma. … The role of before-after studies
of therapeutic impact in the
evaluation of diagnostic technologies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
September 01, 2011 - as
therapies for patients with TRD: electroconvulsive
therapy (ECT), repetitive transcranial magnetic … Comparisons of these nonpharmacologic
therapies are our main interest. … How do the efficacy, effectiveness, or
harms of treatment with nonpharmacologic
treatments for TRD differ … Direct comparisons of treatment strategies, holding
consistent any coexisting or concomitant therapies … When
ongoing treatment is uncontrolled and reflects a variety
of treatments—e.g., some patients continue
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/instrumental-variable-methods_research.pdf
April 01, 2010 - Example 2: The Hospital Formulary
Suppose that a new thrombolytic therapy is introduced for the treatment … The new medication is thought to be more effective than existing
therapies, but it is expensive and … Thus, providers who preferentially use one
treatment must not also preferentially use other treatments … For
example, in effectiveness studies, underuse of a therapy results in the IV up-weighting the
treatment … Estimating probit models with self-selected
treatments. Stat Med 2006;25:389-413.
63.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_disposition-comments.pdf
September 01, 2011 - Therefore it is good that this report includes trials
comparing to controls, sham therapies and pharmacological … The study
compares baseline and post-treatment
outcomes after electroconvulsive therapy. … Their call for action, such as
more uniformity in diagnosis and in therapeutic protocols, is well
thought … patient receiving
long-term dynamic therapy was better off than 96% of patients
receiving other treatments … Cognitive
therapy versus medication in augmentation and switch strategies as
second-step treatments
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0495_05-24-2013.pdf
January 01, 2013 - Treatment options for
metastatic breast cancer include hormone therapy and chemotherapy as well as radiation … therapy
and/or surgery for pain relief … bone scintigraphy, CT, MRI, x-ray, ultrasound, PET/CT and FDG-
PET can be used to assess response to therapy … , the results of which may affect treatment strategies
and outcomes. … A variety of techniques may be used based on treatment strategy and location of
metastases.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0351_05-10-2010.pdf
January 01, 2010 - and associated abnormalities and their impact on treatment and
outcomes. … cryptorchidism (undescended testicle)
Intervention(s): diagnostic methods (imaging, laparoscopy), hormone therapy … , surgical
therapy, specific surgical techniques, early treatment, follow-up care, counseling of
patient … of
treatment, medical therapies, different surgical techniques
Outcome(s): diagnostic ability … uncertainty regarding appropriate
diagnostic approaches for cryptorchidism as well as appropriate therapeutic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypothyroidism-hyperthyroidism-screening-treatment_research-protocol.pdf
March 11, 2010 - This uncertainty impacts the decision-making for clinicians who are considering
treatments for subclinical … or
other acceptable options of thyroid replacement therapy, and may include inclusion of
activities … Adverse reactions are usually due to therapeutic overdosage and
resulting hyperthyroidism. … OR 1-9
11. therapeutic use [sh]
12. treatment [tiab]
13. therapy [tiab]
14. … OR clinical trial[Publication Type] OR random*[Title/Abstract] OR
random allocation[MeSH Terms] OR therapeutic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
January 01, 2015 - Treatment
components may include drugs, exercise programs,
cognitive behavioral therapy (CBT), patient … Pharmacologic Therapies
The majority of included studies reported the effects of
pharmacologic therapies … Psychological Therapies
Four studies examined the effects of psychological
therapies in subgroups of … Mixed Types of Treatments
Four studies assessed combination therapies, and each
study had high risk … Multidisciplinary treatment
of fibromyalgia: does cognitive behavior therapy increase the
response
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0352_09-22-2010.pdf
January 01, 2010 - Date: 03-19-12
1
Results of Topic Selection Process & Next Steps
Perinatal depression treatment … of depression with antidepressants and other therapies during preconception
and pregnancy. … with antidepressants; use of other treatments, including cognitive behavioral therapy,
other counseling … Potential harms and benefits of depression treatment must be weighed against the potential
harms of … A review addressing perinatal depression treatment will be a good companion to an in-process
-
effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1512.pdf
January 28, 2016 - new (and new uses of existing) pharmaceuticals, medical
devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care
delivery innovations that address … Sovaldi and Sovaldi combination therapies. … of This Intervention
No FDA-approved vaccines or antiviral agents exist for EVD, although several therapeutic … SVR12 was 76% in patients naïve to treatment after 8 weeks of
therapy.
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1306.pdf
October 01, 2014 - Overall high-impact potential: deep brain stimulation (Reclaim DBS Therapy or
Libra DBS) for treatment-resistant … and psychotherapy as first- and
second-line therapies and electroconvulsive therapy or repetitive … They cited suboptimal current treatments, lack of an FDA-approved
treatment for this condition, and … DBS therapy is incompatible with some other device-
based depression treatments. … of Psychotic Depression
Deep Brain Stimulation (Reclaim DBS Therapy or Libra DBS) for Treatment-Resistant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/binge-eating_executive.pdf
December 01, 2015 - includes the influence of other patients
suffering from the condition in the therapeutic process. … .70-72
Behavioral Interventions: Inpatient Treatment Versus
Inpatient Treatment Plus Active Therapies … treatments for BED patients are
pharmacological agents and therapies that combine
psychological and … Multivariate
therapeutic approach to binge-eating disorder: combined
nutritional, psychological and … Binge eating disorder in
obesity: comparison of different therapeutic strategies.
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes_hi_impact.pdf
March 01, 2012 - Many patients with T2DM fail to meet treatment goals and require additional
therapy with one of two … One expert with a clinical perspective also noted that
initiation of treatment with this therapy might … Both treatments
were generally well tolerated. … compliance
Experts agreed that while any new therapy for the treatment of diabetes would be welcome … of T2DM
Intervention
SGLT2 inhibitors for treatment of T2DM
While many current treatments help
-
effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1506.pdf
December 01, 2015 - The high cost of emerging HCV therapies combined with the
large population of patients requiring treatment … SVR12 was 76% in
patients naïve to treatment after 8 weeks of therapy. … The high cost of emerging HCV therapies
combined with the large population of patients requiring treatment … Janssen Therapeutics. … Titusville (NJ): Janssen Therapeutics;
2014 Nov. 44 p.
-
effectivehealthcare.ahrq.gov/sites/default/files/ebc-challenge-1stplace-qrmedica.pdf
January 01, 2013 - Patients and
guardians can use the patient education tools to understand proper diagnosis and treatment … A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions … A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions … A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions … Key Elements of Treatment
Evidence shows that success with treatment of ROM with long-term antibiotics
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
December 09, 2009 - are looking for other options beyond pharmacologic therapy. … of a biologic intervention), do non-pharmacologic interventions such as
electroconvulsive therapy (ECT … How do these non-pharmacologic treatments compare with pharmacological
treatments in efficacy or effectiveness … How do the efficacy, effectiveness, or harms of treatment with non-pharmacologic treatments
for treatment-resistant … New treatments without a current
evidence that require further research, such as Magnetic Seizure Therapy
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_executive.pdf
April 01, 2013 - Effectiveness Reviews,
the program supports systematic
appraisals of existing scientific
evidence regarding treatments … Review
Number 113
Effective Health Care Program
2
The development of intensified antineoplastic therapies … How do different criteria for
discontinuing therapy or for optimal duration of
therapy compare regarding … Criteria for Discontinuing Therapy or for Optimal
Duration of Therapy
No randomized controlled trials … or defining optimal duration of
therapy.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
August 01, 2013 - treatments. … oxygen therapy
• Complementary and alternative medicine therapies: Gingko biloba extracts;
acupuncture … therapy
Combination Therapies
• Any combination of tinnitus interventions (e.g., pharmacological treatment … with cognitive behavioral therapy)
KQ3: Any treatment/therapy used to reduce/help/cope with tinnitus … Acceptance and
commitment therapy versus tinnitus retraining therapy in the
treatment of tinnitus:
-
effectivehealthcare.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
January 01, 2012 - , screening and diagnostics, therapeutics, surgery, programs, and care
delivery innovations that address … Patients sometimes also use
alternative therapies. … , Germany), is being used by some clinicians and
patients as a nonsurgical therapeutic alternative … nonsurgical therapeutic alternative for
patients with treatment-refractory disease. … Some noted that this treatment is priced less expensively than some currently approved
UC treatments
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0367_11-08-2010.pdf
January 01, 2010 - Results of Topic Selection Process & Next Steps
Efficacy and safety of screening and treatment … for depression
Comparator(s): Different approaches to screening and treatment, including different … primary care),
various screening tools, medication, cognitive, individual or group, and hormonal
therapies … For women in the postpartum period, what is the effectiveness and safety of
screening and treatment … targeted screening, timing of screening interventions, screening instruments,
intervention settings, and treatments