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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_executive.pdf
    April 01, 2012 - Duloxetine resulted in improved UI in 75-140 women per 1,000 treated, while 129 women per 1,000 treated … Oxybutynin resolved UI in 114 women per 1,000 treated (95% CI, 64 to 163), while 63 women per 1,000 … treated (95% CI, 12 to 127) discontinued oxybutynin because of adverse effects. … treated (95% CI, 47 to 120) experienced adverse effects. … treated (95% CI, 118 to 260) experienced adverse effects.
  2. effectivehealthcare.ahrq.gov/sites/default/files/cer-225-substance-abuse-adolescents-evidence-summary%20225%20Substance%20Use%20Adolescents.pdf
    May 01, 2020 - When left untreated or ineffectively treated, adolescents with substance use disorders are at risk of … The pervasive negative consequences associated with untreated or ineffectively treated adolescent
  3. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
    April 01, 2012 - expert comments were collected for this report indicated that patients with severe persistent asthma treated … They also reported that 79% of patients treated with BT and 64% of patients treated with sham achieved … Six percent more BT-treated patients were hospitalized during the treatment period (up to 6 weeks after … annual meeting of the American Thoracic Society stated that patients with severe refractory asthma treated … Patients treated with ivacaftor also demonstrated a significant improvement in quality of life (p <
  4. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
    January 01, 2007 - influenced by retrospective cohort studies, where medication discontinuation rates were higher in ACEI-treated … adverse events, in which the NNT is on the order of 27—that is, 1 more withdrawal per 27 patients treated … Angioedema was reported only in patients treated with ACEIs; however, because angioedema was rarely
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_executive.pdf
    April 01, 2013 - There was one additional death for every 59 treated patients when the control arm on-study mortality … was 10 percent, and there was one additional death for every 588 treated patients when the control … interval; RR = relative risk 5 Rates of thromboembolic events were consistently higher in ESA-treated
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_executive.pdf
    January 01, 2014 - First, all patients presenting with UA/NSTEMI are treated with an initial dose of aspirin, followed … In patients treated for UA/NSTEMI after hospitalization (postdischarge): a. … patients and heparin-treated patients (low SOE) … patients (4.1% and 11.2%) vs. heparin-treated (5.7% and 12.5%) Major bleeding at 30 days SOE = High … >12 months) showed similar rates across treatment groups in both DES-treated and BMS-treated populations
  7. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
    January 01, 2007 - Radiographic changes were not different for those treated with leflunomide and those treated with sulfasalazine … Radiographic outcomes, however, were statistically significantly better in patients treated with biologic … Patients treated with initial combination therapy of methotrexate, sulfasalazine, and tapered high- dose … Investigators may find large registries helpful in identifying the same kinds of patients treated with … The group treated with biologics had poorer baseline characteristics than the methotrexate group; once
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_policymaker.pdf
    August 01, 2016 - Health care utilization studies* report reduced medical costs among patients treated with AUD medication … when compared with patients treated without it.2 A meta-analysis of three health care utilization
  9. effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1506.pdf
    December 01, 2015 - Patients treated for 12 weeks had an SVR12 of 95%. … The SVR12 rate for patients treated with Harvoni with or without RBV for 12 weeks was 94% and 96%, … In patients treated with or without RBV for 24 weeks, 99% in both groups achieved SVR12.24 … In patients treated for 12 weeks, 92% achieved SVR12; in patients treated for 24 weeks, 96% achieved … Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
    January 01, 2015 - Key Questions This systematic review examined whether specific subgroups would benefit from being treated … presented for within-stratum results—such as stratum-specific change in pain for those with MDD (treated … vs. controls) and for those without MDD (treated vs. controls)—we report within-stratum information … Study authors noted similar improvements in PGI-I in treated patients versus controls regardless of … patients with MDD relative to treated adults without MDD.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_disposition-comments.pdf
    July 08, 2014 - There are few studies that compare outcomes in depressed untreated and depressed treated women. … Text at the beginning of the paragraph changed to: “Evidence on harms to the child of a mother treated … It underscores the fundamental need for better characterization of the population being treated and … studied, e.g. whether women are being treated with an antidepressant due to depression, as well as … Were the treated mothers symptom-free, or did they still have clinical depression?
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
    May 01, 2015 - Treatment Strategies Ankyloglossia may be treated with surgical or nonsurgical approaches. … The one poor-quality RCT comparing surgical methods reported improved articulation in patients treated … One poor-quality RCT reported improved articulation in patients treated with Z-frenuloplasty compared … Longer term followup of both treated infants and controls is needed. … Larger studies that assess both treated and untreated individuals could provide useful data to minimize
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-summary.pdf
    November 01, 2023 - Compared with placebo, study participants treated with acamprosate were more likely to experience anxiety … In head-to-head studies, patients treated with acamprosate had a slightly lower risk of headache and … vomiting than those treated with naltrexone.
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiotherapy-proton-beam_research.pdf
    May 01, 2012 - A requirement (for some indications) that the patient be treated as part of a clinical trial. 4. … Figure 2: Growth in number of beneficiaries treated with proton beam radiotherapy by facility, … However, from 2006 to 2009, the number of beneficiaries treated increased from about 740 to almost 1,200 … Over this same period, the number of beneficiaries treated for conditions of possible benefit (Group … However, many are being treated for tumors for which there is far less consensus about this therapy's
  15. effectivehealthcare.ahrq.gov/products/autoimmune-disease/rapid-research
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections-surveillance-140925.pdf
    January 01, 2014 - Of 339 alcohol-treated stool samples cultured on IDCd media and five other selective agars, C. diff … with fidaxomicin, 62 treated with vancomycin fidaxomicin (200 mg twice daily) vs. … patients treated with fidaxomicin (-15.8% difference, 95% CI: -30.4% to -0.3%l P=0.045). … treated with fidaxomicin (P=0.003). … In comparison with vancomycin-treated patients, fidaxomicin-treated patients had reduced acquisition
  17. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - Patients treated with azithromycin were reported to have a longer median time to the first exacerbation … and less-frequent exacerbations than patients treated with placebo. … Additionally, investigators noted concern about antibiotic-resistant bacteria in patients treated with … Patients treated with ivacaftor also demonstrated a significant improvement in quality of life (p<0.001 … time to first exacerbation was 266 days (95% confidence interval [CI], 227 to 313) among patients treated
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
    November 01, 2017 - Question 3: For patients with confirmed or suspected opioid overdose in out-of-hospital settings treated … opioid overdose who exhibit altered mental status, miosis, or respiratory depression and who are treated … dosing strategies in EMS personnel – For Key Questions 1 and 1a, also include studies of patients treated … Question 3: For patients with confirmed or suspected opioid overdose in out-of-hospital settings treated … Assessment for deaths in out-of-hospital heroin overdose patients treated with naloxone who refuse
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_surveillance.pdf
    January 15, 2013 - dietary control (IDC) of Phe on pre-attentive processing in children with early and continuously treated … Phe levels were reduced by at least 30 percent in up to half of treated participants (32 to 50 percent … Pre-attentive processing in children with early and continuously-treated PKU. … The neuropsychological profile of early and continuously treated phenylketonuria: orienting, vigilance … Phe levels were reduced by at least 30 percent in up to half of treated participants (32 to 50 percent
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
    November 01, 2014 - immunocompetent patients.1,5 Because HAP, VAP, and HCAP share similar microbial sources, they are treated … guide dosing of antibiotics have important implications, not only for the individual patient being treated … for this review include adults who have presumed or confirmed HAP, VAP, or HCAP and who are being treated … HAP had to have begun in a health care setting (e.g., skilled nursing facility) and be treated in the … Clinical cure of ventilator-associated pneumonia treated with piperacillin/ tazobactam administered

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