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  1. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/11_peptic_ulcer_potential_high_impact_2012-12-111.pdf
    January 01, 2012 - In this report, three case series of patients with achalasia treated with POEM were highlighted ( … Phase III trials reported that patients with SBS treated with teduglutide can significantly reduce … Additionally, a long-term extension trial demonstrated that some patients treated with teduglutide … with POEM, investigators reported that 98.5% of patients were successfully treated. … Additionally, estimated blood loss was less in patients treated with POEM (≤10 mL in all cases vs.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nomination-apbi-breast-cancer.pdf
    April 01, 2017 - Other series similarly showed a 0% 5-year IBTR risk among 32 women with DCIS treated with multicatheter … Although there was no statisti- cally significant difference in IBTR risk for patients treated with IORT … A pooled analysis of outcomes for 300 patients with DCIS treated with APBI. … Outcomes in women treated with MammoSite brachytherapy or whole breast irradiation stratified by ASTRO … A retrospective analysis of patients treated at the European Institute of Oncology.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0648-140819.pdf
    June 24, 2014 - differ according to characteristics of (joint/ gout/systemic) In adults with a history of gout being treated … The diagnostic accuracy of clinical signs and symptoms is uncertain. § Gout is treated by both nonpharmacologic
  4. effectivehealthcare.ahrq.gov/sites/default/files/adhd_executive.pdf
    October 01, 2011 - By the end of the 1960s, approximately 150,000 to 200,000 children were treated with stimulants, which … While ADHD can begin before children enter school, it is most commonly identified and treated in primary … For KQ3, the population includes people of any age who have been diagnosed with ADHD or treated for … Symptomatic improvement in children with ADHD treated with long­ term methylphenidate and multimodal … The MTA at 8 years: prospective follow­up of children treated for combined­type ADHD in a multisite
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
    January 01, 2007 - Among patients treated with medical therapy alone, there is the risk for deterioration of kidney function … We included peer reviewed primary studies of adult patients treated for ARAS and excluded studies that … Only the retrospective study found that patients treated with angioplasty (with or without stent) had … a lower mortality rate than those treated medically;17 however, the medically treated patients were … medically (–10/–2 mm Hg) than those treated with angioplasty (–2/–2 mm Hg); although this difference
  6. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - Phase III trials reported that patients with SBS treated with teduglutide can significantly reduce … with POEM, investigators reported that 98.5% of patients were successfully treated. … Additionally, estimated blood loss was less in patients treated with POEM (10 mL or less in all POEM … of infusion days per week by 1 or more days, compared with 23% of patients treated with placebo … Two patients treated with teduglutide 0.05 mg/kg/day were weaned from PN support by week 24.65 In
  7. effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
    January 01, 2012 - a long-term injectable, the degree of misclassification may be significantly larger for patients treated … In addition, performing both an as-treated analysis (where patients are censored at the end of the … For other diseases like cancer, early-stage disease may be treated with surgical procedures, whereas … more advanced disease may be treated with chemotherapy and/or radiation or combinations of multiple … Cancer risk in patients with rheumatoid arthritis treated with anti–tumor necrosis factor a therapies
  8. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label_executive.pdf
    January 01, 2007 - In the second trial, more risperidone-treated than placebo-treated children improved on that subscale … weight gain of 1.0, 0.7, and 0.4 pounds while on treatment, compared to a weight loss among placebo-treated … This risk was equivalent to 1 additional stroke for every 31 patients treated in this patient population … Cognitive disturbance and psychotic symptoms were more common in olanzapine-treated patients than in … While the increased risk of death in elderly dementia patients treated with atypical antipsychotics was
  9. effectivehealthcare.ahrq.gov/sites/default/files/09_infectiousdisease_potential_high_impact_june_2012.pdf
    January 01, 2012 - than patients treated with usual care. … than patients treated with usual care (beta = 19.3; 95% CI, 10.9 to 27.6; p<0.001). … Patients treated with FMT had a mean time to resolution of diarrhea of 6 days. … Two of these patients were successfully treated again with FMT. … with another FMT, and two were treated with antibiotics for CDI.
  10. effectivehealthcare.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
    March 24, 2017 - Otherwise, typical opioids are considered to be equivalent in efficacy for pain and have been treated
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetic-neuropathy-disposition-170707.pdf
    March 24, 2017 - Otherwise, typical opioids are considered to be equivalent in efficacy for pain and have been treated
  12. effectivehealthcare.ahrq.gov/sites/default/files/study-design-considerations-chapter-2.pptx
    January 01, 2013 - With confounding by frailty, frail patients (close to death) are less likely to be treated with preventive … Confounding by frailty arises because frail patients (close to death) are less likely to be treated with … effect of treatment versus no treatment on the outcome to the short-term effect of treatment in those treated … http://www.ncbi.nlm.nih.gov/pubmed/7619931 Estimates the immediate effect of treatment in those treated … This observation time is divided into treated person-time, a washout period of person-time, and untreated
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
    January 01, 2007 - Angioedema was reported only in patients treated with ACEIs; however, because angioedema was rarely … ACEIs than in groups treated with ARBs … Twenty-nine studies compared cough in subjects treated with ACEIs and ARBs. … All 29 studies demonstrated higher rates of cough in ACEI-treated participants. … rates in ARB-treated participants; and five showed no difference in withdrawal rates.
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-response-chemotherapy-dental.pdf
    July 01, 2023 - The first was comprised of 190 patients treated in the same time period, and the second was comprised … Six of the patients in the screened group were found to have localized infections that were treated … The participants in these trials were patients with hematological malignancies treated with induction … This evidence comes only from patients with head and neck cancer treated with radiation therapy and … Oral condition in children treated with bone marrow transplantation.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
    April 25, 2013 - ESAs have never been indicated for use in patients treated with radiation therapy. … In the curative treatment setting, in a large trial involving patients with Hodgkin's disease treated … What was the on-study mortality data for chemotherapy only-treated patients? … with curative intent and 9.2 per 1,000 patients not treated with curative intent. … As mentioned above, patients with small cell lung cancer and Hodgkin’s disease treated with specific
  16. effectivehealthcare.ahrq.gov/sites/default/files/01_arthritis_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - In patients with knee OA and a Kellgren-Lawrence status of II, III, or IV (n=23) who were treated with … The investigators reported that patients treated with MSC therapy had improvements in patient pain … Increases in swelling (p=0.03) and pain reaction (p=0.0005) were observed in patients treated with … Flares are treated by increasing DMARD dosages and administering short-term glucocorticoid therapy. … In general, the experts thought that tofacitinib would not shift how RA is treated or managed.
  17. effectivehealthcare.ahrq.gov/sites/default/files/01_-arthritis_potential_high_impact_june_2012.pdf
    January 01, 2012 - In phase III trials, patients treated with tofacitinib demonstrated improvements in signs and symptoms … Increases in swelling (p=0.03) and pain reaction (p=0.0005) were observed in patients treated with … PRP injections. 28 In a retrospective analysis, consecutive patients with primary OA (n=86) treated … Flares are treated by increasing DMARD dosages and administering short-term glucocorticoid therapy. … In general, the experts thought that tofacitinib would not make a large shift in how RA is treated or
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hip-fracture-pain.ppt
    May 01, 2011 - Intervention (Timing) Comparator No. of Trials (Treated, Control) Mean Difference in Pain: Intensity … The difference between treated and control groups for reported intensity of pain is neither clinically … Intervention (Timing) Comparators No. of Studies (Treated, Control) Mean Difference in Pain Intensity … Intervention (Timing) Comparators No, of Studies (Treated, Control) Mean Difference in Pain Intensity … NNT (number needed to be treated to have one additional patient benefit, when compared with usual care
  19. effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain.ppt
    May 01, 2011 - Intervention (Timing) Comparator No. of Trials (Treated, Control) Mean Difference in Pain: Intensity … The difference between treated and control groups for reported intensity of pain is neither clinically … Intervention (Timing) Comparators No. of Studies (Treated, Control) Mean Difference in Pain Intensity … Intervention (Timing) Comparators No, of Studies (Treated, Control) Mean Difference in Pain Intensity … NNT (number needed to be treated to have one additional patient benefit, when compared with usual care
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-quality-indicator-testing_research.pdf
    April 01, 2010 - or findings on physical examination consistent with spinal cord compression then he/she should be treated … within 24 hours or a contraindication for such therapy should be documented If a cancer patient is treated … Research Report Number 24 If an outpatient with cancer not receiving chemotherapy or radiation is treated … should be an assessment for the presence or absence of anorexia or dysphagia If a cancer patient is treated … same outpatient site of whether or not there was an improvement in anorexia If a cancer patient is treated

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