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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-radiation_technical-brief.pdf
    November 01, 2009 - studies of any design describing clinical outcomes or adverse events with 10 or more cancer patients treated … We also recorded the center/facility of particle beam treatment and the number of patients who were treated … “Prior treatments” were the initial failed interventions in patients who were treated for relapse. … Treated cancer categories were mainly limited to malignant tumors in the head, neck and spine, ocular … Base of skull and cervical spine chordomas in children treated by high-dose irradiation.
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer-update_executive.pdf
    December 01, 2014 - CER No. 20 that the risk of grade 2 or higher late xerostomia is significantly lower in patients treated … with IMRT compared with 41 percent of those treated with 3DCRT (p=0.11). … that late xerostomia was reduced and QOL domains related to xerostomia were improved in patients treated … Quality-of-life (QOL) outcomes in patients with head and neck squamous cell carcinoma (HNSCC) treated … Toxicity, quality of life, and functional outcomes of 176 hypopharyngeal cancer patients treated by
  3. effectivehealthcare.ahrq.gov/sites/default/files/covariate-selection-chapter-7.pptx
    January 01, 2013 - An “as treated” analysis allows subjects to switch treatment groups based on their use of treatment. … Both the “as treated” and “per protocol’’ analyses can be used to evaluate time-varying treatment. … increase in the confounder should, on average, always affect treatment in the same direction for both treated … treatment in the same direction and should always affect the outcome in the same direction for both the treated … If an increase in the confounder increased the outcome for the treated group and decreased the outcome
  4. effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
    September 21, 2012 - In the aspirin-treated subjects, there was a reduction in mortality (804 deaths among 8,587 people, … 9.4%) relative to subjects not treated with aspirin (1,016 deaths among 8,600 people, 11.8%, p<0.05 … astrological sign Gemini or Libra, there were more deaths (150 of 1,357, 11.1%) among the aspirin-treated … patients than there were among the non–aspirin- treated patients (147 of 1,442, 10.2%) (p not significant
  5. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive.pdf
    October 01, 2006 - Among patients treated with medical therapy alone, there is the risk of deterioration of kidney function … There is acceptable evidence that overall there is no difference in kidney outcomes between patients treated … The cohort studies generally found better blood pressure control among patients treated medically alone … However, 2 studies found larger reductions in blood pressure among patients treated without revascularization
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-200-post-acs-depression.pdf
    November 01, 2017 - In such strategies, patients are treated by a team that usually includes a primary care clinician, … care versus usual care • Evidence did not show increased adverse events among post-ACS individuals treated
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0094_04-09-2009.pdf
    January 01, 2009 - Effective Health Care Topic Number(s): 0051 Document Completion Date: 6-12-09 1 Results of Topic Selection Process & Next Steps  Therapies for autism spectrum disorders will go forward for refinement as a comparative effectiveness or effectiveness review. The scope of this topic, including pop…
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0277_03-10-2008.pdf
    January 01, 2008 - Effective Health Care Topic Number(s): 0059 Document Completion Date: 6-2-09 1 Results of Topic Selection Process & Next Steps  Bone marrow transplants (BMT) in children will go forward for refinement as a comparative effectiveness or effectiveness review. The scope of this topic, including po…
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/glucocorticoid-injections_clinician.pdf
    June 01, 2016 - Symptoms of LSS are commonly treated with epidural glucocorticoid injections.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/trauma-child-interventions_research-protocol.pdf
    March 26, 2012 - Evidence-based Practice Center Systematic Review Protocol Source: www.effectivehealthcare.ahrq.gov Published Online: March 26, 2012 Evidence-based Practice Center Systematic Review Protocol Project Title: Interventions Addressing Children Exposed to Trauma: Part 2 – Trauma Other Than Child Maltreatment an…
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
    March 01, 2013 - interpretation of a NNT of 10 over 3 years could be that “On average, 10 patients would have to be treated … For example, a NNT of 100 could be presented as 10 in 1,000 treated people will benefit from treatment
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
    February 01, 2012 - Patients who have been treated with novel therapies (exposed) and standard of care (non- exposed) … Patients who have been treated and developed late effects (cases) or did not develop late effects … Patients who have been treated and received a long-term care or survivorship plan (exposed) and … patients (n=10) compared with 0 percent for those treated with conventional therapy. … To determine prognostic variables in patients treated with these regimens.
  13. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive-2007.pdf
    January 01, 2007 - There is acceptable evidence that, overall, there is no difference in kidney outcomes between patients treated
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
    September 01, 2010 - 17.8 Children with Crohn’s disease are at risk for growth retardation in the absence of adequately treated … www.effectivehealthcare.ahrq.gov Published Online: September 01, 2010 AND (agent*[tiab] OR treatment*[tiab] OR treated … We will assume a normal likelihood and study effects (basic parameters) are treated as unrelated nuisance … Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_disposition-comments.pdf
    November 27, 2012 - clear and logical association between testing, treatment, and clinical outcomes: patients can’t be treated … eligibility have expanded over time, in part due to more effective therapies, and now patients may be treated … been studied with alfa-2a,3 although this study was conducted in patients who have been previously treated … Thus, patients with CKD Stages 3 to 5 may be treated with PEG-IFN or IFN monotherapy. … clear and logical association between testing, treatment, and clinical outcomes: patients can’t be treated
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-databases-methods_research.pdf
    May 01, 2008 - However, LTC residents are more likely to be treated with atypical antipsychotics (risperidone, olanzapine … received medical attention over the course of the year and might have overestimated the percent that were treated … In LTC settings, residents covered by Medicaid were approximately half as likely to be treated with … beneficiaries with dementia who are black or other race are significantly less likely than whites to be treated
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research-2012.pdf
    January 01, 2012 - NNT and NNH refer to the number of individuals that need to be treated over a specified period of time … risk reduction implies that 32 ischemic strokes will be prevented each year for every 1,000 patients treated … the results of the benefit harm assessment as the net number of events prevented per 10,000 women treated … For example, aspirin may prevent 10 major strokes in 1,000 middle-aged men treated for 10 years, as … Needed To Treat and Number Needed To Harm NNT and the NNH are the number of individuals who need to be treated
  18. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - Treatment of Opioid Overdose by Nonclinicians Unmet need: Opioid overdoses can be fatal when not treated
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
    November 19, 2009 - Modeling to evaluate benefits and harms of new diagnostic tests compared to established diagnostic tests – uses and limitations Medical Tests—White Paper Series Decision-Analytic Modeling to Evaluate Benefits and Harms of Medical Tests— Uses and Limitations The findings and conclusions in thi…
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
    June 01, 2013 - to question this assumption.9 For example, among a group of 128 patients with stage I or II NSCLC treated … persistent thoracic symptoms such as hemoptysis, cough, dyspnea, and postobstructive pneumonitis who were treated … A disproportionate number of patients 15 had received previous treatment in the laser-treated group … Retrospective study of 81 patients treated with brachytherapy for endobronchial primary tumor or metastasis

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