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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research-2012.pdf
    January 01, 2012 - Simpler approaches, such as the ratio of the number needed to treat to the number needed to harm, may … Number Needed To Treat and Number Needed To Harm The number needed to treat (NNT) and its harm counterpart … The number needed to treat: a clinically useful measure of treatment effect. … Number needed to treat (NNT): implication in rheumatology clinical practice. … Cancer Treat Rev. 1993; 19 Suppl A:73-84. 58. Gelber RD, Goldhirsch A, Cole BF, et al.
  2. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat … Several experts thought many clinicians and patients would welcome another drug approved to treat IBS … While there is only said to be one medication approved by the FDA to treat irritable bowel syndrome … Perfect,” and that “Patients would love it - an oral pill to treat irritable bowel syndrome that works … FDA approves two therapies to treat IBS-D. [internet]. Silver Spring (MD): U.S.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
    June 01, 2018 - the benefits and harms for antipsychotics compared to each other, placebo, or non-drug approaches to treat … benefits and harms for antipsychotics compared to each other, placebo, or non-drug approaches to treat … the benefits and harms for antipsychotics compared to each other, placebo, or non-drug approaches to treat … the benefits and harms for antipsychotics compared to each other, placebo, or non-drug approaches to treat … the benefits and harms for antipsychotics compared to each other, placebo, or non-drug approaches to treat
  4. effectivehealthcare.ahrq.gov/sites/default/files/infectiousdisease_hi_impact.pdf
    December 01, 2013 - Overall High Impact Potential: Fecal transplantation to treat recurrent C. difficile infection .... … *Fecal microbiota transplantation to treat recurrent C. difficile infection 6. …  Key Expert Comments: Overall, experts commented that a collaborative care model to treat MDD … Chronic relapsing CDIs are increasingly common and are challenging to treat effectively; about 20% … HS283 - Fecal transplantation to treat recurrent C.
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
    November 03, 2011 - We will use correction coefficients and intention to treat as recommended calculations for missing … and control groups. 53, 59 We will calculate means and 95 percent CIs for the number needed to treat … FDA News Release: FDA approves Botox to treat chronic migraine. … The use of numbers needed to treat derived from systematic reviews and meta- analysis. … Confidence intervals for the number needed to treat. BMJ. 1998 Nov 7;317(7168):1309-12.
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
    January 01, 2022 - plant-based compounds with effects similar to opioids or cannabis, such as kratom, have been considered to treat … drive a search for alternative pain treatments, including cannabis and related compounds to better treat … evidence on benefits and harms of cannabinoids and similar plant-based substances (e.g., kratom) to treat … Only short-term evidence is available for cannabis-related interventions containing THC and/or CBD to treat … small to moderate improvements in pain, and the complete adverse event profile of cannabinoids used to treat
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-2.xlsx
    January 01, 2021 - Intention-To-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences
  8. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
    April 01, 2012 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat … Food and Drug Administration (FDA) in April 2010 to treat adults (aged 18 years and older) with severe … the entire lung. 5 BT is intended to treat patients with no other treatment options and might reduce … The experts were split regarding their certainty of the underlying concept of BT to effectively treat … One expert with a health systems perspective stated that since BT will be used to treat only a subset
  9. effectivehealthcare.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
    December 01, 2020 - Finally, patients are often advised to use combinations of therapies to treat migraine attacks. … Rates and Predictors of Using Opioids in the Emergency Department to Treat Migraine in Adolescents … Rates and Predictors of Using Opioids in the Emergency Department to Treat Migraine in Adolescents
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-urinary-retention_disposition-comments.pdf
    September 15, 2014 - We intended to include any intervention type used specifically to treat CUR. … For these patients we are not looking to treat CUR, but rather induce and manage it. … , but maybe even more importantly, who to treat. … Basic questions of if and when to treat are not answered. … Questions of if and when to treat are important and answers to those questions may have priority over
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_policymaker.pdf
    June 01, 2016 - Steroids used to treat IH mainly include oral steroids and intralesional steroids (e.g., triamcinolone … The most common type of lasers used to treat IH are pulse dye lasers.
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
    March 10, 2010 - Methods Comment: CER focus on LDL-C does not adequately address role of combination therapy to treat … Revised A trial was considered to have employed intention-to-treat analysis when data were reported … (Ref 33) Kastelein was penalized because "Double-blind, and intention-to-treat Feldman … (Ref 35) Davidson was penalized because "no intention-to-treat analysis was described". … That is, for the endpoint analysis, data would be carried forward to endpoint in the Intent-to-Treat
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-liver-metastases-therapies_research-protocol.pdf
    September 27, 2012 - Current Treatments Several liver-directed therapies have been developed to treat patients with CRC … Patients who are candidates for liver-directed therapies with concomitant systemic chemotherapy to treat … In addition, intention-to-treat analysis is used for RCTs. o Fair. … Intention-to-treat analysis has been done for RCTs. o Poor. … Cancer Treat Rev 2011;In Press, Corrected Proof. PMID: 21726960 19.
  14. Slide 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/johnson_-ahrq-mcda-presentation.pdf
    August 27, 2012 - Treat with over - the - counter medicines Frequent moderate symptoms. … Treat with a prescription medicine RISK OF BLEEDING ULCER 1 patient out of 100 (1
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
    December 01, 2017 - Analysis of results for the intention-to-treat population did not find improvement, but analysis of … Compared with sham treatment, the intention-to-treat analysis in a single RCT suggests that BT had no
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-3.xlsx
    January 01, 2021 - Intention-To-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences
  17. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/should-subclinical-hypothroidism-be-treated
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_clinician.pdf
    August 01, 2016 - medications—including anticonvulsants, antipsychotics, mood stabilizers, and stimulants—have been used to treat … Some medications used to treat DBDs have not been approved by the U.S.
  19. effectivehealthcare.ahrq.gov/sites/default/files/cer-243-prehospital-airway-management-appendix-f-1_0.xlsx
    January 01, 2016 - probability of treatment weighting IQR interquartile range ISS Injury Severity Scale ITT intent to treat
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-fatigue_research-protocol.pdf
    May 01, 2014 - Administration (FDA) approved medications for the treatment of ME/CFS, but many have been used to treat … patient-focused drug development initiative, treatments fell into two broad categories, those intended to treat … Interventions targeting symptoms included medications to treat pain, fatigue, and sleep dysfunction, … 5040) 13 exp cognitive behavior therapy/ (15929) 14 (cognit$ adj3 behav$ adj5 (therap$ or treat … dt.fs. (1752044) 22 19 or 20 or 21 (2743222) 23 ((drug$ or pharmac$) adj3 (therap$ or treat

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