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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_executive.pdf
    April 01, 2012 - For Key Questions 2 and 3, we calculated relative risk, absolute risk differences, number needed to treat … The numbers needed to treat (NNT) to achieve continence in one woman were similar across drugs. … studies were double blind with adequate randomization and clear reporting of planned intention-to- treat … The quality of the studies, including intention-to-treat analysis and adequacy of allocation concealment … Glossary AHRQ Agency for Healthcare Research and Quality CI Confidence interval NNT Number needed to treat
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/delirium-disposition-comments.pdf
    September 03, 2019 - Given this attention, this report on antipsychotics to prevent and treat delirium is timely and meaningful … include a psychiatrist although they are frequently consulted for patients experiencing delirium and treat … Unfortunately, much of the research has misguidedly focused on trying to prevent and treat the manifestations … although antipsychotics may or may not prevent delirium in some patients, they definitely do not “treat … in other study samples that have been used to test the efficacy of antipsychotics to prevent and treat
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-future_research.pdf
    March 01, 2012 - angiotensin II receptor blocker(s)/antagonist(s); DRI(s) = direct renin inhibitor(s); ITT = intention-to-treat
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0398_06-17-2008.pdf
    January 01, 2008 - Effective Health Care Topic Number: 0174 Document Completion Date: 7-28-10 1 Results of Topic Selection Process & Next Steps  Biomarkers to guide treatment for iron-deficiency anemia in renal dialysis patients will go forward for refinement as a systematic review. The scope of this topic, incl…
  5. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
    January 01, 2012 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat … and top-dose as compared to -1.8% for the placebo group (lease-squares mean ITT-LOCF [intention to treat–last
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
    April 01, 2013 - We used default software continuity coefficients for 0 events and intention to treat as recommended … We calculated means and 95% CIs for the number needed to treat as reciprocal to pooled ARD when the … Planned intention to treat was reported in 24 percent of RCTs. … Clinicians need to treat three to five patients with episodic migraine to prevent half or more migraine … FDA News Release: FDA Approves Botox to Treat Chronic Migraine. 2010. www.fda.gov/ NewsEvents/Newsroom
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_disposition-comments.pdf
    June 05, 2013 - Short-term outcomes: There is moderate strength of evidence that bariatric surgery is an effective way to treat … intermediate outcome in terms of being on the pathway to improvement in comorbid conditions, however we treat … In sum, there is moderate strength evidence that bariatric surgery is an effective way to treat diabetes … outcomes: In sum, there is moderate strength evidence that bariatric surgery is an effective way to treat … However challenging though, efforts must be made to both prevent and treat obesity at all stages and
  8. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
    January 01, 2012 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-224-depression-children-comments.pdf
    April 10, 2020 - measures are used that indicate the number needed to harm (NNH) and number needed to treat. … We have added a table for numbers needed to treat and harm, and we hope that this table will help focus … examples include: • Line 15 in the Introduction to the Evidence Summary (“…treatment options to treat … examples include: • Line 15 in the Introduction to the Evidence Summary (“…treatment options to treat … J Subst Abuse Treat. 2012 Jun;42(4):366-72. doi: 10.1016/j.jsat.2011.09.010. PMID: 22116008. 7.
  10. Gout Executive (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive.pdf
    March 01, 2016 - Table A lists the drugs used to treat gout and notes the ones covered in this systematic review. … We contacted manufacturers of the prescription medications used to treat gout that are listed in Table … populations to those for which this report is intended, namely primary and acute care settings that treat … Research Gaps The concept of “treat-to-target” (TTT) in gout, while supported by indirect evidence,
  11. effectivehealthcare.ahrq.gov/sites/default/files/adhd_executive.pdf
    October 01, 2011 - Attention Deficit Hyperactivity Disorder: Executive Summary                                                                                                                                                                                                                                                       …
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/glucocorticoid-injections_clinician.pdf
    June 01, 2016 - include a sham injection; thus, the effects of lumbar glucocorticoid injections in comparison with no treat
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause-protocol-130612.pdf
    June 12, 2013 - concluded, “Recent data support the initiation of [hormone therapy] around the time of menopause to treat … menopause-related symptoms; to treat or reduce the risk of certain disorders, such as osteoporosis … Question 3—Nonhormone Other Benefits/Harms We will limit our review to studies using the drugs to treat … Intention to treat analysis is performed. … Intention to treat analysis is lacking.
  14. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat … of buccal insulin has the potential to be offset by improved treatment outcomes and less need to treat … policies online has a policy that describes coverage for ranibizumab 0.3 mg intravitreal injection to treat … intervention’s potential for clinician and patient acceptance is high because more effective therapy to treat … FDA approves Lucentis to treat diabetic macular edema. [internet]. Silver Spring (MD): U.S.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-interventions-future_research.pdf
    September 01, 2012 - Interventions that warrant rigorous evaluation include: those intended to treat behavioral issues, … Interventions that warrant rigorous evaluation include those intended to treat behavioral issues, including
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/living-systematic-reviews-full-text-articles-white-paper.pdf
    January 01, 2024 - Background Chronic pain is difficult to treat successfully. … Curr Treat Options Gastroenterol. 2005;8(6):433-41. doi: 10.1007/s11938-005-0029-5. … Curr Treat Options Gastroenterol. 2005;8(6):433-41. doi: 10.1007/s11938-005-0029-5.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
    May 19, 2010 - Intent- to-treat results will be recorded if available. … proportion of subjects lost to follow-up and important differences between treatments; use of intent-to-treat … They are used to treat psychiatric conditions and have varying mechanisms of action.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
    February 01, 2012 - Resource Use, Size and Duration Likely to require substantial resources to recruit and treat the … way to approach the question. 25 Discussion In the pediatric population, HSCT is used to treat … (SLE); Nanjing Medical University, Jiangsu, China , NCT00698191 To explore a new approach to treat … To explore safety and efficacy of allogeneic mesenchymal stem cells transplantation (MSCT) to treat
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/erythropoiesis-stimulating-agents-utilization_research.pdf
    February 01, 2011 - Thereby, modalities became available for the treat- ment of anemia in chronic renal failure, chemotherapy-treated
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
    September 01, 2010 - hospitalizations and surgeries, while improving quality of life and the ability to work.9 Interventions to treat … cured with wide surgical resection; this is now known to be untrue.10,11 Medications are now used to treat … www.effectivehealthcare.ahrq.gov Published Online: September 01, 2010 middle of the last century to treat … For our study of medications to treat moderate to severe Crohn’s disease, we will include randomized

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