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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol.pdf
    November 03, 2014 - visits for acute flares, and 61 percent were attributed to expenditures for prescription medications to treat … Commonly advocated agents to treat acute gout include non-steroidal anti- inflammatories (NSAIDS), colchicine … Table 1 lists the drugs used to treat gout and notes the ones covered in this systematic review. … populations to those for which this report is intended, namely primary and acute care settings that treat
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
    July 13, 2011 - Evidence Report on the Source: www.effectivehealthcare.ahrq.gov Published Online: July 13, 2011 Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of Second Generation Antidepressants in the Pharmacologic Treatment of Adult Depression – An Update to a 20…
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-future_research.pdf
    October 26, 2012 - severe CDI; Improved clinical cure based on per-protocol analysis, but not with strict intention-to-treat … Treating CDI, placebo: Administration of a probiotic with live bacteria to treat CDI in critically ill … severe CDI; Improved clinical cure based on per-protocol analysis, but not with strict intention-to-treat … Treating CDI, placebo: Administration of a probiotic with live bacteria to treat CDI in critically ill … Treating CDI, placebo Low Administration of a probiotic with live bacteria to treat CDI in critically
  4. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat … One of these, thalidomide, has been investigated in a phase III trial for off-label use to treat cough … care processes and patient management by offering patients a convenient oral therapy to directly treat … care processes and patient management by offering patients a convenient oral therapy to directly treat … FDA approves KALYDECO to treat rare form of cystic fibrosis. [internet].
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/bereaved-persons-protocol.pdf
    June 01, 2023 - Interventions to treat prolonged grief disorder include interpersonal psychotherapy, cognitive behavioral … Most studies on interventions to treat bereaved individuals, however, are small pilot studies.29 There … consequences (e.g., prolonging the grief) KQ3 Interventions Interventions to prevent or treat … KQ2: Diagnostic strategy evaluation, diagnostic or screening tool KQ3: Interventions to prevent or treat … early termination of studies, inadequate reporting of intervention details, and lack of intention-to-treat
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nomination-apbi-breast-cancer.pdf
    April 01, 2017 - Technol Cancer Res Treat. 2011;10(4):323-329. 28. Maluta S, Dall'Oglio S, Goer DA, Marciai N. … Breast Cancer Res Treat. 2012;135(1):253-260. 31. Chang DW, te Marvelde L, Chua BH. … Breast Cancer Res Treat. 2013;140(1):119-133. 40. Lewin AA, Derhagopian R, Saigal K, et al.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0012_03-21-2008.pdf
    January 01, 2008 - Effective Health Care Topic Number(s): 0064 Document Completion Date: 11-18-09 1 Results of Topic Selection Process & Next Steps  Subclinical hypothyroidism will go forward for refinement as a comparative effectiveness or effectiveness review. Although the topic was initially thought to be cove…
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/menopause_research-protocol.pdf
    March 25, 2012 - concluded, “Recent data support the initiation of [hormone therapy] around the time of menopause to treat … menopause-related symptoms; to treat or reduce the risk of certain disorders, such as osteoporosis … Question 3—Nonhormone Other Benefits/Harms We will limit our review to studies using the drugs to treat … Intention to treat analysis is performed. … Intention to treat analysis is lacking.
  9. Topic-Brief3-Sud (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief3-SUD.pdf
    April 01, 2021 - pain tolerance, higher analgesic requirements, the addiction potential of some medications used to treat … of other psychiatric conditions.4-9 In addition, the use of partial or full opioid antagonists to treat … J Subst Abuse Treat. 2017 Jun;77:26-30. doi: 10.1016/j.jsat.2017.03.006. PMID: 28476267. 3. … information about multimodal pain care options in outpatient and inpatient settings to effectively treat
  10. Topic-Brief3-Sud (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief3-SUD.pdf
    April 01, 2021 - pain tolerance, higher analgesic requirements, the addiction potential of some medications used to treat … of other psychiatric conditions.4-9 In addition, the use of partial or full opioid antagonists to treat … J Subst Abuse Treat. 2017 Jun;77:26-30. doi: 10.1016/j.jsat.2017.03.006. PMID: 28476267. 3. … information about multimodal pain care options in outpatient and inpatient settings to effectively treat
  11. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1312.pdf
    January 01, 2016 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat … have undergone bariatric surgery has generated interest in the potential of bariatric surgery to treat … intraocular pressure might dissuade physicians from embracing fluocinolone acetonide implants to treat … The implant is expected to compete with VEGF inhibitors, such as ranibizumab, also approved to treat … FDA approves Lucentis to treat diabetic macular edema. [internet]. Silver Spring (MD): U.S.
  12. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label_executive.pdf
    January 01, 2007 - Remaining Issues More research about how to safely treat agitation in dementia is urgently needed.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
    February 10, 2016 - www.effectivehealthcare.ahrq.gov Published online: November 9, 2015 2     Many  practitioners  treat …  outcome[tiab]  OR   outcomes[tiab]  OR  treatment[tiab]  OR  treatments[tiab]  OR  treatment*  OR  treat … Appendix  A   outlines  manufacturers  of  key  device  and  drugs  used  to  treat  the  population   … Leukotriene  inhibitors:  These  drugs  are  FDA-­approved  to  treat  asthma  symptoms  in  children …  surgical   devices  include  a  variety  of  devices  for  surgical  procedures  to  examine  or  treat
  14. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
    February 01, 2008 - Layout 1 Background and Key Questions Prostate cancer is the most common nondermatologic cancer in men. In 2007 an estimated 218,890 men were diagnosed with, and 27,050 deaths were attributed to, prostate cancer in the United States. Approximately 90 percent of men with prostate cancer have disease considered confine…
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0351_05-10-2010.pdf
    January 01, 2010 - Effective Health Care Topic Number(s): 0265 Document Completion Date: 09-13-10 1 Results of Topic Selection Process & Next Steps  Cryptorchidism (undescended testicle) will go forward for refinement as a systematic review. The scope of this topic, including populations, interventions, compara…
  16. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat … readily available illicit opioid drugs, such as heroin, and increased use of prescription opioids to treat … delivers a single 0.4 mg naloxone dose, equal to a typical dose administered by medical professionals to treat
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pwd-care-interventions-protocol.pdf
    February 22, 2019 - Although drug and nondrug interventions are available to treat symptoms, support function, and improve … (Drugs and over-the-counter supplements to treat clinical Alzheimer’s-type dementia and behavioral and … Any nondrug care intervention intended to benefit PWD except interventions to treat conditions other … care intervention intended to support informal PWD caregivers’ well-being except interventions to treat … The American Psychiatric Association Practice Guideline on the Use of Antipsychotics to Treat Agitation
  18. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1412.pdf
    January 01, 2015 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat … have undergone bariatric surgery has generated interest in the potential of bariatric surgery to treat … intraocular pressure might dissuade physicians from embracing fluocinolone acetonide implants to treat … and development of secondary complications, and eliminates the attendant health services needed to treat … priced comparably to Retisert®, a fluocinolone acetonide ophthalmic implant that is FDA-approved to treat
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
    May 01, 2015 - 1 Treatments for Ankyloglossia and Ankyloglossia With Concomitant Lip-Tie Executive Summary Introduction Ankyloglossia is a congenital condition characterized by an abnormally short, thickened, or tight lingual frenulum, or an anterior attachment of the lingual frenulum, that restricts mobility of the tongue.1…
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_disposition-comments.pdf
    November 27, 2012 - Reviewer #1 General This report leaves the clinician with little direction as to how to better treat … We specifically separated metoclopramide from the neuroleptics since clinicians appear to treat these … At one point I was using promethazine (Phenergan) to treat all my ED migraine patients. … Peer Reviewer #9 Clarity and usability Opioids are often used to treat acute migraine despite their … We have changed the wording as follows: “Opioids are often used to treat acute migraine despite their

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