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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
    November 01, 2014 - The general approach is to treat broadly for resistant Gram-positive and Gram- negative organisms, then … Some patients may require intubation after developing severe HAP; in these cases, clinicians should treat … Table A lists antibiotic classes and individual agents that clinicians might use to treat HAP; bold … allocation concealment, similarity of groups at baseline, masking, attrition, whether intention-to-treat … more rapidly and accurately, public policies to support development and approval of new drugs to treat
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_executive.pdf
    February 01, 2012 - 1 Comparative Effectiveness Review Number 56 Adjuvant Treatment for Phenylketonuria (PKU) Executive Summary Background Etiology Phenylketonuria (PKU) is a metabolic disorder in which an inability to properly metabolize the amino acid phenylalanine (Phe) leads to a buildup of Phe in the blood, causing neurot…
  3. #05 DEPRESSION (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat … Accordingly, researchers are investigating various anticholinergic drugs as antidepressants to treat … is paramount.2 An unmet need exists for fast-acting, well-tolerated antidepressants to effectively treat … Racemic ketamine is usually intravenously or intramuscularly injected at subanesthetic doses to treat … Anticonvulsants, antipsychotics, benzodiazepine, and lithium are frequently prescribed to treat BPD
  4. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat … FDA approves Orkambi (lumacaftor/ivacaftor) - the first medicine to treat the underlying cause of … FDA approves Nucala to treat severe asthma. [internet]. Silver Spring (MD): U.S. … FDA approves Ofev to treat idiopathic pulmonary fibrosis. [internet]. Silver Spring (MD): U.S. … FDA approves Esbriet to treat idiopathic pulmonary fibrosis. [internet].
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse_executive.pdf
    April 28, 2010 - Low CI = confidence interval; N = number; RCT = randomized controlled trial; TrEAT = Trial for Early … cThese data are from Project TrEAT;43-45 the best available evidence. … The brief multicontact intervention used in Project TrEAT (which provides some of the best evidence … J Subst Abuse Treat. 2000 Jun; 18(4):365-9. PMID: 10812310. 80. … J Subst Abuse Treat. 2006 Dec; 31(4):419-24. PMID: 17084796. 84.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mat-retention-strategies-rapid-review-1.pdf
    August 01, 2020 - J Subst Abuse Treat. 2018;85:45-8. doi: https://dx.doi.org/10.1016/ j.jsat.2017.04.010. … J Subst Abuse Treat. 2019;97:68-74. doi: https://dx.doi.org/10.1016/j.jsat.2018. … J Subst Abuse Treat. 2018;85:45-8. doi: https://dx.doi.org/10.1016/j.jsat.2017.04.010 . … J Subst Abuse Treat. 2014;46(1):43-51. doi: https://dx.doi.org/10.1016/j.jsat.2013.08.012 . … J Subst Abuse Treat. 2019;97:68-74. doi: https://dx.doi.org/10.1016/j.jsat.2018.
  7. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
    January 01, 2007 - glomerular filtration rate; LV = left ventricular; MI = myocardial infarction; NNT = number needed to treat
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_clinician.pdf
    July 01, 2016 - Surgical procedures used to treat fecal incontinence in the United States include implanted sacral nerve
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-3-noninvasive-nonpharma.xlsx
    January 01, 2022 - chronic pain report Author, Year Condition Random-ization Concealed Treatment Allocation Intention to Treat
  10. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat … Liraglutide, which is already on the market for treating diabetes and is being used off-label to treat … Liraglutide is already approved to treat T2DM, and, given the paucity of effective obesity treatments … T2DM, exenatide (Byetta®), are already being used off-label to treat obesity. … FDA approves Belviq to treat some overweight or obese adults. [internet].
  11. effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat … Lesinurad could be used in combination with xanthine oxidase inhibitors to treat hyperuricemia.
  12. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1306.pdf
    July 01, 2013 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat … The cost of liraglutide at the dosage used to treat obesity is expected to be greater than the cost … Liraglutide is already approved to treat T2DM, and given the paucity of effective obesity treatments … A research expert stated that there is “already prevalent off-label use of this drug to treat obesity … FDA approves Belviq to treat some overweight or obese adults. [internet].
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
    July 01, 2014 - Antidepressant medications are used to treat a variety of other indications, including anxiety disorders … A wide array of nonpharmacological interventions can be used to treat depression, including various … In babies born to women who become pregnant while taking medications to treat depression, what is the … Intention-to-treat results were recorded if available. … had no direct evidence for the risk of infant mortality with maternal use of antidepressant drugs to treat
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
    June 16, 2010 - in the United States)—have been extensively studied and used clinically for more than a decade to treat … Therefore, comparisons of ESAs and transfusions to treat anemia to different Hb levels are not valid … “intention-to-treat” and “as treated” analyses, we will use the intention-to-treat based data for a … Did the analysis include an intention-to-treat analysis? … If the relative effect is independent of baseline risk (control rate), numbers needed to treat (NNT)
  15. S38 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s38.pdf
    October 01, 2007 - eligibility criteria would strengthen the trial; what covariates are likely to influence adherence to treat … In a placebo-controlled trial, nonadherence biases esti- mated treatment effects in an intention to treat … not comply and a proportion p2 of individuals assigned to placebo independently initiate the active treat … Once such people are randomized, they must be included in intention to treat analyses. … treatment assignment where at the time of each randomization the distribution of covariates between treat
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/recombinant-factor-viia_clinician.pdf
    October 01, 2010 - Thromboembolic events are increased by use of rFVIIa to treat spontaneous intracranial hemorrhage
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0371_11-23-2010.pdf
    January 01, 2010 - could be measured using patient-centered outcomes), intervention-related changes in how clinicians treat
  18. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-2005_executive.pdf
    January 01, 2005 - Layout 1 Background Gastroesophageal reflux disease (GERD), defined as weekly heartburn and/or acid regurgitation, is one of the most common health conditions affecting older Americans. Direct costs attributable to GERD were estimated to be $10 billion in the United States in 2000. Some patients have frequent, sever…
  19. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat … care processes and patient management by offering patients a convenient oral therapy to directly treat … Patients with CF often require chronic use of inhaled, intravenous, or oral antibiotics to prevent or treat … care processes and patient management by offering patients a convenient oral therapy to directly treat … FDA approves KALYDECO to treat rare form of cystic fibrosis. [internet].
  20. effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - new and evolving health care interventions that are purported to or may hold potential to diagnose, treat … and delivered by any suitably equipped health care center, and dozens of orthopedic centers that treat … Unmet need and health outcomes: Current OA therapies treat only the symptoms and do not restore cartilage … already be demand for the procedure, even though MSC injection is similar to other injections used to treat … Unmet need and health outcomes: Current therapies for OA treat only the symptoms and do not restore

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