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www.uspreventiveservicestaskforce.org/home/getfilebytoken/vmHooQ6ABG9CagdUXv2_rx
August 25, 2021 - Treatment interventions to lower lipid levels generally include life-
style modification (eg, changes … • The USPSTF found adequate evidence that the harms of treatment of familial hypercholesterolemia or … USPSTF reviewed 22 fair- to good-quality trials (n = 2257)
examining the effectiveness of lipid-lowering treatments … good-quality trials (n = 1008) examining the
effectiveness of various nonpharmacologic lipid-lowering
treatments … • Long-term data on the harms of screening and treatment.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/CXDusYW7s2xdypXMpnW9sw
June 20, 2023 - What are the harms of treatment of anxiety risk (psycho-
therapy or pharmacotherapy) in adults, including … In contrast, a substantial evi-
dence base indicated that effective treatments are available to
treat … Mindfulness-based cognitive therapy intervention
for the treatment of late-life depression and anxiety … How effective are cognitive behavior
therapies for major depression and anxiety
disorders? … The effects of cognitive and behavioural
therapies for anxiety disorders on depression:
a meta-analysis
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/genital-herpes-screening-2005
March 15, 2005 - Potential harms of antiviral treatment may include drug hypersensitivity and renal impairment; however … , antiviral treatments are generally well tolerated with mild harms. 11-13 There is limited evidence … on the safety of antiviral treatments during pregnancy. 25 , 26
A cost analysis of oral acyclovir … The Centers for Disease Control and Prevention HSV treatment recommendations can be accessed at: https … Sexually transmitted diseases treatment guidelines 2002.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/oPmYxryXGu2occANaReagc
August 01, 2022 - persons in the isoniazid-only group, and combination therapy was
found to be noninferior. … isoniazid and 1.1% for rifampin.131
Meta-analysis found no statistically significant difference between
treatments … It is unclear whether
changes in the prevalence of tuberculosis (which has decreased),
treatments for … noninferiority, improved adherence, and lower risk of hepa-
totoxicity for current, CDC-preferred LTBI treatments … Adverse
events with 4 months of rifampin therapy or 9
months of isoniazid therapy for latent tuberculosis
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan34/sexually-transmitted-infections-behavioral-counseling-september-2014
May 15, 2013 - Biomedical HIV/STI prevention interventions (e.g., prophylactic vaccinations, antiretroviral therapy … Correctional facilities
School classrooms
Worksites
Substance abuse treatment … Sexually transmitted diseases treatment guidelines, 2010.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/healthy-weight-and-weight-gain-during-pregnancy-behavioral-counseling-interventions
July 26, 2018 - programs (e.g., mass media, changes to the community-built environment)
Comparisons
No treatment
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-aspirin-to-prevent-cardiovascular-diseas/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
October 07, 2013 - available cardiovascular risk prediction tools commonly used in practice are good candidates to guide therapeutic … nonoral, nontablet forms of aspirin; exposure of less than 12 months
Comparisons
Placebo or no treatment
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan109/preeclampsia-screening-april-2017
August 14, 2014 - What established protocols for preeclampsia management and treatment are known to reduce morbidity and
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6cRgd5whkAvSGESSQsrQLR
January 01, 2020 - Treatments and
Interventions
Asymptomatic adults at increased risk for CVD are usually treated with … Two RCTs (total N = 4626) compared using the ABI to guide
decisions to start aspirin therapy vs usual … the effect of screening with
CAC score on risk perception, adherence to medication, and behav-
ioral therapies … Some comments also expressed
belief that CAC score testing leads to better adherence to preven-
tive therapies … It recommends judicious use of secondary test-
ing among patients for whom the need for statin therapy
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/vision-in-children-ages-6-months-to-5-years-screening
September 05, 2017 - for identifying preschool children at higher risk for vision problems and the effectiveness of some treatments … each included study, 1 investigator extracted pertinent information about the populations, tests or treatments … ) and parent (worry about treatment, upset by treatments, arguments about treatment), it did not report … performance, functioning, or quality of life, and no eligible studies evaluated atropine or vision therapy … The therapy of amblyopia: an analysis of the results of amblyopia therapy utilizing the pooled data of
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-nonpregnant-adolescents-and-adults1/human-immunodeficiency-virus-hiv-infection-screening
June 11, 2019 - Treatment Initiation at Higher vs Lower CD4 Cell Count
Key Question 4. … Longer-Term Harms of Treatment
Key Question 5. … Initiation of antiretroviral therapy at high CD4+ cell counts is associated with positive treatment outcomes … Risk of cardiovascular events associated with current exposure to HIV antiretroviral therapies in a US … Optimal time for initiation of antiretroviral therapy in asymptomatic, HIV-infected, treatment-naive
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/problem-drinking-screening-1996
January 01, 1996 - substitution of nonalcoholic beer. 82 , 83
Pregnancy
There are no definitive controlled trials of treatments … the wide variety of interventions employed, and the absence of any rigorous evaluation of different treatments … treatments were effective, but there was no single superior treatment for all patients, and few treatments … of other life problems (e.g., with antidepressant medication, family or marital therapy, or stress management … Naltrexone and coping skills therapy for alcohol dependence: a controlled study.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/family-violence-screening-interventions-1996
January 01, 1996 - Such persons may be referred for psychiatric counseling or family therapy to learn stress management … Studies evaluating the effectiveness of treatments for abused children are limited, and their results … A randomized trial of group therapy (vs. standard care) for convicted wife-abusers showed that repeat … An outpatient treatment program for child molesters. … Battered women—their susceptibility to treatment.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary48/suicide-risk-screening-2004
May 15, 2004 - Dialectical behavior therapy (DBT), a comprehensive treatment program developed to treat severely dysfunctional … An asterisk at the word "treatment" on the KQ 2 arrow refers to a footnote: "Treatments were categorized … Limit 1 to (human and English language)
19,492
NA
3
Explode therapeutics … with behavior therapy for 10 days
Control: Inpatient psychiatric treatment with insight-oriented … Psychosocial versus pharmacological treatments for deliberate self harm.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/B73a4kJhxeaYyXK6gozbbY
May 24, 2022 - outcomes
Reporting bias not detected
Moderate for
benefit
VEGF inhibitors are considered first-line therapy … detected
Moderate for
no harm
VEGF inhibitors vs sham:
VEGF inhibitors are considered first-line therapy … Morphology and visual acuity in aflibercept and
ranibizumab therapy for neovascular age-related
macular … Oral zinc-therapy in age-related macular
degeneration: a double blind study. … Introducing
anti-vascular endothelial growth factor therapies
for AMD did not raise risk of myocardial
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ovXMtAPc8TCPQzVRkEYhyd
August 01, 2013 - Harms of Detection and Early Intervention or Treatment
Although there are numerous concerns about the … “Child mal-
treatment” is defined by the Centers for Disease Control
and Prevention as any act or series … Assessment of Risk
Numerous risk factors are associated with child mal-
treatment, including but not … Clinical report—the pediatrician’s role in child mal-
treatment prevention. … Child Abuse Prevention and Treatment Act Amendments of 1996, Pub. L.
No. 104-235.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/tobacco-use-intervention-prevention-cessation-children-adolescents
June 27, 2024 - Tobacco does not refer to nicotine replacement therapy. … Tobacco does not refer to nicotine replacement therapy. … prevent or reduce tobacco * use in children and adolescents
Complementary and alternative medicine treatments … Tobacco does not refer to nicotine replacement therapy. … that tobacco refers to both tobacco and nicotine products (with the exception of nicotine replacement therapy
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/efwy72cuMdhcF2jotkhTzC
March 29, 2019 - significantly following the implementation of
routine prenatal HIV screening and the use of effective therapies … significantly following the
implementation of routine prenatal HIV screening and the use of
effective therapies … Initiation
of antiretroviral therapy at high CD4+ cell counts
is associated with positive treatment outcomes … Risk of
cardiovascular events associated with current
exposure to HIV antiretroviral therapies in a US … highly active antiretroviral therapy during
pregnancy.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/screening-for-prediabetes-and-type-2-diabetes
August 24, 2021 - each included study, 1 investigator extracted pertinent information about the populations, tests or treatments … White participants from 1977 through 1997, when routine care for CVD prevention would not have included treatments … the trial began in 1986, when (like UKPDS) routine care for CVD prevention would not have included treatments … now considered to be current standard medical therapy. … Saxagliptin as initial therapy in treatment-naive Indian adults with type 2 diabetes mellitus inadequately
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/rQBBkz9CrHh4vp7ZnEkF-t
July 18, 2023 - or without an inherited component from
single-nucleotide variants with smaller additive effects.2-4
Therapies … For KQ4, RCTs of treatments for
dyslipidemia including drugs, behavioral counseling, and supple-
ments … Treatment Benefit
KQ4. … Twenty-two fair- to good-quality trials (n = 2257)
examined the effectiveness of various lipid-lowering treatments … No
treatment trials reported long-term health outcomes.
Treatment Harms
KQ5.