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www.uspreventiveservicestaskforce.org/home/getfilebytoken/vCzPVrVJfgFWfpWRdEHMKQ
July 01, 2012 - or androgen depri-
vation therapy (7, 8). … urinary incontinence
and erectile dysfunction in at least 200 to 300 of 1000 men
treated with these therapies … , radiation, hormonal therapy, or some combina-
tion). … Treatments for Localized Prostate Cancer: Systematic Review to Update the 2002
U.S. … Presented at the 53rd Annual Meeting of the American Society for
Therapeutic Radiology and Radiation
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-adults-screening-and-management-2012
June 15, 2012 - Benefits of Detection and Early Intervention/Treatment
The USPSTF found adequate evidence that intensive … Effectiveness of Detection and/or Treatment
No new trials were identified that compared screening for … Both also recommend that weight-loss and weight-maintenance therapies should include a reduced-calorie … diet, increased physical activity, and behavioral therapy. … Effectiveness of primary care--relevant treatments for obesity in adults: a systematic evidence review
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/statin-use-in-adults-preventive-medication
August 23, 2022 - Benefits of Statin Treatment
Key Question 1a. … group, high crossover from usual care, and increased use of nonstatin therapies in the usual care group … Harms of Statin Treatment
Key Question 2a. … by Treatment Intensity
Key Question 3. … of secondary prevention, defined statin intensity inadequately, or included nonstatin lipid-lowering therapies
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/breast-cancer-screening
April 30, 2024 - risk of breast cancer (eg, BRCA1 or BRCA2 genetic variation), a history of high-dose radiation therapy … In general, DCIS treatment, which may include surgery, radiation, and endocrine treatment, is intended … women. 27-36 Adjuvant endocrine therapy reduces the risk of cancer recurrence among individuals with … Black women are more likely to discontinue adjuvant endocrine therapy compared with White women, in part … Racial differences in patient-reported symptoms and adherence to adjuvant endocrine therapy among women
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cancer/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
April 11, 2016 - and secondary prevention trials, 20-year CRC mortality was reduced among persons assigned to aspirin therapy … Evidence from CVD primary and secondary prevention studies suggested that aspirin therapy reduces CRC … Effects of aspirin therapy on total cancer incidence within 10 years of initiation were generally small … Cuzick and colleagues used a modeling approach to conclude that the benefits of initiating therapy with … Evidence from primary and secondary prevention studies suggests that aspirin therapy reduces the risk
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/4y3P9DxovKMEjNmVd2mrPp
December 01, 2007 - and the inevitable failure to follow
through on the test or any subsequent steps needed before
the therapeutic … Volume 147 • Number 12 www.annals.org
stenosis in the general population, the generalizability of
treatment … Widespread screening for carotid ar-
tery stenosis would invariably lead to surgical treatment
provided … is unavailable, or when evidence about the ben-
efits of treatment is insufficient. … For
example, the benefits of prophylactic aspirin therapy
among men include fewer coronary heart events
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/oPmYxryXGu2occANaReagc
August 01, 2022 - persons in the isoniazid-only group, and combination therapy was
found to be noninferior. … isoniazid and 1.1% for rifampin.131
Meta-analysis found no statistically significant difference between
treatments … It is unclear whether
changes in the prevalence of tuberculosis (which has decreased),
treatments for … noninferiority, improved adherence, and lower risk of hepa-
totoxicity for current, CDC-preferred LTBI treatments … Adverse
events with 4 months of rifampin therapy or 9
months of isoniazid therapy for latent tuberculosis
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/R3y9LSud52CGL8mG4wvxoT
June 09, 2020 - In treatment-seeking populations,
opioid agonist therapy and naltrexone were associated with decreased … Retention in substance use
treatment was also an outcome for pharmacological therapy. … After 4 to 12 months
of treatment, opioid agonist therapy was associated with de-
creased risk of relapse … Pharmacological Therapies
Opioid Agonist Therapy (Buprenorphine or Methadone) | Four trials
of buprenorphine … Reinforcement-based therapy: 12-month evaluation
of an outpatient drug-free treatment for heroin
abusers
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/e9f8a_uGMXxSbBUxpRPkrc
June 18, 2024 - Two trials
of interpersonal therapy with limited counseling to change diet
and physical activity found … Since the prior review for the USPSTF, several new pharmaco-
therapy agents have been approved for use … Family-based treatment of severe pediatric obesity:
randomized, controlled trial. … Phentermine/topiramate for the treatment of
adolescent obesity. … Family-based obesity treatment, then
and now: twenty-five years of pediatric obesity
treatment.
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obesity-in-children-and-adolescents-screening-june-2017
June 20, 2017 - reflected in the unadjusted analyses. 68 , 69 , 71 The trial with the most intensive concomitant lifestyle therapy … Despite differences in metformin dose and concomitant therapy between trials, statistical heterogeneity … Metformin and placebo therapy both improve weight management and fasting insulin in obese insulin-resistant … center, treatment × center interaction, body weight <80 or ≥80 kg. … weight reduction with very low statistical heterogeneity, despite differences in dose and background therapy
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/problem-drinking-screening-1996
January 01, 1996 - substitution of nonalcoholic beer. 82 , 83
Pregnancy
There are no definitive controlled trials of treatments … the wide variety of interventions employed, and the absence of any rigorous evaluation of different treatments … treatments were effective, but there was no single superior treatment for all patients, and few treatments … of other life problems (e.g., with antidepressant medication, family or marital therapy, or stress management … Naltrexone and coping skills therapy for alcohol dependence: a controlled study.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/skin-cancer-screening
April 18, 2023 - Immunotherapy and targeted therapy are also used to treat advanced melanoma. … There are several treatments for keratinocyte carcinoma, including surgical excision, Mohs micrographic … surgery, radiation therapy, electrodessication and curettage, and photodynamic therapy, among others … harms vary in frequency and severity depending on treatment type. … Harms tend to be infrequent and less severe for local excisional treatments, whereas systemic treatments
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/B73a4kJhxeaYyXK6gozbbY
May 24, 2022 - outcomes
Reporting bias not detected
Moderate for
benefit
VEGF inhibitors are considered first-line therapy … detected
Moderate for
no harm
VEGF inhibitors vs sham:
VEGF inhibitors are considered first-line therapy … Morphology and visual acuity in aflibercept and
ranibizumab therapy for neovascular age-related
macular … Oral zinc-therapy in age-related macular
degeneration: a double blind study. … Introducing
anti-vascular endothelial growth factor therapies
for AMD did not raise risk of myocardial
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/zk8YxjaQxLGUTtt__nBQB_
September 09, 2021 - Efficacy of
self-guided internet-based cognitive behavioral
therapy in the treatment of depressive symptoms … Maternal, fetal, and child outcomes of mental
health treatments in women: a meta-analysis of
pharmacotherapy … Dialectical behavior therapy as a precursor to
PTSD treatment for suicidal and/or self-injuring
women … The effect
of a therapeutic smartphone application on suicidal
ideation in young adults: findings from … Adverse effects of pharmacologic treatments
of major depression in older adults.
-
www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/benefit.pdf
December 01, 2007 - and the inevitable failure to follow
through on the test or any subsequent steps needed before
the therapeutic … Volume 147 • Number 12 www.annals.org
stenosis in the general population, the generalizability of
treatment … Widespread screening for carotid ar-
tery stenosis would invariably lead to surgical treatment
provided … is unavailable, or when evidence about the ben-
efits of treatment is insufficient. … For
example, the benefits of prophylactic aspirin therapy
among men include fewer coronary heart events
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/We5A-uCMvX5qYeFukGgqks
March 01, 2004 - Good Newer treatments have achieved
treatment reduce the Well-designed sustained virologic response … with older treatments. Trials were
performed in patients referred for
treatment.
7b. … Good Common adverse events with
intolerance to treatment) Well-designed interferon-based therapy are … Combination
therapy (interferon alfa and ribavirin) in the
treatment of chronic hepatitis C: a rapid … Clinical
Therapeutics. 1994;16(2):334–343.
134. Zarski JP, Leroy V.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/hepatitis-c-virus-infection-screening-2004
March 08, 2004 - Combination therapy (interferon alfa and ribavirin) in the treatment of chronic hepatitis C: a rapid … Clinical Therapeutics 1994;16(2):334-43.
134. … interferon + ribavirin) compared with older treatments. … treatment and may not benefit from further therapy. 116 Normalization of aminotransferase levels (biochemical … Presence of HCV RNA at the end of treatment is highly predictive of relapse when therapy is stopped.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/efwy72cuMdhcF2jotkhTzC
March 29, 2019 - significantly following the implementation of
routine prenatal HIV screening and the use of effective therapies … significantly following the
implementation of routine prenatal HIV screening and the use of
effective therapies … Initiation
of antiretroviral therapy at high CD4+ cell counts
is associated with positive treatment outcomes … Risk of
cardiovascular events associated with current
exposure to HIV antiretroviral therapies in a US … highly active antiretroviral therapy during
pregnancy.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/vmHooQ6ABG9CagdUXv2_rx
August 25, 2021 - Treatment interventions to lower lipid levels generally include life-
style modification (eg, changes … • The USPSTF found adequate evidence that the harms of treatment of familial hypercholesterolemia or … USPSTF reviewed 22 fair- to good-quality trials (n = 2257)
examining the effectiveness of lipid-lowering treatments … good-quality trials (n = 1008) examining the
effectiveness of various nonpharmacologic lipid-lowering
treatments … • Long-term data on the harms of screening and treatment.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/TkWNoq6KQb3SoZ54gscLCQ
July 25, 2016 - Based
on 18 trials (n = 2972), antiviral therapy compared with placebo or no treatment was
associated … therapies to achieve intermediate outcomes. … Antiviral Therapy vs Placebo or No Treatment
Eighteen trials (n = 2972) reported effects of antiviral … Antiviral Therapy vs Placebo or No Treatment
Seven randomized trials of antiviral therapy vs placebo … Antiviral Treatment vs Placebo or No Treatment on Health Outcomes
Favors
antiviral
therapy
Favors
placebo