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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/screening-for-prediabetes-and-type-2-diabetes
November 15, 2018 - improve health outcomes compared with no intervention, usual care, or interventions with different treatment … improve health outcomes compared with no intervention, usual care, or interventions with different treatment … threshold)
KQs 4, 5: No intervention, placebo, usual care (can include minimal intervention), different treatment … , harms from false-positive results, burden, inconvenience, depression, and unnecessary testing and treatment … KQ 6: Serious side effects from treatment, including mortality, myocardial infarction, stroke, cancer
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-section-7-formulation-task-force-recommendations
in context (clinical context, societal values for specific outcomes, and context of intervention and treatment … the population of interest, recommendation, risk assessment, screening or intervention of interest, treatment
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hepatitis-b-virus-infection-screening
March 14, 2019 - Interventions
KQs 1–3: Screening, including alternative screening strategies (KQ 3)
KQs 4–7: Antiviral treatments … Therapies will be classified as:
Preferred: Pegylated interferon (adults), nonpegylated interferon … tenofovir alafenamide
Nonpreferred: Lamivudine, adefovir, and telbivudine
KQs 4–7: Antiviral treatments … not approved by the FDA; combination therapy
Comparators
KQs 1, 2: No screening
KQ 3: … nonpreferred antiviral therapies
KQ 7: Effects on intermediate outcome (HBV DNA level, HBeAg status
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hepatitis-c-screening
December 21, 2017 - What are the harms of currently recommended antiviral treatments? *
9. … 7, and 8 include those defined by age, race/ethnicity, sex, drug use, receipt of maximally assisted therapy … What is the effect of antiviral treatments on behavioral outcomes? … clinical outcomes (KQ 9)
Populations
Persons with HCV infection being treated with antiviral therapy … behavioral health care; subpopulations of interest include drug use, persons using medication-assisted therapies
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/gWJU-ZynehGyLBVYtDmMow
May 01, 2009 - , 3%
received delayed treatment, 3% declined treatment, and
2% were lost to follow-up. … syphilis before or
during pregnancy, including 22.6% who did not have an
adequate serologic response to therapy … Compared treatments or
supplements used by at least
0.5% of pregnant women
during critical periods who … failed, 5 to women who declined treatment,
and 7 to women who received late
treatments. … Previous reports of 1–5 anaphylactic
reactions per 100 000 treatments.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/E24AtkYp7cR8bp864K4CGS
January 01, 2025 - www.niams.nih.gov/health-topics/osteoporosis
https://www.niams.nih.gov/health-topics/osteoporosis/diagnosis-treatment-and-steps-to-take
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/latent-tuberculosis-infection-screening
June 17, 2021 - or who had received no more than a few weeks of treatment. … observed therapy for 6 or 9 months, RIF daily for 4 months, or INH plus RPT weekly by directly observed … therapy for 3 months) compared with placebo, no treatment, delayed treatment, or another eligible treatment … KQs 3, 5: Studies comparing other treatments or combinations (i.e., regimens that are not recommended … KQ 4: False-positive results leading to unnecessary testing or treatment, labeling, stigma, anxiety,
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan97/breast-cancer-screening-january-2016
July 17, 2014 - carcinoma in situ, atypical ductal or lobular hyperplasia); or previous large doses of chest radiation therapy … carcinoma in situ, atypical ductal or lobular hyperplasia); or previous large doses of chest radiation therapy … density, parity, race/ethnicity, age at first birth, menopausal status, current use of menopausal hormone therapy … situ, atypical ductal or lobular hyperplasia); or women with previous large doses of chest radiation therapy … adverse effects of treatment, quality of life measures, other measures of impairment).
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan21/chlamydia-and-gonorrhea-screening-september-2014
June 15, 2013 - adverse events, they may be diagnosed with a gonococcal or chlamydia infection, and they may go through treatment … The treatment could lead to reduced complications of the gonococcal or chlamydial infection, and it may … The treatment could lead to reduced complications of the gonococcal or chlamydial infection and to reduced … The treatment could also lead to reduced tramsmission of the infection to the newborn, and it may lead … Treatment harms will be discussed in the background section of the systematic review.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/kHT3WGUaG2wTz2pF_ke7bn
fractures)
Fracture-related morbidity (e.g.,
disability)
KQ3:
Overdiagnosis resulting in
unnecessary treatment … fractures)
Fracture-related morbidity (e.g.,
disability)
KQ3:
Overdiagnosis resulting in
unnecessary treatment … population for model
validation
Harms:
Overdiagnosis resulting in
unnecessary treatment
Radiation … population
Bisphosphonates with
FDA-approved
indications for the
treatment of
osteoporosis (i.e … gastrointestinal cancer, serious
gastrointestinal events, rebound
fractures after discontinuing
denosumab treatment
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/food-insecurity-screening
March 11, 2025 - more. 17-19 It is derived from, and validated against, the USDA Household Food Security Survey. 19
Treatment … , primary interest in other outcomes or comparative effectiveness). 3 , 33
Harms of Screening and Treatment … Primary care–based and primary care–referrable interventions generally offer only limited “treatment” … Benefits of early detection and intervention and treatment
Inadequate direct evidence about screening … Harms of early detection and intervention and treatment
Inadequate evidence on the harms of screening
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/VwvmgA5bLZZJhK6YSqRonU
November 01, 2022 - • Treatment with continuous positive airway pressure or mandibular advancement devices can improve … apnea-hypopnea index, Epworth Sleepiness Scale score, and blood pressure) in populations referred for
treatment
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/2021-uspstf-annual-report-to-congress.pdf
January 01, 2021 - • Assess the effects of lifestyle interventions and medical treatments for screen-detected
prediabetes … Potential harms may include inaccurate
test results, harms from invasive followup tests, harms from treatment … • Assess the effects of lifestyle interventions and medical
treatments for screen-detected prediabetes … Final
Research Plan
Menopausal Hormone
Therapy to Prevent
Chronic Conditions
Oral Health in Youth … Deficiency
Draft
Research Plan
Folic Acid to Prevent
Neural Tube Defects
Menopausal Hormone
Therapy
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-nonpregnant-adolescents-and-adults/human-immunodeficiency-virus-hiv-infection-screening
June 15, 2017 - . † Harms of treatment include adverse effects associated with antiretroviral therapy, including cardiometabolic … studies
KQ 5: Randomized, controlled trials and controlled observational studies; will consider treatment … diagnostic staging step, and clarify that the evidence review will focus on the benefits and harms of treatment … with antiretroviral therapy. … therapy regimens."
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-pregnant-women/human-immunodeficiency-virus-hiv-infection-screening
June 15, 2017 - . † Harms of treatment include adverse maternal and infant outcomes associated with use of antiretroviral … therapy. … treatment interruption
Comparisons
KQs 1, 3: HIV screening vs. no screening
KQ 2: Repeat … the USPSTF revised the analytic framework to differentiate the harms of screening from the harms of treatment … diagnostic staging step, and clarify that the evidence review will focus on the benefits and harms of treatment
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan104/skin-cancer-screening-july-2016
July 17, 2014 - Finally, key question 6 addresses the harms that are associated with the treatment of skin cancer by … What are the harms of surgical treatment of skin cancer?
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/osteoporosis-screening-june-2018
November 05, 2015 - For adults with increased risk for osteoporotic fractures, treatment may reduce the likelihood of fractures … Treatment may result in harms (KQ 5). … What are the harms associated with treatment with pharmacotherapy? … Food and Drug Administration for the treatment or prevention of osteoporosis (including bisphosphonates … , estrogen agonists/antagonists, hormone therapy, calcitonin, parathyroid hormone, and RANKL inhibitors
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/tfcongresstestimony%20(3).pdf
November 30, 2016 - and because many sub-specialists have specific
ties to the industries that make screening tests or treatments … that I can give Ruth a complete understanding of potential side effects of these tests
3
and treatments … Those providers whose livelihoods are affected by
the diagnosis and treatment of disease—as is the … specific ties (including as consultants or speakers) to the industries that make screening tests
or treatments
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/prostate-cancer-screening
April 28, 2016 - varying the age at which to start/stop screening, the screening interval, the threshold for biopsy, and treatments … (androgen deprivation therapy via luteinizing hormone-releasing hormone agonists, antiandrogen therapy … , and/or orchiectomy)
Ultrasonography (high-intensity focused ultrasonography)
Radiation therapy … (external-beam radiation therapy, proton beam therapy, brachytherapy, combination therapies)
Ablative … prostate hyperplasia) that are not generally associated with an increased risk for prostate cancer. 1
† Treatments
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/8YfPLRoMwTeaDgxJdYnYbb
September 24, 2019 - identified 5.0% of women who were
screened with dip slide as positive for asymptomatic bacteriuria.33
Treatments … women reported that there were no adverse
drug reactions among the 49 women treated with nitrofurantoin
therapy … women treated
with trimethoprim.28 Another reported that 2 of 32 women (6%)
assigned to daily ofloxacin therapy … Therapy vs no therapy for
bacteriuria in elderly ambulatory nonhospitalized
women. … Urinary tract infections in pregnancy:
old and new unresolved diagnostic and therapeutic
problems.