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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hepatitis-b-virus-infection-screening
March 14, 2019 - Interventions
KQs 1–3: Screening, including alternative screening strategies (KQ 3)
KQs 4–7: Antiviral treatments … Therapies will be classified as:
Preferred: Pegylated interferon (adults), nonpegylated interferon … tenofovir alafenamide
Nonpreferred: Lamivudine, adefovir, and telbivudine
KQs 4–7: Antiviral treatments … not approved by the FDA; combination therapy
Comparators
KQs 1, 2: No screening
KQ 3: … nonpreferred antiviral therapies
KQ 7: Effects on intermediate outcome (HBV DNA level, HBeAg status
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/VwvmgA5bLZZJhK6YSqRonU
November 01, 2022 - • Treatment with continuous positive airway pressure or mandibular advancement devices can improve … apnea-hypopnea index, Epworth Sleepiness Scale score, and blood pressure) in populations referred for
treatment
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan21/chlamydia-and-gonorrhea-screening-september-2014
June 15, 2013 - adverse events, they may be diagnosed with a gonococcal or chlamydia infection, and they may go through treatment … The treatment could lead to reduced complications of the gonococcal or chlamydial infection, and it may … The treatment could lead to reduced complications of the gonococcal or chlamydial infection and to reduced … The treatment could also lead to reduced tramsmission of the infection to the newborn, and it may lead … Treatment harms will be discussed in the background section of the systematic review.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/s2xawZNAWVC5qgGyTT6r8m
October 01, 2015 - as a result of intervention and improvement in child health
outcomes, as well as screening for and treatment … Benefits of Early Detection and
Treatment
The USPSTF found inadequate
evidence on the effect of routine … Harms of Early Detection and
Treatment
The USPSTF found inadequate
evidence on the harms of routine … The USPSTF found
inadequate evidence on the harms of
treatment of iron deficiency anemia
in children … iron overdose can occur in
children receiving treatment or
supplementation with iron.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/latent-tuberculosis-infection-screening
June 17, 2021 - or who had received no more than a few weeks of treatment. … observed therapy for 6 or 9 months, RIF daily for 4 months, or INH plus RPT weekly by directly observed … therapy for 3 months) compared with placebo, no treatment, delayed treatment, or another eligible treatment … KQs 3, 5: Studies comparing other treatments or combinations (i.e., regimens that are not recommended … KQ 4: False-positive results leading to unnecessary testing or treatment, labeling, stigma, anxiety,
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/gWJU-ZynehGyLBVYtDmMow
May 01, 2009 - , 3%
received delayed treatment, 3% declined treatment, and
2% were lost to follow-up. … syphilis before or
during pregnancy, including 22.6% who did not have an
adequate serologic response to therapy … Compared treatments or
supplements used by at least
0.5% of pregnant women
during critical periods who … failed, 5 to women who declined treatment,
and 7 to women who received late
treatments. … Previous reports of 1–5 anaphylactic
reactions per 100 000 treatments.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-pregnant-women/human-immunodeficiency-virus-hiv-infection-screening
June 15, 2017 - . † Harms of treatment include adverse maternal and infant outcomes associated with use of antiretroviral … therapy. … treatment interruption
Comparisons
KQs 1, 3: HIV screening vs. no screening
KQ 2: Repeat … the USPSTF revised the analytic framework to differentiate the harms of screening from the harms of treatment … diagnostic staging step, and clarify that the evidence review will focus on the benefits and harms of treatment
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-nonpregnant-adolescents-and-adults/human-immunodeficiency-virus-hiv-infection-screening
June 15, 2017 - . † Harms of treatment include adverse effects associated with antiretroviral therapy, including cardiometabolic … studies
KQ 5: Randomized, controlled trials and controlled observational studies; will consider treatment … diagnostic staging step, and clarify that the evidence review will focus on the benefits and harms of treatment … with antiretroviral therapy. … therapy regimens."
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/NZcLsqV-5K7hyfot-qHQp9
November 01, 2004 - Although these cancers
recur frequently after treatment, they rarely invade
muscle and rarely cause clinically … The
effectiveness of treatment for those with high-grade
bladder cancer is uncertain.10 The variability … We then combined
bladder neoplasms with therapeutics/treatment (1,984
citations) and combined those results … Does treatment of early-stage
bladder cancer reduce morbidity and
mortality from this disease?
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/osteoporosis-screening-june-2018
November 05, 2015 - For adults with increased risk for osteoporotic fractures, treatment may reduce the likelihood of fractures … Treatment may result in harms (KQ 5). … What are the harms associated with treatment with pharmacotherapy? … Food and Drug Administration for the treatment or prevention of osteoporosis (including bisphosphonates … , estrogen agonists/antagonists, hormone therapy, calcitonin, parathyroid hormone, and RANKL inhibitors
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/visual-impairment-in-children-ages-1-5-screening-2011
January 15, 2011 - therapy of the non-affected eye. … treatment of the nonaffected eye. … referrals because of false-positive screening results, and unnecessary use of corrective lenses or treatments … amblyopia. 14
Five fair-quality trials with children ≥3 years of age demonstrated that some amblyopia treatments … regimens. 1
Evidence on adverse psychosocial effects of amblyopia treatments is limited.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/osteoporosis-screening
January 14, 2025 - The US Food and Drug Administration has approved several drug therapies for the treatment or prevention … For these reasons, it may be reasonable to avoid strict application of risk assessment tool treatment … Evidence on harms of drug therapies in men is limited. 1
Current Practice
Data on how frequently … The clinician's guide to prevention and treatment of osteoporosis. … Fracture risk and zoledronic acid therapy in men with osteoporosis.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan104/skin-cancer-screening-july-2016
July 17, 2014 - Finally, key question 6 addresses the harms that are associated with the treatment of skin cancer by … What are the harms of surgical treatment of skin cancer?
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/uspstf-annual-report-to-congress-2019.pdf
January 01, 2019 - Gonococcal Ophthalmia Neonatorum: Preventive Medication
The USPSTF recommends prophylactic ocular topical … Considerations for Implementation: To determine whether a patient is a candidate for
statin therapy, … Considerations for Implementation: To determine whether a patient is a candidate for
statin therapy, … D
Hormone Therapy With Combined Estrogen and Progestin in Postmenopausal Women:
Primary Prevention … Gonococcal Ophthalmia
Neonatorum: Preventive
Medication
The USPSTF recommends prophylactic ocular topical
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/kHT3WGUaG2wTz2pF_ke7bn
fractures)
Fracture-related morbidity (e.g.,
disability)
KQ3:
Overdiagnosis resulting in
unnecessary treatment … fractures)
Fracture-related morbidity (e.g.,
disability)
KQ3:
Overdiagnosis resulting in
unnecessary treatment … population for model
validation
Harms:
Overdiagnosis resulting in
unnecessary treatment
Radiation … population
Bisphosphonates with
FDA-approved
indications for the
treatment of
osteoporosis (i.e … gastrointestinal cancer, serious
gastrointestinal events, rebound
fractures after discontinuing
denosumab treatment
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan97/breast-cancer-screening-january-2016
July 17, 2014 - carcinoma in situ, atypical ductal or lobular hyperplasia); or previous large doses of chest radiation therapy … carcinoma in situ, atypical ductal or lobular hyperplasia); or previous large doses of chest radiation therapy … density, parity, race/ethnicity, age at first birth, menopausal status, current use of menopausal hormone therapy … situ, atypical ductal or lobular hyperplasia); or women with previous large doses of chest radiation therapy … adverse effects of treatment, quality of life measures, other measures of impairment).
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/prostate-cancer-screening
April 28, 2016 - varying the age at which to start/stop screening, the screening interval, the threshold for biopsy, and treatments … (androgen deprivation therapy via luteinizing hormone-releasing hormone agonists, antiandrogen therapy … , and/or orchiectomy)
Ultrasonography (high-intensity focused ultrasonography)
Radiation therapy … (external-beam radiation therapy, proton beam therapy, brachytherapy, combination therapies)
Ablative … prostate hyperplasia) that are not generally associated with an increased risk for prostate cancer. 1
† Treatments
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/behavintr.pdf
January 01, 2010 - adapting
existing USPSTF methods to issues and challenges
raised by behavioral counseling intervention topical … Interventions to help
patients change unhealthy behaviors, like treatments
for patients with chronic … Further,
“counseling” is a broadly used but imprecise term
that covers a wide array of preventive and
therapeutic … activities, from mental health or marital
therapy to the provision of health education and
behavior … The future of smoking cessation therapy
in the United States.
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/annlrpt2013%20(4).pdf
November 01, 2013 - Potential harms also include side
effects or complications of treatments. … Results of these studies could be used to target depression treatments more effectively to increase benefits … Screening and Treatment for Depression in Children
3. … and prevention interventions, evaluations of the use and
cost effectiveness of tobacco cessation treatments … Ophthalmia Neonatorum: Preventive Medication for All Newborns
The USPSTF recommends prophylactic ocular topical
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/osteoporosis-screening
November 18, 2021 - Treatments that are no longer used in practice or that have been recalled, specifically calcitonin and … Nonpharmacologic treatments (e.g., exercise, fall prevention interventions). … † This review is not intended as a comprehensive review of all available pharmacologic therapies. … Second-line therapies (abaloparatide, teriparatide, romosozumab) are excluded for women because the USPSTF … hormone therapy, so they will not be included in this update