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Total Results: 1,424 records

Showing results for "topical treatment".

261. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/01_arthritis_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … MSC therapy has the potential to be a first-line OA-treatment option that could regenerate articular … As with MSC therapy, preparation ES-4 protocols and injection frequency vary among treatment … improvement provided by PRP for knee OA was 9 months. 27 Autologous PRP is not considered a drug or a therapeutic

262. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/analytic-frameworks.ppt
     December 09, 2009 - This overall analytic framework includes both screening and treatment; the box surrounds the portion … of the framework that would be used if the intervention being reviewed was the treatment, rather than … Population Intervention Outcomes Sample Screening and Treatment Framework This slide is intended to … Treatment of Overactive Bladder in Women. … Treatment of Overactive Bladder in Women.

263. Peripheral-Artery-Disease-Treatment Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
     January 31, 2013 - (2) Medical therapy Selected medical therapies have been shown to improve walking distance. … treatments. … Does the effectiveness of treatments vary by use of exercise and medical therapy prior to invasive management … currently in use (such as specific components of treatments considered to be “optimal medical therapy … Does the effectiveness of treatments vary by use of exercise and medical therapy prior to invasive management

264. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_june_2012.pdf
     January 01, 2012 - Many patients with T2DM do not meet treatment goals and require additional therapy with one of two … Adherence  Key Facts: Two therapies are in development for treating T2DM to improve efficacy, … for T2DM, especially potentially curative treatments such as bariatric surgery. … One expert with a clinical perspective also noted that initiation of treatment with this therapy might … Both treatments were generally well tolerated.

265. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0319_06-17-2009.pdf
     January 01, 2009 - sepsis can differ with regards to inciting organism, focus of infection, and response to antibiotic treatments … sensitivity and specificity for identifying the disease, predicting patient outcomes, and reliably guiding treatment …  Given that procalcitonin is increasingly being used to guide treatment-related decisions regarding

266. Methods Guide for Comparative Effectiveness Reviews - Expanded Guidance on Selected Quantitative Synthesis Topics (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
     March 01, 2013 - The control rate may be affected by disease severity, concomitant treatments, followup duration, as … slope for the regression of treatment effect on control rate is non-zero. … with those not receiving the treatment. … compared with those not receiving the treatment. … rate of an event in patients not receiving the treatment.

267. Future Research Needs for the Comparative Effectiveness of Breathing Exercises and/or Retraining Techniques in the Treatment of Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment-future_research.pdf
     September 01, 2012 - First, this area of research – the use of breathing techniques and even complementary and alternative therapies … agenda related to the use of breathing techniques and exercises and other complementary and alternative therapies … Breathing and mild physical exercise therapy for asthma. … Heart rate variability biofeedback: its role in asthma therapeutics. … research, new-to-the-field thinking o Relevance to asthma: potential for new insights into causes and treatments

268. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pain-chronic_disposition-comments.pdf
     September 01, 2011 - know that the cultures are very different as is their way of life which would impact the response/therapies … A possible list could include NSAIDs, acetaminophen, topical agents, serotonin- norepinephrine reuptake … paragraph above, but also because the interventions listed under “Physical reconditioning” include “Graded therapeutic … Another “next step”, given the cost of “interventional” pain therapies, would be to address the costs … treatments particularly interventional/ unimodal approaches.

269. #05 DEPRESSION (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1312.pdf
     October 01, 2014 - therapy or repetitive transcranial magnetic stimulation as second- and third-line therapies for BPD … DBS is expected to be positioned as an additional therapeutic option for patients who have treatment-resistant … They cited suboptimal treatments, lack of an FDA-approved treatment for this condition, and the condition … DBS therapy is incompatible and contraindicated with some other device-based depression treatments, … , which could provide a therapeutic advantage over standard antidepressants with delayed therapeutic

270. Disposition of Comments for CER 195 Management of Uterine Fibroids (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-195-disposition-comments-uterine-fibroids.pdf
     December 14, 2017 - Reviewer #2 Executive Summary although these symptoms can be prevented with hormonal 'add back' therapy … The review "does not cover preoperative or adjunctive treatments." … Public Reviewer (Allergen) Background The first US Phase III trial indicates that medical therapy … system, eye care, medical aesthetics, gastroenterology, urology, cardiovascular, and anti-infective therapeutic … between very different treatments.

271. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1412.pdf
     October 01, 2015 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … Therapies targeting CFTR mutations have been proposed to treat CF; however, therapies targeting molecular … Additionally, 4.2% of patients who received combination therapy discontinued treatment because of adverse … However this expert also noted as more targeted therapies with high treatment costs emerge, payers

272. PowerPoint Presentation (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-frameworks.ppt
     June 01, 2012 - Is there heterogeneity of test accuracy and treatment effect (i.e., do accuracy and treatment effects … research into six different domains: Technical efficacy Diagnostic accuracy Diagnostic thinking efficacy Therapeutic … research into the domains of technical efficacy, diagnostic accuracy, diagnostic thinking efficacy, therapeutic … Key outcomes: Are related to the effectiveness of HER2-targeted therapy in this subgroup. … This therapy includes surgery and adjuvant chemotherapy with HER2-targeting agents.

273. PowerPoint Presentation (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-frameworks.ppt
     June 01, 2012 - Is there heterogeneity of test accuracy and treatment effect (i.e., do accuracy and treatment effects … research into six different domains: Technical efficacy Diagnostic accuracy Diagnostic thinking efficacy Therapeutic … research into the domains of technical efficacy, diagnostic accuracy, diagnostic thinking efficacy, therapeutic … Key outcomes: Are related to the effectiveness of HER2-targeted therapy in this subgroup. … This therapy includes surgery and adjuvant chemotherapy with HER2-targeting agents.

274. Disposition of Comments for Treatments for Seasonal Allergic Rhinitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_disposition-comments.pdf
     July 17, 2013 - Introduction Many patients don’t take medications for 2 straight weeks for SAR; they use intermittent therapy … Thus, because of early onset of action (not really discussed in this draft document because the therapeutic … such as growth retardation and HPA suppression without any citations…should state that the highly topical … that have solid scientific support and a caution that the impact of our drug therapies may not be … This can guide a formulary committee to make a few general decisions re sequencing therapeutic decisions

275. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/devdelays_adhd_autism_hi_impact.pdf
     January 01, 2012 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … with current treatments could promote demand for HBOT as an adjunct treatment for ASDs, especially … therapies. 10 Popchilla, a character-assisted therapy robot, is intended to assist therapists trained … Hyperbaric oxygen therapy. [internet].

276. #05 DEPRESSION (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … efficacy for suicidal ideation and as an adjunct treatment to behavior and brain-stimulation therapies … Double-blind, placebo-controlled trial of ketamine therapy in treatment-resistant depression (TRD … Proof-of- concept trial of ketamine therapy in treatment- resistant depression (RAPID). … Therapeutic options in treatment-resistant depression. Ann Med. 2011 Nov;43(7):512-30.

277. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - Many patients with T2DM do not meet treatment goals and require additional therapy with one of two … Despite combined hypoglycemic therapy, many patients with T2DM can still fail to meet treatment goals … Both treatments were generally well tolerated. … Despite combined hypoglycemic therapy, many patients with T2DM can still fail to meet treatment goals … ITCA 650 for zero-order continuous delivery of exenatide at therapeutic levels using 3-, 6-, and

278. Future Research Needs for Diagnosis of Obstructive Sleep Apnea (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
     February 01, 2012 - A better definition of OSA syndrome will more specifically target therapy at those who are at risk and … Other issues that should be considered are the patients’ costs for using OSA treatments. … Phased treatment combinations should also be considered. … patterns compared to other physicians with respect to prescriptions, education, and adherence to CPAP therapy … Diagnosis and Treatment of Obstructive Sleep Apnea in Adults.

279. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … No effective treatments are available to improve long-term nutritional absorption other than intestinal … is refractory to current therapies, the experts agreed. … Endoscopic therapies for gastroesophageal reflux disease (GERD). Policy number: 2012T0322K.

280. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0332_07-29-2010.pdf
     January 01, 2010 - Topic Number(s): 0283 Document Completion Date: 11-16-10 2 (active surveillance vs. active treatment … Does use of the PCA3 assay influence treatment decisions in men with positive biopsies? i. … Avoidance of unnecessary treatment in men with clinically insignificant prostate cancer ii. … Initiation of treatment in men with a high probability of clinically significant prostate cancer c … Potential for morbidity related to altered screening/management (e.g., biopsy, repeat biopsy, adjuvant therapy