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Total Results: 1,424 records

Showing results for "topical treatment".

181. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … Pharmacologic therapies can address symptoms of hyperactivity and depression, but effective pharmacologic … Cypress Bioscience acquires novel intranasal carbetocin therapy for autism; therapy may represent … Autism treatments and drugs. [internet].

182. Disposition of Comments CER 194 Intermittent Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
     March 19, 2018 - If all patients adhered 100% to therapy, intermittent therapy and the need to add more and more controllers … This review is focused on the class comparison of these therapies. … include patients 6 years old and above BI appreciates AHRQ’s thorough review of currently available therapeutic … The results “no difference” means that statistically, there was no difference in the two therapies … We avoid using terms such as “similar” so as not to convey equivalence of therapies.

183. Disposition of Comments Report for Treatment of Atrial Fibrillation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_disposition-comments.pdf
     June 28, 2013 - For example, patients randomized to an initial 100J shock would be required to receive subsequent treatments … The focus in our CER is on acute phase cardioversion, but because the therapeutic effects of oral antiarrhythmic … are these people that fail Pharmacological therapies? … For example, patients randomized to an initial 100J shock would be required to receive subsequent treatments … assigned, after successful AV junction ablation and pacing treatment, to no antiarrhythmic drug therapy

184. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1506.pdf
     November 01, 2016 - new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care delivery innovations that address … or payers may require a step-therapy approach starting with existing endometriosis treatments before … or payers may require step therapy in which patients try existing endometriosis treatments before … Experts noted its anticipated higher cost than alternative therapies available as generics may increase

185. Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia_research.pdf
     January 01, 2013 - regimen (i.e., repletion or continuous treatment) o Interactions between treatments (i.e., patients … regimen (i.e., repletion or continuous treatment) • Interactions between treatments (i.e., patients … o Most of the reported harms were attributed to iron therapy. Key Question 3. … regimen (i.e., repletion or continuous treatment) o Interactions between treatments (i.e., patients … , there may be insufficient immediately available iron to optimize ESA therapy.

186. Disposition of Comments: CER 227 Noninvasive Nonpharmacological Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-227-noninvasive-nonpharm-chronic-pain-comments.pdf
     April 16, 2020 - Osteopathic manipulation treatment versus therapeutic exercises in patients with chronic nonspecific … Restorative therapies evaluated in the HHS Task Force include: • Therapeutic Exercise. … • Transcutaneous Electric Nerve Stimulation • Massage Therapy • Traction • Cold and Heat • Therapeutic … therapies and that the decision for any course of pain treatment should be based upon the individual … There appear to be some comparators to analgesic treatment, such as acetaminophen or topical analgesics

187. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0405_01-16-2011.pdf
     January 01, 2011 - desires an evidence review on the comparative effectiveness of tools to assess cough severity and treatments … Intervention(s): Instruments/tools used to assess cough severity and treatments for cough. … of life; complications caused by coughing; and adverse reactions to cough therapies. … What is the best way to assess cough severity and the efficacy of cough therapies? 2. … Which cough therapies should be prescribed for a cough (per population, cough severity, cough etiology

188. Disposition of Comments for CER 202 Effectiveness and Safety of Bronchial Thermoplasty in the Management of Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-202-thermoplasty-comments.pdf
     December 14, 2017 - Bronchial Thermoplasty: Therapeutic Success in Severe Asthma Associated with Persistent Airflow Obstruction … The investigators also analyzed the results just for those patients who actually got the treatments … context for the need for BT in a patient population not indicated for and/or not responsive to other treatments … does not include in the final sentence is that the sham arm had a ‘placebo’ effect due to the non- therapeutic … Bronchial Thermoplasty and Biological Tehrapy as Targeted Treatments for Severe Uncontrolled Asthma

189. Treatments for Adults with Schizophrenia: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
     September 23, 2016 - in selecting treatments. … (ACT) • Assisted outpatient treatment • Cognitive behavioral therapy for psychosis (CBTp) • Cognitive … the studies, or nonactive/sham comparators, which act as a control for the non-specific effects of therapy … Psychosocial and other nonpharmacological treatments include assertive community treatment (ACT), assisted … outpatient treatment, cognitive behavioral therapy for psychosis (CBTp), cognitive remediation, family

190. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0012_03-21-2008.pdf
     January 01, 2008 - If a patient is asymptomatic, is there benefit from the patient perspective for treatment? 3. … What are the potential harms from treatment and non-treatment? … Does treatment make a difference in morbidity or mortality when sub-clinical hypothyroidism or hyperthyroidism … What are the harms of treatment of sub-clinical hypothyroidism and sub-clinical hyperthyroidism? … further large randomized controlled studies are necessary in order to evaluate the effectiveness of treatment

191. Disposition of Comments for Chronic Urinary Retention: Comparative Effectiveness and Harms of Treatments (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-urinary-retention_disposition-comments.pdf
     September 15, 2014 - that in this industry sponsored study that there probably were differences in PVR between the two therapies … The “treatment” of CUR in the neurogenic population is misguided with the goals of therapy, even on … This is true; we found no studies that evaluated the treatment of CUR that were not also treatments … information to clinicians they can use to help guide patients in choosing between the available therapies … Discussion The conclusion that TURP and microwave therapy are similarly effective in the treatment of

192. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0265_02-29-2008.pdf
     January 01, 2008 - Pain treatment needs to be multi-modal, what treatments are there? 2. … Is there a model that might be effective for multi-modal treatment that might work in a large system … How to explain gender disparities in response to pain treatment (psych, estrogen, etc.)? 7. … Is there evidence that treatment effectiveness varies by patient population? 11. … Which patient factors are associated with improved response to treatment?

193. Topic 0451 Celiac Disease NSD FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-533_05-24-2013.pdf
     January 01, 2013 - follow-up testing; iii. invasive procedures (biopsies); iv. cases diagnosed; v. patients complying with treatment … ; and vi. response to treatment. 5.

194. AHRQ Evidence-based Practice Center Program Research Gaps Summary: Primary Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
     March 01, 2022 - • Evidence on whole-plant cannabis products with lower THC than CBD levels (topical CBD), other … product • Studies to compare different routes of administration (e.g., oromucosal spray, oral oil, topical … , including opioid therapy, nonopioid pharmacologic therapy, and nonpharmacologic therapy. … o Hip osteoarthritis: Exercise, manual therapies. … but still may lead to discontinuation of therapy during treatment of up to 12 weeks

195. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2023 Update of the Evidence Base for the PTSD Trials Standardized Data Repository (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2023-update-executive-summ.pdf
     January 01, 2023 - Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2023 Update of the Evidence … Trials Standardized Data Repository Systematic Review Pharmacologic and Nonpharmacologic Treatments … the previous AHRQ report1 by identifying and abstracting data from newly published RCTs examining treatment … Results In this update, we added 60 RCTs examining treatments for PTSD for a total of 496 included … that allows clinical, research, education, and policy stakeholders to understand current research on treatment

196. Disposition of Comments for CER 201 Effectiveness of Indoor Allergen Reduction in the Management of Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-asthma-disposition-comments.pdf
     February 15, 2018 - Management of Asthma Source: https://effectivehealthcare.ahrq.gov/topics/asthma-nonpharmacologic-treatment … Would suggest a statement in the report (likely in Intro) as to why these 2 unrelated therapies are … Children in the treatment group experienced improvement on all five outcomes. … Would suggest a statement in the report as to why these 2 unrelated therapies are being presented together … Because treatment was applied inconsistently, we are concerned that the current classification level

197. Executive Summary_Systematic Review_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2022 Update of the PTSD-Repository Evidence Base (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-executive-summ.pdf
     January 01, 2022 - Executive Summary_Systematic Review_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress … of the PTSD-Repository Evidence Base Systematic Review Pharmacologic and Nonpharmacologic Treatments … previous work;1,3,4 the purpose of this report is to identify and abstract data from RCTs examining treatment … that allows clinical, research, education, and policy stakeholders to understand current research on treatment … Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2022 Update of the

198. pneumonia-antibiotic-treatment-protocol-130718 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
     July 19, 2013 - • Transport from the ICU for diagnostic or therapeutic procedures • Previous antibiotic exposure, … These factors are essential to understanding and choosing an effective therapeutic regimen, and they … Equivalency OR Absorption OR Distribution OR Metabolism OR Excretion OR Protein Binding OR Therapeutic … Index OR Trough OR Peak OR Therapeutic Drug Monitoring) Pharmacodynamics (Terms for Pharmacodynamic … Correlation of antimicrobial pharmacokinetic parameters with therapeutic efficacy in an animal model

199. Topic 0505 Genetic Testing for Developmental Diseases NSD FINAL_SJ (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0594-131115.pdf
     March 13, 2013 - genetic testing Comparator(s): Other genetic testing/no genetic testing Outcome(s): Changes to child treatment … improved outcomes Key Questions Does the identification of the genetic etiology for DD/ID or ASD improve treatment …  There is currently not enough evidence that that links genetic testing to meaningful treatment changes

200. Topic 0583 Renal Masses and Localized Renal Cancer NSD FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0710-140625.pdf
     January 08, 2014 - Nomination The nominator is interested in developing a clinical guideline on the management and Summary: treatment … Intervention(s): Multiple treatment and management strategies including radical nephrectomy (open and … associated with radical nephrectomy, partial nephrectomy, thermal ablation, and active surveillance in the treatment … cases of kidney cancer and 13,680 deaths from kidney cancer. § There are multiple management and treatment … Current clinical guidelines do not consider advancements such as new surgical procedures and new therapeutic