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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0215_01-06-2010.pdf
January 01, 2010 - Document Completion Date: 8-13-10
1
Results of Topic Selection Process & Next Steps
Treatment … Nominator: Individual
Nomination
Summary:
The nominator questions whether there are any effective treatments … No recent systematic review or practice guidelines were identified that address the
treatment of RLS … Because of the numerous treatments that are FDA approved or available off-label
for this condition, … any harms of these treatments, particularly in specific subpopulations such as elderly
patients.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0352_09-22-2010.pdf
January 01, 2010 - Date: 03-19-12
1
Results of Topic Selection Process & Next Steps
Perinatal depression treatment … of depression with antidepressants and other therapies during preconception
and pregnancy. … with antidepressants; use of other treatments, including cognitive behavioral therapy,
other counseling … Potential harms and benefits of depression treatment must be weighed against the potential
harms of … A review addressing perinatal depression treatment will be a good companion to an in-process
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effectivehealthcare.ahrq.gov/sites/default/files/fecal-incontinence_disposition-comments.pdf
March 21, 2016 - The
majority of the pharmacologic methods evaluated, meaning
the topical medications are almost never … Treatments for FI
are imperfect and treatment combinations are
common. … Combination therapy with biofeedback, loperamide, and
stool-bulking agents is effective for the treatment … engaging patients in a conversation about risks
and benefits of each therapeutic option is important … We agree that some treatments (such as topical
medications) are rarely used because evidence
shows
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
June 23, 2014 - We separated physically-based somatic treatments, such as
electroconvulsive therapy, into a third category … How do pharmacologic treatments (monotherapy or combination therapies) affect
patient centered outcomes … How do pharmacologic treatments (monotherapy or combination therapies) affect
patient centered outcomes … How do somatic treatments (electroconvulsive therapy (ECT), transcranial
magnetic stimulation (TMS)) … and social rhythm therapy
• Psychoeducation
• Chronotherapy
Somatic treatment treatment
• Electroconvulsive
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_disposition-comments.pdf
January 26, 2015 - Similar concerns about lack of mind/body
therapies (ref Mist, SD, Complementary and alternative
exercise … TEP Reviewer 2
ES Results Under psychological therapies, there are 5 mindfulness
based stress reduction … and/or available in
the US with this restriction is remote,
especially for conventional medical therapies … content
will be informative to policy and make it clear that there is
no data to support some clinical therapeutic … Response
Peer Reviewer 2 General Given the paucity of data about the topic and the nature of
the therapeutic
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_disposition-comments.pdf
December 11, 2012 - Peer Reviewer #6 Executive
Summary
Page 10, Line 39: With regard to hormonal therapy, this treatment … There are no approved hormonal
treatments for UDT, either to stimulate testicular descent or to improve … What is the comparative effectiveness of
surgical therapies (one-stage vs. twostage, laparoscopic vs … Unfortunately, we did not encounter any reports
that met our inclusion criteria comparing
treatments … Peer Reviewer #3 General This is a generally useful review of the current diagnostic and therapeutic
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0359_10-15-2010.pdf
January 01, 2010 - Patients with multiple sclerosis or clinically isolated syndrome
Intervention(s): Disease-modifying therapies … for delay of relapse and disability,
treatments to address symptoms of multiple sclerosis, including … pharmaceutical and
non-pharmaceutical treatments
Comparator(s): Comparative effectiveness of disease-modifying … therapies, comparative
Diagnosis and Treatment of Multiple Sclerosis
Nomination Summary Document … There is no cure for MS; treatments aim to reduce the frequency and
hasten recovery from relapses and
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0094_04-09-2009.pdf
January 01, 2009 - for
autism including occupational, speech, and physical therapies and drug effectiveness. … Areas of interest from the second nominator include combined treatments,
effectiveness of early interventions … Understanding the combined effectiveness of medical and behavioral
treatments
a. … treatment plus a pharmacological treatment
versus pharmacological treatment alone in reducing depressive … clear that there is a real need for synthesized research that evaluates the
evidence base for various treatments
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/cervical-degenerative-protocol.pdf
January 12, 2022 - (e.g., radiofrequency ablation, exercise, physical therapy, heat therapy) with … Based on the comments made during the public posting of the KQs, we
added KQ2 to address add-on therapies … In patients with cervical degenerative disease, what are the comparative
effectiveness and harms of therapies … Treatments for Acute Pain: A Systematic Review. … Nonopioid Pharmacologic Treatments for Chronic Pain.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0075_03-10-2009.pdf
January 01, 2009 - The nominator
specifically mentions Remicade, Imuran, anti-inflammatories, and biologic therapies for … the treatment and management of Crohn’s disease. … Comparator(s): Comparisons of the above pharmacologic treatments. … What treatments or therapies, alone or in conjunction with one another, provide the
highest rate of … , and
the person’s response to previous medical treatments.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0365_10-28-2010.pdf
January 01, 2010 - The nominator expressed
interest in how the effectiveness of treatments may differ by factors such as … initiation, patient preferences and therapeutic values, and demographic
characteristics; and whether … psychotherapy
(including groupings of trauma-focused vs. not), to include complementary and
alternative therapies … pharmacotherapy, general and
specific types of psychotherapy (including complementary and alternative therapies … initiation, patient preferences and therapeutic values, and demographic characteristics).
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0351_05-10-2010.pdf
January 01, 2010 - and associated abnormalities and their impact on treatment and
outcomes. … cryptorchidism (undescended testicle)
Intervention(s): diagnostic methods (imaging, laparoscopy), hormone therapy … , surgical
therapy, specific surgical techniques, early treatment, follow-up care, counseling of
patient … of
treatment, medical therapies, different surgical techniques
Outcome(s): diagnostic ability … uncertainty regarding appropriate
diagnostic approaches for cryptorchidism as well as appropriate therapeutic
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0108_05-24-2009.pdf
January 01, 2009 - Completion Date: 1-12-10
1
Results of Topic Selection Process & Next Steps
Acute migraine treatment … IV Benadryl, Toradol, and Reglan in an emergency
department or clinical setting for acute migraine treatment … has been effective in treating migraines in patients and would like to see evidence
supporting this treatment … There appears to be significant clinical uncertainty surrounding acute migraine treatment in … A review specifically focused on the treatment combination posed by the nominator would not be
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0775-150722.pdf
May 12, 2015 - Comparator(s): Non-pharmacological treatments; all other treatment
options/variations (e.g., different … , electroconvulsive therapy). … Improvement Program [ATIP]), and somatic therapies such as
electroconvulsive therapy, or transcranial … therapies can be high. … treatment).
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0645-151012.pdf
August 05, 2015 - Also, understanding modifiers of treatment
and treatment pathways can help to optimize choices for patients … Decreased
medication side effects; decreased unintended consequences/harms associated with
therapies … What are modifiers of treatment and treatment pathways that can help to optimize
choices for patients … , including pharmacologic, psychosocial/behavioral (e.g., cognitive behavioral therapy), and
complementary … An updated synthesis of treatment
options can help to inform clinical decision-making.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0477_11-01-2011.pdf
January 01, 2011 - Nonpharmacologic therapies:
cardiovascular exercise; cognitive behavioral therapy (CBT); massage therapy … ; lifestyle
interventions; mind-body therapies; acupuncture
Comparator(s): Above interventions … unknown and because risk
factors for fibromyalgia are not well-understood, no curative or preventive treatments … therapies, and complementary and alternative (CAM) treatments … or
guideline that describes the comparative effectiveness of all available treatments for this condition
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effectivehealthcare.ahrq.gov/sites/default/files/nt_docs/topic-brief-updating-pharmacotherapy.pdf
September 30, 2022 - for AUDs (e.g., behavioral counseling, cognitive behavioral therapy,
motivational enhancement therapy … prospective cross-sectional study
also examined the effectiveness of Disulfiram and Naltrexone dual therapy … /
/drug therapy
Pharmacotherapy
OR
pharmacologic
From original review Naltrexone/
Acamprosate … "[MeSH Terms] OR "drug therapy"[MeSH
Subheading] OR ("naltrexone"[MeSH Terms] OR "naltrexone"[All Fields … the effectiveness of these treatments m...
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-final-report-update-2024-executive-summ.pdf
January 01, 2024 - Executive Summary_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2024 … is designed
to provide a broad range of stakeholders with up-to-date, comprehensive data on PTSD
treatment … the previous AHRQ report1 by identifying
and abstracting data from newly published RCTs examining treatment … elements that were infrequently reported include the duration of PTSD
diagnosis or symptoms, number of treatment-naïve … that allows clinical,
research, education, and policy stakeholders to understand current research on treatment
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_overview.pdf
March 27, 2014 - In childrena with JIA,b does treatment with DMARDs,c compared to
conventional treatment (i.e., NSAIDs … d Conventional treatments evaluated are: betamethasone, triamcinolone acetonide, triamcinolone hexacetonide … comparisons of one DMARD versus another, rather than on comparisons of DMARDs versus
conventional treatments … Pediatric Quality of Life Inventory Rheumatology Module (PedsQL-RM)
Composite measures of response to therapy … of Juvenile Idiopathic Arthritis:
Recommendations for the Medical Therapy of Children with Systemic
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0128_07-01-2009.pdf
January 01, 2009 - of Topic Selection Process & Next Steps
Generic versus brand name antiepileptic drugs for the treatment … of epilepsy will be addressed as part
of a larger in-process systematic review on treatment of epilepsy … Nomination
Summary:
The nominator is interested in the use of generic medications for the treatment … In addition, many states include these drugs in their narrow
therapeutic index laws. … The EHC Program has
initiated a systematic review of epilepsy treatment which will include the issue