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effectivehealthcare.ahrq.gov/sites/default/files/ch_4-user-guide-to-ocer_130129.pdf
January 01, 2010 - Exposure Definition and Measurement
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A D G
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Figure … In
panel E, the exposure is a single event in time with
an immediate effect that diminishes over time … Creating an Exposure
Definition
Time Window
A key component in defining exposure is the time
period
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-263-postpartum-hypertensive-pregnancy-executive-summary.pdf
May 01, 2023 - Probably increases the likelihood of obtaining blood pressure (BP)
measurements during recommended time … with standard (>24 hour) regimens:
Reduce the duration of urinary catheterization (high SoE), the time … Shorter duration MgSO4 regimens decrease urinary catheterization time (4 RCTs,
high SoE), time to ambulation … (2 RCTs, high SoE), time to breastfeeding (2 RCTs,
moderate SoE), and time from delivery to contact … (High SoE), time to breastfeeding
(Moderate SoE), and time from delivery to contact with the infant
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effectivehealthcare.ahrq.gov/sites/default/files/ch_2-user-guide-to-ocer_130129.pdf
January 01, 2011 - bias, which is introduced by defining the exposure
during the followup time versus the time prior to … This general principle also
applies to time-varying treatments for which the
followup time needs to … by factors that vary over time. … This observation time is
divided into treated person-time, a washout period
of person-time, and untreated … person-time.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-results-search-strategies-developed-with-without-text-mining-tools.pdf
March 01, 2021 - TMT searches
also reduced time spent in search strategy development. … It also increased the
average time required for the UP search but did not affect the average time required … Average UP and TMT time, sensitivity, and NNR without R5
Review Type Metric Time (hours) Sensitivity … It took experienced librarians less time to develop the
TMT searches than UP searches, and this time … estimate for that search in the overall time analysis.
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effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
January 01, 2013 - of potential immortal person-time bias and prevalent-user bias. … (time-varying exposure status) and carefully consider allocation of person-time to avoid immortal person-time … It is also possible to align the person-time and events appropriately by a choice of time scale in a … Time from disease onset to a treatment:
Pay careful attention to the time from initial diagnosis and … modalities is needed to prevent immortal person-time bias.
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effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
October 01, 2007 - ORIGINAL ARTICLE
Real-Time Vaccine Safety Surveillance for the Early
Detection of Adverse Events
Tracy … Objective: To develop and evaluate a new real-time surveillance
system that uses dynamic data files and … and control groups, we matched
control time windows to vaccinated time windows using
hierarchical rules … windows were matched
to control time windows. … This study highlights several other issues surrounding
use of real-time surveillance systems.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/clinical-care-rapid-review-appendix-c.xlsx
January 01, 2018 - Categorical outcome data of time to resolution for included studies
Evidence Table C-13. … Continuous outcome data of time to resolution for included studies
Evidence Table C-14. … Qualitative outcome data of time to resolution for included studies
Evidence Table C-15. … Lambert, 2016 2000 to 2013 US Interrupted time series Administrative, safety, and risk management data … Risk managers record data on each case in real time using a custom-built, online platform.
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effectivehealthcare.ahrq.gov/sites/default/files/considerations-for-statistical-chapter-10.pptx
January 01, 2013 - When time-varying covariates are affected by time-varying treatment, marginal structural models may be … Time-dependent Cox regression models can account for time-varying exposures and covariates. … However, difficult issues arise when both treatment and confounding variables vary over time. … Time-Varying Exposures/Covariates
Time-Varying Exposures/Covariates
In most comparative effectiveness … For time-to-event study outcomes, time-dependent Cox regression models can be used to account for time-varying
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effectivehealthcare.ahrq.gov/sites/default/files/ch_10-user-guide-to-ocer_130129.pdf
January 01, 2011 - In
addition, time-varying exposures and covariates should be accounted for to avoid bias. … When time-varying covariates are affected by
time-varying treatment, marginal structural models
(described … on CD4 count levels, which also
vary over time. … As noted above, for time-to-event study outcomes,
time-dependent Cox regression models can be
used … to account for time-varying exposures
and covariates.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/insomnia_clinician.pdf
August 01, 2017 - (���)
May reduce time awake after sleep
onset (���)
May improve (���) May improve some
outcomes … (���)
Zolpidemb May improve (���) Improves latency, total sleep time,
and sleep quality (���)
May … (���)
Reduces time awake after
sleep onset (���)
(���) (���)
Melatonin Agonists
Ramelteon (��� … , time awake after sleep onset, sleep efficiency, and sleep quality. … Sleep Restriction Interventions to limit time in bed to sleep time and to gradually increase time in
-
effectivehealthcare.ahrq.gov/sites/default/files/s149.pdf
October 01, 2007 - t � 1 but before taking a specific treatment at time t. … The majority of refills (2416
or 68%) could be considered to be “on-time,” with the
median time to filling … covariates and 18
time-varying covariates. … ; and (3) limited follow-up
time or a small treatment group. … Because the drug was only recently approved, we
had limited follow-up time.
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effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-2.xlsx
January 01, 2017 - Harms Outcomes Comments
Biem, 2003
Canada
Fair Vaginal prostaglandin E2 vs. vaginal prostaglandin E2 Time … 0.34 (95% CI 0.01 to 8.17) *For the inpatient group. the duration of hospital stay was defined as the time … For the outpatient group, it was the time from admission until discharge. … Foley catheter Total time from admission to delivery (*induction to delivery time; vaginal birth not … Cook catheter Total time from admission to vaginal delivery, h (SD): 14.25 (7.33) vs. 21.45 (5.30)
MD
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effectivehealthcare.ahrq.gov/sites/default/files/shah.pdf
May 29, 2025 - And, of course, it -- you know, it's a solution to the barriers of
geography and time as people are … with -- with particularly some of the larger medical
associations that we work with, at the same time … And, so, you can see this is sort of a -- a sort of distilled over time
about -- sort of distilled … Yes, we'll have plenty of time for questions and, like I
said in the sand box time as well, we can … You
know, they put a lot of investment and time into that.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-summary.pdf
August 01, 2023 - difference
++
Relief of SCC (Motor Function;
Regain Sphincter Control)
(Effect Size/SOE)a
Any time … + No evidence No evidence
Harms/AEs – Pathological
Fracture; New SCC
(Effect Size/SOE)a
Any time … evidence No difference
+ No evidence
Harms/AEs – Skeletal-related
Eventsc
(Effect Size/SOE)a
Any time … evidence
Harms/AEs – Adverse Events or
Reactions Not Otherwise Specified
(Effect Size/SOE)a
Any time … Impaired Bladder
or Bowel Function; Pain Flare;
Withdrawals due to AEs
(Effect Size/SOE)a
Any time
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_research-2012.pdf
January 01, 2012 -
Indicate the need to close the discussion on time, after giving a five minute “time
warning … Give participants a choice in how they spend their meeting time. … Give participants a choice in how they spend their meeting time. … Work on one issue at a time. … If there is to be another meeting, determine time, date and place.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/documentation-burden-prepub-disposition-comments.pdf
May 21, 2024 - In addition,
outcomes of burden need to measure actual time and
proportions of time spent with patients … related to clinical
documentation, inbox management, time spent in clinical
review, time spent in … Rather, it is the way that time is allocated
among patient-facing time and documentation. … Is “Time on EHR” time utilizing EHR? Is “Time
on Inbox” time utilizing Inbox? Etc. … Time Spent in Clinical Review—this is another time-
related measure area.
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effectivehealthcare.ahrq.gov/sites/default/files/clifford.pdf
May 29, 2025 - Evidence is driven by aggregated data over time, replicated. … So this might be a user who's using InstantMe from their
mobile all the time. … But at the same time, they bring your viral loads from 802,000
to 74. … And
we asked patients, did your doctor do this the last time you went and saw them? … time.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-covid-protocol.pdf
February 18, 2023 - COVID-19 rapid guideline: managing the long-term effects of COVID-19. … Memorandum on Addressing the Long-Term Effects of COVID-19. … https://www.whitehouse.gov/briefing-room/presidential-actions/2022/04/05/memorandum-on-addressing-the-long-term-effects-of-covid … https://www.whitehouse.gov/briefing-room/presidential-actions/2022/04/05/memorandum-on-addressing-the-long-term-effects-of-covid … Managing the long term effects of covid-19:
summary of NICE, SIGN, and RCGP rapid guideline.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/congestive-heart-failure-medicines_research.pdf
March 01, 2010 - to death from any cause and time to
the first VHA HF hospitalization following diagnosis. … Both outcomes were censored on
September 30, 2005, and time to first hospitalization was censored at … the time of death. … H0(3): There is no association between exposure to H-ISDN and either risk-adjusted time
to death or … Time-dependent
covariates in the Cox proportional-hazards
regression model.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-216-telehealth-evidence-summary.pdf
April 01, 2019 - – Specialty telehealth consultations likely reduce
patient time in the emergency department. … the use of information and
telecommunications technology to provide
or support healthcare across time … between
providers, often involving a specialist consultant,
or among clinical team members, across time … treatment, provider antibiotic
stewardship); volume of services; and healthcare
processes (e.g., time … to
Treatment (KQ2)
23 Time to treatment is shorter but not
significant in the majority of studies