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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/gestational-diabetes-screening
June 06, 2019 - Does treatment of GDM during pregnancy reduce poor health outcomes?
b. … Does treatment of GDM during pregnancy reduce poor intermediate outcomes?
c. … Does the effectiveness of treatment of GDM vary according to maternal subgroup characteristics, including … What are the harms of treatment of GDM, including severe maternal and fetal/neonatal hypoglycemia, delivery … , including but not limited to dietary advice, physical activity, blood glucose monitoring, insulin therapy
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/syphilis-infection-in-pregnancy-screening
May 13, 2025 - The evidence review on harms of treatment was restricted to studies of syphilis treatment during pregnancy … Eligible treatment harms included allergic reaction, premature labor, Jarisch-Herxheimer reaction, fetal … Although based on small studies,we found estimates of penicillin treatment harms that could be used for … Studies of other treatments in pregnant persons are lacking
None
2 Studies (single-group cohorts … IHR among low-risk persons undergoing penicillin provocation: 1/40 (2.5%)
Incomplete penicillin therapy
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/B73a4kJhxeaYyXK6gozbbY
May 24, 2022 - outcomes
Reporting bias not detected
Moderate for
benefit
VEGF inhibitors are considered first-line therapy … detected
Moderate for
no harm
VEGF inhibitors vs sham:
VEGF inhibitors are considered first-line therapy … Morphology and visual acuity in aflibercept and
ranibizumab therapy for neovascular age-related
macular … Oral zinc-therapy in age-related macular
degeneration: a double blind study. … Introducing
anti-vascular endothelial growth factor therapies
for AMD did not raise risk of myocardial
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/obesity-in-children-and-adolescents-screening
June 30, 2022 - combination:
Behavioral-based interventions (e.g., behavior modification, cognitive behavioral therapy … initiation of intervention (i.e., death or medical issue requiring hospitalization or urgent medical treatment … ) or other treatment-related harms reported in trials meeting inclusion criteria for intermediate or … Serious harms are events resulting in death, hospitalization, or the need for urgent medical treatment … Such studies include those in which allocation occurs in the course of usual treatment decisions or according
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ph_fauqHQjmrSqPAWKrARA
September 28, 2021 - Studies limited to persons seeking
fertility treatments were not included. … The gestational age at which aspirin therapy
was initiated across the trials varied substantially, with … b Median (range).
c Treatment time of day randomly assigned (morning, afternoon, or evening).
d Treatment … Low-dose aspirin therapy to prevent preeclampsia. … Pre-eclampsia:
screening and aspirin therapy for prevention of
pre-eclampsia.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cardiovascular/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
April 11, 2016 - The 11 primary prevention studies are heterogeneous in terms of aspirin dose; duration of therapy; baseline … conclude that the cardiovascular-related benefits (that is, nonfatal MI) occur during the first 5 years of therapy … AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients with Coronary and other Atherosclerotic … Early Treatment Diabetic Retinopathy Study report 14. ETDRS Investigators. … Primary and secondary prevention of cardiovascular disease: Antithrombotic Therapy and Prevention of
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/usptf-annual-report-congress-2018%20(1).pdf
January 01, 2018 - identifying tools that can accurately assess people’s
risk for a specific disease; and the effectiveness of treatments … Considerations for Implementation: To determine whether a patient is a candidate for statin
therapy, … Considerations for Implementation: To determine whether a patient is a candidate for statin
therapy, … D
Hormone Therapy With Combined Estrogen and Progestin in Postmenopausal Women:
Primary Prevention … Considerations for Implementation: To determine whether a patient is a candidate for statin
therapy,
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/_nVeFxDCT9L-_cnDf_V3fK
July 17, 2018 - Given
that risk estimates are used to guide preventive therapy such as as-
pirin and statins,6,8-10 improved … and appraise updated evidence on the benefits and harms of
nontraditional risk factor assessment and therapy … for each KQ or method-
ological and clinical heterogeneity, including differences in out-
comes and treatments … initiate preventive therapies have been lowered to 7.5% or 10%, and
reported NRI will capture movement … In the absence of this evidence, studies in which preventive
therapies were guided by nontraditional
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/rtc2016rev_2%20(3).pdf
December 01, 2016 - cascade of additional followup tests (some of which are
invasive and could cause harm), unnecessary treatments … Potential harms also include side
effects or complications of treatments. … in racial/ethnic subpopulations
• The benefits and harms of aspirin therapy in adults younger than … , or not receiving treatment at all. … Screening and Treatment for Depression in Children
3.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/h8qcZeQ68AQPS9DemArgXX
July 13, 2021 - each included study, 1 investigator extracted pertinent informa-
tion about the populations, tests or treatments … participants from 1977 through 1997, when routine care for CVD pre-
vention would not have included treatments … now considered to be
current standard medical therapy. … Saxagliptin as initial therapy in treatment-naive
Indian adults with type 2 diabetes mellitus
inadequately … No negative effects of a multi-factorial, intensified
treatment on self-reported health status, treatment
-
www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/2023-12/2023-annual-report-to-congress.pdf
January 01, 2023 - • For suicide risk, more research is needed on the effectiveness of screening tests and treatments … • For all conditions, evidence is lacking on the most effective tools and treatments for screening … Hispanic/Latino persons or persons with depression, may
help determine whether culturally tailored therapies … persons or persons with depression, which may help determine the effectiveness of
culturally tailored therapies … (Grade A)
Hormone Therapy for the
Primary Prevention of Chronic
Conditions in Postmenopausal
Persons
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-adults-screening-and-management-2012
June 15, 2012 - Benefits of Detection and Early Intervention/Treatment
The USPSTF found adequate evidence that intensive … Effectiveness of Detection and/or Treatment
No new trials were identified that compared screening for … Both also recommend that weight-loss and weight-maintenance therapies should include a reduced-calorie … diet, increased physical activity, and behavioral therapy. … Effectiveness of primary care--relevant treatments for obesity in adults: a systematic evidence review
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary5/visual-impairment-in-children-ages-1-5-screening-2011
January 15, 2011 - There were too few trials of treatments to perform meta-analysis. … ); 6-h patching: 0.34 ( P = 0.09 vs no treatment); no treatment: 0.24 ( P = 0.11 vs both treatments … Search
Database: Ovid Medline
exp Amblyopia/dt, pc, th [Drug Therapy, Prevention & Control, Therapy … ]
exp Refractive Errors/dt, th, pc [Drug Therapy, Therapy, Prevention & Control]
1 or 2
limit 3 … The therapy of amblyopia: an analysis of the results of amblyopia therapy utilizing the pooled data of
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/J-vUTejXWsdp_d86zK4Gth
July 01, 2005 - Behavioral therapy in the treatment of pediatric
obesity. … Ten-year outcomes of behavioral family-based
treatment for childhood obesity. … A reduced-glycemic
load diet in the treatment of adolescent obesity. … Behavior therapy and
sibutramine for the treatment of adolescent
obesity: a randomized controlled trial … Insurance reimbursement for the
treatment of obesity in children.
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-children-and-adolescents-screening-2005
July 11, 2005 - Behavioral therapy in the treatment of pediatric obesity. … Ten-year outcomes of behavioral family-based treatment for childhood obesity. … A reduced-glycemic load diet in the treatment of adolescent obesity. … Behavior therapy and sibutramine for the treatment of adolescent obesity: a randomized controlled trial … Insurance reimbursement for the treatment of obesity in children.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/asymptomatic-bacteriuria-in-adults-screening-2008
July 15, 2008 - Benefits of Detection and Early Treatment
The detection and treatment of asymptomatic bacteriuria … Harms of Detection and Early Treatment
Potential harms associated with treatment of asymptomatic … Harms of Detection and Early Treatment: Potential harms associated with treatment for asymptomatic bacteriuria … predictive value in pregnant women to replace the urine culture as the preferred screening test. 2
Treatment … Pregnant women with asymptomatic bacteriuria should receive antibiotic therapy directed at the cultured
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary28/cognitive-impairment-in-older-adults-screening-2014
October 22, 2013 - English-language studies of fair to good quality, primary care–feasible screening instruments, and treatments … To evaluate adverse effects of treatments with evidence of benefit, we examined the systematic review … Our review of treatments focuses only on the benefits and harms in a subset of persons with mild to moderate … Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled … Nonpharmacological therapies in Alzheimer's disease: a systematic review of efficacy.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan34/sexually-transmitted-infections-behavioral-counseling-september-2014
May 15, 2013 - Biomedical HIV/STI prevention interventions (e.g., prophylactic vaccinations, antiretroviral therapy … Correctional facilities
School classrooms
Worksites
Substance abuse treatment … Sexually transmitted diseases treatment guidelines, 2010.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan18/drug-use-illicit-primary-care-interventions-for-children-and-adolescents-march-2014
May 15, 2013 - through primary care screening comparable with patients who are included in effective primary care treatment … included in the review
Detoxification, medically managed withdrawal, or opioid substitution therapy … (methadone maintenance programs)
Maintaining abstinence after substance use treatment for abuse … (pre-existing) social networks (e.g., worksites, churches, schools)
Inpatient/residential treatment … began (e.g., death, seizure, cardiovascular event, or other medical issue requiring urgent medical treatment
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/rhd-incompatibility-screening-1996
January 01, 1996 - before the widespread availability of D immunoglobulin, administration of an insufficient dose, or treatment … spectrophotometry has been found to correctly predict disease severity (i.e., cord hemoglobin and need for neonatal therapy … antibody screening at the first prenatal visit, before elective procedures such as amniocentesis and therapeutic … New approaches in the treatment of haemolytic disease of the fetus. … Rh immunoprophylaxis: is antepartum therapy desirable?