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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Wx_w92ukxeDvNShoRQXbhP
    September 06, 2016 - Treatment Recommendations for the treatment of LTBI are available from the CDC.17 Additional Approaches … group or rifapentine plus isoniazid with isoniazid alone and found that the combination therapy was noninferior … Treatment regimens for latent TB infection (LTBI). http://www.cdc.gov/tb/topic/treatment/ltbi.htm. 2016 … Efficacy of various durations of isoniazid preventive therapy for tuberculosis: five years of follow-up … Adverse events with 4 months of rifampin therapy or 9 months of isoniazid therapy for latent tuberculosis
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/fbQmoAPKeBekmJ7aqmALe5
    June 01, 2014 - Evidence shows that several drug therapies and nonpharmacologic interventions have a small effect on … Pharmacologic treatments approved by the U.S. … clinicians to anticipate problems patients may have in understanding and adhering to rec- ommended therapy … Pharmacologic treatments approved by the U.S. … Treatment of mild to moderate dementia with several drug therapies and nonpharmacologic interventions
  3. www.uspreventiveservicestaskforce.org/uspstf/recommendation/screening-for-prediabetes-and-type-2-diabetes
    August 24, 2021 - More US data are needed on the effects of lifestyle interventions and medical treatments for screen-detected … Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with … A randomised trial of the effect and cost-effectiveness of early intensive multifactorial therapy on … Long-term effects of intensive multifactorial therapy in individuals with screen-detected type 2 diabetes … Impact of intensive lifestyle and metformin therapy on cardiovascular disease risk factors in the Diabetes
  4. www.uspreventiveservicestaskforce.org/home/getfilebytoken/njteJ388DLVsY8RLcBTe_A
    February 25, 2020 - English-language studies of cognitive impairment screening instruments, and pharmacologic and nonpharmacologic treatments … they will benefit from being screened for dementia, in part because they believe there are effective treatments … Group and individual cognitive therapies in Alzheimer’s disease: the ETNA3 randomized trial. … of enhancing cognitive stimulation therapy with a carer training program. … Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled
  5. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/cognitive-impairment-in-older-adults-screening
    February 25, 2020 - English-language studies of cognitive impairment screening instruments, and pharmacologic and nonpharmacologic treatments … they will benefit from being screened for dementia, in part because they believe there are effective treatments … Group and individual cognitive therapies in Alzheimer’s disease: the ETNA3 randomized trial. … of enhancing cognitive stimulation therapy with a carer training program. … Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled
  6. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/osteoporosis-screening-june-2018
    November 05, 2015 - For adults with increased risk for osteoporotic fractures, treatment may reduce the likelihood of fractures … Treatment may result in harms (KQ 5). … What are the harms associated with treatment with pharmacotherapy? … Food and Drug Administration for the treatment or prevention of osteoporosis (including bisphosphonates … , estrogen agonists/antagonists, hormone therapy, calcitonin, parathyroid hormone, and RANKL inhibitors
  7. www.uspreventiveservicestaskforce.org/home/getfilebytoken/bF_Y9vcT3eNPdHjTxPZsUZ
    April 17, 2023 - medication or psychotherapy (eg, cognitive behavioral therapy or brief psychosocial counseling), alone … , and nonadherence to medi- cation and therapy.38,39 Racism and structural policies have contributed … behavioral therapy, or guided internet-based interventions did not increase the risk of harm, measured … Native American/Alaska Native persons or persons with de- pression, may help determine whether tailored therapies … Effect of offering care management or online dialectical behavior therapy skills training vs usual
  8. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-harms-of-screening-for-breast-cancer/breast-cancer-screening-january-2016
    January 11, 2016 - Overdiagnosed women may be harmed by unnecessary procedures and treatments as well as by the burden of … relevance was determined by practice setting, population, date of publication, and use of technologies and therapies … had extremely dense breasts and either were aged 40 to 49 years (65.5%) or used combination hormone therapy … Women who are overdiagnosed can be harmed by unnecessary procedures and treatments and by the burden … Outcomes of screening mammography by frequency, breast density, and postmenopausal hormone therapy.
  9. www.uspreventiveservicestaskforce.org/home/getfilebytoken/za7BqXMwT8BMz4Z_ygrvKm
    May 01, 2004 - hand, the potential benefits of screening (based on this model’s optimistic assumption that earlier treatment … Menopausal hormone replacement therapy and risk of ovarian cancer. JAMA. 2002;288(3):334–341. 9. … Estrogen replacement therapy and ovarian cancer mortality in a large prospective study of US women.
  10. www.uspreventiveservicestaskforce.org/home/getfilebytoken/3R9N4ojm9Sk7qk8ybD3LU6
    October 11, 2019 - or Interventions Pregnant persons with asymptomatic bacteriuria usually receive an- tibiotic therapy … There is inadequate direct evidence to determine the harms of screening and treatment. … Bacteriuria of pregnancy: results of treatment. … Therapy vs no therapy for bacteriuria in elderly ambulatory nonhospitalized women. … Antimicrobial treatment in diabetic women with asymptomatic bacteriuria.
  11. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
    September 28, 2021 - Studies limited to persons seeking fertility treatments were not included. … The gestational age at which aspirin therapy was initiated across the trials varied substantially, with … For individuals at increased risk of preeclampsia, daily low-dose aspirin therapy was associated with … Low-dose aspirin therapy to prevent preeclampsia. … Pre-eclampsia: screening and aspirin therapy for prevention of pre-eclampsia.
  12. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review93/syphilis-infection-screening-2004
    July 15, 2004 - are effective and rarely harmful, and prenatal antibiotic therapy is effective in preventing congenital … RCT 32 and a study conducted outside the U.S. 33 compared azithromycin and penicillin treatments in … reported that ceftriaxone is used clinically for treating syphilis in the U.S. 36 Value of augmented therapy … A multicenter RCT assessed 2 treatments for early syphilis: both groups received 2.4 million units … A randomized trial of enhanced therapy for early syphilis in patients with and without human immunodeficiency
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/8L5g-QzXLDnUofBUE457DN
    July 01, 2004 - are effective and rarely harmful, and prenatal antibiotic therapy is effective in preventing congenital … reported that ceftriaxone is used clinically for treating syphilis in the U.S.36 Value of augmented therapy … A multicenter RCT assessed 2 treatments for early syphilis: both groups received 2.4 million units of … A number of small studies on alternative treatments such as oral azithromycin have been published and … A randomized trial of enhanced therapy for early syphilis in patients with and without human immunodeficiency
  14. www.uspreventiveservicestaskforce.org/home/getfilebytoken/jmCXJwxefa67VY4NfD8gUg
    June 26, 2018 - Pharma- cologic treatments for osteoporosis inhibit osteoclastic bone re- sorption (antiresorptive agents … Eligible treatments included US Food and Drug Administration (FDA)– approved pharmacotherapy (specifically … Benefits of Treatment Key Question 4a. … Bone modeling and remodeling: potential as therapeutic targets for the treatment of osteoporosis. … Fracture risk and zoledronic acid therapy in men with osteoporosis.
  15. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary--html/cardiovascular-disease-screening-using-nontraditional-risk-assessment
    July 10, 2018 - Given that risk estimates are used to guide preventive therapy such as aspirin and statins, 6 , 8-10 … and appraise updated evidence on the benefits and harms of nontraditional risk factor assessment and therapy … studies for each KQ or methodological and clinical heterogeneity, including differences in outcomes and treatments … thresholds to initiate preventive therapies have been lowered to 7.5% or 10%, and reported NRI will … In the absence of this evidence, studies in which preventive therapies were guided by nontraditional
  16. www.uspreventiveservicestaskforce.org/uspstf/recommendation/lipid-disorders-in-children-screening-july-2016
    August 09, 2016 - Treatment and Interventions Interventions for dyslipidemia include lifestyle modification (eg, changes … coronary heart disease events; and early identification and intervention with cholesterol-lowering therapy … ezetimibe, studied in 2 RCTs), also showed smaller effects on levels of LDL-C in a trial of combination therapy … Patterns of lipid lowering therapy among children ages 8-20 years. … Ten-year follow-up after initiation of statin therapy in children with familial hypercholesterolemia.
  17. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/behavioral-counseling-interventions-promote-healthy-diet-physical-activity-weight-loss-prevent-cardiovascular-disease-adults
    November 02, 2023 - Interventions include but are not limited to behavior modification, cognitive behavioral therapy, or
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/LSbrGFWSvekVzhcxwjTuXv
    February 01, 2016 - Relevance was determined by practice setting, population, date of publication, and use of technologies and therapies … Morbidity Outcomes Screening Trials A Cochrane review compared treatments between randomized groups … indi- cated less extensive surgery, such as fewer total mas- tectomies and more breast conservation therapies … diagnosis of ductal carcinoma in situ was included in some studies (74, 76), resulting in less intensive therapiesTreatment Early detection of invasive breast cancer Reduced: Advanced disease Treatment morbidity
  19. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan4/autism-spectrum-disorder-in-young-children-screening
    June 20, 2013 - What is the effect of severity of ASD on treatment outcomes? … What are the harms of treatment for ASD in young children? … Are there adequate diagnostic and treatment resources to provide services to children who screen positive … older children, or adults or assessing general developmental screening KQs 4, 5:  Studies of treatments … with ASD and at least one child ages 12 to 36 months, and published since prior systematic review of therapies
  20. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/asymptomatic-bacteriuria-in-adults-screening
    September 24, 2019 - identified 5.0% of women who were screened with dip slide as positive for asymptomatic bacteriuria. 33 Treatments … women reported that there were no adverse drug reactions among the 49 women treated with nitrofurantoin therapy … treated with trimethoprim. 28 Another reported that 2 of 32 women (6%) assigned to daily ofloxacin therapyTherapy vs no therapy for bacteriuria in elderly ambulatory nonhospitalized women. … Urinary tract infections in pregnancy: old and new unresolved diagnostic and therapeutic problems.

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