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  1. www.uspreventiveservicestaskforce.org/uspstf/document/comparative-effectiveness-of-antiviral-treatment-for-hepatitis-c-virus-infection-in-adults-a-systematic-review/hepatitis-c-screening-2013
    November 15, 2012 - For regimens longer than 12 weeks, dual therapy was continued to the end of treatment. … Harms of Antiviral Treatments Six head-to-head trials of dual therapy with pegylated interferon alfa … more effective treatments. … in part on the effectiveness of available treatments 81 . … hepatocellular carcinoma, liver transplantation rates, and quality of life) and harms of antiviral therapies
  2. www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/file/supporting_documents/hormone-therapy-postmenopause-final-rec-bulletin.pdf
    November 01, 2022 - Task Force Issues Final Recommendation Statement on Hormone Therapy for Preventing Chronic Conditions … www.uspreventiveservicestaskforce.org Task Force Issues Final Recommendation Statement on Hormone Therapy … for Preventing Chronic Conditions in Postmenopausal People Hormone therapy should not be used by … Hormone therapy refers to the use of medication that contains female hormones, which naturally become … While hormone therapy may reduce the risk of some conditions, it also can lead to serious harms.
  3. www.uspreventiveservicestaskforce.org/home/getfilebytoken/o6pGCffkVCx24mNebJGCXg
    January 01, 2013 - For regimens longer than 12 weeks, dual therapy was continued to the end of treatment. … Harms of Antiviral Treatments Six head-to-head trials of dual therapy with pegylated interferon alfa … identify more effective treatments. … in part on the effectiveness of available treatments (81). … hepatocellular carcinoma, liver transplantation rates, and quality of life) and harms of antiviral therapies
  4. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hepatitis-b-virus-infection-screening
    December 15, 2020 - Based on 18 trials (n = 2972), antiviral therapy compared with placebo or no treatment was associated … therapies to achieve intermediate outcomes. … Antiviral Therapy vs Placebo or No Treatment Eighteen trials (n = 2972) reported effects of antiviral … Antiviral Therapy vs Placebo or No Treatment Seven randomized trials of antiviral therapy vs placebo … Antiviral Therapy vs Placebo or No Treatment There were no statistically significant differences between
  5. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hepatitis-c-screening
    March 02, 2020 - USPSTF review on HCV screening in adults 5 , 6 and a comparative effectiveness review on antiviral treatments … What is the effectiveness of currently recommended antiviral treatments in improving health outcomes … What is the effectiveness of currently recommended antiviral treatments in achieving an SVR in patients … What are the harms of currently recommended antiviral treatments? … Three studies focused on DAAs, 66 , 68 , 77 1 study evaluated interferon-based treatments and DAAs,
  6. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-pregnant-women/human-immunodeficiency-virus-hiv-infection-screening
    June 15, 2017 - . †  Harms of treatment include adverse maternal and infant outcomes associated with use of antiretroviral … therapy. … treatment interruption Comparisons KQs 1, 3: HIV screening vs. no screening KQ 2: Repeat … the USPSTF revised the analytic framework to differentiate the harms of screening from the harms of treatment … diagnostic staging step, and clarify that the evidence review will focus on the benefits and harms of treatment
  7. www.uspreventiveservicestaskforce.org/uspstf/document/screening-for-hiv-in-pregnant-women-evidence-summary/human-immunodeficiency-virus-hiv-infection-screening-2013
    November 15, 2012 - , with the widespread adoption of routine prenatal screening coupled with the use of more effective therapies … breastfeeding populations, because these may provide some information about the effectiveness of antiretroviral therapies … without treatment. … or treatment 22 , 23 , 25 . … in the United States and other developed countries, except for randomized trials of antiretroviral therapies
  8. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/human-immunodeficiency-virus-hiv-infection-pregnant-nonpregnant-adults
    November 30, 2023 - . † Harms of treatment include adverse effects associated with antiretroviral therapy, including cardiometabolic … test results, anxiety and effects of labeling, and partner discord, abuse, or violence. † Harms of treatment … and adults with chronic HIV regardless of CD4 count vs. treatment based on CD4 threshold on mortality … single-drug regimens; pregnant persons who discontinued ART during pregnancy; pregnant persons with treatment … Department of Health and Human Services Panel on Treatment of HIV During Pregnancy and Prevention of
  9. www.uspreventiveservicestaskforce.org/home/getfilebytoken/mTPBWPMDqfuWvodfd5R5Ms
    November 01, 2012 - update the 2005 USPSTF review, focusing on previ- ously identified research gaps and new evidence on treatments … with the widespread adoption of routine prenatal screening cou- pled with the use of more effective therapies … without treatment. … or treatment (22, 23, 25). … in the United States and other developed countries, except for randomized trials of antiretroviral therapies
  10. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/human-immunodeficiency-virus-hiv-infection-pregnant-nonpregnant-adults
    February 22, 2024 - . † Harms of treatment include adverse effects associated with antiretroviral therapy, including cardiometabolic … † Harms of treatment include adverse maternal and infant outcomes associated with use of antiretroviral … and adults with chronic HIV regardless of CD4 count vs. treatment based on CD4 threshold on mortality … single-drug regimens; pregnant persons who discontinued ART during pregnancy; pregnant persons with treatment … Department of Health and Human Services Panel on Treatment of HIV During Pregnancy and Prevention of
  11. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-nonpregnant-adolescents-and-adults/human-immunodeficiency-virus-hiv-infection-screening
    June 15, 2017 - . †  Harms of treatment include adverse effects associated with antiretroviral therapy, including cardiometabolic … studies KQ 5: Randomized, controlled trials and controlled observational studies; will consider treatment … diagnostic staging step, and clarify that the evidence review will focus on the benefits and harms of treatment … with antiretroviral therapy. … therapy regimens."
  12. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/statin-use-in-adults-preventive-medication
    August 23, 2022 - underprediction in disadvantaged communities 10 , 11 that could lead to underutilization of preventive therapiesTreatment and Statin Intensity There are limited data directly comparing the effects of different statin … , 31 No study directly compared treatment with statins titrated to attain a target cholesterol level … vs fixed-dose treatment strategies. … Effect of statin treatment vs usual care on primary cardiovascular prevention among older adults: the
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/TkWNoq6KQb3SoZ54gscLCQ
    July 25, 2016 - Based on 18 trials (n = 2972), antiviral therapy compared with placebo or no treatment was associated … therapies to achieve intermediate outcomes. … Antiviral Therapy vs Placebo or No Treatment Eighteen trials (n = 2972) reported effects of antiviral … Antiviral Therapy vs Placebo or No Treatment Seven randomized trials of antiviral therapy vs placebo … Antiviral Treatment vs Placebo or No Treatment on Health Outcomes Favors antiviral therapy Favors placebo
  14. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-pregnant-women1/human-immunodeficiency-virus-hiv-infection-screening
    June 11, 2019 - Main Outcomes and Measures: Mother-to-child transmission; harms of screening and treatment; screening … declined after the widespread adoption of routine prenatal screening, coupled with the use of effective therapies … Effectiveness of Treatment Key Question 4. … Harms of Treatment Key Question 5. … Comparative safety of antiretroviral treatment regimens in pregnancy.
  15. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/statin-use-in-adults-preventive-medication
    August 23, 2022 - Benefits of Statin Treatment Key Question 1a. … group, high crossover from usual care, and increased use of nonstatin therapies in the usual care group … Harms of Statin Treatment Key Question 2a. … by Treatment Intensity Key Question 3. … of secondary prevention, defined statin intensity inadequately, or included nonstatin lipid-lowering therapies
  16. www.uspreventiveservicestaskforce.org/home/getfilebytoken/vxPM4Bo9RXZGUDH6MWnDht
    May 01, 2013 - ) Fair (other therapies) Data on suicide deaths were insufficient. … ) Fair (other therapies) No trials directly reported harms; 4 of 11 trials related to key questions … Psychosocial versus pharmacological treatments for deliberate self harm. … , with direct therapeutic contact Comtois et al, 2011 (47) 19–62 (37) 62 Other therapy, without direct … direct therapeutic contact King et al, 2009 (78) 13–17 (16) 71 Improving treatment adherence without
  17. JAMA (pdf file)

    www.uspreventiveservicestaskforce.org/home/getfilebytoken/GcjfCZtGpACQMv2KScLbEu
    June 11, 2019 - MAIN OUTCOMES AND MEASURES Mother-to-child transmission; harms of screening and treatment; screening … declined after the widespread adoption of routine prenatal screening, coupled with the use of effective therapies … Effectiveness of Treatment Key Question 4. … Harms of Treatment Key Question 5. … Comparative safety of antiretroviral treatment regimens in pregnancy.
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/yw_rbA_nQrCnkaN8X5t56S
    January 01, 2001 - ● What are the adverse effects of diet or drug treatment? … What are the adverse effects of diet or drug treatment? … Effectiveness of Drug Therapy Effects of drug therapy on CHD events. … Drug therapy appears to have little effect on total mortality after 5 to 7 years of treatment in lower-risk … after 5 to 10 years of treatment; the incremental benefit from beginning therapy earlier is, therefore
  19. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening-2001
    April 09, 2001 - What are the adverse effects of diet or drug treatment? … Effectiveness of Drug Therapy Effects of drug therapy on CHD events. … Drug therapy appears to have little effect on total mortality after 5 to 7 years of treatment in lower-risk … after 5 to 10 years of treatment; the incremental benefit from beginning therapy earlier is, therefore … What are the adverse effects of diet or drug treatment?
  20. www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication
    August 23, 2022 - underprediction in disadvantaged communities 10 , 11 that could lead to underutilization of preventive therapies … , 31 No study directly compared treatment with statins titrated to attain a target cholesterol level … vs fixed-dose treatment strategies. … Trials that directly compare statin therapy titrated to target lipid levels vs fixed-dose therapy to … Effect of statin treatment vs usual care on primary cardiovascular prevention among older adults: the

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