-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
January 01, 2023 - , including opioid therapy, nonopioid
pharmacologic therapy, and nonpharmacologic therapy. … Interventions
• Research to identify effective
nonpharmacologic therapies for neuropathic
pain. … • Knee osteoarthritis: Exercise, cognitive
behavioral therapy (CBT). … • Hip osteoarthritis: Exercise, manual therapies. … to clarify the effectiveness of vertebroplasty,
specifically whether some sham interventions have
therapeutic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-treatments-chronic-pain-protocol.pdf
December 19, 2018 - Opioid Treatments for Chronic Pain Research Protocol
Evidence-based Practice Center Systematic Review … Protocol
Project Title: Opioid Treatments for Chronic Pain
I. … In patients with chronic pain, what is the comparative effectiveness of opioids
versus nonopioid therapies … Opiate Substitution Treatment/
30. … Treatment Outcome/
34.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement.pdf
February 05, 2025 - ,16 dialectical behavioral therapy,15
family therapy,17, 18 attachment-based therapies, and variations … a) What are the components of effective psychosocial treatments (e.g., frequency or
intensity of therapy … and/or aspects of the therapeutic modality)? … or
integrative health
interventions (e.g., light
therapy, supplements)
Comparators • Treatment … as usual
• Another psychosocial intervention
• Another pharmacological therapy
• Combination therapies
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-225-substance-abuse-adolescents-evidence-summary%20225%20Substance%20Use%20Adolescents.pdf
May 01, 2020 - Intensive behavioral interventions (that involve more than 2 encounters)
Family-focused therapies … use disorders and of pharmacological treatments
typically used for comorbid psychiatric illnesses. … , cognitive behavioral therapy,
psychoeducation, contingency management, peer group therapy, and intensive … ID=CRD42018115388
3
pharmacological treatments used to treat use disorders; and … Of the multiple intensive interventions, family-focused therapies were most effective;
they reduced
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
April 25, 2013 - The Dosing and Outcomes Study of
Erythropoiesis-Stimulating Therapies (DOSE) is one example. … There were 5 radiation
therapy and 5 chemo-radiation therapy trials included in the
overall survival … For those undergoing adjuvant therapy after
successful local treatment, these risks would decrease substantially … once
adjuvant therapy ends. … representation of circumstances that are otherwise complex – for example, dose,
escalation strategies, cancer therapies
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/psoriasis-chronic_research-protocol.pdf
January 10, 2012 - While biologic treatments may represent a treatment option with fewer adverse effects, there are
concerns … plaque psoriasis who are candidates
for systemic therapy or phototherapy when other therapies are … TNF-α Treatment of severe chronic plaque psoriasis in adults who are candidates for systemic
therapy … failed to respond to at least one systemic therapy or in patients for whom other
systemic therapies … and treatment of meningeal
leukemia; used alone or in combination therapy in the treatment of breast
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0404_01-14-2011.pdf
January 01, 2011 - Summary:
The nominator is interested in the effectiveness and comparative effectiveness of
medical treatments … Compare two newer drug therapies, both FDA approved, for the treatment of
PAH (inhaled treprostinil … and ambrisentan) to older treatments
b. … Compare combination drug therapies to monotherapy drug treatment
Pulmonary Arterial Hypertension … Based on disease etiology and severity of the disease, the timing and
optimal combinations of drug therapy
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0648-140819.pdf
June 24, 2014 - Does effectiveness of diet therapy differ according to patient baseline
demographic and co-morbid characteristics … Does effectiveness of diet therapy differ according to patient baseline diet
and fluid intake? … Does effectiveness of diet therapy differ according to uric acid level and
quantitative urine uric acid … In adults with a history of gout, what is the evidence that dietary therapies to reduce
risk of recurrent … In adults with a history of gout, what is the evidence that pharmacological therapies
to reduce risk
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
April 25, 2013 - Treatment strategies are geared toward chronic
treatment but misses some acute therapies. … other associations described for KQ 2 have little clinical
utility, failing to rise to the level of therapeutic … Previous studies have been designed to
examine short term efficacy of particular treatments. … therapies continue to be improved for
this disease. … KQ3 evaluates the RCTs completed for approved PAH-specific
therapies, both mono and combination therapies
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
March 01, 2022 - ,
including opioid therapy, nonopioid pharmacologic
therapy, and nonpharmacologic therapy. … o Hip osteoarthritis: Exercise, manual therapies. … , including denosumab
followed by bisphosphonate therapy, and anabolic
therapy (e.g., teriparatide … (e.g., teriparatide or
abaloparatide) followed by antiresorptive therapy
versus antiresorptive therapy … but still may lead to discontinuation of
therapy during treatment of up to 12 weeks
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1406.pdf
June 01, 2014 - , screening and diagnostics, therapeutics, surgery, programs, and
care delivery innovations that address … cognitive behavior therapies. … efficacy for suicidal ideation
and as an adjunct treatment to behavior and brain-stimulation therapies … added to existing therapies. … Therapeutic options in
treatment-resistant depression. Ann Med. 2011
Nov;43(7):512-30.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-draft-protocol.pdf
March 14, 2024 - ,16 dialectical behavioral therapy,15
family therapy,17, 18 attachment-based therapies, and variations … a) What are the components of effective psychosocial treatments (e.g., frequency or
intensity of therapy … and/or aspects of the therapeutic modality)? … or
integrative health
interventions (e.g., light
therapy, supplements)
Comparators • Treatment … as usual
• Another psychosocial intervention
• Another pharmacological therapy
• Combination therapies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_executive.pdf
April 01, 2012 - Available
therapies for RA include corticosteroids,
oral disease-modifying antirheumatic
drugs or … Treatment strategies for RA continue
to evolve. … Effectiveness Reviews,
the program supports systematic
appraisals of existing scientific
evidence regarding treatments … The Key Questions (KQs) are as
follows:
KQ1: For patients with RA, do drug therapies differ in
their … on
stage of disease, prior therapy, demographics, concomitant
therapies, or comorbidities?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0663-131114.pdf
April 10, 2013 - (e.g., electroconvulsive
therapy)
Comparator(s): Pharmacologic, psychotherapy, psychosocial interventions … , or depressive episodes;
prevention of recurrent bipolar episodes; reduced suicide risk; improved treatment … e.g., electroconvulsive therapy)
in specific types of bipolar episodes (e.g., mania, depression) and … phases of treatment
(e.g., acute, maintenance)? … Standard
pharmacological therapies for bipolar disorder can include mood stabilizing medications such
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
January 01, 2007 - Analytic framework for evaluating the effectiveness and safety of treatments for renal
artery stenosis … Analytic framework for evaluating the effectiveness and safety of treatments for renal
artery stenosis … Stents were used only rarely and medical therapies varied both
between and within studies. … were prospective, followed the
natural history of 721 patients who mostly received various medical therapies … Including a third RCT with a substantial treatment crossover (medical therapy
to angioplasty) at 3 months
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-testing-machine-learning-tool-chronic-pain.pdf
November 01, 2020 - of therapy, or the total duration of follow-up (including
the duration of therapy). … 9. exp Braces/
10. exp Mind-Body Therapies/
11. exp Acupuncture Therapy/
12. exp Rehabilitation … Opioid Treatments for Chronic Pain
KQ 1-3 (Treatment)
1. … MMPI-2 profiles and illness perception in
fibromyalgia syndrome: The role of therapeutic exercise as … Basic body awareness therapy or exercise
therapy for the treatment of chronic whiplash associated disorders
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder_executive.pdf
December 01, 2015 - , cognitive therapy
(CT), cognitive behavioral therapy (CBT),
interpersonal therapy, and psychodynamic … therapy)
• Psychodynamic therapies
• Third-wave cognitive behavioral therapies
Complementary and alternative … Second-Generation Antidepressants Versus Integrative
Therapies
The only type of integrative therapy … of second-step
therapies involving 182 patients whose treatment was
augmented with a second medication … No second-step therapy data at all exist that compare
SGA with CAM or exercise treatments.
-
effectivehealthcare.ahrq.gov/sites/default/files/s1.pdf
October 01, 2007 - from
the adverse drug effects of medications, suboptimal treatment response, inappropriate
choice of … therapy, and gaps in knowledge on the true effects of a therapy across all patient
populations and conditions … endpoints, detect rare adverse effects,
evaluate health outcomes over long periods, or compare all treatment … care providers, and policy makers for objective
information about the outcomes and effectiveness of therapeutic … Decisions about Effectiveness (DEcIDE) research
network and the Centers for Education and Research on Therapeutics
-
effectivehealthcare.ahrq.gov/sites/default/files/back.pdf
January 01, 2011 - man
with
metastatic melanoma sp multiple regimens
• Discussing possibility of another therapy … palliative chemotherapy
• Consequences: patient suffering, high
costs
• Increase in anticancer therapy … • Patients are willing to choose a palliative therapy for a level of benefit that is lower that
what … clinician would tolerate
• Patients would
have toxic treatment for…
o 1% chance of cure
Source … • Qualitative study of 13 pts with metastatic colon and pancreas cancer
• “Treatment”
was
seen
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
August 01, 2013 - Effectiveness Reviews,
the program supports systematic
appraisals of existing scientific
evidence regarding treatments … Research for CER 119,
“Treatment of Atrial Fibrillation,” focusing on the
treatment of AF through rate … There are also many novel invasive treatments for AF. … , and strategies for determining longer term
therapy given successful AF treatment … continued anticoagulant therapy
versus bridging therapies versus interruption of therapy
(i.e., stopping