-
effectivehealthcare.ahrq.gov/sites/default/files/s13.pdf
October 01, 2007 - Epidemiology, Center for Clinical Epidemiology and Biostatistics, Cen-
ter for Education and Research in Therapeutics … People
who receive a drug are different from people who do not, in
that they have an indication for therapy … address new
methods to evaluate drug safety and effectiveness (ie, to
generate the evidence needed therapeutic … Strom BL; The Centers for Education & Research on Therapeutics
(CERTs) Risk Assessment Workshop Participants … Risk assessment of
drugs, biologics, and therapeutic devices: current approaches and future
directions
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
January 30, 2012 - Therapeutic Options for Stroke Prevention in AF
Vitamin K antagonists (VKAs) are highly effective … (95% CI, 3 to 34 percent).15
The narrow therapeutic window for warfarin has clinical implications … are the comparative diagnostic accuracy and
impact on clinical decisionmaking (diagnostic thinking, therapeutic … are the comparative diagnostic accuracy and
impact on clinical decisionmaking (diagnostic thinking, therapeutic … prior stroke (by type of event)
o Patients with prior bleed (by type of bleed)
o Patients in the therapeutic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
October 27, 2017 - Therapeutic Options for Stroke Prevention in AF
Much of the focus of AF management has been on treatment … Major Therapeutic Options for Stroke Prevention in AF
Treatment Description
Vitamin K antagonists … Clinical tools and
individual risk factors
for assessment/
evaluation of ICH
Anticoagulation
therapy … admissions, outpatient office visits, ER visits,
prescription drug use)
o Long-term adherence to therapy … monitoring practices or visit frequency not used in typical practice, use of
substandard alternative therapy
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
May 01, 2013 - Electromagnetic therapy
Therapeutic ultrasound
Negative pressure wound
therapy
Light therapy
Laser … Electromagnetic therapy
Therapeutic ultrasound
Negative pressure wound
therapy
Light therapy
Laser … Electromagnetic therapy
Therapeutic ultrasound
Negative pressure wound
therapy
Insufficient Due … There was also low-strength
evidence indicating that electromagnetic therapy,
therapeutic ultrasound … Systematic reviews
of wound care management: (5) beds; (6) compression; (7) laser
therapy, therapeutic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopausal-symptoms-protocol.pdf
October 15, 2024 - Hormone therapy (HT) is
the most effective treatment for some symptoms of menopause, including VMS and … • Nonhormonal treatments
such as vitamins and
herbs
• Energy-based therapies
(e.g., laser) … Treatments
6 exp Hormone Replacement Therapy/ 26898 Search terms:
hormone therapy
7 exp Estrogens … /tu [Therapeutic Use] 16314
8 exp Estradiol/tu [Therapeutic Use] 4551
9 exp Progesterone/tu … 15 Testosterone/tu [Therapeutic Use] 5249
16 Dehydroepiandrosterone/tu [Therapeutic Use] 789
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopausal-symptoms-protocol-final.pdf
October 15, 2024 - Hormone therapy (HT) is
the most effective treatment for some symptoms of menopause, including VMS and … Nonhormonal treatments
such as vitamins and
herbs
• Energy-based therapies
(e.g., laser)
• Behavioral … Treatments
6 exp Hormone Replacement Therapy/ 26898 Search terms:
hormone therapy
7 exp Estrogens … /tu [Therapeutic Use] 16314
8 exp Estradiol/tu [Therapeutic Use] 4551
9 exp Progesterone/tu … 15 Testosterone/tu [Therapeutic Use] 5249
16 Dehydroepiandrosterone/tu [Therapeutic Use] 789
-
effectivehealthcare.ahrq.gov/sites/default/files/s1.pdf
October 01, 2007 - from
the adverse drug effects of medications, suboptimal treatment response, inappropriate
choice of … therapy, and gaps in knowledge on the true effects of a therapy across all patient
populations and conditions … endpoints, detect rare adverse effects,
evaluate health outcomes over long periods, or compare all treatment … care providers, and policy makers for objective
information about the outcomes and effectiveness of therapeutic … Decisions about Effectiveness (DEcIDE) research
network and the Centers for Education and Research on Therapeutics
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0710-140625.pdf
January 08, 2014 - Nomination The nominator is interested in developing a clinical guideline on the management and
Summary: treatment … Intervention(s): Multiple treatment and management strategies including radical
nephrectomy (open and … associated with radical nephrectomy, partial nephrectomy, thermal
ablation, and active surveillance in the treatment … cases
of kidney cancer and 13,680 deaths from kidney cancer.
§ There are multiple management and treatment … Current clinical guidelines do not consider advancements such as new surgical
procedures and new therapeutic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol-amendment.pdf
January 08, 2025 - 'therapeutics':ti,ab,kw OR 'treatment':ti,ab,kw OR 'treatments':ti,ab,kw OR 'intervention':ti,ab,kw … " OR "drug therapy" OR
therapy OR therapeutics OR treatment OR therapy OR intervention OR interventions … "diet therapy" OR "drug therapy" OR therapy OR therapeutics OR treatment OR therapy OR
intervention … " OR "drug therapy" OR therapy OR therapeutics OR treatment OR
therapy OR intervention OR interventions … " OR "drug therapy" OR "Therapeutics" OR treatment OR therapy OR
intervention OR management OR program
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol.pdf
June 10, 2024 - 'therapeutics':ti,ab,kw OR 'treatment':ti,ab,kw OR 'treatments':ti,ab,kw OR 'intervention':ti,ab,kw … " OR "drug therapy" OR
therapy OR therapeutics OR treatment OR therapy OR intervention OR interventions … "diet therapy" OR "drug therapy" OR therapy OR therapeutics OR treatment OR therapy OR … " OR "drug therapy" OR therapy OR therapeutics OR treatment OR
therapy OR intervention OR interventions … " OR "drug therapy" OR "Therapeutics" OR treatment OR therapy OR
intervention OR management OR program
-
effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1412.pdf
December 01, 2014 - new (and new uses of existing) pharmaceuticals, medical
devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and
care delivery innovations that address … Off-label intranasal oxytocin for treatment of autism
spectrum disorders
No high-impact potential … Presently, behavioral therapies and pharmaceutical treatments are
used to improve various symptoms … ES-3
Eligible Topic Not Deemed High Impact
Off-label intranasal oxytocin for treatment of autism
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
February 01, 2008 - In ‘Arm A’
carbamazepine was compared with other newer antiepileptic treatments (i.e. gabapentin,
lamotrigine … effectiveness review of the efficacy, tolerability and safety of older versus newer
antiepileptic treatments … status (if applicable), drug class, BCS
class), comorbidities, and use of concurrent standard medical therapies … of Therapeutics and
Technology Assessment Subcommittee and Quality
Standards Subcommittee of the American … Therapeutics and Technology Assessment
Subcommittee, American Academy of Neurology.
-
effectivehealthcare.ahrq.gov/sites/default/files/decide16final-mortality-risk-in-copd-pts-using-theophylline.pdf
December 01, 2009 - results of short-term clinical trials of intermediate
endpoints and expert consensus.2,3 For some treatments … therapy. … Of these, 35.5% had a level in the therapeutic range. … there has been a lack of information on the effectiveness of theophylline in COPD
compared to other therapies … Salmeterol plus theophylline combination
therapy in the treatment of COPD.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-management_research.pdf
December 01, 2009 - results of short-term clinical trials of intermediate
endpoints and expert consensus.2,3 For some treatments … therapy. … Of these, 35.5% had a level in the therapeutic range. … there has been a lack of information on the effectiveness of theophylline in COPD
compared to other therapies … Salmeterol plus theophylline combination
therapy in the treatment of COPD.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0351_05-10-2010.pdf
January 01, 2010 - and associated abnormalities and their impact on treatment and
outcomes. … cryptorchidism (undescended testicle)
Intervention(s): diagnostic methods (imaging, laparoscopy), hormone therapy … , surgical
therapy, specific surgical techniques, early treatment, follow-up care, counseling of
patient … of
treatment, medical therapies, different surgical techniques
Outcome(s): diagnostic ability … uncertainty regarding appropriate
diagnostic approaches for cryptorchidism as well as appropriate therapeutic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
May 01, 2009 - This may result from the lack of entirely
acceptable and effective treatments, as well as their overlapping … is only limited support for the
use of these drugs in this condition, particularly as maintenance therapy … Even as an adjunct to
Effective Health Care Research Report Number 12
8
other therapies in … Depression
treatment during outpatient visits by U.S.
children and adolescents. … Effectiveness of adjunctive
antidepressant treatment for bipolar
depression.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-youth-disposition-comments.pdf
April 10, 2025 - Electroconvulsive therapy use in adolescents: a
systematic review. … Peer Reviewer #2 General Second, the conclusion that therapeutic alliance, non-
specific therapy factors … to treat Major Depressive Disorder (MDD) and
this recommendation is expanded on to include other
therapies … American
Academy of
Pediatrics
References Add references for all of the therapies described in Table … This might lead to a recommendation that an
experimental therapeutics approach would improve study
-
effectivehealthcare.ahrq.gov/products/diabetes-oral-drugs-safety-knowledge-gaps/research
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
May 22, 2012 - great benefit to practicing
physicians in helping them select the best patients for each available therapeutic … Patients
will benefit from more robust data on the comparative safety and effectiveness of different
therapeutic … KQ 6: What are the comparative diagnostic accuracy, diagnostic thinking, therapeutic, and
patient outcome … Protocol Version 11 Page 8
Diagnostic accuracy efficacy, diagnostic thinking efficacy, therapeutic … parameters
Outcome Measures:
• Diagnostic accuracy efficacy
• Diagnostic thinking efficacy
• Therapeutic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
November 22, 2011 - standard clopidogrel dosing, increased
clopidogrel dosing, and non–clopidogrel-based antiplatelet therapies … testing
for CYP2C19
variants
Test-guided
antiplatelet
therapy
Treatment with
antiplatelet … therapy
Phenotypic
testing for
platelet
response
Test-guided
change of
treatment
KQ3a … Treatment with
antiplatelet therapy
Adverse effects
of test-directed
treatment
KQ 1c, 2c, … the
therapeutic strategy (if the treatment response is deemed to be inadequate).